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Community Mental Health Journal

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01.01.2020 | Original Paper

Adherence to Antidepressants in Underserved Communities: A Comparison of Electronic Monitoring and Self-report Measures

verfasst von: Heather F. McClintock, Angela N. BeKampis, Erica Hartmann, Hillary R. Bogner

Erschienen in: Community Mental Health Journal | Ausgabe 4/2020

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Abstract

Nonadherence to antidepressants is widespread and poses a significant barrier to optimal management and treatment of depression in community settings. The objective of this study was to compare self-reported and electronic monitoring of adherence to antidepressants and to examine the relationship of these measures with depressive symptoms in a medically underserved community. Adherence to antidepressants was measured in 38 primary care patients from the West Philadelphia area using self-report and electronic monitoring (Medication Event Monitoring System caps). Self-report and electronic monitoring of antidepressant adherence showed fair agreement at baseline, slight agreement at 6 weeks, and slight agreement at 12 weeks. Adherence to antidepressants as assessed by electronic monitors was significantly associated with depression remission at 12 weeks [adjusted odds ratio 18.6, 95% confidence interval (1.05, 330.56)]. Compared with electronic monitoring, self-reported adherence tended to overestimate medication adherence to antidepressants. Adherence assessed by electronic monitoring was associated with depression remission.

Abada, S., Clark, L. E., Sinha, A. K., Xia, R., Pace-Murphy, K., Flores, R. J., et al. (2019). Medication regimen complexity and low adherence in older community-dwelling adults with substantiated self-neglect. Journal of Applied Gerontology,38(6), 866–883.CrossRef

Alegria, M., NeMoyer, A., Falgas Bague, I., Wang, Y., & Alvarez, K. (2018). Social determinants of mental health: Where we are and where we need to go. Current Psychiatry Reports,20(11), 95. https://doi.org/10.1007/s11920-018-0969-9.CrossRefPubMedPubMedCentral

Angst, J. (1988). Clinical course of affective disorders. Depressive Illness. https://doi.org/10.1007/978-3-642-73546-2_1.CrossRef

Barbui, C., Cipriani, A., Patel, V., Ayuso-Mateos, J. L., & van Ommeren, M. (2011). Efficacy of antidepressants and benzodiazepines in minor depression: Systematic review and meta-analysis. The British Journal of Psychiatry,198(1), 11–16. https://doi.org/10.1192/bjp.bp.109.076448.CrossRefPubMedPubMedCentral

Bauer, A., Parker, M., Schillinger, D., Katon, W., Adler, N., Adams, A., et al. (2014). Associations between antidepressant adherence and shared decision-making, patient-provider trust, and communication among adults with diabetes: Diabetes Study of Northern California (DISTANCE). Journal of General Internal Medicine,29(8), 1139–1147.CrossRef

Bosman, J., Ter Horst, P. G., Smit, J. P., Dijkstra, J. R., Beekhuis, H. R., Slingersland, R. J., et al. (2014). Adherence of antidepressants during pregnancy: MEMS compared with three other methods. Therapeutic Advances in Psychopharmacology,4(2), 61–69. https://doi.org/10.1177/2045125313511486.CrossRefPubMedPubMedCentral

Brown, M. T., & Bussell, J. K. (2011). Medication adherence: WHO cares? Mayo Clinic Proceedings,86(4), 304–314. https://doi.org/10.4065/mcp.2010.0575.CrossRefPubMedPubMedCentral

Campbell, J. P., Maxey, V. A., & Watson, W. A. (1995). Hawthorne effect: Implications for prehospital research. Annals of Emergency Medicine,26(5), 590–594.CrossRef

Choudhry, N. K., Shrank, W. H., Levin, R. L., Lee, J. L., Jan, S. A., Brookhart, M. A., et al. (2009). Measuring concurrent adherence to multiple related medications. The American Journal of Managed Care,15(7), 457–464.PubMedPubMedCentral

Cipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., … Geddes, J. R. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis. Lancet, 391(10128), 1357–1366. doi:10.1016/s0140-6736(17)32802-7.

