Ausgabe 1/2022
Inhalt (49 Artikel)
Musculoskeletal ultrasound as a screening-tool for rheumatoid arthritis: results of the “Rheuma-Truck” screening and awareness initiative
- Open Access
- Research
Alexander Lautwein, Benedikt Ostendorf, Stefan Vordenbäumen, Aiko Liedmann, Ralph Brinks, Mario Giulini, Sarah Ohrndorf, Marina Backhaus, Hasan Acar, Oliver Sander, Jutta G. Richter, Matthias Schneider, Philipp Sewerin
Proteinuria and serum creatinine after 12 months of treatment for lupus nephritis as predictors of long-term renal outcome: a case–control study
- Open Access
- Research
Fernanda Nogueira Holanda Ferreira Braga, Marta Maria das Chagas Medeiros, Antonio Brazil Viana Junior, Matheus Eugênio de Sousa Lima, Levi Coelho Maia Barros, Marcelo Ximenes Pontes, Allysson Wosley de Sousa Lima, Paula Frassinetti Castelo Branco Camurça Fernandes
Guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force
- Open Access
- Position article and guidelines
Anna Carolina Faria Moreira Gomes Tavares, Ana Karla Guedes de Melo, Vítor Alves Cruz, Viviane Angelina de Souza, Joana Starling de Carvalho, Ketty Lysie Libardi Lira Machado, Lilian David de Azevedo Valadares, Edgard Torres dos Reis Neto, Rodrigo Poubel Vieira de Rezende, Maria Fernanda Brandão de Resende Guimarães, Gilda Aparecida Ferreira, Alessandra de Sousa Braz, Rejane Maria Rodrigues de Abreu Vieira, Marcelo de Medeiros Pinheiro, Sandra Lúcia Euzébio Ribeiro, Blanca Elena Gomes Rios Bica, Kátia Lino Baptista, Izaias Pereira da Costa, Claudia Diniz Lopes Marques, Maria Lúcia Lemos Lopes, José Eduardo Martinez, Rina Dalva Neubarth Giorgi, Lícia Maria Henrique da Mota, Marcos Antônio Araújo da Rocha Loures, Eduardo dos Santos Paiva, Odirlei André Monticielo, Ricardo Machado Xavier, Adriana Maria Kakehasi, Gecilmara Cristina Salviato Pileggi
Statin indication according to the 2019 World Health Organization cardiovascular disease risk charts and carotid ultrasound in Mexican mestizo rheumatoid arthritis patients
- Open Access
- Research
Dionicio A. Galarza-Delgado, Iris J. Colunga-Pedraza, Jose R. Azpiri-Lopez, Natalia Guajardo-Jauregui, Alejandra B. Rodriguez-Romero, Julieta Loya-Acosta, Alejandro Meza-Garza, Jesus A. Cardenas-de la Garza, Salvador Lugo-Perez, Jessica N. Castillo-Treviño
The effect of initiation of urate-lowering treatment during a gout flare on the current episode: a meta-analysis of randomized controlled trials
- Open Access
- Research
Ertao Jia, Xiaoling Yao, Hongling Geng, Li Zhong, Jingjing Xie, Yuya Xiao, Yubao Jiang, Xia Qiu, Min Xiao, Yanying Zhang, Dabin Tang, Jiaxin Wei, Jianyong Zhang
Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a Brazilian cohort
- Open Access
- Research
André Cavalcanti, Aline Islabão, Cristina Magalhães, Sarah Veloso, Marlon Lopes, Rogério do Prado, Bruna Aquilante, Ana Maria Terrazas, Maria Fernanda Rezende, Gleice Clemente, Maria Teresa Terreri
Official position of the Brazilian Association of Bone Assessment and Metabolism (ABRASSO) on the evaluation of body composition by densitometry: part I (technical aspects)—general concepts, indications, acquisition, and analysis
- Open Access
- Position article and guidelines
