Skip to main content
Erschienen in: Cancer and Metastasis Reviews 3/2017

16.08.2017

Alcohol and head and neck cancer

verfasst von: Daisuke Kawakita, Keitaro Matsuo

Erschienen in: Cancer and Metastasis Reviews | Ausgabe 3/2017

Einloggen, um Zugang zu erhalten

Abstract

In this article, we reviewed the association between alcohol drinking and head and neck cancer (HNC) and its subsites, using the available literature. Alcohol drinking is an established risk factor for HNC, and this association may be stronger among cancers of the oropharynx and hypopharynx than the oral cavity or larynx. In addition, higher alcohol consumption over a shorter period was more harmful than fewer alcohol consumption over a longer period, and the most frequently consumed alcoholic beverages in a population is likely to be associated with the highest risk of HNC in that population. The risk of HNC after ≥ 20 years of alcohol cessation appear to be similar to the risk among never drinkers. The interaction between genetic polymorphisms related to alcohol metabolism and alcohol drinking on the risk of HNC has been noted, and the prevalence of these genetic polymorphisms in each population should be of concern. Finally, the association between alcohol drinking and the survival of individuals with HNC remains unclear, and mortality due to competing causes should be considered in future research to evaluate this association.
Literatur
1.
Zurück zum Zitat Ferlay, J., Shin, H. R., Bray, F., Forman, D., Mathers, C., & Parkin, D. M. (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. International Journal of Cancer, 127(12), 2893–2917.PubMedCrossRef Ferlay, J., Shin, H. R., Bray, F., Forman, D., Mathers, C., & Parkin, D. M. (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. International Journal of Cancer, 127(12), 2893–2917.PubMedCrossRef
2.
Zurück zum Zitat Hashibe, M., Brennan, P., Benhamou, S., Castellsague, X., Chen, C., Curado, M. P., et al. (2007). Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the international head and neck cancer epidemiology consortium. Journal of the National Cancer Institute, 99(10), 777–789.PubMedCrossRef Hashibe, M., Brennan, P., Benhamou, S., Castellsague, X., Chen, C., Curado, M. P., et al. (2007). Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the international head and neck cancer epidemiology consortium. Journal of the National Cancer Institute, 99(10), 777–789.PubMedCrossRef
3.
Zurück zum Zitat Gillison, M. L., Chaturvedi, A. K., Anderson, W. F., & Fakhry, C. (2015). Epidemiology of human papillomavirus-positive head and neck squamous cell carcinoma. Journal of Clinical Oncology, 33(29), 3235–3242.PubMedPubMedCentralCrossRef Gillison, M. L., Chaturvedi, A. K., Anderson, W. F., & Fakhry, C. (2015). Epidemiology of human papillomavirus-positive head and neck squamous cell carcinoma. Journal of Clinical Oncology, 33(29), 3235–3242.PubMedPubMedCentralCrossRef
4.
Zurück zum Zitat IARC Working Group. (1988). Alcohol drinking. Lyon: International Agency for Research on Cancer. IARC Working Group. (1988). Alcohol drinking. Lyon: International Agency for Research on Cancer.
5.
Zurück zum Zitat Bagnardi, V., Rota, M., Botteri, E., Tramacere, I., Islami, F., Fedirko, V., et al. (2015). Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis. British Journal of Cancer, 112(3), 580–593.PubMedCrossRef Bagnardi, V., Rota, M., Botteri, E., Tramacere, I., Islami, F., Fedirko, V., et al. (2015). Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis. British Journal of Cancer, 112(3), 580–593.PubMedCrossRef
