Skip to main content
Erschienen in:

05.12.2018 | Ästhetische Dermatologie | Zertifizierte Fortbildung

Von der Alopecia areata bis zum metabolischen Syndrom

Psoriasis und Komorbidität

verfasst von: PD Dr. med. Arnd Jacobi, M.A.

Erschienen in: ästhetische dermatologie & kosmetologie | Ausgabe 6/2018

Einloggen, um Zugang zu erhalten

Zusammenfassung

Bei Patienten mit Psoriasis schränken häufig komorbide Störungen die Lebensqualität zusätzlich ein. Dazu tragen auch Stigmatisierung und Unverständnis gegenüber den Betroffenen bei. Ursache dafür sind vor allem die Äußerlich sichtbaren Erkrankungssymptome. Hier kann die Ästhetische Dermatologie entscheidend Einfluss nehmen, wenn sie in das Gesamtbehandlungskonzept der Psoriasis implementiert wird.
Literatur
2.
Zurück zum Zitat Augustin M et al. A framework for improving the quality of care for people with psoriasis. J Eur Acad Dermatol Venereol. 2012; 26 Suppl 4:1–16PubMedCrossRef Augustin M et al. A framework for improving the quality of care for people with psoriasis. J Eur Acad Dermatol Venereol. 2012; 26 Suppl 4:1–16PubMedCrossRef
3.
Zurück zum Zitat Schäfer I et al. Epidemiologie der Psoriasis in Deutschland — Auswertung von Sekundärdaten einer gesetzlichen Krankenversicherung. Gesundheitswesen. 2011;73: 308–13PubMedCrossRef Schäfer I et al. Epidemiologie der Psoriasis in Deutschland — Auswertung von Sekundärdaten einer gesetzlichen Krankenversicherung. Gesundheitswesen. 2011;73: 308–13PubMedCrossRef
4.
Zurück zum Zitat Schmid-Ott G et al. Psychosoziale Folgen der Psoriasis — eine empirische Studie über die Krankheitslast bei 3753 Betroffenen. Hautarzt. 2005; 56: 466–72PubMedCrossRef Schmid-Ott G et al. Psychosoziale Folgen der Psoriasis — eine empirische Studie über die Krankheitslast bei 3753 Betroffenen. Hautarzt. 2005; 56: 466–72PubMedCrossRef
5.
Zurück zum Zitat Alpsoy E et al. Internalized stigma in psoriasis: a multicenter study. J Dermatol. 2017; 44: 885–91PubMedCrossRef Alpsoy E et al. Internalized stigma in psoriasis: a multicenter study. J Dermatol. 2017; 44: 885–91PubMedCrossRef
6.
Zurück zum Zitat Hawro M et al. Lesions on the back of hands and female gender predispose to stigmatization in patients with psoriasis. J Am Acad Dermatol. 2017; 76: 648–54PubMedCrossRef Hawro M et al. Lesions on the back of hands and female gender predispose to stigmatization in patients with psoriasis. J Am Acad Dermatol. 2017; 76: 648–54PubMedCrossRef
7.
Zurück zum Zitat Masaki S et al. Treatment satisfaction, willingness to pay and quality of life in Japanese patients with psoriasis. J Dermatol. 2017; 44:143–6PubMedCrossRef Masaki S et al. Treatment satisfaction, willingness to pay and quality of life in Japanese patients with psoriasis. J Dermatol. 2017; 44:143–6PubMedCrossRef
8.
Zurück zum Zitat Schöffski O et al. Costs and quality of life in patients with moderate to severe plaque-type psoriasis in Germany: Amulit-centre study. JDDG. 2007; 3: 209–18CrossRef Schöffski O et al. Costs and quality of life in patients with moderate to severe plaque-type psoriasis in Germany: Amulit-centre study. JDDG. 2007; 3: 209–18CrossRef
9.
Zurück zum Zitat Asahina A et al. Serum C-reactive protein levels in Japanese patients with psoriasis and psoriatic arthritis: long-term differential effects of biologics. J Dermatol. 2016; 43:779–84PubMedCrossRef Asahina A et al. Serum C-reactive protein levels in Japanese patients with psoriasis and psoriatic arthritis: long-term differential effects of biologics. J Dermatol. 2016; 43:779–84PubMedCrossRef
10.
Zurück zum Zitat Takata T et al. Detection of asymptomatic enthesitis in psoriasis patients: an onset of psoriatic arthritis? J Dermatol. 2016; 43: 650–4PubMedCrossRef Takata T et al. Detection of asymptomatic enthesitis in psoriasis patients: an onset of psoriatic arthritis? J Dermatol. 2016; 43: 650–4PubMedCrossRef
11.