Sergio Setsuo Maeda, Barbara Santarosa Emo Peters, Lígia Araújo Martini, Hannah Karen Moreira Antunes, Maria Cristina Gonzalez, Henrique Pierotti Arantes, Carla M. Prado, Camila Lemos Pinto, Iana Mizumukai de Araújo, Francisco José Albuquerque de Paula, Joao Lindolfo Cunha Borges, Ben-Hur Albergaria, Marcela Ushida, Guilherme Cardenaz de Souza, Laura Maria Carvalho de Mendonça, Mirley do Prado, Marcelo de Medeiros Pinheiro
Correction to: 2021 recommendations of the Brazilian Society of Rheumatology for the gynecological and obstetric care of patients with Sjogren’s syndrome
- Open Access
- Correction
Fabiola Reis Oliveira, Valeria Valim, Sandra Gofnet Pasoto, Marilena Leal Mesquita Silvestre Fernandes, Maria Lucia Lemos Lopes, Sonia Cristina de Magalhães Souza Fialho, Aysa César Pinheiro, Laura Caldas dos Santos, Simone Appenzeller, Tania Fidelix, Sandra Lucia Euzébio Ribeiro, Danielle Christinne Soares Egypto de Brito, Tatiana Libório, Maria Carmen Lopes Ferreira Silva Santos, Leandro Tanure, Juliana DAgostino Gennari, Vinicius Tassoni Civile, Ana Carolina Pereira Nunes Pinto, César Ramos Rocha-Filho, Samira Tatiyama Miyamoto, Lissiane Karine Noronha Guedes, Alisson Pugliesi, Virginia Fernandes Moça Trevisani
Evaluation of peripheral neuropathy in lower limbs of patients with rheumatoid arthritis and its relation to fall risk
- Open Access
- Research
Fabio de Araújo Pereira, Mariana de Almeida Lourenço, Marcos Renato de Assis
Increased risk of mortality in systemic sclerosis-associated pulmonary hypertension: a systemic review and meta-analysis
- Open Access
- Research
Anji Xiong, Qingting Liu, Jiaxun Zhong, Yuzi Cao, Qilang Xiang, Ziyi Hu, Shifeng Zhou, Zhuoyao Song, Huini Chen, Yan Zhang, Hongxu Cui, Shiquan Shuai
Official Position of the Brazilian Association of Bone Assessment and Metabolism (ABRASSO) on the evaluation of body composition by densitometry—part II (clinical aspects): interpretation, reporting, and special situations
- Open Access
- Position article and guidelines
Sergio Setsuo Maeda, Ben-Hur Albergaria, Vera Lúcia Szejnfeld, Marise Lazaretti-Castro, Henrique Pierotti Arantes, Marcela Ushida, Diogo Souza Domiciano, Rosa Maria Rodrigues Pereira, Rosângela Villa Marin-Mio, Mônica Longo de Oliveira, Laura Maria Carvalho de Mendonça, Mirley do Prado, Guilherme Cardenaz de Souza, Cecília Zanin Palchetti, Roseli Oselka Saccardo Sarni, Maria Teresa Terreri, Luiz Claudio Gonçalves de Castro, Silvana Martinez Baraldi Artoni, Lizandra Amoroso, Débora Emy Karcher, Carla M. Prado, Maria Cristina Gonzalez, Marcelo de Medeiros Pinheiro
Dietetic intervention in psoriatic arthritis: the DIETA trial
- Open Access
- Research
Beatriz F. Leite, Melissa A. Morimoto, Carina M. F. Gomes, Barbara N. C. Klemz, Patrícia S. Genaro, Nittin Shivappa, James R. Hébert, Nágila R. T. Damasceno, Marcelo M. Pinheiro
Factors associated with hospitalizations for Covid-19 in patients with rheumatoid arthritis: data from the Reumacov Brazil registry
- Open Access
- Research
Ana Paula Monteiro Gomides, Cleandro Pires de Albuquerque, Licia Maria Henrique da Mota, Guilherme Devidé, Laiza Hombre Dias, Angela Luzia Branco Pinto Duarte, Raquel Altoé Giovelli, Thais Evelyn Karnopp, Hugo Deleon de Lima, Adriana Marinho, Marianne Schrader de Oliveira, Felipe Omura, Aline Ranzolin, Gustavo Resende, Francinne Machado Ribeiro, Sandra Lúcia Euzébio Ribeiro, Nathália de Carvalho Sacilotto, Wander Gonzaga dos Santos, Samuel Katsuyuki Shinjo, Samia Araujo de Sousa Studart, Flávia Patricia Sena Teixeira, Michel Alexandre Yazbek, Gilda Aparecida Ferreira, Odirlei A. Monticielo, Eduardo Paiva, Gecilmara Cristina Salviato Pileggi, Edgard Torres dos Reis-Neto, Marcelo de Medeiros Pinheiro, Claudia D. L. Marques