6.
Zurück zum Zitat Turati, F., Garavello, W., Tramacere, I., Pelucchi, C., Galeone, C., Bagnardi, V., et al. (2013). A meta-analysis of alcohol drinking and oral and pharyngeal cancers: results from subgroup analyses. Alcohol and Alcoholism, 48(1), 107–118.PubMedCrossRef Turati, F., Garavello, W., Tramacere, I., Pelucchi, C., Galeone, C., Bagnardi, V., et al. (2013). A meta-analysis of alcohol drinking and oral and pharyngeal cancers: results from subgroup analyses. Alcohol and Alcoholism, 48(1), 107–118.PubMedCrossRef
7.
Zurück zum Zitat Bagnardi, V., Rota, M., Botteri, E., Tramacere, I., Islami, F., Fedirko, V., et al. (2013). Light alcohol drinking and cancer: a meta-analysis. Annals of Oncology, 24(2), 301–308.PubMedCrossRef Bagnardi, V., Rota, M., Botteri, E., Tramacere, I., Islami, F., Fedirko, V., et al. (2013). Light alcohol drinking and cancer: a meta-analysis. Annals of Oncology, 24(2), 301–308.PubMedCrossRef
8.
Zurück zum Zitat Turati, F., Garavello, W., Tramacere, I., Bagnardi, V., Rota, M., Scotti, L., et al. (2010). A meta-analysis of alcohol drinking and oral and pharyngeal cancers. Part 2: results by subsites. Oral Oncology, 46(10), 720–726.PubMedCrossRef Turati, F., Garavello, W., Tramacere, I., Bagnardi, V., Rota, M., Scotti, L., et al. (2010). A meta-analysis of alcohol drinking and oral and pharyngeal cancers. Part 2: results by subsites. Oral Oncology, 46(10), 720–726.PubMedCrossRef
9.
Zurück zum Zitat Tramacere, I., Negri, E., Bagnardi, V., Garavello, W., Rota, M., Scotti, L., et al. (2010). A meta-analysis of alcohol drinking and oral and pharyngeal cancers. Part 1: overall results and dose-risk relation. Oral Oncology, 46(7), 497–503.PubMedCrossRef Tramacere, I., Negri, E., Bagnardi, V., Garavello, W., Rota, M., Scotti, L., et al. (2010). A meta-analysis of alcohol drinking and oral and pharyngeal cancers. Part 1: overall results and dose-risk relation. Oral Oncology, 46(7), 497–503.PubMedCrossRef
10.
Zurück zum Zitat Goldstein, B. Y., Chang, S. C., Hashibe, M., La Vecchia, C., & Zhang, Z. F. (2010). Alcohol consumption and cancers of the oral cavity and pharynx from 1988 to 2009: an update. European Journal of Cancer Prevention, 19(6), 431–465.PubMedPubMedCentralCrossRef Goldstein, B. Y., Chang, S. C., Hashibe, M., La Vecchia, C., & Zhang, Z. F. (2010). Alcohol consumption and cancers of the oral cavity and pharynx from 1988 to 2009: an update. European Journal of Cancer Prevention, 19(6), 431–465.PubMedPubMedCentralCrossRef
11.
Zurück zum Zitat Bagnardi, V., Blangiardo, M., La Vecchia, C., & Corrao, G. (2001). A meta-analysis of alcohol drinking and cancer risk. British Journal of Cancer, 85(11), 1700–1705.PubMedPubMedCentralCrossRef Bagnardi, V., Blangiardo, M., La Vecchia, C., & Corrao, G. (2001). A meta-analysis of alcohol drinking and cancer risk. British Journal of Cancer, 85(11), 1700–1705.PubMedPubMedCentralCrossRef
12.
Zurück zum Zitat Islami, F., Tramacere, I., Rota, M., Bagnardi, V., Fedirko, V., Scotti, L., et al. (2010). Alcohol drinking and laryngeal cancer: overall and dose-risk relation--a systematic review and meta-analysis. Oral Oncology, 46(11), 802–810.PubMedCrossRef Islami, F., Tramacere, I., Rota, M., Bagnardi, V., Fedirko, V., Scotti, L., et al. (2010). Alcohol drinking and laryngeal cancer: overall and dose-risk relation--a systematic review and meta-analysis. Oral Oncology, 46(11), 802–810.PubMedCrossRef
13.