Zurück zum Zitat Yamamoto T et al. Epidemiological analysis of psoriatic arthritis patients in Japan. J Dermatol. 2016; 43:1193–6PubMedCrossRef Yamamoto T et al. Epidemiological analysis of psoriatic arthritis patients in Japan. J Dermatol. 2016; 43:1193–6PubMedCrossRef
12.
Zurück zum Zitat Yamamoto T et al. Prevalence and current therapies of psoriatic arthritis in Japan: a survey by the Japanese Society of Psoriasis Research in 2016. J Dermatol. 2017; 44: e121PubMedCrossRef Yamamoto T et al. Prevalence and current therapies of psoriatic arthritis in Japan: a survey by the Japanese Society of Psoriasis Research in 2016. J Dermatol. 2017; 44: e121PubMedCrossRef
13.
Zurück zum Zitat Stuart PE et al. Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture. Am J Hum Genet. 2015; 97: 816–36PubMedPubMedCentralCrossRef Stuart PE et al. Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture. Am J Hum Genet. 2015; 97: 816–36PubMedPubMedCentralCrossRef
14.
Zurück zum Zitat Reich K et al. Epidemiology and clinical pattern of psoriatic arthritis in Germany: a prospective interdisciplinary epidemiological study of 1511 patients with plaque-type psoriasis. BJD. 2009; 160: 1040–7CrossRef Reich K et al. Epidemiology and clinical pattern of psoriatic arthritis in Germany: a prospective interdisciplinary epidemiological study of 1511 patients with plaque-type psoriasis. BJD. 2009; 160: 1040–7CrossRef
15.
Zurück zum Zitat Zachariae H et al. Quality of Life and Prevalence of Arthritis Reported by 5,795 Members of the Nordic Psoriasis Associations - Data from the Nordic Quality of Life Study. Acta Derm Venereol. 2002; 82: 108–13PubMedCrossRef Zachariae H et al. Quality of Life and Prevalence of Arthritis Reported by 5,795 Members of the Nordic Psoriasis Associations - Data from the Nordic Quality of Life Study. Acta Derm Venereol. 2002; 82: 108–13PubMedCrossRef
16.
17.
Zurück zum Zitat Koch M et al. Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures. J Invest Dermatol. 2015; 135: 1283–93PubMedPubMedCentralCrossRef Koch M et al. Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures. J Invest Dermatol. 2015; 135: 1283–93PubMedPubMedCentralCrossRef
18.
Zurück zum Zitat Parisi R et al. Psoriasis and the risk of major cardiovascular events: cohort study using the Clinical Practice Research Datalink. J Invest Dermatol. 2015; 135: 2189–97PubMedCrossRef Parisi R et al. Psoriasis and the risk of major cardiovascular events: cohort study using the Clinical Practice Research Datalink. J Invest Dermatol. 2015; 135: 2189–97PubMedCrossRef
19.
Zurück zum Zitat Lonnberg AS et al. Association of psoriasis with the risk for type 2 diabetes mellitus and obesity. JAMA Dermatol. 2016; 152: 761–7PubMedCrossRef Lonnberg AS et al. Association of psoriasis with the risk for type 2 diabetes mellitus and obesity. JAMA Dermatol. 2016; 152: 761–7PubMedCrossRef
20.
Zurück zum Zitat Cohen AD et al. Psoriasis and diabetes: a population-based cross-sectional study. J Eur Acad Dermatol Venereol. 2008; 22: 585–9PubMedCrossRef Cohen AD et al. Psoriasis and diabetes: a population-based cross-sectional study. J Eur Acad Dermatol Venereol. 2008; 22: 585–9PubMedCrossRef
21.
Zurück zum Zitat Naito R, Imafuku S. Distinguishing features of body mass index and psoriasis in men and women in Japan: a hospital-based case-control study. J Dermatol. 2016; 43: 1406–11PubMedCrossRef Naito R, Imafuku S. Distinguishing features of body mass index and psoriasis in men and women in Japan: a hospital-based case-control study. J Dermatol. 2016; 43: 1406–11PubMedCrossRef
22.
Zurück zum Zitat Liu JH et al. Relation between endothelial progenitor cells and arterial stiffness in patients with psoriasis. J Dermatol. 2016; 43: 888–93PubMedCrossRef Liu JH et al. Relation between endothelial progenitor cells and arterial stiffness in patients with psoriasis. J Dermatol. 2016; 43: 888–93PubMedCrossRef
23.
