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Erschienen in: Journal of Anesthesia 4/2016

07.05.2016 | Original Article

Acute pain trajectories and the persistence of post-surgical pain: a longitudinal study after total hip arthroplasty

verfasst von: M. Gabrielle Pagé, Joel Katz, Kathryn Curtis, Noga Lutzky-Cohen, E. Manolo Romero Escobar, Hance A. Clarke

Erschienen in: Journal of Anesthesia | Ausgabe 4/2016

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Abstract

Purpose

The aim of this study was to explore acute movement-evoked postoperative pain intensity trajectories over the first 5 days after total hip arthroplasty (THA) and to examine how these pain trajectories are associated with pain-related outcomes 6 weeks and 6 months later.

Methods

A total of 150 adult patients [72 women (48.0 %); mean age 60.0 ± 9.2 (standard deviation) years] completed pain questionnaires preoperatively, several times daily postoperatively until hospital discharge, and 6 weeks and 6 months after surgery.

Results

Results showed that the best model had four different acute postoperative pain trajectories and a significant quadratic term. The trajectories varied in terms of initial pain intensity levels and rates of decline/increase in pain over the first 4 postoperative days. Significant predictors of pain trajectory membership were preoperative pain disability and anxiety as well as cumulative morphine consumption 24 h following surgery. Pain trajectories were significantly associated with levels of pain intensity and anxiety at 6 weeks but not at 6 months postoperatively.