Zurück zum Zitat Praud, D., Rota, M., Rehm, J., Shield, K., Zatonski, W., Hashibe, M., et al. (2016). Cancer incidence and mortality attributable to alcohol consumption. International Journal of Cancer, 138(6), 1380–1387.PubMedCrossRef Praud, D., Rota, M., Rehm, J., Shield, K., Zatonski, W., Hashibe, M., et al. (2016). Cancer incidence and mortality attributable to alcohol consumption. International Journal of Cancer, 138(6), 1380–1387.PubMedCrossRef
14.
Zurück zum Zitat Carlson, J., Licitra, L., Locati, L., Raben, D., Persson, F., & Stenman, G. (2013). Salivary gland cancer: an update on present and emerging therapies. American Socety of Clinical Oncology Educational Book, 257–263. doi:10.1200/EdBook_AM.2013.33.257. Carlson, J., Licitra, L., Locati, L., Raben, D., Persson, F., & Stenman, G. (2013). Salivary gland cancer: an update on present and emerging therapies. American Socety of Clinical Oncology Educational Book, 257–263. doi:10.​1200/​EdBook_​AM.​2013.​33.​257.
15.
Zurück zum Zitat Youlden, D. R., Cramb, S. M., Peters, S., Porceddu, S. V., Moller, H., Fritschi, L., et al. (2013). International comparisons of the incidence and mortality of sinonasal cancer. Cancer Epidemiology, 37(6), 770–779.PubMedCrossRef Youlden, D. R., Cramb, S. M., Peters, S., Porceddu, S. V., Moller, H., Fritschi, L., et al. (2013). International comparisons of the incidence and mortality of sinonasal cancer. Cancer Epidemiology, 37(6), 770–779.PubMedCrossRef
16.
Zurück zum Zitat Lionello, M., Stritoni, P., Facciolo, M. C., Staffieri, A., Martini, A., Mazzoni, A., et al. (2014). Temporal bone carcinoma. Current diagnostic, therapeutic, and prognostic concepts. Journal of Surgical Oncology, 110(4), 383–392.PubMedCrossRef Lionello, M., Stritoni, P., Facciolo, M. C., Staffieri, A., Martini, A., Mazzoni, A., et al. (2014). Temporal bone carcinoma. Current diagnostic, therapeutic, and prognostic concepts. Journal of Surgical Oncology, 110(4), 383–392.PubMedCrossRef
17.
Zurück zum Zitat Bruce, J. P., Yip, K., Bratman, S. V., Ito, E., & Liu, F. F. (2015). Nasopharyngeal cancer: molecular landscape. Journal of Clinical Oncology, 33(29), 3346–3355.PubMedCrossRef Bruce, J. P., Yip, K., Bratman, S. V., Ito, E., & Liu, F. F. (2015). Nasopharyngeal cancer: molecular landscape. Journal of Clinical Oncology, 33(29), 3346–3355.PubMedCrossRef
18.
Zurück zum Zitat IARC Working Group. (2012). Consumption of alcoholic beverages. Lyon: International Agency for Research on Cancer. IARC Working Group. (2012). Consumption of alcoholic beverages. Lyon: International Agency for Research on Cancer.
19.
Zurück zum Zitat Seitz, H. K., & Stickel, F. (2007). Molecular mechanisms of alcohol-mediated carcinogenesis. Nature Reviews. Cancer, 7(8), 599–612.PubMedCrossRef Seitz, H. K., & Stickel, F. (2007). Molecular mechanisms of alcohol-mediated carcinogenesis. Nature Reviews. Cancer, 7(8), 599–612.PubMedCrossRef
20.
Zurück zum Zitat Garro, A. J., Espina, N., Farinati, F., & Salvagnini, M. (1986). The effects of chronic ethanol consumption on carcinogen metabolism and on O6-methylguanine transferase-mediated repair of alkylated DNA. Alcoholism, Clinical and Experimental Research, 10(6 Suppl), 73S–77S.PubMedCrossRef Garro, A. J., Espina, N., Farinati, F., & Salvagnini, M. (1986). The effects of chronic ethanol consumption on carcinogen metabolism and on O6-methylguanine transferase-mediated repair of alkylated DNA. Alcoholism, Clinical and Experimental Research, 10(6 Suppl), 73S–77S.PubMedCrossRef
21.
