Skip to main content
Erschienen in:

16.04.2020 | Editorial (by Invitation)

Adult spine deformity surgery—what do we miss?

verfasst von: Vitor Castro, Manuel Cunha e Sá

Erschienen in: Acta Neurochirurgica | Ausgabe 6/2020

Einloggen, um Zugang zu erhalten

Auszug

Despite the extraordinary advances in the last decades, adult spinal deformity (ASD) remains to this day one of the most formidable challenges presenting to spine surgeons. We have managed to improve by orders of magnitude our understanding of the biomechanical and pathophysiological principles on the basis of the disease, our diagnostic tools, the knowledge of the personal and socio-economic burden, and, more decisively, the surgical armamentarium available [8]. Though it is clear that we have come a long way since the Harrington rod, it is also undeniable that we often ended up less impressed by the results of surgery or overwhelmed by the complications it entails for a particularly frail patient group. In that sense, following the enthusiasm brought in by minimally invasive surgery (MIS) and techniques to the treatment of other spinal pathologies, the next obvious step was to try and adapt them to the treatment of degenerative adult deformity. The appeal was obvious: to minimize the aggressiveness of surgery and therefore costs/complications, while at least maintaining the same efficacy. This has been extensively studied, including comparative studies on the advantages and pitfalls of MIS vs open surgery [9], and MIS techniques have been progressively integrated in the rationale of surgical treatment [5]. However, very few studies have been published with follow-up greater than 2 years [1, 2], so long-term outcomes have been severely lacking. …
Literatur
1.
Zurück zum Zitat Anand N, Cohen JE, Cohen RB, Khandehroo B, Kahwaty S, Baron E (2017) Comparison of a newer versus older protocol for circumferential minimally invasive surgical (CMIS) correction of adult spinal deformity (ASD)-evolution over a 10-year experience. Spine Deform 5:213–223CrossRef Anand N, Cohen JE, Cohen RB, Khandehroo B, Kahwaty S, Baron E (2017) Comparison of a newer versus older protocol for circumferential minimally invasive surgical (CMIS) correction of adult spinal deformity (ASD)-evolution over a 10-year experience. Spine Deform 5:213–223CrossRef
2.
Zurück zum Zitat Bridwell KH, Baldus C, Berven S, Edwards C, Glassman S, Hamill C, Horton W, Lenke LG, Ondra S, Schwab F, Shaffrey C, Wootten D (2010) Changes in radiographic and clinical outcomes with primary treatment adult spinal deformity surgeries from two years to three- to five-years follow-up. Spine 35:1849–1854CrossRef Bridwell KH, Baldus C, Berven S, Edwards C, Glassman S, Hamill C, Horton W, Lenke LG, Ondra S, Schwab F, Shaffrey C, Wootten D (2010) Changes in radiographic and clinical outcomes with primary treatment adult spinal deformity surgeries from two years to three- to five-years follow-up. Spine 35:1849–1854CrossRef
3.
Zurück zum Zitat Chen YC, Huang WC, Chang HK, Lirng JF, Wu JC (2019) Long term outcomes and effects of surgery on degenerative spinal deformity: a 14-year national cohort study. J Clin Med 8(4):483CrossRef Chen YC, Huang WC, Chang HK, Lirng JF, Wu JC (2019) Long term outcomes and effects of surgery on degenerative spinal deformity: a 14-year national cohort study. J Clin Med 8(4):483CrossRef
4.
Zurück zum Zitat McCarthy I, O'Brien M, Ames CP, Robinson C, Errico T, Polly DW, Hostin R (2014) Incremental cost-effectiveness of adult spinal deformity surgery: observed quality-adjusted life years with surgery compared with predicted quality-adjusted life years without surgery. Neurosurg Focus 36(5):E3CrossRef McCarthy I, O'Brien M, Ames CP, Robinson C, Errico T, Polly DW, Hostin R (2014) Incremental cost-effectiveness of adult spinal deformity surgery: observed quality-adjusted life years with surgery compared with predicted quality-adjusted life years without surgery. Neurosurg Focus 36(5):E3CrossRef
5.
Zurück zum Zitat Mummaneni PV, Park P, Shaffrey CI, Wang MY, Uribe JS, Fessler RG, Chou D, Kanter AS, Okonkwo DO, Mundis GM, Eastlack RK, Nunley PD, Anand N, Virk MS, Lenke LG, Than KD, Robinson LC, Fu KM (2019) The MISDEF2 algorithm: an updated algorithm for patient selection in minimally invasive deformity surgery. J Neurosurg Spine 32:1–8 Mummaneni PV, Park P, Shaffrey CI, Wang MY, Uribe JS, Fessler RG, Chou D, Kanter AS, Okonkwo DO, Mundis GM, Eastlack RK, Nunley PD, Anand N, Virk MS, Lenke LG, Than KD, Robinson LC, Fu KM (2019) The MISDEF2 algorithm: an updated algorithm for patient selection in minimally invasive deformity surgery. J Neurosurg Spine 32:1–8