Zurück zum Zitat Honma M et al. Close correlation of bone mineral density and body mass index in Japanese psoriasis patients. J Dermatol. 2017; 44: e1–2PubMedCrossRef Honma M et al. Close correlation of bone mineral density and body mass index in Japanese psoriasis patients. J Dermatol. 2017; 44: e1–2PubMedCrossRef
24.
Zurück zum Zitat Chularojanamontri L et al. Metabolic syndrome and psoriasis severity in South-East Asian patients: an investigation of potential association using current and chronological assessments. J Dermatol. 2016; 43: 1424–8PubMedCrossRef Chularojanamontri L et al. Metabolic syndrome and psoriasis severity in South-East Asian patients: an investigation of potential association using current and chronological assessments. J Dermatol. 2016; 43: 1424–8PubMedCrossRef
26.
Zurück zum Zitat Oh EH et al. Epidemiology and cardiovascular comorbidities in patients with psoriasis: a Korean nationwide population-based cohort study. J Dermatol. 2017; 44: 621–9PubMedCrossRef Oh EH et al. Epidemiology and cardiovascular comorbidities in patients with psoriasis: a Korean nationwide population-based cohort study. J Dermatol. 2017; 44: 621–9PubMedCrossRef
27.
Zurück zum Zitat Jacobi A et al. Prevalence of Obesity in Patients with Psoriasis: Results of the National Study PsoHealth3. Dermatology. 2015; 231: 231–8PubMedCrossRef Jacobi A et al. Prevalence of Obesity in Patients with Psoriasis: Results of the National Study PsoHealth3. Dermatology. 2015; 231: 231–8PubMedCrossRef
28.
Zurück zum Zitat Kim DS et al. Assessments of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in Korean patients with psoriasis vulgaris and psoriatic arthritis. J Dermatol. 2016; 43: 305–10PubMedCrossRef Kim DS et al. Assessments of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in Korean patients with psoriasis vulgaris and psoriatic arthritis. J Dermatol. 2016; 43: 305–10PubMedCrossRef
29.
Zurück zum Zitat Pina T et al. Asymmetric dimethylarginine but not osteoprotegerin correlates with disease severity in patients with moderate-to-severe psoriasis undergoing anti-tumor necrosis factor-a therapy. J Dermatol. 2016; 43: 389–94PubMedCrossRef Pina T et al. Asymmetric dimethylarginine but not osteoprotegerin correlates with disease severity in patients with moderate-to-severe psoriasis undergoing anti-tumor necrosis factor-a therapy. J Dermatol. 2016; 43: 389–94PubMedCrossRef
30.
Zurück zum Zitat Sato Y et al. S100A7 expression levels in coordination with interleukin-8 indicate the clinical response to infliximab for psoriasis patients. J Dermatol. 2017; 44: 838–9PubMedCrossRef Sato Y et al. S100A7 expression levels in coordination with interleukin-8 indicate the clinical response to infliximab for psoriasis patients. J Dermatol. 2017; 44: 838–9PubMedCrossRef
31.
Zurück zum Zitat Takahashi T et al. Serum angiopoietin-2 level as a potential biomarker in psoriasis vulgaris. J Dermatol. 2017; 44: 205–6PubMedCrossRef Takahashi T et al. Serum angiopoietin-2 level as a potential biomarker in psoriasis vulgaris. J Dermatol. 2017; 44: 205–6PubMedCrossRef
32.
Zurück zum Zitat Davidovici BB et al. Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and comorbid conditions. J Invest Dermatol. 2010; 130: 1785–96PubMedCrossRef Davidovici BB et al. Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and comorbid conditions. J Invest Dermatol. 2010; 130: 1785–96PubMedCrossRef
34.
Zurück zum Zitat Prinz JC. Autoimmune aspects of psoriasis: heritability and autoantigens. Autoimmun Rev. 2017; 16: 970–9PubMedCrossRef Prinz JC. Autoimmune aspects of psoriasis: heritability and autoantigens. Autoimmun Rev. 2017; 16: 970–9PubMedCrossRef
35.
Zurück zum Zitat Akiyama M et al. Association of psoriasis with Hashimoto’s thyroiditis, Sjögren’s syndrome and dermatomyositis. J Dermatol. 2016; 43: 711–2PubMedCrossRef Akiyama M et al. Association of psoriasis with Hashimoto’s thyroiditis, Sjögren’s syndrome and dermatomyositis. J Dermatol. 2016; 43: 711–2PubMedCrossRef