Conclusion

This study showed that during the postoperative period patients differed in terms of pain intensity profiles and that these differences were associated with outcomes for up to 6 weeks following surgery. Pain trajectories were not predictive of persistent postoperative pain status at 6 months. Nonetheless, these results highlight the importance of patient heterogeneity in acute postoperative pain and pain-related outcomes months after THA.
Literatur
2.
Zurück zum Zitat Nwachukwu BU, McCormick F, Provencher MT, Roche M, Rubash HE. A comprehensive analysis of medicare trends in utilization and hospital economics for total knee and hip arthroplasty from 2005 to 2011. J Arthroplasty. 2015;30(1):15–8.CrossRefPubMed Nwachukwu BU, McCormick F, Provencher MT, Roche M, Rubash HE. A comprehensive analysis of medicare trends in utilization and hospital economics for total knee and hip arthroplasty from 2005 to 2011. J Arthroplasty. 2015;30(1):15–8.CrossRefPubMed
3.
Zurück zum Zitat Beswick AD, Wylde V, Gooberman-Hill R, Blom A, Dieppe P. What proportion of patients report long-term pain after total hip or knee replacement for osteoarthritis? A systematic review of prospective studies in unselected patients. BMJ Open. 2012;2(1):e000435.CrossRefPubMedPubMedCentral Beswick AD, Wylde V, Gooberman-Hill R, Blom A, Dieppe P. What proportion of patients report long-term pain after total hip or knee replacement for osteoarthritis? A systematic review of prospective studies in unselected patients. BMJ Open. 2012;2(1):e000435.CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Werner MU, Kongsgaard UEI. Defining persistent post-surgical pain: is an update required? Br J Anaesth. 2014;113(1):1–4.CrossRefPubMed Werner MU, Kongsgaard UEI. Defining persistent post-surgical pain: is an update required? Br J Anaesth. 2014;113(1):1–4.CrossRefPubMed
5.
Zurück zum Zitat Katz J, Seltzer Z. Transition from acute to chronic postsurgical pain: risk factors and protective factors. Exp Rev Neurother. 2009;9(5):723–44.CrossRef Katz J, Seltzer Z. Transition from acute to chronic postsurgical pain: risk factors and protective factors. Exp Rev Neurother. 2009;9(5):723–44.CrossRef
6.
Zurück zum Zitat Katz J, Jackson M, Kavanagh BP, Sandler AN. Acute pain after thoracic surgery predicts long-term post-thoracotomy pain. Clin J Pain. 1996;12(1):50–5.CrossRefPubMed Katz J, Jackson M, Kavanagh BP, Sandler AN. Acute pain after thoracic surgery predicts long-term post-thoracotomy pain. Clin J Pain. 1996;12(1):50–5.CrossRefPubMed
7.
Zurück zum Zitat Perkins FM, Kehlet H. Chronic pain as an outcome of surgery. A review of predictive factors. Anesthesiology. 2000;93(4):1123–33.CrossRefPubMed Perkins FM, Kehlet H. Chronic pain as an outcome of surgery. A review of predictive factors. Anesthesiology. 2000;93(4):1123–33.CrossRefPubMed
8.
Zurück zum Zitat Katz J. One man’s risk factor is another man’s outcome: difference in risk factor profiles for chronic postsurgical pain maintenance vs transition. Pain. 2012;153(3):505–6.CrossRefPubMed Katz J. One man’s risk factor is another man’s outcome: difference in risk factor profiles for chronic postsurgical pain maintenance vs transition. Pain. 2012;153(3):505–6.CrossRefPubMed
9.
Zurück zum Zitat Clarke H, Kay J, Mitsakakis N, Katz J. Acute pain after total hip arthroplasty does not predict the development of chronic postsurgical pain 6 months later. J Anesth. 2010;24(4):537–43.CrossRefPubMed Clarke H, Kay J, Mitsakakis N, Katz J. Acute pain after total hip arthroplasty does not predict the development of chronic postsurgical pain 6 months later. J Anesth. 2010;24(4):537–43.CrossRefPubMed
10.
Zurück zum Zitat Chapman CR, Donaldson GW, Davis JJ, Bradshaw DH. Improving individual measurement of postoperative pain: the pain trajectory. J Pain. 2011;12(2):257–62.CrossRefPubMedPubMedCentral Chapman CR, Donaldson GW, Davis JJ, Bradshaw DH. Improving individual measurement of postoperative pain: the pain trajectory. J Pain. 2011;12(2):257–62.CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Lavand’homme P. The progression from acute to chronic pain. Curr Opin Anaesthesiol. 2011;24(5):545–50.CrossRefPubMed Lavand’homme P. The progression from acute to chronic pain. Curr Opin Anaesthesiol. 2011;24(5):545–50.CrossRefPubMed
12.
Zurück zum Zitat Bonnet A, Lavand’homme P, France M-N, Reding R, De Kock M. Identification du risque de douleur chronic après hépatectomie pour don de foie par les trajectoires de douleur. Ann Fr Anesth Réanim. 2012;31:945–9.CrossRefPubMed Bonnet A, Lavand’homme P, France M-N, Reding R, De Kock M. Identification du risque de douleur chronic après hépatectomie pour don de foie par les trajectoires de douleur. Ann Fr Anesth Réanim. 2012;31:945–9.CrossRefPubMed