Psoriatic arthritis mutilans: a descriptive study from a Brazilian tertiary center
- Open Access
- Letter
Rafael Alves Cordeiro, Jobson Lopes de Oliveira, Percival Degrava Sampaio-Barros, Claudia Goldenstein-Schainberg
Reference range of serum uric acid and prevalence of hyperuricemia: a cross-sectional study from baseline data of ELSA-Brasil cohort
- Open Access
- Research
Murillo Dório, Isabela M. Benseñor, Paulo Lotufo, Itamar S. Santos, Ricardo Fuller
Effect of biological disease-modifying antirheumatic drugs on body composition in patients with rheumatoid arthritis: a systematic review and meta-analysis
- Open Access
- Research
Mariana Peixoto Guimarães Ubirajara e Silva de Souza, Nathalia Sernizon Guimarães, Maria Fernanda Brandão de Resende Guimarães, Viviane Angelina de Souza, Adriana Maria Kakehasi
Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis
- Open Access
- Research
Victor Z. Sun, Terry L. Melim, Soumya Mitra, Jamie E. Erickson, Shaughn H. Bryant, Avery Farnham, Susan Westmoreland, Heather Knight, Liang Zhang, Wendy Ritacco, Kristoff Homan, Lorenzo Benatuil, Annette J. Schwartz Sterman, Andrew D. Goodearl
Recommendations for evaluation and diagnosis of extra-glandular manifestations of primary sjogren syndrome: results of an epidemiologic systematic review/meta-analysis and a consensus guideline from the Brazilian Society of Rheumatology (articular, pulmonary and renal)
- Open Access
- Position article and guidelines
Virginia Fernandes Moça Trevisani, Alisson Pugliesi, Sandra Gofinet Pasoto, Maria Lucia Lemos Lopes, Lissiane Karine Noronha Guedes, Samira Tatiyama Miyamoto, Marilena Leal Mesquita Silvestre Fernandes, Sonia Cristina de Magalhães Souza Fialho, Aysa César Pinheiro, Laura Caldas dos Santos, Simone Appenzeller, Tania Fidelix, Sandra Lúcia Euzébio Ribeiro, Danielle Christinne Soares Egypto de Brito, Tatiana Nayara Libório-Kimura, Maria Carmen Lopes Ferreira Silva Santos, Diego Ustárroz Cantali, Juliana D’Agostino Gennari, Vinicius Tassoni Civile, Ana Carolina Pereira Nunes Pinto, César Ramos Rocha-Filho, Fabiola Reis Oliveira, Aline Pereira da Rocha, Valeria Valim
Primary Sjögren syndrome and development of another autoimmune rheumatic disease during the follow-up
- Open Access
- Research
María Florencia Rodríguez, Cecilia Asnal, Carla Andrea Gobbi, Antonio Carlos Catalán Pellet, Natalia Herscovich, Cristina Amitrano, Julia Demarchi, Damián Duartes Noé, Carolina Segura, Francisco Caeiro, Nadia Riscanevo, Verónica Saurit, Silvia Papasidero, Paula B. Alba, Laura Raiti, Vanesa Cruzat, María Lida Santiago, Sofía Vélez, Gabriela Salvatierra, Vicente Juárez, Anastasia Secco
Spotlight on latent tuberculosis infection screening for juvenile idiopathic arthritis in two countries, comparing high and low risk patients
- Open Access
- Research
Daniela Piotto, Aline Nicacio, Agna Neto, Ana Filipa Mourão, Filipa Oliveira-Ramos, Raquel Campanilho-Marques, Margarida Guedes, Marta Cabral, Maria José Santos, João Eurico Fonseca, Helena Canhão, Nádia Emi Aikawa, Sheila K. F. Oliveira, Virginia P. L. Ferriani, Gecilmara C. S. Pileggi, Claudia S. Magalhães, Clovis Artur Silva, Maria Teresa Terreri
Syndecan-4 is correlated with disease activity and serological characteristic of rheumatoid arthritis