36.
Zurück zum Zitat Maki N et al. Possible paraneoplastic syndrome case of bullous pemphigoid with immunoglobulin G anti-BP180 C-terminal domain antibodies associated with psoriasis and primary macroglobulinemia. J Dermatol. 2016; 43: 571–4PubMedCrossRef Maki N et al. Possible paraneoplastic syndrome case of bullous pemphigoid with immunoglobulin G anti-BP180 C-terminal domain antibodies associated with psoriasis and primary macroglobulinemia. J Dermatol. 2016; 43: 571–4PubMedCrossRef
37.
Zurück zum Zitat Matsuo H et al. Relapsing polychondritis associated with psoriasis vulgaris successfully treated with adalimumab: a case report with published work review. J Dermatol. 2017; 44: 826–9PubMedCrossRef Matsuo H et al. Relapsing polychondritis associated with psoriasis vulgaris successfully treated with adalimumab: a case report with published work review. J Dermatol. 2017; 44: 826–9PubMedCrossRef
38.
Zurück zum Zitat Jacobi A, Kupke C, Behzad M, Hertl M. Comorbidities, metabolic risk profile and health-related quality of life in German patients with plaque-type psoriasis: a cross-sectional prospective study. Int J Dermatol. 2013; 52: 1081–7PubMedCrossRef Jacobi A, Kupke C, Behzad M, Hertl M. Comorbidities, metabolic risk profile and health-related quality of life in German patients with plaque-type psoriasis: a cross-sectional prospective study. Int J Dermatol. 2013; 52: 1081–7PubMedCrossRef
40.
Zurück zum Zitat Gelfand JM et al. The risk of mortality in patients with psoriasis: results from a population-based study. Arch Dermatol. 2007; 143: 1493–9PubMed Gelfand JM et al. The risk of mortality in patients with psoriasis: results from a population-based study. Arch Dermatol. 2007; 143: 1493–9PubMed
41.
Zurück zum Zitat Augustin M et al. Co-morbidity and age-related prevalence of psoriasis: Analysis of health insurance data in Germany. Acta DermVenereol. 2010; 90: 147–51 Augustin M et al. Co-morbidity and age-related prevalence of psoriasis: Analysis of health insurance data in Germany. Acta DermVenereol. 2010; 90: 147–51
42.
Zurück zum Zitat Dorschner RA et al. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol. 2001; 117: 91–7PubMedCrossRef Dorschner RA et al. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. J Invest Dermatol. 2001; 117: 91–7PubMedCrossRef
44.
Zurück zum Zitat Lande R et al. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 2007; 449: 564–9PubMedCrossRef Lande R et al. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 2007; 449: 564–9PubMedCrossRef
46.
Zurück zum Zitat Teng MW et al. IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases. Nat Med. 2015; 21: 719–29PubMedCrossRef Teng MW et al. IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases. Nat Med. 2015; 21: 719–29PubMedCrossRef
47.
Zurück zum Zitat Boniface K et al. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol. 2005; 174: 3695–702PubMedCrossRef Boniface K et al. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J Immunol. 2005; 174: 3695–702PubMedCrossRef
48.
Zurück zum Zitat Sa SM et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol. 2007; 178: 2229–40PubMedCrossRef Sa SM et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol. 2007; 178: 2229–40PubMedCrossRef
49.
Zurück zum Zitat Menter A et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 6. Guidelines of care for the treatment of psoriasis and psoriatic arthritis: case-based presentations and evidencebased conclusions. J Am Acad Dermatol. 2011; 65: 137–74PubMedCrossRef Menter A et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 6. Guidelines of care for the treatment of psoriasis and psoriatic arthritis: case-based presentations and evidencebased conclusions. J Am Acad Dermatol. 2011; 65: 137–74PubMedCrossRef
50.