Claxton, A. J., Cramer, J. B., & Pierce, C. (2001). A systematic review of the associations between dose regimens and medication compliance. Clinical Therapeutics,23(8), 1296–1310.CrossRef

Croghan, T. W., Lair, T. J., Engelhart, L., Crown, W. E., Copley-Merriman, C., Melfi, C. A., et al. (1997). Effect of antidepressant therapy on health care utilization and costs in primary care. Psychiatric Services (Washington, D. C.),48(11), 1420–1426. https://doi.org/10.1176/ps.48.11.1420.CrossRef

Crum, R. M., Anthony, J. C., Bassett, S. S., & Folstein, M. F. (1993). Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA,269(18), 2386–2391.CrossRef

de Vries McClintock, H. F., Boyle, K. B., Rooney, K., & Bogner, H. R. (2016). Diabetes and depression care: A randomized controlled pilot trial. American Journal of Health Behavior,40(4), 503–513. https://doi.org/10.5993/ajhb.40.4.12.CrossRefPubMed

Farmer, K. C. (1999). Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clinical Therapeutics,21(6), 1074–1090. https://doi.org/10.1016/s0149-2918(99)80026-5. (discussion 1073).CrossRefPubMed

Garber, M. C., Nau, D. P., Erickson, S. R., Aikens, J. E., & Lawrence, J. B. (2004). The concordance of self-report with other measures of medication adherence: A summary of the literature. Medical Care,42(7), 649–652.CrossRef

Garfield, S., Clifford, S., Eliasson, L., Barber, N., & Willson, A. (2011). Suitability of measures of self-reported medication adherence for routine clinical use: A systematic review. BMC Medical Research Methodology,11, 149. https://doi.org/10.1186/1471-2288-11-149.CrossRefPubMedPubMedCentral

George, C. F., Peveler, R. C., Heiliger, S., & Thompson, C. (2000). Compliance with tricyclic antidepressants: The value of four different methods of assessment. British Journal of Clinical Pharmacology,50(2), 166–171.CrossRef

Hashmi, S. K., Afridi, M. B., Abbas, K., Sajwani, R. A., Saleheen, D., Frossard, P. M., …, Ahmad, U. (2007). Factors associated with adherence to anti-hypertensive treatment in Pakistan. PLoS ONE, 2(3), e280. doi:10.1371/journal.pone.0000280.

Heckman, B. D., Catz, S. L., Heckman, T. G., Miller, J. G., & Kalichman, S. C. (2004). Adherence to antiretroviral therapy in rural persons living with HIV disease in the United States. AIDS Care,16(2), 219–230. https://doi.org/10.1080/09540120410001641066.CrossRefPubMed

Interian, A. (2010). A brief self-report measure to assess antidepressant adherence among Spanish-speaking Latinos. Journal of Clinical Psychopharmacology,30(6), 755–757. https://doi.org/10.1097/JCP.0b013e3181fb57f8.CrossRefPubMedPubMedCentral

Iribarren, S. J., Cato, K., Falzon, L., & Stone, P. W. (2017). What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions. PLoS ONE,12(2), e0170581.CrossRef

Kahn, R. S., Wise, P. H., Kennedy, B. P., & Kawachi, I. (2000). State income inequality, household income, and maternal mental and physical health: Cross sectional national survey. BMJ,321(7272), 1311–1315. https://doi.org/10.1136/bmj.321.7272.1311.CrossRefPubMedPubMedCentral

Kleinberg, A., Aluoja, A., & Vasar, V. (2013). Social support in depression: Structural and functional factors, perceived control and help-seeking. Epidemiology and Psychiatric Sciences,22(4), 345–353. https://doi.org/10.1017/s2045796013000504.CrossRefPubMed

Kroenke, K., Spitzer, R. L., & Williams, J. B. (2001). The PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine,16(9), 606–613.CrossRef

Lee, M. S., Lee, H. Y., Kang, S. G., Yang, J., Ahn, H., Rhee, M., …, Kim, S. H. (2010). Variables influencing antidepressant medication adherence for treating outpatients with depressive disorders. Journal of Affective Disorders, 123(1–3), 216–221. doi:10.1016/j.jad.2009.10.002.

