Ausgabe 9/2025
Inhalt (38 Artikel)
Integration of Generative AI with Human Expertise in HEOR: A Hybrid Intelligence Framework
- Open Access
- Practical Approach
Tushar Srivastava, Hanan Irfan, Vladimir Babiy, Shilpi Swami
Ethnicity Risk and Exertional Rhabdomyolysis: A Narrative Review
- Review
Angela Nguyen, Austin Thomassen, Ellie M. MacDonald, Victoria A. Rodriguez, John M. Brown, Sahar Shekoohi, Alan D. Kaye
Systematic Review and Meta-analysis of Long-Term Nusinersen Effectiveness in Adolescents and Adults with Spinal Muscular Atrophy
- Open Access
- Review
Tim Hagenacker, Angela D. Paradis, Katherine A. Lawson-Michod, Bora Youn
Trospium Chloride in the Treatment of Overactive Bladder Syndrome and Detrusor Overactivity
- Open Access
- Review
José C. Truzzi, Marair G. F. Sartori, Vitorio L. Kemp
Efficacy and Safety of TV-46000 and Second-Generation Long-Acting Injectable Antipsychotics for Schizophrenia: A Systematic Literature Review and Network Meta-Analysis of Randomized Controlled Trials
- Open Access
- Review
Kelli R. Franzenburg, Rolf Hansen, Mark Suett, Stephen F. Thompson, Martin Sergerie, David Garcia, Howard C. Margolese
Interferon in Liver Diseases: Recent Advances
- Open Access
- Review
Yuting Gao, Yuhang Yin, Pengpeng Xie, Deyu Zhang, Hongyu Li, Xingshun Qi
Real-World Evidence for Ixekizumab in the Treatment of Psoriasis, Psoriatic Arthritis, and Axial Spondyloarthritis: Systematic Literature Review 2022–2023
- Open Access
- Review
Luis Puig, Philipp Sewerin, Christopher Schuster, Khai Jing Ng, Manny Papadimitropoulos, Sneha Gadagamma, Mercedes Nuñez, Anastasia Lampropoulou
Obstructive Sleep Apnea: An Evolving Therapeutic Landscape with an Emerging Role for Incretin-Based Therapies
- Open Access
- Review
Bolong Xu, Kaveh Gaynor-Sodeifi, Vaishnavi Kundel
Key Learnings from Clinical Research and Real-World Evidence on Asfotase Alfa Effectiveness in Hypophosphatasia: 10 Years Post-Approval
- Open Access
- Review
Aliya A. Khan, Eric T. Rush, Craig Wakeford, Daniel Staub, Maria Luisa Brandi
Matching-Adjusted Indirect Comparison of Sotorasib Versus Adagrasib in Previously Treated Advanced/Metastatic Non-Small Cell Lung Cancer Harboring KRAS G12C Mutation
- Open Access
- Original Research
Divyan Chopra, Zhiyi Lan, David M. Waterhouse, Jürgen Wolf, Enriqueta Felip, Hoora Moradian, Nadia Karim, Cynthia Obiozor, Björn Stollenwerk
Epidemiology and Steroid Dependency Reduction in Crohn’s Disease During the Biologics Era: A Nationwide Population-Based Study
- Open Access
- Original Research
Nai-Yu Chen, Chiao-Hsiung Chuang, Yu-Ching Chang, Yea-Huei Kao Yang, Hua Hsu, Chieh-Min Chen, Ching-Lan Cheng
Safety, Tolerability, and Efficacy of Adjunctive Brivaracetam in Japanese and Chinese Patients with Focal-Onset Seizures: Interim Analysis of a Phase 3 Open-Label Extension Trial
- Open Access
- Original Research
Ayataka Fujimoto, Bing Qin, Dimitrios Bourikas, Najla Dickson, Brian Moseley, Tomonobu Sano, Tadaharu Soma, Weiwei Sun, Jun Watanabe, Dong Zhou, Yushi Inoue
Treatment Patterns and Healthcare Resource Utilization Following Initiation of Aripiprazole Lauroxil Using a 1-Day Initiation Regimen in Patients with Schizophrenia
- Open Access
- Original Research
John Lauriello, Michael J. Doane, James A. McGrory, Alejandro G. Hughes, Lauren N. Strand
How to ESCAPE from Pain? An Observational Study on Improving Pain and Quality of Life with the Cannamedical® Hybrid Cannabis Extract
- Open Access
- Original Research
Yvonne Wagner, Ines Samel, Kristina Probst, Lukas Schollenberger, Christian Ruckes, Joachim Nadstawek
Challenges and Opportunities for Improving Management of Patients with nAMD and DME in China: Insights from a Global Survey on Anti-VEGF Therapy
- Original Research
Xiaodong Sun, Yan Li, Zongming Song, Xiang Ma, Hong Yan, Shanshan Yu, Jingfa Zhang, Yanchun Wu, Zixu Huang, Haiyan Wang, Tao Bai, Jun Hu, Jing Tan, Xiaofeng Lin