Zurück zum Zitat Jabbar-Lopez ZK et al. Quantitative evaluation of biologic therapy options for psoriasis: a systematic review and network meta-analysis. J Invest Dermatol. 2017; 137: 1646–54PubMedPubMedCentralCrossRef Jabbar-Lopez ZK et al. Quantitative evaluation of biologic therapy options for psoriasis: a systematic review and network meta-analysis. J Invest Dermatol. 2017; 137: 1646–54PubMedPubMedCentralCrossRef
51.
Zurück zum Zitat Torii H et al. Efficacy and safety of dose escalation of infliximab therapy in Japanese patients with psoriasis: results of the SPREAD study. J Dermatol. 2017; 44: 552–9PubMedCrossRef Torii H et al. Efficacy and safety of dose escalation of infliximab therapy in Japanese patients with psoriasis: results of the SPREAD study. J Dermatol. 2017; 44: 552–9PubMedCrossRef
52.
Zurück zum Zitat Torii H et al. Safety profiles and efficacy of infliximab therapy in Japanese patients with plaque psoriasis with or without psoriatic arthritis, pustular psoriasis or psoriatic erythroderma: results from the prospective post-marketing surveillance. J Dermatol. 2016; 43: 767–78PubMedCrossRef Torii H et al. Safety profiles and efficacy of infliximab therapy in Japanese patients with plaque psoriasis with or without psoriatic arthritis, pustular psoriasis or psoriatic erythroderma: results from the prospective post-marketing surveillance. J Dermatol. 2016; 43: 767–78PubMedCrossRef
53.
Zurück zum Zitat Imafuku S et al. Efficacy and safety of secukinumab in patients with generalized pustular psoriasis: a 52-week analysis from phase III open-label multicenter Japanese study. J Dermatol. 2016; 43: 1011–7PubMedCrossRef Imafuku S et al. Efficacy and safety of secukinumab in patients with generalized pustular psoriasis: a 52-week analysis from phase III open-label multicenter Japanese study. J Dermatol. 2016; 43: 1011–7PubMedCrossRef
54.
Zurück zum Zitat Asahina A et al. Safety and efficacy of adalimumab treatment in Japanese patients with psoriasis: results of SALSA study. J Dermatol. 2016; 43: 1257–66PubMedPubMedCentralCrossRef Asahina A et al. Safety and efficacy of adalimumab treatment in Japanese patients with psoriasis: results of SALSA study. J Dermatol. 2016; 43: 1257–66PubMedPubMedCentralCrossRef
55.
Zurück zum Zitat Saeki H et al. Efficacy and safety of ixekizumab treatment for Japanese patients with moderate to severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis: results from a 52-week, open-label, phase 3 study (UNCOVER-J). J Dermatol. 2017; 44: 355–62PubMedCrossRef Saeki H et al. Efficacy and safety of ixekizumab treatment for Japanese patients with moderate to severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis: results from a 52-week, open-label, phase 3 study (UNCOVER-J). J Dermatol. 2017; 44: 355–62PubMedCrossRef
56.
Zurück zum Zitat Matsumoto A et al. Adalimumab administration after infliximab therapy is a successful treatment strategy for generalized pustular psoriasis. J Dermatol. 2017; 44: 202–4PubMedCrossRef Matsumoto A et al. Adalimumab administration after infliximab therapy is a successful treatment strategy for generalized pustular psoriasis. J Dermatol. 2017; 44: 202–4PubMedCrossRef
57.
Zurück zum Zitat Hwang YJ et al. Clinical factors predicting the therapeutic response to ustekinumab in patients with moderate to severe chronic plaque psoriasis. J Dermatol. 2017; 44: 560–6PubMedCrossRef Hwang YJ et al. Clinical factors predicting the therapeutic response to ustekinumab in patients with moderate to severe chronic plaque psoriasis. J Dermatol. 2017; 44: 560–6PubMedCrossRef
58.
Zurück zum Zitat Lande R et al. The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis. Nat Commun. 2014; 5: 5621PubMedCrossRef Lande R et al. The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis. Nat Commun. 2014; 5: 5621PubMedCrossRef
59.
