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Erschienen in: Journal of Gastrointestinal Surgery 8/2015

01.08.2015 | Original Article

Acute Mesenteric Ischemia Is a More Common Cause than Expected of Acute Abdomen in the Elderly

verfasst von: Jussi M. Kärkkäinen, Tiina T. Lehtimäki, Hannu Manninen, Hannu Paajanen

Erschienen in: Journal of Gastrointestinal Surgery | Ausgabe 8/2015

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Abstract

Background

The incidence of acute mesenteric ischemia (AMI) increases exponentially with age. The significance of AMI as a differential diagnosis in elderly patients with acute abdomen may be underestimated.

Methods

Consecutive patients hospitalized for AMI between 2009 and 2013 were retrospectively identified in a well-defined population. Acute appendicitis, ruptured abdominal aortic aneurysm, acute pancreatitis, and acute cholecystitis were used as reference diagnoses, and the age-specific incidence rates were calculated. In addition, long-term mortality risk was assessed for AMI survivors.

Results

The in-hospital incidence rates of AMI, acute obstructive mesenteric ischemia, and non-obstructive mesenteric ischemia were 7.3, 4.5, and 2.0/100,000/year, respectively. AMI was more common than ruptured abdominal aortic aneurysm, and the age-specific incidence of AMI was higher than the incidence of acute appendicitis in patients over age 75 years with acute abdomen. During the follow-up, the age-adjusted risk of death was 1.8 times higher in AMI survivors than in survivors of acute cholecystitis.