- Open Access
- Research
Juan Zhao, Xia Ye, Zhuoli Zhang
Effects of medications on incidence and risk of knee and hip joint replacement in patients with osteoarthritis: a systematic review and meta-analysis
- Open Access
- Research
Beibei Cui, Yuehong Chen, Yunru Tian, Huan Liu, Yupeng Huang, Geng Yin, Qibing Xie
Clinical and laboratory evaluation of sicca complaints: distinctive aspects of primary, secondary and non-Sjogren syndrome
- Open Access
- Research
Fabíola Reis de Oliveira, Ana Carolina F. Motta, Carolina Maria Módulo, Denny Marcos Garcia, John A. Chiorini, Paulo Louzada-Junior, Eduardo Melani Rocha
The effect of systemic lupus erythematosus on sexual function in women: an updated meta-analysis based on cross-sectional studies
- Open Access
- Research
Maoyu Liu, Jianguo Dou, Qianqian Wang
PLCL1 regulates fibroblast-like synoviocytes inflammation via NLRP3 inflammasomes in rheumatoid arthritis
- Open Access
- Research
Shuai Luo, Xiao-Feng Li, Ying-Li Yang, Biao Song, Sha Wu, Xue-Ni Niu, Yuan-Yuan Wu, Wen Shi, Cheng Huang, Jun Li
Correction: The effect of systemic lupus erythematosus on sexual function in women: an updated meta-analysis based on cross-sectional studies
- Open Access
- Correction
Maoyu Liu, Jianguo Dou, Qianqian Wang
Vitamin D supplementation modulates autophagy in the pristane-induced lupus model
- Open Access
- Research
Manuela dos Santos, Jordana Miranda de Souza Silva, Bárbara Jonson Bartikoski, Eduarda Correa Freitas, Amanda Busatto, Rafaela Cavalheiro do Espírito Santo, Odirlei Andre Monticielo, Ricardo Machado Xavier
Does [18F]F-FDG-PET/MRI add metabolic information to magnetic resonance image in childhood-onset Takayasu’s arteritis patients? A multicenter case series
- Open Access
- Research
Gleice Clemente, Alexandre W. de Souza, Hilton Leão Filho, Fernando M. A. Coelho, Carlos Buchpiguel, Marcos Lima, Camila Carneiro, Rosa M. R. Pereira, Nadia Aikawa, Clovis A. Silva, Lucia M. A. Campos, Gabriel Alves, Camilla Astley, Bruno Gualano, Maria Teresa Terreri
Update to “guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force”
- Open Access
- Letter
Anna Carolina Faria Moreira Gomes Tavares, Ana Karla Guedes de Melo, Vítor Alves Cruz, Lilian David de Azevedo Valadares, Ricardo Machado Xavier, Viviane Angelina de Souza, Gecilmara Cristina Salviato Pileggi
Ultrasound joint examination by an automated system versus by a rheumatologist: from a patient perspective
- Open Access
- Research
Bill Aplin Frederiksen, Maja Schousboe, Lene Terslev, Nikolaj Iversen, Hanne Lindegaard, Thiusius Rajeeth Savarimuthu, Søren Andreas Just
Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain
- Open Access
- Research
João Marcos da Silva Carvalho, Eugênia Maria Teixeira de Araújo Campos, José Luiz Nunes Ferreira, Huliana Mourão Carvalho, José Abraão Carneiro Neto, Tássila de Oliveira Carneiro, Edgar Marcelino Carvalho
The influence of demography and referral medical specialty on the detection of autoantibodies to HEP-2 cells in a large sample of patients
- Open Access
- Research
Wilton Ferreira Silva Santos, Ana Paula de Castro Cantuária, Daniele de Castro Félix, Leandro Kegler Nardes, Igor Cabral Santos de Melo
Graft versus host disease-related eosinophilic fasciitis: cohort description and literature review
- Open Access
- Research