Zurück zum Zitat Lande R et al. Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA. Eur J Immunol. 2015; 45: 203–13PubMedCrossRef Lande R et al. Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA. Eur J Immunol. 2015; 45: 203–13PubMedCrossRef
62.
Zurück zum Zitat Gudjonsson JE et al. HLA-Cw6-positive and HLA-Cw6-negative patients with Psoriasis vulgaris have distinct clinical features. J Invest Dermatol. 2002; 118: 362–5PubMedCrossRef Gudjonsson JE et al. HLA-Cw6-positive and HLA-Cw6-negative patients with Psoriasis vulgaris have distinct clinical features. J Invest Dermatol. 2002; 118: 362–5PubMedCrossRef
63.
Zurück zum Zitat Gudjonsson JE et al. Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2.5-fold increased risk of developing psoriasis compared with Cw6 heterozygotes. Br J Dermatol. 2003; 148: 233–5PubMedCrossRef Gudjonsson JE et al. Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2.5-fold increased risk of developing psoriasis compared with Cw6 heterozygotes. Br J Dermatol. 2003; 148: 233–5PubMedCrossRef
64.
Zurück zum Zitat Plewig G et al. Braun-Falco’s Dermatologie, Venerologie und Allergologie. 6. überarbeitete und erweiterte Auflage. Berlin, Heidelberg: Springer; 2012 Plewig G et al. Braun-Falco’s Dermatologie, Venerologie und Allergologie. 6. überarbeitete und erweiterte Auflage. Berlin, Heidelberg: Springer; 2012
65.
Zurück zum Zitat Tsai TF et al. Epidemiology and comorbidities of psoriasis patients in a national database in Taiwan. J Dermatol Sci. 2011; 63: 40–6PubMedCrossRef Tsai TF et al. Epidemiology and comorbidities of psoriasis patients in a national database in Taiwan. J Dermatol Sci. 2011; 63: 40–6PubMedCrossRef
66.
Zurück zum Zitat Wu JJ et al. The association of psoriasis with autoimmune diseases. J Am Acad Dermatol. 2012; 67: 924–30PubMedCrossRef Wu JJ et al. The association of psoriasis with autoimmune diseases. J Am Acad Dermatol. 2012; 67: 924–30PubMedCrossRef
67.
Zurück zum Zitat Kridin K, Bergman R. Association between bullous pemphigoid and psoriasis: a case-control study. J Am Acad Dermatol. 2017; 77: 370–2PubMedCrossRef Kridin K, Bergman R. Association between bullous pemphigoid and psoriasis: a case-control study. J Am Acad Dermatol. 2017; 77: 370–2PubMedCrossRef
68.
Zurück zum Zitat Ohata C et al. Coexistence of autoimmune bullous diseases (AIBDs) and psoriasis: a series of 145 cases. J Am Acad Dermatol. 2015; 73: 50–5PubMedCrossRef Ohata C et al. Coexistence of autoimmune bullous diseases (AIBDs) and psoriasis: a series of 145 cases. J Am Acad Dermatol. 2015; 73: 50–5PubMedCrossRef
69.
Zurück zum Zitat Chen YJ et al. Comorbidity profiles among patients with bullous pemphigoid: a nationwide population-based study. Br J Dermatol. 2011; 165: 593–9PubMedCrossRef Chen YJ et al. Comorbidity profiles among patients with bullous pemphigoid: a nationwide population-based study. Br J Dermatol. 2011; 165: 593–9PubMedCrossRef
70.
Zurück zum Zitat Arunachalam M et al. Non-seg- mental vitiligo and psoriasis comorbidity — a case-control study in Italian patients. J Eur Acad Dermatol Venereol. 2014; 28: 433–7PubMedCrossRef Arunachalam M et al. Non-seg- mental vitiligo and psoriasis comorbidity — a case-control study in Italian patients. J Eur Acad Dermatol Venereol. 2014; 28: 433–7PubMedCrossRef
71.
Zurück zum Zitat Blegvad C et al. Autoimmune disease in children and adolescents with psoriasis: a cross-sectional study in Denmark. Acta Derm Venereol. 2017; 97: 1225–29PubMedCrossRef Blegvad C et al. Autoimmune disease in children and adolescents with psoriasis: a cross-sectional study in Denmark. Acta Derm Venereol. 2017; 97: 1225–29PubMedCrossRef
73.
Zurück zum Zitat Henseler T, Christophers E. Disease concomitance in psoriasis. J Am Acad Dermatol. 1995; 32: 982–6PubMedCrossRef Henseler T, Christophers E. Disease concomitance in psoriasis. J Am Acad Dermatol. 1995; 32: 982–6PubMedCrossRef
74.