Conclusion

AMI may be a more common cause of acute abdomen in elderly patients than is generally thought, emphasizing the importance of performing urgent computed tomography with contrast enhancement preferably in arterial and venous phases in these patients.
Literatur
1.
Zurück zum Zitat Acosta S. Epidemiology of mesenteric vascular disease: clinical implications. Semin Vasc Surg 2010;23(1):4–8.PubMedCrossRef Acosta S. Epidemiology of mesenteric vascular disease: clinical implications. Semin Vasc Surg 2010;23(1):4–8.PubMedCrossRef
2.
Zurück zum Zitat Acosta S, Ogren M, Sternby NH, Bergqvist D, Björck M. Incidence of acute thrombo-embolic occlusion of the superior mesenteric artery—a population-based study. Eur J Vasc Endovasc Surg 2004;27(2):145–50.PubMedCrossRef Acosta S, Ogren M, Sternby NH, Bergqvist D, Björck M. Incidence of acute thrombo-embolic occlusion of the superior mesenteric artery—a population-based study. Eur J Vasc Endovasc Surg 2004;27(2):145–50.PubMedCrossRef
3.
Zurück zum Zitat Acosta S, Ögren M, Sternby N-H, Bergqvist D, Björck M: Fatal nonocclusive mesenteric ischaemia: population-based incidence and risk factors. J Intern Med 2006;259:305–313.PubMedCrossRef Acosta S, Ögren M, Sternby N-H, Bergqvist D, Björck M: Fatal nonocclusive mesenteric ischaemia: population-based incidence and risk factors. J Intern Med 2006;259:305–313.PubMedCrossRef
4.
Zurück zum Zitat Acosta S, Ögren M, Sternby N-H, Bergqvist D, Björck M: Mesenteric venous thrombosis with transmural intestinal infarction: a population-based study. J Vasc Surg 2005;41:59–63.PubMedCrossRef Acosta S, Ögren M, Sternby N-H, Bergqvist D, Björck M: Mesenteric venous thrombosis with transmural intestinal infarction: a population-based study. J Vasc Surg 2005;41:59–63.PubMedCrossRef
5.
Zurück zum Zitat Acosta S, Björck M. Acute thrombo-embolic occlusion of the superior mesenteric artery: a prospective study in a well defined population. Eur J Vasc Endovasc Surg 2003;26:179–183.PubMedCrossRef Acosta S, Björck M. Acute thrombo-embolic occlusion of the superior mesenteric artery: a prospective study in a well defined population. Eur J Vasc Endovasc Surg 2003;26:179–183.PubMedCrossRef
6.
Zurück zum Zitat Acosta S, Wadman M, Syk I, Elmståhl S, Ekberg O: Epidemiology and prognostic factors in acute superior mesenteric artery occlusion—a population-based study. J Gastrointest Surg 2010;14(4):628–35.PubMedCrossRef Acosta S, Wadman M, Syk I, Elmståhl S, Ekberg O: Epidemiology and prognostic factors in acute superior mesenteric artery occlusion—a population-based study. J Gastrointest Surg 2010;14(4):628–35.PubMedCrossRef
7.
Zurück zum Zitat Strömberg C, Johansson G, Adolfsson A. Acute abdominal pain: diagnostic impact of immediate CT scanning. World J Surg 2007;31(12):2347–54.PubMedCrossRef Strömberg C, Johansson G, Adolfsson A. Acute abdominal pain: diagnostic impact of immediate CT scanning. World J Surg 2007;31(12):2347–54.PubMedCrossRef
8.
Zurück zum Zitat Ilves I, Paajanen HE, Herzig KH, Fagerström A, Miettinen PJ. Changing incidence of acute appendicitis and nonspecific abdominal pain between 1987 and 2007 in Finland. World J Surg 2011;35(4):731–8.PubMedCrossRef Ilves I, Paajanen HE, Herzig KH, Fagerström A, Miettinen PJ. Changing incidence of acute appendicitis and nonspecific abdominal pain between 1987 and 2007 in Finland. World J Surg 2011;35(4):731–8.PubMedCrossRef
10.
Zurück zum Zitat Kärkkäinen JM, Lehtimäki TT, Saari P, Hartikainen J, Rantanen T, Paajanen H, Manninen H. Endovascular therapy as a primary revascularization modality in acute mesenteric ischemia. Cardiovasc Intervent Radiol 2015. doi:10.1007/s00270-015-1064-9. Kärkkäinen JM, Lehtimäki TT, Saari P, Hartikainen J, Rantanen T, Paajanen H, Manninen H. Endovascular therapy as a primary revascularization modality in acute mesenteric ischemia. Cardiovasc Intervent Radiol 2015. doi:10.​1007/​s00270-015-1064-9.
11.
Zurück zum Zitat Oliva IB, Davarpanah AH, Rybicki FJ, Desjardins B, Flamm SD, Francois CJ et al. ACR appropriateness criteria (R) imaging of mesenteric ischemia. Abdom Imaging 2013;38(4):714–719.PubMedCrossRef Oliva IB, Davarpanah AH, Rybicki FJ, Desjardins B, Flamm SD, Francois CJ et al. ACR appropriateness criteria (R) imaging of mesenteric ischemia. Abdom Imaging 2013;38(4):714–719.PubMedCrossRef
12.
Zurück zum Zitat Wadman M, Block T, Ekberg O, Syk I, Elmstahl S, Acosta S. Impact of MDCT with intravenous contrast on the survival in patients with acute superior mesenteric artery occlusion. Emerg Radiol 2010;17:171–178.PubMedCrossRef Wadman M, Block T, Ekberg O, Syk I, Elmstahl S, Acosta S. Impact of MDCT with intravenous contrast on the survival in patients with acute superior mesenteric artery occlusion. Emerg Radiol 2010;17:171–178.PubMedCrossRef
13.
Zurück zum Zitat Firetto MC, Lemos AA, Marini A, Avesani EC, Biondetti PR. Acute bowel ischemia: analysis of diagnostic error by overlooked findings at MDCT angiography. Emerg Radiol 2013;20:139–47.PubMedCrossRef Firetto MC, Lemos AA, Marini A, Avesani EC, Biondetti PR. Acute bowel ischemia: analysis of diagnostic error by overlooked findings at MDCT angiography. Emerg Radiol 2013;20:139–47.PubMedCrossRef
14.
Zurück zum Zitat Heikkinen M, Salenius JP, Auvinen O. Ruptured abdominal aortic aneurysm in a well-defined geographic area. J Vasc Surg 2002;36(2):291–6.PubMedCrossRef Heikkinen M, Salenius JP, Auvinen O. Ruptured abdominal aortic aneurysm in a well-defined geographic area. J Vasc Surg 2002;36(2):291–6.PubMedCrossRef
15.
Zurück zum Zitat Kuulasmaa K, Tunstall-Pedoe H, Dobson A, Fortmann S, Sans S, Tolonen H et al. Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations. Lancet 2000;355:675–87.PubMedCrossRef Kuulasmaa K, Tunstall-Pedoe H, Dobson A, Fortmann S, Sans S, Tolonen H et al. Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations. Lancet 2000;355:675–87.PubMedCrossRef
16.
Zurück zum Zitat Borodulin K, Vartiainen E, Peltonen M, Jousilahti P, Juolevi A, Laatikainen T et al. Forty-year trends in cardiovascular risk factors in Finland. Eur J Public Health 2014 (Published Online). Borodulin K, Vartiainen E, Peltonen M, Jousilahti P, Juolevi A, Laatikainen T et al. Forty-year trends in cardiovascular risk factors in Finland. Eur J Public Health 2014 (Published Online).
17.
Zurück zum Zitat Salomaa V, Havulinna AS, Koukkunen H, Kärjä-Koskenkari P, Pietilä A, Mustonen J et al. Aging of the population may not lead to an increase in the numbers of acute coronary events: a community surveillance study and modelled forecast of the future. Heart 2013;99(13):954–9.PubMedCrossRef Salomaa V, Havulinna AS, Koukkunen H, Kärjä-Koskenkari P, Pietilä A, Mustonen J et al. Aging of the population may not lead to an increase in the numbers of acute coronary events: a community surveillance study and modelled forecast of the future. Heart 2013;99(13):954–9.PubMedCrossRef
18.
Zurück zum Zitat Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL et al. ACC/AHA 2005 practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. Circulation 2006;113(11):463–654.CrossRef Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL et al. ACC/AHA 2005 practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. Circulation 2006;113(11):463–654.CrossRef
Metadaten
Titel
Acute Mesenteric Ischemia Is a More Common Cause than Expected of Acute Abdomen in the Elderly
verfasst von
Jussi M. Kärkkäinen
Tiina T. Lehtimäki
Hannu Manninen
Hannu Paajanen
Publikationsdatum
01.08.2015
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Surgery / Ausgabe 8/2015
Print ISSN: 1091-255X
Elektronische ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-015-2830-3

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