6.
Zurück zum Zitat Park P, Wang MY, Lafage V, Nguyen S, Ziewacz J, Okonkwo DO, Uribe JS, Eastlack RK, Anand N, Haque R, Fessler RG, Kanter AS, Deviren V, La Marca F, Smith JS, Shaffrey CI, Mundis GM, Mummaneni PV (2015) Comparison of two minimally invasive surgery strategies to treat adult spinal deformity. J Neurosurg Spine 22(4):374–380CrossRef Park P, Wang MY, Lafage V, Nguyen S, Ziewacz J, Okonkwo DO, Uribe JS, Eastlack RK, Anand N, Haque R, Fessler RG, Kanter AS, Deviren V, La Marca F, Smith JS, Shaffrey CI, Mundis GM, Mummaneni PV (2015) Comparison of two minimally invasive surgery strategies to treat adult spinal deformity. J Neurosurg Spine 22(4):374–380CrossRef
7.
Zurück zum Zitat Smith JS, Shaffrey CI, Lafage V, Schwab F, Scheer JK, Protopsaltis T, Klineberg E, Gupta M, Hostin R, Fu KG, Mundis GM, Kim H, Deviren V, SoroceanuA HRA, Burton DC, Bess S, Ames CP (2015) Comparison of best versus worst clinical outcomes for adult spinal deformity surgery: a retrospective review of a prospectively collected, multicenter database with 2-year follow-up. J Neurosurg Spine 23(3):349–359CrossRef Smith JS, Shaffrey CI, Lafage V, Schwab F, Scheer JK, Protopsaltis T, Klineberg E, Gupta M, Hostin R, Fu KG, Mundis GM, Kim H, Deviren V, SoroceanuA HRA, Burton DC, Bess S, Ames CP (2015) Comparison of best versus worst clinical outcomes for adult spinal deformity surgery: a retrospective review of a prospectively collected, multicenter database with 2-year follow-up. J Neurosurg Spine 23(3):349–359CrossRef
8.
Zurück zum Zitat Smith JS, Shaffrey CI, Ames CP, Lenke LG (2019) Treatment of adult thoracolumbar spinal deformity: past, present, and future. J Neurosurg Spine 30(5):551–567CrossRef Smith JS, Shaffrey CI, Ames CP, Lenke LG (2019) Treatment of adult thoracolumbar spinal deformity: past, present, and future. J Neurosurg Spine 30(5):551–567CrossRef
9.
Zurück zum Zitat Uribe JS, Deukmedjian AR, Mummaneni PV, Fu KG, Mundis GM, Okonkwo DO, Kanter AS, Eastlack R, Wang MY, Anand N, Fessler RG, La Marca F, Park P, Lafage V, Deviren V, Bess S, Shaffrey CI (2014) Complications in adult spinal deformity surgery: an analysis of minimally invasive, hybrid, and open surgical techniques. Neurosurg Focus 36(5):E15CrossRef Uribe JS, Deukmedjian AR, Mummaneni PV, Fu KG, Mundis GM, Okonkwo DO, Kanter AS, Eastlack R, Wang MY, Anand N, Fessler RG, La Marca F, Park P, Lafage V, Deviren V, Bess S, Shaffrey CI (2014) Complications in adult spinal deformity surgery: an analysis of minimally invasive, hybrid, and open surgical techniques. Neurosurg Focus 36(5):E15CrossRef
10.
Zurück zum Zitat Wang MY, Tran S, BruskoG ER, Park P, Nunley PD, Kanter AS, Uribe JS, Anand N, Okonkwo DO, Than KD, Shaffrey CI, Lafage V, Mundis GM, Mummaneni PV (2019) Less invasive spinal deformity surgery: the impact of the learning curve at tertiary spine care centers. J Neurosurg Spine 31(6):865–872CrossRef Wang MY, Tran S, BruskoG ER, Park P, Nunley PD, Kanter AS, Uribe JS, Anand N, Okonkwo DO, Than KD, Shaffrey CI, Lafage V, Mundis GM, Mummaneni PV (2019) Less invasive spinal deformity surgery: the impact of the learning curve at tertiary spine care centers. J Neurosurg Spine 31(6):865–872CrossRef
11.
Zurück zum Zitat Wang MY, Uribe J, Mummaneni PV, Tran S, Brusko GD, Park P, Nunley P, Kanter A, Okonkwo D, Anand N, Chou D, Shaffrey CI, Fu KM, Mundis Jr GM, Eastlack, R (2020) Minimally invasive spinal deformity surgery: an analysis of patients that fail to reach minimal clinically important difference (MCID). World Neurosurg Feb 20 Wang MY, Uribe J, Mummaneni PV, Tran S, Brusko GD, Park P, Nunley P, Kanter A, Okonkwo D, Anand N, Chou D, Shaffrey CI, Fu KM, Mundis Jr GM, Eastlack, R (2020) Minimally invasive spinal deformity surgery: an analysis of patients that fail to reach minimal clinically important difference (MCID). World Neurosurg Feb 20
Metadaten
Titel
Adult spine deformity surgery—what do we miss?
verfasst von
Vitor Castro
Manuel Cunha e Sá
Publikationsdatum
16.04.2020
Verlag
Springer Vienna
Erschienen in
Acta Neurochirurgica / Ausgabe 6/2020
Print ISSN: 0001-6268
Elektronische ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-020-04321-w