Marlowe, D., & Crowne, D. P. (1961). Social desirability and response to perceived situational demands. Journal of Consulting Psychology,25, 109–115.CrossRef

McHorney, C. A. (1996). Measuring and monitoring general health status in elderly persons: Practical and methodological issues in using the SF-36 Health Survey. Gerontologist,36(5), 571–583.CrossRef

Melfi, C. A., Chawla, A. J., Croghan, T. W., Hanna, M. P., Kennedy, S., & Sredl, K. (1998). The effects of adherence to antidepressant treatment guidelines on relapse and recurrence of depression. Archives of General Psychiatry,55(12), 1128–1132.CrossRef

Nakonezny, P. A., Hughes, C. W., Mayes, T. L., Sternweis-Yang, K. H., Kennard, B. D., Byerly, M. J., et al. (2010). A comparison of various methods of measuring antidepressant medication adherence among children and adolescents with major depressive disorder in a 12-week open trial of fluoxetine. Journal of Child and Adolescent Psychopharmacology,20(5), 431–439. https://doi.org/10.1089/cap.2009.0108.CrossRefPubMedPubMedCentral

National Academies of Sciences, Engineering, and Medicine. (2016). A framework for educating health professionals to address the social determinants of health. Washington, DC: The National Academies Press.

Neath, I. (1993). Distinctiveness and serial position effects in recognition. Memory & Cognition,21(5), 689–698.CrossRef

Nguyen, T. M., La Caze, A., & Cottrell, N. (2014). What are validated self-report adherence scales really measuring?: A systematic review. British Journal of Clinical Pharmacology,77(3), 427–445. https://doi.org/10.1111/bcp.12194.CrossRefPubMedPubMedCentral

Odegard, P. S., & Gray, S. L. (2008). Barriers to medication adherence in poorly controlled diabetes mellitus. The Diabetes Educator,34(4), 692–697. https://doi.org/10.1177/0145721708320558.CrossRefPubMed

Olfson, M., Marcus, S. C., Tedeschi, M., & Wan, G. J. (2006). Continuity of antidepressant treatment for adults with depression in the United States. American Journal of Psychiatry,163(1), 101–108. https://doi.org/10.1176/appi.ajp.163.1.101.CrossRefPubMed

Osterberg, L. B. T. (2005). Adherence to medication. The New England Journal of Medicine,353(5), 487–497. https://doi.org/10.1056/NEJMra050100.CrossRefPubMed

Rapaport, M. H., & Judd, L. L. (1998). Minor depressive disorder and subsyndromal depressive symptoms: Functional impairment and response to treatment. Journal of Affective Disorders,48(2–3), 227–232.CrossRef

Rickles, N. M., & Svarstad, B. L. (2007). Relationships between multiple self-reported nonadherence measures and pharmacy records. Research in Social and Administrative Pharmacy,3(4), 363–377. https://doi.org/10.1016/j.sapharm.2006.11.001.CrossRefPubMed

Salazar-Fraile, J., Sempere-Verdu, E., Perez-Hoyos, S., Tabares-Seisdedos, R., & Gomez-Beneyto, M. (2018). Five interpersonal factors are predictive of the response to treatment of major depression with antidepressants in primary care. Frontiers in Psychiatry,9, 416. https://doi.org/10.3389/fpsyt.2018.00416.CrossRefPubMedPubMedCentral

Sansone, R. A., & Sansone, L. A. (2012). Antidepressant adherence: Are patients taking their medications? Innovations in Clinical Neuroscience,9(5–6), 41–46.PubMedPubMedCentral

Shi, L., Liu, J., Koleva, Y., Fonseca, V., Kalsekar, A., & Pawaskar, M. (2010). Concordance of adherence measurement using self-reported adherence questionnaires and medication monitoring devices. Pharmacoeconomics,28(12), 1097–1107. https://doi.org/10.2165/11537400-000000000-00000.CrossRefPubMed

Stadnyk, K., Calder, J., & Rockwood, K. (1998). Testing the measurement properties of the Short Form-36 Health Survey in a frail elderly population. Journal of Clinical Epidemiology,51(10), 827–835.CrossRef

Stewart, A. L. (1992). Measuring functioning and well-being: The medical outcomes study. Durham, NC: Duke University Press.