13.
Zurück zum Zitat Bellamy N, Buchanan WW. A preliminary evaluation of the dimensionality and clinical importance of pain and disability in osteoarthritis of the hip and knee. Clin Rheumatol. 1986;5(2):231–41.CrossRefPubMed Bellamy N, Buchanan WW. A preliminary evaluation of the dimensionality and clinical importance of pain and disability in osteoarthritis of the hip and knee. Clin Rheumatol. 1986;5(2):231–41.CrossRefPubMed
15.
Zurück zum Zitat Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15(12):1833–40.PubMed Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15(12):1833–40.PubMed
16.
Zurück zum Zitat Roos EM, Klassbo M, Lohmander LS. WOMAC osteoarthritis index. Reliability, validity, and responsiveness in patients with arthroscopically assessed osteoarthritis. Western Ontario and MacMaster Universities. Scand J Rheumatol. 1999;28(4):210–5.CrossRefPubMed Roos EM, Klassbo M, Lohmander LS. WOMAC osteoarthritis index. Reliability, validity, and responsiveness in patients with arthroscopically assessed osteoarthritis. Western Ontario and MacMaster Universities. Scand J Rheumatol. 1999;28(4):210–5.CrossRefPubMed
17.
Zurück zum Zitat Dunbar MJ, Robertsson O, Ryd L, Lidgren L. Appropriate questionnaires for knee arthroplasty. Results of a survey of 3600 patients from The Swedish Knee Arthroplasty Registry. J Bone Joint Surg Br. 2001;83(3):339–44.CrossRefPubMed Dunbar MJ, Robertsson O, Ryd L, Lidgren L. Appropriate questionnaires for knee arthroplasty. Results of a survey of 3600 patients from The Swedish Knee Arthroplasty Registry. J Bone Joint Surg Br. 2001;83(3):339–44.CrossRefPubMed
18.
Zurück zum Zitat McConnell S, Kolopack P, Davis AM. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC): a review of its utility and measurement properties. Arthritis Rheum. 2001;45(5):453–61.CrossRefPubMed McConnell S, Kolopack P, Davis AM. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC): a review of its utility and measurement properties. Arthritis Rheum. 2001;45(5):453–61.CrossRefPubMed
19.
Zurück zum Zitat Wright JG, Young NL. A comparison of different indices of responsiveness. J Clin Epidemiol. 1997;50(3):239–46.CrossRefPubMed Wright JG, Young NL. A comparison of different indices of responsiveness. J Clin Epidemiol. 1997;50(3):239–46.CrossRefPubMed
20.
Zurück zum Zitat Brazier JE, Harper R, Munro J, Walters SJ, Snaith ML. Generic and condition-specific outcome measures for people with osteoarthritis of the knee. Rheumatology (Oxford). 1999;38(9):870–7.CrossRef Brazier JE, Harper R, Munro J, Walters SJ, Snaith ML. Generic and condition-specific outcome measures for people with osteoarthritis of the knee. Rheumatology (Oxford). 1999;38(9):870–7.CrossRef
21.
Zurück zum Zitat Roos EM, Roos HP, Lohmander LS. WOMAC Osteoarthritis Index—additional dimensions for use in subjects with post-traumatic osteoarthritis of the knee. Western Ontario and MacMaster Universities. Osteoarthr Cartil. 1999;7(2):216–21.CrossRefPubMed Roos EM, Roos HP, Lohmander LS. WOMAC Osteoarthritis Index—additional dimensions for use in subjects with post-traumatic osteoarthritis of the knee. Western Ontario and MacMaster Universities. Osteoarthr Cartil. 1999;7(2):216–21.CrossRefPubMed
22.
Zurück zum Zitat Bombardier C, Melfi CA, Paul J, Green R, Hawker G, Wright J, et al. Comparison of a generic and a disease-specific measure of pain and physical function after knee replacement surgery. Med Care. 1995;33[4 Suppl]:AS131–44.PubMed Bombardier C, Melfi CA, Paul J, Green R, Hawker G, Wright J, et al. Comparison of a generic and a disease-specific measure of pain and physical function after knee replacement surgery. Med Care. 1995;33[4 Suppl]:AS131–44.PubMed
23.
Zurück zum Zitat Bullens PH, van Loon CJ, de Waal Malefijt MC, Laan RF, Veth RP. Patient satisfaction after total knee arthroplasty: a comparison between subjective and objective outcome assessments. J Arthroplasty. 2001;16(6):740–7.CrossRefPubMed Bullens PH, van Loon CJ, de Waal Malefijt MC, Laan RF, Veth RP. Patient satisfaction after total knee arthroplasty: a comparison between subjective and objective outcome assessments. J Arthroplasty. 2001;16(6):740–7.CrossRefPubMed
24.
Zurück zum Zitat Robertsson O, Dunbar MJ. Patient satisfaction compared with general health and disease-specific questionnaires in knee arthroplasty patients. J Arthroplasty. 2001;16(4):476–82.CrossRefPubMed Robertsson O, Dunbar MJ. Patient satisfaction compared with general health and disease-specific questionnaires in knee arthroplasty patients. J Arthroplasty. 2001;16(4):476–82.CrossRefPubMed