Kompaktes Leitlinien-Wissen Neurologie (Link öffnet in neuem Fenster)

Mit medbee Pocketcards schnell und sicher entscheiden.
Leitlinien-Wissen kostenlos und immer griffbereit auf ihrem Desktop, Handy oder Tablet.

Neu im Fachgebiet Neurologie

Belastungs-Malaise erschwert Reha bei Long-COVID

Um Menschen mit Langzeitfolgen von COVID-19 wirksam zu rehabilitieren, ist eine etwaige Post-Exertional Malaise unbedingt mitzuberücksichtigen, und das Trainingsprogramm entsprechend anzupassen.

Neuartige Antikörpertherapie bremst MS über zwei Jahre hinweg

Eine Therapie mit dem C40-Ligand-Blocker Frexalimab kann MS-Schübe und neue MRT-Läsionen über zwei Jahre hinweg verhindern. Dafür spricht die Auswertung einer offen fortgeführten Phase-2-Studie.

Therapiestopp bei älteren MS-Kranken kann sich lohnen

Eine Analyse aus Kanada bestätigt: Setzen ältere MS-Kranke die Behandlung mit Basistherapeutika ab, müssen sie kaum mit neuen Schüben und MRT-Auffälligkeiten rechnen.

Positive Phase IIb-Studie zu spezifischer CAR-T-Zell-Therapie bei Myasthenia gravis

Eine auf das B-Zell-Reifungsantigen gerichtete mRNA-basierte CAR-T-Zell-Therapie wurde jetzt in einer ersten Phase IIb-Studie zur Behandlung der generalisierten Myasthenia gravis mit Placebo verglichen.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.