Zurück zum Zitat Ludwig RJ et al. Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol. 2007; 156: 271–6PubMedCrossRef Ludwig RJ et al. Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol. 2007; 156: 271–6PubMedCrossRef
75.
Zurück zum Zitat Patel RV et al. Psoriasis and vascular disease-risk factors and outcomes: a systematic review of the literature. J Gen Intern Med. 2011; 26: 1036–49PubMedPubMedCentralCrossRef Patel RV et al. Psoriasis and vascular disease-risk factors and outcomes: a systematic review of the literature. J Gen Intern Med. 2011; 26: 1036–49PubMedPubMedCentralCrossRef
76.
Zurück zum Zitat Mallbris L et al. Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients. Eur J Epidemiol. 2004; 19: 225–30PubMedCrossRef Mallbris L et al. Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients. Eur J Epidemiol. 2004; 19: 225–30PubMedCrossRef
77.
Zurück zum Zitat Gelfand JM et al. Risk of myocardial infarction in patients with psoriasis. JAMA. 2006; 296: 1735–41PubMedCrossRef Gelfand JM et al. Risk of myocardial infarction in patients with psoriasis. JAMA. 2006; 296: 1735–41PubMedCrossRef
78.
Zurück zum Zitat Boehncke WH et al. The ‚psoriatic march‘: a concept of how severe psoriasis may drive cardiovascular comorbidity. Exp Dermatol. 2011; 20: 303–7PubMedCrossRef Boehncke WH et al. The ‚psoriatic march‘: a concept of how severe psoriasis may drive cardiovascular comorbidity. Exp Dermatol. 2011; 20: 303–7PubMedCrossRef
79.
Zurück zum Zitat Jacobsson LT et al. Treatment with tumor necrosis factor blockers is associated with a lower incidence of first cardiovascuar events in patients with rheumatoid arthritis. J Rheumatol. 2005. 32: 1213–8PubMed Jacobsson LT et al. Treatment with tumor necrosis factor blockers is associated with a lower incidence of first cardiovascuar events in patients with rheumatoid arthritis. J Rheumatol. 2005. 32: 1213–8PubMed
80.
Zurück zum Zitat Wolk K et al. Excessive body weight and smoking associates with a high risk of onset of plaque psoriasis. Acta Derm Venereol. 2009; 89: 492–7PubMedCrossRef Wolk K et al. Excessive body weight and smoking associates with a high risk of onset of plaque psoriasis. Acta Derm Venereol. 2009; 89: 492–7PubMedCrossRef
81.
Zurück zum Zitat Setty AR et al. Obesity, waist circumference, weight change, and the risk of psoriasis in women: Nurses’ Health Study II. Arch Intern Med. 2007; 167: 1670–5PubMedCrossRef Setty AR et al. Obesity, waist circumference, weight change, and the risk of psoriasis in women: Nurses’ Health Study II. Arch Intern Med. 2007; 167: 1670–5PubMedCrossRef
82.
Zurück zum Zitat Van Kruijsdijk RC et al. Obesity and cancer: the role of dysfunctional adipose tissue. Cancer Epidemiol Biomarkers Prev. 2009; 18: 2569–78PubMedCrossRef Van Kruijsdijk RC et al. Obesity and cancer: the role of dysfunctional adipose tissue. Cancer Epidemiol Biomarkers Prev. 2009; 18: 2569–78PubMedCrossRef
84.
Zurück zum Zitat weltpsoriasistag.de [Internet]. Hamburg: Competenzzentrum Versorgungsforschung in der Dermatologie Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen [zitiert am 22.10.2018]. Verfügbar unter www.weltpsoriasistag.de weltpsoriasistag.de [Internet]. Hamburg: Competenzzentrum Versorgungsforschung in der Dermatologie Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen [zitiert am 22.10.2018]. Verfügbar unter www.​weltpsoriasistag​.​de
85.
Zurück zum Zitat Kerscher M. Dermatokosmetik. 2. bearbeitete und erweiterte Auflage. Berlin Hedielberg: Springer; 2009 Kerscher M. Dermatokosmetik. 2. bearbeitete und erweiterte Auflage. Berlin Hedielberg: Springer; 2009
Metadaten
Titel
Von der Alopecia areata bis zum metabolischen Syndrom
Psoriasis und Komorbidität
verfasst von
PD Dr. med. Arnd Jacobi, M.A.
Publikationsdatum
05.12.2018
Verlag
Springer Medizin
Erschienen in
ästhetische dermatologie & kosmetologie / Ausgabe 6/2018
Print ISSN: 1867-481X
Elektronische ISSN: 2198-6517
DOI
https://doi.org/10.1007/s12634-018-5563-y