25.
Zurück zum Zitat Pollard CA. Preliminary validity study of the pain disability index. Percept Mot Skills. 1984;59(3):974.CrossRefPubMed Pollard CA. Preliminary validity study of the pain disability index. Percept Mot Skills. 1984;59(3):974.CrossRefPubMed
26.
Zurück zum Zitat Tait RC, Pollard CA, Margolis RB, Duckro PN, Krause SJ. The Pain Disability Index: psychometric and validity data. Arch Phys Med Rehabil. 1987;68(7):438–41.PubMed Tait RC, Pollard CA, Margolis RB, Duckro PN, Krause SJ. The Pain Disability Index: psychometric and validity data. Arch Phys Med Rehabil. 1987;68(7):438–41.PubMed
27.
Zurück zum Zitat Chibnall JT, Tait RC. The Pain Disability Index: factor structure and normative data. Arch Phys Med Rehabil. 1994;75(10):1082–6.CrossRefPubMed Chibnall JT, Tait RC. The Pain Disability Index: factor structure and normative data. Arch Phys Med Rehabil. 1994;75(10):1082–6.CrossRefPubMed
28.
Zurück zum Zitat Tait RC, Chibnall JT. Factor structure of the pain disability index in workers compensation claimants with low back injuries. Arch Phys Med Rehabil. 2005;86(6):1141–6.CrossRefPubMed Tait RC, Chibnall JT. Factor structure of the pain disability index in workers compensation claimants with low back injuries. Arch Phys Med Rehabil. 2005;86(6):1141–6.CrossRefPubMed
29.
Zurück zum Zitat Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113(1–2):9–19.CrossRefPubMed Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113(1–2):9–19.CrossRefPubMed
30.
Zurück zum Zitat Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res. 2002;52(2):69–77.CrossRefPubMed Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res. 2002;52(2):69–77.CrossRefPubMed
31.
Zurück zum Zitat Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–70.CrossRefPubMed Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–70.CrossRefPubMed
32.
Zurück zum Zitat Clarke H, Pagé MG, McCartney C, Huang A, Stratford P, Andrion J, et al. Pregabalin reduces postoperative opioid consumption and pain for 1 week after hospital discharge, but does not affect function at 6 weeks or 3 months after total hip arthroplasty. Br J Anaesth. 2015;115(6):903–11.CrossRefPubMed Clarke H, Pagé MG, McCartney C, Huang A, Stratford P, Andrion J, et al. Pregabalin reduces postoperative opioid consumption and pain for 1 week after hospital discharge, but does not affect function at 6 weeks or 3 months after total hip arthroplasty. Br J Anaesth. 2015;115(6):903–11.CrossRefPubMed
33.
Zurück zum Zitat Asparouhov T, Muthen B. Multilevel mixture models. In: Hancock GR, Samuelsen KM, editors. Advances in latent variable mixture models. Charlotte: Information Age Publishing Inc; 2008. p. 27–51. Asparouhov T, Muthen B. Multilevel mixture models. In: Hancock GR, Samuelsen KM, editors. Advances in latent variable mixture models. Charlotte: Information Age Publishing Inc; 2008. p. 27–51.
34.
Zurück zum Zitat Muthen B, Asparouhov T. Growth mixture modeling: analysis with non-Gaussian random effects. In: Fitzmaurice G, Davidian M, Verbeke G, Molenberghs G, editors. Longitudinal data analysis. Boca Raton:Chapman & Hall/CRC Press; 2009. p. 143–165. Muthen B, Asparouhov T. Growth mixture modeling: analysis with non-Gaussian random effects. In: Fitzmaurice G, Davidian M, Verbeke G, Molenberghs G, editors. Longitudinal data analysis. Boca Raton:Chapman & Hall/CRC Press; 2009. p. 143–165.
35.
Zurück zum Zitat Muthen B, Shedden K. Finite mixture modeling with mixture outcomes using the EM algorithm. Biometrics. 1999;55:463–9.CrossRefPubMed Muthen B, Shedden K. Finite mixture modeling with mixture outcomes using the EM algorithm. Biometrics. 1999;55:463–9.CrossRefPubMed
37.
Zurück zum Zitat Team RC. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing; 2013. Team RC. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing; 2013.
38.
Zurück zum Zitat Akaike H. Information measures and model selection. Bull Int Stat Inst. 1983;44:277–91. Akaike H. Information measures and model selection. Bull Int Stat Inst. 1983;44:277–91.
39.
Zurück zum Zitat de Leeuw J. Introduction to Akaike (1973) information theory and an extension of the maximum likelihood principle. In: Kotz S, Johnson NL, editors. Breakthrough in statistics, vol. 1. London: Springer; 1992. p. 599–609. de Leeuw J. Introduction to Akaike (1973) information theory and an extension of the maximum likelihood principle. In: Kotz S, Johnson NL, editors. Breakthrough in statistics, vol. 1. London: Springer; 1992. p. 599–609.
40.
Zurück zum Zitat Lord FM, Novick MR. Statistical theories of mental test scores. Reading: Addison-Wesley; 1968. Lord FM, Novick MR. Statistical theories of mental test scores. Reading: Addison-Wesley; 1968.