Relationships Among Glaucoma, Cardiovascular Diseases, and Mortality
- Open Access
- Original Research
Luciano Quaranta, Alessia A. Galbussera, Mauro Tettamanti, Alessio Novella, Luca Pasina, Ida Fortino, Olivia Leoni, Francesco Oddone, Sara Giammaria, Mikołaj Kużniak, Robert N. Weinreb, Alessandro Nobili
Survival Outcomes with Cilta-cel Versus Conventional Treatment Regimens for Patients with Lenalidomide-Refractory Multiple Myeloma Using Inverse Probability of Treatment Weighting
- Open Access
- Original Research
Rafael Fonseca, Joris Diels, Francesca Ghilotti, João Mendes, Sandra Van Hoorenbeeck, Seina Lee, Jordan M. Schecter, Nikoletta Lendvai, Nitin Patel, Ana Triguero, Winfried Alsdorf, Niels W. C. J. van de Donk, Margherita Ursi
Comparative Effectiveness of FF/UMEC/VI and BUD/GLY/FORM in Patients with COPD Stepping Up From Dual Therapy
- Open Access
- Original Research
Jadwiga A. Wedzicha, Stephen G. Noorduyn, Valentina Di Boscio, Olivier Le Rouzic, Anurita Majumdar, Rosirene Paczkowski, Stephen Weng, Guillaume Germain, François Laliberté, David Mannino
Burden of Atopic Dermatitis in Patients Initiating Systemic Therapies in the United States
- Original Research
Matthew Zirwas, Nicole Princic, Megan K. Richards, Aamir Qureshi, Lorenzo Sabatelli, Peter Lio
Development of the Pediatric Weight Questionnaire (PWQ™) for Children and Adolescents with Obesity
- Open Access
- Original Research
Kristina S. Boye, Amy Clark, Chisom Kanu, Lisa M. Neff, Anne M. Skalicky
Real-World Safety and Effectiveness of Vadadustat in Patients with Chronic Kidney Disease-Related Anemia: Interim Analysis of Postmarketing Surveillance in Japan
- Open Access
- Original Research
Masaomi Nangaku, Kazuyo Sasaki, Jing Bi, Kiichiro Ueta, Kenichi Nishimura, Takafumi Hashimoto, Mihoko Hata
Broad Impact of Bowel Urgency in Ulcerative Colitis and Crohn’s Disease: US, European, and Japanese Patient and Healthcare Professional Perspectives from the Communicating Needs and Features of IBD Experiences (CONFIDE) Survey
- Open Access
- Original Research
David T. Rubin, Alison Potts Bleakman, Simon Travis, Marla Dubinsky, Stefan Schreiber, Remo Panaccione, Theresa Hunter Gibble, Cem Kayhan, Tommaso Panni, Eoin Flynn, Angelo D. Favia, Christian Atkinson, Sonal Saxena, Toshifumi Hibi
Patient-Reported Outcomes in Adults with Moderate-to-Severe Atopic Dermatitis Treated with Stapokibart over 52 weeks: A Post Hoc Analysis of a Phase 3 Trial
- Original Research
Yan Zhao, Litao Zhang, Liming Wu, Bin Yang, Jinyan Wang, Yumei Li, Qingchun Diao, Jingyi Li, Qing Sun, Xiaohong Zhu, Xiaoyong Man, Lihua Wang, Yanyan Feng, Tao Cai, Huiming Zeng, Linfeng Li, Jianyun Lu, Hong Ren, Fuqiu Li, Qianjin Lu, Xiaohua Tao, Rong Xiao, Chao Ji, Chao Liang, Yanping Qiu, Bo Chen, Jianzhong Zhang
Pharmacokinetics and Safety of Ripretinib in Participants with Hepatic Impairment: A Phase 1 Study
- Open Access
- Original Research
Anna Papinska, Lakshmi Viswanathan, Qiang Lu, Farida Abane, Charles Psoinos, Rodrigo Ruiz-Soto
Patient-Reported Psychosocial Burdens and Quality of Life and Work Productivity Impacts Among Patients with Clinically Distinct Alopecia Areata Severity Profiles
- Open Access
- Original Research
Kent A. Hanson, Jenny Austin, Nicola Clayton, Peter Anderson, Sergio Vano-Galvan, Simran Marwaha, Samantha K. Kurosky, Alexandre Lejeune, James Piercy, Ernest H. Law
Evaluating the Compositional Quality of Probiotics Containing Bacillus clausii in India
- Open Access
- Original Research
Dhanasekhar Kesavelu, Sridhar Ganpathy, Pramod Jog, Bhaswati Acharya, Vivek Saxena, Nivedita Telang, Nilesh Gaikwad
Real-World Prophylaxis Outcomes with rIX-FP and rFIXFc for Males with Hemophilia B: Pooled Analysis of Medical Chart Data from Germany and Italy
- Open Access
- Original Research
