Skip to main content
Erschienen in: Journal of Anesthesia 6/2019

24.09.2019 | Original Article

Admission to the surgical intensive care unit during intensivist coverage is associated with lower incidence of postoperative acute kidney injury and shorter ventilator time

verfasst von: Tak Kyu Oh, In-Ae Song, Young-Tae Jeon

Erschienen in: Journal of Anesthesia | Ausgabe 6/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

This study aimed to assess the impact of intensivist coverage on the incidence of acute kidney injury (AKI) and ventilator time among patients postoperatively admitted to the intensive care unit (ICU).

Methods

Adult patients postoperatively admitted to the ICU between January 2012 and December 2017 were retrospectively enrolled. The incidence of AKI within 72 h of surgery and the postoperative ventilator time were compared between the groups covered by intensivists and non-intensivists.

Results

After propensity score (PS) matching, 5650 patients were included in the final analysis (2825 patients in each group). The incidence rate of AKI was significantly higher in the non-intensivist coverage group than in the intensivist coverage group (22.7% vs. 20.2%; P = 0.023). Moreover, logistic regression analysis in the PS-matched cohort showed that the incidence of postoperative AKI in the non-intensivist coverage group increased by 16% compared to that in the intensivist coverage group (odds ratio 1.16, 95% confidence interval 1.02–1.32; P = 0.023). Additionally, the median time of ventilator use in the non-intensivist coverage group was significantly longer than that in the intensivist coverage group [7.8 (interquartile range, IQR 2.6–13.8) h vs. 5.3 (1.8–8.3) h; P < 0.001].