41.
Zurück zum Zitat Ram N, Grimm KJ. Growth mixture modeling: a method for identifying differences in longitudinal change among unobserved groups. Int J Behav Dev. 2009;33(6):565–76.CrossRefPubMedPubMedCentral Ram N, Grimm KJ. Growth mixture modeling: a method for identifying differences in longitudinal change among unobserved groups. Int J Behav Dev. 2009;33(6):565–76.CrossRefPubMedPubMedCentral
43.
Zurück zum Zitat Hertzog C, Lindenberger U, Ghisletta P, Oertzen T. On the power of multivariate latent growth curve models to detect correlated change. Psychol Methods. 2006;11(3):244–52.CrossRefPubMed Hertzog C, Lindenberger U, Ghisletta P, Oertzen T. On the power of multivariate latent growth curve models to detect correlated change. Psychol Methods. 2006;11(3):244–52.CrossRefPubMed
44.
Zurück zum Zitat Steyaert A, De Kock M. Chronic postsurgical pain. Curr Opin Anaesthesiol. 2012;25(5):584–8.CrossRefPubMed Steyaert A, De Kock M. Chronic postsurgical pain. Curr Opin Anaesthesiol. 2012;25(5):584–8.CrossRefPubMed
45.
Zurück zum Zitat Liu SS, Buvanendran A, Rathmell JP, Sawhney M, Bae JJ, Moric M, et al. Predictors for moderate to severe acute postoperative pain after total hip and knee replacement. Int Orthop. 2012;36(11):2261–7.CrossRefPubMedPubMedCentral Liu SS, Buvanendran A, Rathmell JP, Sawhney M, Bae JJ, Moric M, et al. Predictors for moderate to severe acute postoperative pain after total hip and knee replacement. Int Orthop. 2012;36(11):2261–7.CrossRefPubMedPubMedCentral
46.
Zurück zum Zitat Pinto PR, McIntyre T, Ferrero R, Almeida A, Araujo-Soares V. Predictors of acute postsurgical pain and anxiety following primary total hip and knee arthroplasty. J Pain. 2013;14(5):502–15.CrossRefPubMed Pinto PR, McIntyre T, Ferrero R, Almeida A, Araujo-Soares V. Predictors of acute postsurgical pain and anxiety following primary total hip and knee arthroplasty. J Pain. 2013;14(5):502–15.CrossRefPubMed
47.
Zurück zum Zitat Althaus A, Arranz Becker O, Neugebauer E. Distinguishing between pain intensity and pain resolution: using acute post-surgical pain trajectories to predict chronic post-surgical pain. Eur J Pain. 2014;18(4):513–21.CrossRefPubMed Althaus A, Arranz Becker O, Neugebauer E. Distinguishing between pain intensity and pain resolution: using acute post-surgical pain trajectories to predict chronic post-surgical pain. Eur J Pain. 2014;18(4):513–21.CrossRefPubMed
48.
Zurück zum Zitat Page MG, Katz J, Romero Escobar EM, Lutzky-Cohen N, Curtis K, Fuss S, et al. Distinguishing problematic from nonproblematic postsurgical pain: a pain trajectory analysis after total knee arthroplasty. Pain. 2015;156(3):460–8.CrossRefPubMed Page MG, Katz J, Romero Escobar EM, Lutzky-Cohen N, Curtis K, Fuss S, et al. Distinguishing problematic from nonproblematic postsurgical pain: a pain trajectory analysis after total knee arthroplasty. Pain. 2015;156(3):460–8.CrossRefPubMed
49.
Zurück zum Zitat Santaguida PL, Hawker GA, Hudak PL, Glazier R, Mahomed NN, Kreder HJ, et al. Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review. Can J Surg. 2008;51(6):428–36.PubMedPubMedCentral Santaguida PL, Hawker GA, Hudak PL, Glazier R, Mahomed NN, Kreder HJ, et al. Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review. Can J Surg. 2008;51(6):428–36.PubMedPubMedCentral
50.
Zurück zum Zitat Clarke H, Poon M, Weinrib A, Katznelson R, Wentlandt K, Katz J. Preventive analgesia and novel strategies for the prevention of chronic post-surgical pain. Drugs. 2015;75(4):339–51.CrossRefPubMed Clarke H, Poon M, Weinrib A, Katznelson R, Wentlandt K, Katz J. Preventive analgesia and novel strategies for the prevention of chronic post-surgical pain. Drugs. 2015;75(4):339–51.CrossRefPubMed
51.
Zurück zum Zitat Haroutiunian S, Nikolajsen L, Finnerup NB, Jensen TS. The neuropathic component in persistent postsurgical pain: a systematic literature review. Pain. 2013;154(1):95–102.CrossRefPubMed Haroutiunian S, Nikolajsen L, Finnerup NB, Jensen TS. The neuropathic component in persistent postsurgical pain: a systematic literature review. Pain. 2013;154(1):95–102.CrossRefPubMed
Metadaten
Titel
Acute pain trajectories and the persistence of post-surgical pain: a longitudinal study after total hip arthroplasty
verfasst von
M. Gabrielle Pagé
Joel Katz
Kathryn Curtis
Noga Lutzky-Cohen
E. Manolo Romero Escobar
Hance A. Clarke
Publikationsdatum
07.05.2016
Verlag
Springer Japan
Erschienen in
Journal of Anesthesia / Ausgabe 4/2016
Print ISSN: 0913-8668
Elektronische ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-016-2183-4

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