Cristina Hidalgo Calleja, Daniel Martín Hidalgo, Concepción Román Curto, Lourdes Vázquez López, Estefanía Pérez López, Mónica Cabrero Calvo, Ana África Martín López, María Dolores Caballero Barrigón, Lucía Lopez-Corral
VI Brazilian consensus guidelines for detection of anti-cell autoantibodies on HEp-2 cells
- Open Access
- Position article and guidelines
Wilson de Melo Cruvinel, Luis Eduardo Coelho Andrade, Alessandra Dellavance, Antônio Carlos Ximenes, Carlos David Araújo Bichara, Cristóvão Luis Pitangueira Mangueira, Eloísa Bonfá, Fabiano de Almeida Brito, Henrique Ataíde Mariz, Lisiane Maria Enriconi dos Anjos, Sandra Gofinet Pasoto, Valeria Valim, Wilton Ferreira Silva dos Santos, Clayson Moura Gomes, Roberpaulo Anacleto Neves, Paulo Luiz Carvalho Francescantonio
Recommendations for evaluation and diagnosis of extra-glandular manifestations of primary Sjögren syndrome: results of an epidemiologic systematic review/meta-analysis and a consensus guideline from the Brazilian society of rheumatology (hepatic, gastrointestinal and pancreatic)
- Open Access
- Position article and guidelines
Virginia Fernandes Moça Trevisani, Aysa César Pinheiro, Sonia Cristina de Magalhães Souza Fialho, Marilena Leal Mesquita Silvestre Fernandes, Alisson Pugliesi, Sandra Gofinet Pasoto, Maria Lucia Lemos Lopes, Lissiane Karine Noronha Guedes, Samira Tatiyama Miyamoto, Laura Caldas dos Santos, Simone Appenzeller, Tania Fidelix, Sandra Lúcia Euzébio Ribeiro, Danielle Christinne Soares Egypto de Brito, Tatiana Nayara Libório-Kimura, Maria Carmen Lopes Ferreira Silva Santos, Diego Ustárroz Cantali, Juliana D.’Agostino Gennari, Karina Gatz Capobianco, Vinicius Tassoni Civile, Ana Carolina Pereira Nunes Pinto, Aline Pereira da Rocha, César Ramos Rocha-Filho, Fabiola Reis Oliveira, Valeria Valim
“In Memoriam” – Rosa Maria Rodrigues Pereira (1958 – 2022)
- Open Access
- Obituary
Eloísa Bonfa, Percival Sampaio-Barros
Serum MMP-9, SP-D, and VEGF levels reflect the severity of connective tissue disease-associated interstitial lung diseases
- Open Access
- Research
Chengna Lv, Qipan Zhang, Pan Tang, Lun Guo, Qunli Ding
Maintained activity in ankylosing spondylitis patients treated with TNFi and/or NSAID for at least 12 weeks: a cross-sectional study in Brazil
- Open Access
- Research
Ricardo Acayaba de Toledo, Felipe Merchan Ferraz Grizzo, Vander Fernandes, Renato Calheiros, Ricardo T. Russo, Gustavo Rosal, Luiz Roberto Delboni Marchese, Roberto Tunala, Renato Watanabe, Marina Gabriela Birck, Guilherme Silva Julian, Francisco Jose Forestiero
Measurement properties of the Brazilian online version of the Fibromyalgia Rapid Screening Tool (FiRST)
- Open Access
- Research
Ana Paula de Sousa, Guilherme Tavares de Arruda, André Pontes-Silva, Marcelo Cardoso de Souza, Patricia Driusso, Mariana Arias Avila
Knee osteoarthritis pre-screening questionnaire (KOPS): cross-cultural adaptation and measurement properties of the brazilian version—KOPS Brazilian version
- Open Access
- Research
Francis Trombini-Souza, Ingrid Macedo, Flávia Yázigi, Diogo Veiga, Filomena Carnide, Margarida Espanha, George Oliveira, Claudia Goldenstein-Schainberg, Ricardo Fuller
Clinical manifestations, outcomes, and antibody profile of Brazilian adult patients with dermatomyositis: a single-center longitudinal study
- Open Access
- Research
Natássia Cristina Carboni Truzzi, Leonardo Santos Hoff, Isabela Bruna Pires Borges, Fernando Henrique Carlos de Souza, Samuel Katsuyuki Shinjo