Stewart, A. L., Greenfield, S., Hays, R. D., Wells, K., Rogers, W. H., Berry, S. D., …,Ware, J. E., Jr. (1989). Functional status and well-being of patients with chronic conditions. Results from the Medical Outcomes Study. JAMA, 262(7), 907–913.

Stewart, A. L., Hays, R. D., & Ware, J. E., Jr. (1988). The MOS short-form general health survey. Reliability and validity in a patient population. Medical Care,26(7), 724–735.CrossRef

Stewart, J. W., McGrath, P. J., & Quitkin, F. M. (1992). Can mildly depressed outpatients with atypical depression benefit from antidepressants? American Journal of Psychiatry,149(5), 615–619. https://doi.org/10.1176/ajp.149.5.615.CrossRefPubMed

Stone, A. A., Bachrach, C. A., Jobe, J. B., Kurtzman, H. S., & Cain, V. S. (2000). The scient of self-report: Implications for research and practice (1st ed.). Mahwah, NJ: Lawrence Erlbaum Associates Inc.

Tedlow, J. R., Maurizio, F., Uebelacker, L. A., Alpert, J. E., Nierenberg, A. A., & Rosenbaum, J. F. (1996). Are study dropouts different from completers? Biological Psychiatry,40(7), 668–670. https://doi.org/10.1016/0006-3223(96)00204-1.CrossRefPubMed

Thompson, C., Peveler, R. C., Stephenson, D., & McKendrick, J. (2000). Compliance with antidepressant medication in the treatment of major depressive disorder in primary care: A randomized comparison of fluoxetine and a tricyclic antidepressant. American Journal of Psychiatry,157(3), 338–343. https://doi.org/10.1176/appi.ajp.157.3.338.CrossRefPubMed

Voils, C. I., Steffens, D. C., Flint, E. P., & Bosworth, H. B. (2005). Social support and locus of control as predictors of adherence to antidepressant medication in an elderly population. The American Journal of Geriatric Psychiatry,13(2), 157–165. https://doi.org/10.1176/appi.ajgp.13.2.157.CrossRefPubMed

Wells, K. B., Stewart, A., Hays, R. D., Burnam, M. A., Rogers, W., Daniels, M., …, Ware, J. (1989). The functioning and well-being of depressed patients. Results from the Medical Outcomes Study. JAMA, 262(7), 914–919.

World Health Oraganization. (2019). Social determinants of health. Retrieved May 15, 2019, from https://www.who.int/social_determinants/sdh_definition/en/.

Yoshikawa, H., Aber, J. L., & Beardslee, W. R. (2012). The effects of poverty on the mental, emotional, and behavioral health of children and youth: Implications for prevention. American Psychologist,67(4), 272–284. https://doi.org/10.1037/a0028015.CrossRefPubMed

Titel: Adherence to Antidepressants in Underserved Communities: A Comparison of Electronic Monitoring and Self-report Measures
verfasst von: Heather F. McClintock
Angela N. BeKampis
Erica Hartmann
Hillary R. Bogner
Publikationsdatum: 01.01.2020
Verlag: Springer US
Erschienen in: Community Mental Health Journal / Ausgabe 4/2020
Print ISSN: 0010-3853
Elektronische ISSN: 1573-2789
DOI: https://doi.org/10.1007/s10597-019-00533-2

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Adherence to Antidepressants in Underserved Communities: A Comparison of Electronic Monitoring and Self-report Measures

Abstract

Neu im Fachgebiet Psychiatrie

Demenzkranke durch Antipsychotika vielfach gefährdet

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

„Psychotherapie ist auch bei sehr alten Menschen hochwirksam!“

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

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