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Erschienen in: Indian Journal of Pediatrics 7/2019

24.04.2019 | Scientific Letter

Acute Lymphoblastic Leukemia Occurring Five Years After Onset of Steroid Resistant Nephrotic Syndrome

verfasst von: G. R. Jaikumar, Sriram Krishnamurthy, C. G. Delhi Kumar, S. V. Dhurva Sandeep, Biswajit Dubashi, Debdatta Basu

Erschienen in: Indian Journal of Pediatrics | Ausgabe 7/2019

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Excerpt

To the Editor: An eight-year-old boy was being treated for idiopathic steroid resistant nephrotic syndrome (NS) since 3 y of age. The renal biopsy showed Minimal Change Disease. He was treated with intravenous cyclophosphamide pulses (cumulative dose 3 g/m2, equivalent to 160 mg/kg) without remission; and thereafter, cyclosporin for two years, being in partial remission. Later, due to cyclosporin toxicity (severe gum hypertrophy and hirsutism, although serum creatinine and magnesium continued to be normal), intravenous rituximab was administered followed by mycophenolate mofetil (MMF) and prednisolone. He showed marked reduction in proteinuria, with no edema. The complete blood counts (CBC) and serum creatinine were monitored 3-monthly and remained normal. …
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Metadaten
Titel
Acute Lymphoblastic Leukemia Occurring Five Years After Onset of Steroid Resistant Nephrotic Syndrome
verfasst von
G. R. Jaikumar
Sriram Krishnamurthy
C. G. Delhi Kumar
S. V. Dhurva Sandeep
Biswajit Dubashi
Debdatta Basu
Publikationsdatum
24.04.2019
Verlag
Springer India
Erschienen in
Indian Journal of Pediatrics / Ausgabe 7/2019
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-019-02954-z

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