Quantitative evaluation of very early cartilage damage in experimental osteoarthritis using scanning electron microscopy
- Open Access
- Research
Virgínia Cláudia Carneiro Girão-Carmona, Mirna Marques Bezerra, Fernanda Maria Aragão Ximenes Porto, Ana Carolina Matias Dinelly Pinto, Rodolfo de Melo Nunes, Anelise Maria Costa Vasconcelos Alves, Claudio Cabral Campello, Ana Caroline Rocha de Melo Leite, Gerly Anne de Castro Brito, Francisco Airton Castro da Rocha
Fasciola hepatica extract suppresses fibroblast-like synoviocytes in vitro and alleviates experimental arthritis
- Open Access
- Research
Suelen Pizzolatto Dalmolin, Renata Ternus Pedó, Thales Hein da Rosa, Jordana Miranda de Souza Silva, Mirian Farinon, Maria Luísa Gasparini, Eduardo Cremonese Filippi Chiela, Ana Helena Paz, Martín Pablo Cancela Sehabiague, Henrique Bunselmeyer Ferreira, Rafaela Cavalheiro do Espírito Santo, Fabiany da Costa Gonçalves, Ricardo Machado Xavier
Treatment with biological therapy is associated with faster recovery and lower frequency of treatment switch among rheumatic patients with Chikungunya fever
- Open Access
- Research
Aline Ranzolin, Claudia Diniz Lopes Marques, Laurindo Ferreira da Rocha Junior, Angela Luzia Branco Pinto Duarte, Hugo Deleon de Lima, Lays Miranda de Almeida Martins, Anderson Rodrigues de Almeida, Priscilla Stela Santana de Oliveira, Moacyr Jesus Barreto de Melo Rêgo, Maira Galdino da Rocha Pitta, Markus Bredemeier, Ieda Maria Magalhães Laurindo
COVID-19 was not associated or trigger disease activity in spondylarthritis patients: ReumaCoV-Brasil cross-sectional data
- Open Access
- Research
Claudia Diniz Lopes Marques, Sandra Lúcia Euzébio Ribeiro, Cleandro P. Albuquerque, Samia Araujo de Sousa Studart, Aline Ranzolin, Nicole Pamplona Bueno de Andrade, Andrea T. Dantas, Guilherme D. Mota, Gustavo G. Resende, Adriana O. Marinho, Danielle Angelieri, Danieli Andrade, Francinne M. Ribeiro, Felipe Omura, Nilzio A. Silva, Laurindo Rocha Junior, Danielle E. Brito, Diana C. Fernandino, Michel A. Yazbek, Mariana P. G. Souza, Antonio Carlos Ximenes, Ana Silvia S. Martins, Glaucio Ricardo W. Castro, Lívia C. Oliveira, Ana Beatriz S. B. Freitas, Adriana M. Kakehasi, Ana Paula M. Gomides, Edgard Torres Reis Neto, Gecilmara S. Pileggi, Gilda A. Ferreira, Licia Maria H. Mota, Ricardo M. Xavier, Marcelo de Medeiros Pinheiro
Cross-cultural and clinical validation of the MDHAQ/RAPID3 questionnaire in electronic format for a Brazilian population of patients with rheumatoid arthritis
- Open Access
- Research
Ilka Benedet Lineburger, Claiton Viegas Brenol, Alice Silveira Goularte, Edila Penna Pinheiro, Vânia Naomi Hirakata
Immunomodulatory effects of atorvastatin on MRL/lpr mice
- Open Access
- Research
Jing Sun, Weidong Xu, Zhiying Wu, Caijin Cao, Yane Tan, Meifang Zhu, Hongze Wu, Jianping Yu
CD19+CD24highCD27+ B cell and interleukin 35 as potential biomarkers of disease activity in systemic lupus erythematosus patients
- Open Access
- Research
Hui Xiong, Zengqi Tang, Ying Xu, Zhenrui Shi, Zhixuan Guo, Xiuting Liu, Guozhen Tan, Xuechen Ai, Qing Guo
The impact of normal serum complement levels on the disease classification and clinical characteristics in systemic lupus erythematosus
- Open Access
- Research
Ryota Takamatsu, Yasuhiro Shimojima, Dai Kishida, Takanori Ichikawa, Yoshiki Sekijima
