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08.10.2018 | Original Article

Agreement between left ventricular ejection fraction assessed in patients with gated IQ-SPECT and conventional imaging

Zeitschrift:
Journal of Nuclear Cardiology
Autoren:
MD Lucia Leva, PhD Roberta Matheoud, MD Gianmauro Sacchetti, MD Alessandro Carriero, PhD Marco Brambilla
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s12350-018-1457-7) contains supplementary material, which is available to authorized users.
The authors of this article have provided a PowerPoint file, available for download at SpringerLink, which summarises the contents of the paper and is free for re-use at meetings and presentations. Search for the article DOI on SpringerLink.com.

Funding

None.

Abstract

Background

The aim of the study was to assess the agreement between the left ventricular ejection fraction (LVEF) values obtained with IQ-SPECT and those obtained with a conventional gamma camera equipped with low-energy high-resolution (LEHR), considered as the method of reference.

Methods

Gated-stress MPI using 99mTc-tetrofosmin was performed in 55 consecutive patients. The patients underwent two sequential acquisitions (Method A and B) performed on Symbia-IQ SPECT with different acquisition times and one (Method C) on a Ecam SPECT equipped with LEHR collimators. The values of the different datasets were compared using the Bland-Altman analysis method: the bias and the limits of agreement (LA) were estimated in a head-to-head comparison of the three protocols.

Results

In the (Method A-Method C) comparison for LVEF, the bias was 3.8% and the LAs ranged from − 9.3% to 16.8%. The agreement was still lower between Method B and C, whilst only slightly improved when Methods A and B were compared.

Conclusions

The wide amplitude in LA intervals of about 30% indicates that IQ and LEHR GSPECT are not interchangeable. The values obtained with IQ-SPECT should only be used with caution when evaluating the functional state of the heart.

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Zusatzmaterial
Supplementary material 1 (PPTX 191 kb)
12350_2018_1457_MOESM1_ESM.pptx
Literatur
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