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Cancer and Metastasis Reviews

Erschienen in:

21.11.2016

Advances in decoding breast cancer brain metastasis

verfasst von: Chenyu Zhang, Dihua Yu

Erschienen in: Cancer and Metastasis Reviews | Ausgabe 4/2016

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Abstract

The past decade has witnessed impressive advances in cancer treatment ushered in by targeted and immunotherapies. However, with significantly prolonged survival, upon recurrence, more patients become inflicted by brain metastasis, which is mostly refractory to all currently available therapeutic regimens. Historically, brain metastasis is an understudied area in cancer research, partly due to the dearth of appropriate experimental models that closely simulate the special biological features of metastasis in the unique brain environment and to the sophistication of techniques required to perform in-depth studies of the extremely complex and challenging brain metastasis. Yet, with increasing clinical demand for more effective treatment options, brain metastasis research has rapidly advanced in recent years. The present review spotlights the recent major progresses in basic and translational studies of brain metastasis with focuses on new animal models, novel imaging technologies, omics “big data” resources, and some new and exciting biological insights on brain metastasis.

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Titel: Advances in decoding breast cancer brain metastasis
verfasst von: Chenyu Zhang
Dihua Yu
Publikationsdatum: 21.11.2016
Verlag: Springer US
Erschienen in: Cancer and Metastasis Reviews / Ausgabe 4/2016
Print ISSN: 0167-7659
Elektronische ISSN: 1573-7233
DOI: https://doi.org/10.1007/s10555-016-9638-9

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Advances in decoding breast cancer brain metastasis

Abstract

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Prostatakarzinom: EU initiiert neues Screeningkonzept

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Stereotaktische Radiatio schlägt konventionelle Bestrahlung

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

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