Conclusion

High-intensity intensivist coverage is associated with a lower risk of postoperative AKI and shorter postoperative ventilator times. These findings suggested that in addition to medical trainees, initial management of surgical ICU patients by intensivists may lower the risk of AKI and facilitate early weaning from mechanical ventilation.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Besso J, Bhagwanjee S, Takezawa J, Prayag S, Moreno R. A global view of education and training in critical care medicine. Crit Care Clin. 2006;22(3):539–46 (x–xi).CrossRef Besso J, Bhagwanjee S, Takezawa J, Prayag S, Moreno R. A global view of education and training in critical care medicine. Crit Care Clin. 2006;22(3):539–46 (x–xi).CrossRef
2.
Zurück zum Zitat Wilcox ME, Chong CA, Niven DJ, Rubenfeld GD, Rowan KM, Wunsch H, Fan E. Do intensivist staffing patterns influence hospital mortality following ICU admission? A systematic review and meta-analyses. Crit Care Med. 2013;41(10):2253–74.CrossRef Wilcox ME, Chong CA, Niven DJ, Rubenfeld GD, Rowan KM, Wunsch H, Fan E. Do intensivist staffing patterns influence hospital mortality following ICU admission? A systematic review and meta-analyses. Crit Care Med. 2013;41(10):2253–74.CrossRef
3.
Zurück zum Zitat Pronovost PJ, Angus DC, Dorman T, Robinson KA, Dremsizov TT, Young TL. Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review. JAMA. 2002;288(17):2151–62.CrossRef Pronovost PJ, Angus DC, Dorman T, Robinson KA, Dremsizov TT, Young TL. Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review. JAMA. 2002;288(17):2151–62.CrossRef
4.
Zurück zum Zitat Kerlin MP, Adhikari NK, Rose L, Wilcox ME, Bellamy CJ, Costa DK, Gershengorn HB, Halpern SD, Kahn JM, Lane-Fall MB, Wallace DJ, Weiss CH, Wunsch H, Cooke CR, ATS Ad Hoc Committee on ICU Organization. An Official American Thoracic Society systematic review: the effect of nighttime intensivist staffing on mortality and length of stay among intensive care unit patients. Am J Respir Crit Care Med. 2017;195(3):383–93.PubMed Kerlin MP, Adhikari NK, Rose L, Wilcox ME, Bellamy CJ, Costa DK, Gershengorn HB, Halpern SD, Kahn JM, Lane-Fall MB, Wallace DJ, Weiss CH, Wunsch H, Cooke CR, ATS Ad Hoc Committee on ICU Organization. An Official American Thoracic Society systematic review: the effect of nighttime intensivist staffing on mortality and length of stay among intensive care unit patients. Am J Respir Crit Care Med. 2017;195(3):383–93.PubMed
5.
Zurück zum Zitat Kerlin MP. 24-Hour intensivist staffing is not beneficial for patients. Crit Care Med. 2018;46(1):152–4.CrossRef Kerlin MP. 24-Hour intensivist staffing is not beneficial for patients. Crit Care Med. 2018;46(1):152–4.CrossRef
6.
Zurück zum Zitat Wallace DJ, Angus DC, Barnato AE, Kramer AA, Kahn JM. Nighttime intensivist staffing and mortality among critically ill patients. N Engl J Med. 2012;366(22):2093–101.CrossRef Wallace DJ, Angus DC, Barnato AE, Kramer AA, Kahn JM. Nighttime intensivist staffing and mortality among critically ill patients. N Engl J Med. 2012;366(22):2093–101.CrossRef
7.
Zurück zum Zitat Weiser TG, Haynes AB, Molina G, Lipsitz SR, Esquivel MM, Uribe-Leitz T, Fu R, Azad T, Chao TE, Berry WR, Gawande AA. Estimate of the global volume of surgery in 2012: an assessment supporting improved health outcomes. Lancet. 2015;385(Suppl 2):S11.CrossRef Weiser TG, Haynes AB, Molina G, Lipsitz SR, Esquivel MM, Uribe-Leitz T, Fu R, Azad T, Chao TE, Berry WR, Gawande AA. Estimate of the global volume of surgery in 2012: an assessment supporting improved health outcomes. Lancet. 2015;385(Suppl 2):S11.CrossRef
8.
Zurück zum Zitat Jerath A, Laupacis A, Austin PC, Wunsch H, Wijeysundera DN. Intensive care utilization following major noncardiac surgical procedures in Ontario, Canada: a population-based study. Intensive Care Med. 2018;44(9):1427–35.CrossRef Jerath A, Laupacis A, Austin PC, Wunsch H, Wijeysundera DN. Intensive care utilization following major noncardiac surgical procedures in Ontario, Canada: a population-based study. Intensive Care Med. 2018;44(9):1427–35.CrossRef
9.
Zurück zum Zitat Tak Kyu O, Ji E, Ahn S, Kim DJ, Song IA. Admission to surgical intensive care unit in time with intensivist coverage and its association with postoperative 30-day mortality: the role of intensivists in a surgical intensive care unit. Anaesth Crit Care Pain Med. 2019;38(3):259–63.CrossRef Tak Kyu O, Ji E, Ahn S, Kim DJ, Song IA. Admission to surgical intensive care unit in time with intensivist coverage and its association with postoperative 30-day mortality: the role of intensivists in a surgical intensive care unit. Anaesth Crit Care Pain Med. 2019;38(3):259–63.CrossRef
10.
Zurück zum Zitat Abelha FJ, Botelho M, Fernandes V, Barros H. Determinants of postoperative acute kidney injury. Crit Care. 2009;13(3):R79.CrossRef Abelha FJ, Botelho M, Fernandes V, Barros H. Determinants of postoperative acute kidney injury. Crit Care. 2009;13(3):R79.CrossRef
11.