Passend zum Thema

Allergen unter der Haut: Wenn Tattoos plötzlich Ärger machen

Tätowierungen können nicht nur künstlerisch, sondern auch gesundheitlich komplex sein. Manche Pigmente bergen Gefahren, die sich oft erst Jahre später zeigen. Was steckt hinter den verzögerten Reaktionen, und wie kann man sie behandeln?

ANZEIGE

Erhöhte Aufnahme von Tattoofarbe mit Dexpanthenol

PD Dr. Matthias Bartneck, forschender Biologe an der RWTH Aachen, stellte eine aktuelle in-vitro Studie vor, bei welcher unter anderem der Einfluss von Dexpanthenol auf die Aufnahme von Tattoo-Farbe sowie die Beständigkeit der Farben unter der Haut untersucht wurden. Andy Engel, Tätowierer, berichtete von seinen Erfahrungen aus dem Tattoo-Studio.

ANZEIGE

Bepanthen® unterstützt bei vielen Indikationen die Regeneration der Haut

  • Content Hub

Bepanthen® Wund- und Heilsalbe wird heute wie bei der Einführung vor 70 Jahren erfolgreich bei kleinen Alltagsverletzungen eingesetzt. Moderne Forschung – Untersuchungen an Hautmodellen, Genexpressionsanalysen und klinische Studien – schafft darüber hinaus Evidenz für neue Anwendungsgebiete. So kann die Dexpanthenol-haltige Salbe heute z.B. zur Nachbehandlung einer Lasertherapie bei aktinischer Keratose oder Tattoo-Entfernung eingesetzt werden. Erfahren Sie hier mehr über moderne Forschung zu Bepanthen.

Bayer Vital GmbH

Passend zum Thema

ANZEIGE

Lebensqualität bei atopischer Dermatitis: Interview mit Prof. Diamant Thaçi

Die atopische Dermatitis (AD) greift tief in den Alltag der Betroffenen ein – besonders Juckreiz und schlechter Schlaf mindern die Lebensqualität spürbar. Wie stark der Schweregrad von AD das Wohlbefinden prägt und wie die Lebensqualität langfristig gesteigert werden kann, erläutert Prof. Diamant Thaçi im Interview.

ANZEIGE

Atopische Dermatitis schläft nicht: Interview mit Dr. Caroline Mann

Erholsamer Schlaf ist entscheidend für Wohlbefinden, Leistungsfähigkeit und ein starkes Immunsystem. Bei atopischer Dermatitis kann nächtlicher Juckreiz Schlafstörungen verursachen und die Lebensqualität erheblich mindern. In einem Interview präsentiert Dr. Caroline Mann spannende Studien, die den engen Zusammenhang zwischen Schlafqualität und AD verdeutlichen.

ANZEIGE

Neueste Erkenntnisse zum Hautmikrobiom: vier Experten im Gespräch

  • Content Hub

Die Experten Prof. Luger (Münster), Prof. Zuberbier (Berlin), Prof. Thaçi (Lübeck) und PD Dr. Jansen (Essen) erörtern im von La Roche Posay unterstützen Expertenworkshop die Bedeutung des Mikrobioms für verschiedene Hautkrankheiten wie atopische Dermatitis, Akne oder Rosazea.

La Roche Posay