Johannes Oldenburg, Martin Olivieri, Songkai Yan, Ying Yang, Radovan Tomic, Xiang Zhang, Douglass Drelich, Natalie Jakobs, Mariasanta Napolitano
Evaluation of XSB-001 (Ranibizumab Biosimilar) Physicochemical and Biological Stability in Prepared Syringes for Intravitreal Injection
- Open Access
- Original Research
Robert Björnestedt, Sean Waters, Aušrinė Paišytė, Fabricio Furlan, Christian Wanner
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Firsekibart, an Anti-interleukin-1β Monoclonal Antibody, in Healthy Chinese Participants: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
- Open Access
- Original Research
Hongzhong Liu, Yuping Yuan, Wei Tian, Tianhong Luo, Qian Xu, Xiaoyan Zhu, Rui Chen
Body Mass Index Progression, Development of Complications and Healthcare Costs Over 8 Years in UK Individuals Living With Overweight/Obesity
- Open Access
- Original Research
Luca Busetto, Silvia Capucci, João D. da Rocha Fernandes, Sara Holloway, Abd A. Tahrani, Andrew Thompson, Jonathan Pearson-Stuttard
Efficacy and Safety Maintained up to 3 Years in Adults with Paroxysmal Nocturnal Hemoglobinuria Receiving Pegcetacoplan
- Open Access
- Original Research
Carlos de Castro, Richard J. Kelly, Morag Griffin, Christopher J. Patriquin, Brian Mulherin, Britta Höchsmann, Veena Selvaratnam, Raymond Siu Ming Wong, Peter Hillmen, Regina Horneff, Uchendu O. Uchendu, Yiwei Zhang, Elena Surova, Johan Szamosi, Regis Peffault de Latour
Real-World Effectiveness and Safety of Infliximab Biosimilar CT-P13 for Rheumatic Diseases: A National Observational Cohort Study (ReFLECT)
- Open Access
- Original Research
Hubert Marotte, Alain Cantagrel, Fabienne Coury, Thierry Schaeverbeke, Maryse Assing, Meriem Kessouri, Yves Brault, Bruno Fautrel
Pharmacokinetic Bioequivalence, Safety, and Immunogenicity of DMB-3115, an Ustekinumab Biosimilar, and EU- and US-Stelara in Healthy Adult Participants: A Randomized, Double-Blind, Single-Dose Study
- Open Access
- Original Research
Jun Morita, Rainard Fuhr, Thomas Koernicke, Naoki Cho, Thin Thin Mencarini, Hideki Fushimi
When Primary Ciliary Dyskinesia Is Diagnosed in Utero: Insights from Two Families
- Open Access
- Case Series
Israel Amirav, Moria Beer, Dorit Redlich Amirav, Moran Lavie
Ixekizumab Improves Signs, Symptoms, and Quality of Life in Patients with Axial Spondyloarthritis Irrespective of Symptom Duration
- Open Access
- Brief Report
Victoria Navarro-Compán, John D. Reveille, Proton Rahman, José A. Maldonado-Cocco, Marina Magrey, Rebecca Bolce, Tommaso Panni, Andris Kronbergs, Martin Rudwaleit
Correction to: Baricitinib Safety for Events of Special Interest in Populations at Risk: Analysis from Randomised Trial Data Across Rheumatologic and Dermatologic Indications
- Open Access
- Correction
Peter C. Taylor, Thomas Bieber, Rieke Alten, Torsten Witte, James Galloway, Walter Deberdt, Maher Issa, Ewa Haladyj, Inmaculada De La Torre, Susanne Grond, Andreas Wollenberg
Correction to: Repeated Switching Between CT-P17 and EU Reference Adalimumab in Patients with Moderate-to-Severe Chronic Plaque Psoriasis: A Randomized, Double-Blind, Active-Controlled, Phase 3, Interchangeability Study
- Open Access
- Correction
Mark G. Lebwohl, John Y. Koo, Janusz Jaworski, Jakub Trefler, Stefan Daniluk, Anna Dudek, Wojciech Baran, Witold Owczarek, Joanna Kolinek, Paweł Brzewski, Mariusz Sikora, Marek Krogulec, SungHyun Kim, YunJu Bae, DaBee Jeon, EunJin Choi, JungBin Cha, HyunJin Lee, SuJin Choi, David M. Pariser
Correction to: Effectiveness and Safety of Tezepelumab in a Diverse Population of US Patients with Severe Asthma: Initial Results of the PASSAGE Study
- Open Access
- Correction
Njira L. Lugogo, Praveen Akuthota, Kaharu Sumino, Sameer K. Mathur, Autumn F. Burnette, Andrew W. Lindsley, Jean-Pierre Llanos, Claudio Marchese, Christopher S. Ambrose, Benjamin Emmanuel