Zurück zum Zitat Jung YT, Kim MJ, Lee JG, Lee SH. Predictors of early weaning failure from mechanical ventilation in critically ill patients after emergency gastrointestinal surgery: a retrospective study. Medicine (Baltimore). 2018;97(40):e12741.CrossRef Jung YT, Kim MJ, Lee JG, Lee SH. Predictors of early weaning failure from mechanical ventilation in critically ill patients after emergency gastrointestinal surgery: a retrospective study. Medicine (Baltimore). 2018;97(40):e12741.CrossRef
12.
Zurück zum Zitat Yoo S, Lee KH, Lee HJ, Ha K, Lim C, Chin HJ, Yun J, Cho EY, Chung E, Baek RM, Chung CY, Wee WR, Lee CH, Lee HS, Byeon NS, Hwang H. Seoul National University Bundang Hospital's electronic system for total care. Healthc Inform Res. 2012;18(2):145–52.CrossRef Yoo S, Lee KH, Lee HJ, Ha K, Lim C, Chin HJ, Yun J, Cho EY, Chung E, Baek RM, Chung CY, Wee WR, Lee CH, Lee HS, Byeon NS, Hwang H. Seoul National University Bundang Hospital's electronic system for total care. Healthc Inform Res. 2012;18(2):145–52.CrossRef
13.
Zurück zum Zitat Kellum JA, Lameire N, Group KAGW. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (part 1). Crit Care. 2013;17(1):204.CrossRef Kellum JA, Lameire N, Group KAGW. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (part 1). Crit Care. 2013;17(1):204.CrossRef
14.
Zurück zum Zitat Hallan S, Asberg A, Lindberg M, Johnsen H. Validation of the modification of diet in renal disease formula for estimating GFR with special emphasis on calibration of the serum creatinine assay. Am J Kidney Dis. 2004;44(1):84–93.CrossRef Hallan S, Asberg A, Lindberg M, Johnsen H. Validation of the modification of diet in renal disease formula for estimating GFR with special emphasis on calibration of the serum creatinine assay. Am J Kidney Dis. 2004;44(1):84–93.CrossRef
15.
Zurück zum Zitat Wesselink EM, Kappen TH, Torn HM, Slooter AJC, van Klei WA. Intraoperative hypotension and the risk of postoperative adverse outcomes: a systematic review. Br J Anaesth. 2018;121(4):706–21.CrossRef Wesselink EM, Kappen TH, Torn HM, Slooter AJC, van Klei WA. Intraoperative hypotension and the risk of postoperative adverse outcomes: a systematic review. Br J Anaesth. 2018;121(4):706–21.CrossRef
16.
Zurück zum Zitat Rosenbaum PR, Rubin DB. Reducing bias in observational studies using subclassification on the propensity score. J Am Stat Assoc. 1984;79(387):516–24.CrossRef Rosenbaum PR, Rubin DB. Reducing bias in observational studies using subclassification on the propensity score. J Am Stat Assoc. 1984;79(387):516–24.CrossRef
17.
Zurück zum Zitat O'Neal JB, Shaw AD, Billings FT. Acute kidney injury following cardiac surgery: current understanding and future directions. Crit Care. 2016;20(1):187.CrossRef O'Neal JB, Shaw AD, Billings FT. Acute kidney injury following cardiac surgery: current understanding and future directions. Crit Care. 2016;20(1):187.CrossRef
18.
Zurück zum Zitat Hobson C, Ruchi R, Bihorac A. Perioperative acute kidney injury: risk factors and predictive strategies. Crit Care Clin. 2017;33(2):379–96.CrossRef Hobson C, Ruchi R, Bihorac A. Perioperative acute kidney injury: risk factors and predictive strategies. Crit Care Clin. 2017;33(2):379–96.CrossRef
20.
Zurück zum Zitat Veasey S, Rosen R, Barzansky B, Rosen I, Owens J. Sleep loss and fatigue in residency training: a reappraisal. JAMA. 2002;288(9):1116–24.CrossRef Veasey S, Rosen R, Barzansky B, Rosen I, Owens J. Sleep loss and fatigue in residency training: a reappraisal. JAMA. 2002;288(9):1116–24.CrossRef
21.
Zurück zum Zitat Grissinger M. An exhausted workforce increases the risk of errors. Pharm Ther. 2009;34(3):120–3. Grissinger M. An exhausted workforce increases the risk of errors. Pharm Ther. 2009;34(3):120–3.
22.
Zurück zum Zitat Perren A, Brochard L. Managing the apparent and hidden difficulties of weaning from mechanical ventilation. Intensive Care Med. 2013;39(11):1885–95.CrossRef Perren A, Brochard L. Managing the apparent and hidden difficulties of weaning from mechanical ventilation. Intensive Care Med. 2013;39(11):1885–95.CrossRef
23.
Zurück zum Zitat Totonchi Z, Baazm F, Chitsazan M, Seifi S, Chitsazan M. Predictors of prolonged mechanical ventilation after open heart surgery. J Cardiovasc Thorac Res. 2014;6(4):211–6.CrossRef Totonchi Z, Baazm F, Chitsazan M, Seifi S, Chitsazan M. Predictors of prolonged mechanical ventilation after open heart surgery. J Cardiovasc Thorac Res. 2014;6(4):211–6.CrossRef
24.
Zurück zum Zitat Kulkarni AP, Agarwal V. Extubation failure in intensive care unit: predictors and management. Indian J Crit Care Med. 2008;12(1):1–9.CrossRef Kulkarni AP, Agarwal V. Extubation failure in intensive care unit: predictors and management. Indian J Crit Care Med. 2008;12(1):1–9.CrossRef
Metadaten
Titel
Admission to the surgical intensive care unit during intensivist coverage is associated with lower incidence of postoperative acute kidney injury and shorter ventilator time
verfasst von
Tak Kyu Oh
In-Ae Song
Young-Tae Jeon
Publikationsdatum
24.09.2019
Verlag
Springer Singapore
Erschienen in
Journal of Anesthesia / Ausgabe 6/2019
Print ISSN: 0913-8668
Elektronische ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-019-02684-8

Weitere Artikel der Ausgabe 6/2019

Journal of Anesthesia 6/2019 Zur Ausgabe

Letter to the Editor

Reply to the editor

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.