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08.01.2016 | Review Article | Ausgabe 3/2016

Age-associated events in bovine oocytes and possible countermeasures

Zeitschrift:: Reproductive Medicine and Biology > Ausgabe 3/2016

Autor:: Hisataka Iwata

Abstract

Maternal aging profoundly affects oocyte quality. This has become common knowledge in industrialized countries and extensive studies addressing the causes and possible countermeasures against age-associated deterioration of oocytes suggest that mitochondrial dysfunction is a causal factor in infertility. However, almost all studies addressing age-associated events in oocytes have used mice as an animal model, and the reproductive life of mice is very short, making it difficult to study the gradual decline in fertility observed in humans. In the present review, age-associated changes in the quality and quantity of bovine oocytes and possible countermeasures related to mitochondrial quality control are introduced.

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Titel: Age-associated events in bovine oocytes and possible countermeasures
Autor:: Hisataka Iwata
Publikationsdatum: 08.01.2016
DOI: https://doi.org/10.1007/s12522-015-0233-5
Verlag: Springer Japan
Zeitschrift: Reproductive Medicine and Biology
Ausgabe 3/2016
Print ISSN: 1445-5781
Elektronische ISSN: 1447-0578

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Age-associated events in bovine oocytes and possible countermeasures

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