Zurück zum Zitat Seitz, H. K., & Stickel, F. (2006). Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress. Biological Chemistry, 387(4), 349–360.PubMedCrossRef Seitz, H. K., & Stickel, F. (2006). Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress. Biological Chemistry, 387(4), 349–360.PubMedCrossRef
22.
Zurück zum Zitat Matsuda, T., Kawanishi, M., Yagi, T., Matsui, S., & Takebe, H. (1998). Specific tandem GG to TT base substitutions induced by acetaldehyde are due to intra-strand crosslinks between adjacent guanine bases. Nucleic Acids Research, 26(7), 1769–1774.PubMedPubMedCentralCrossRef Matsuda, T., Kawanishi, M., Yagi, T., Matsui, S., & Takebe, H. (1998). Specific tandem GG to TT base substitutions induced by acetaldehyde are due to intra-strand crosslinks between adjacent guanine bases. Nucleic Acids Research, 26(7), 1769–1774.PubMedPubMedCentralCrossRef
23.
Zurück zum Zitat Wang, M., McIntee, E. J., Cheng, G., Shi, Y., Villalta, P. W., & Hecht, S. S. (2000). Identification of DNA adducts of acetaldehyde. Chemical Research in Toxicology, 13(11), 1149–1157.PubMedCrossRef Wang, M., McIntee, E. J., Cheng, G., Shi, Y., Villalta, P. W., & Hecht, S. S. (2000). Identification of DNA adducts of acetaldehyde. Chemical Research in Toxicology, 13(11), 1149–1157.PubMedCrossRef
24.
Zurück zum Zitat Theruvathu, J. A., Jaruga, P., Nath, R. G., Dizdaroglu, M., & Brooks, P. J. (2005). Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde. Nucleic Acids Research, 33(11), 3513–3520.PubMedPubMedCentralCrossRef Theruvathu, J. A., Jaruga, P., Nath, R. G., Dizdaroglu, M., & Brooks, P. J. (2005). Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde. Nucleic Acids Research, 33(11), 3513–3520.PubMedPubMedCentralCrossRef
25.
Zurück zum Zitat Wang, M., Yu, N., Chen, L., Villalta, P. W., Hochalter, J. B., & Hecht, S. S. (2006). Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine. Chemical Research in Toxicology, 19(2), 319–324.PubMedPubMedCentralCrossRef Wang, M., Yu, N., Chen, L., Villalta, P. W., Hochalter, J. B., & Hecht, S. S. (2006). Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine. Chemical Research in Toxicology, 19(2), 319–324.PubMedPubMedCentralCrossRef
26.
Zurück zum Zitat Homann, N., Jousimies-Somer, H., Jokelainen, K., Heine, R., & Salaspuro, M. (1997). High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications. Carcinogenesis, 18(9), 1739–1743.PubMedCrossRef Homann, N., Jousimies-Somer, H., Jokelainen, K., Heine, R., & Salaspuro, M. (1997). High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications. Carcinogenesis, 18(9), 1739–1743.PubMedCrossRef
27.
Zurück zum Zitat Homann, N., Tillonen, J., Meurman, J. H., Rintamaki, H., Lindqvist, C., Rautio, M., et al. (2000). Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer. Carcinogenesis, 21(4), 663–668.PubMedCrossRef Homann, N., Tillonen, J., Meurman, J. H., Rintamaki, H., Lindqvist, C., Rautio, M., et al. (2000). Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer. Carcinogenesis, 21(4), 663–668.PubMedCrossRef
28.
Zurück zum Zitat Wight, A. J., & Ogden, G. R. (1998). Possible mechanisms by which alcohol may influence the development of oral cancer—a review. Oral Oncology, 34(6), 441–447.PubMedCrossRef Wight, A. J., & Ogden, G. R. (1998). Possible mechanisms by which alcohol may influence the development of oral cancer—a review. Oral Oncology, 34(6), 441–447.PubMedCrossRef
29.
Zurück zum Zitat Boffetta, P., & Hashibe, M. (2006). Alcohol and cancer. The Lancet Oncology, 7(2), 149–156.PubMedCrossRef Boffetta, P., & Hashibe, M. (2006). Alcohol and cancer. The Lancet Oncology, 7(2), 149–156.PubMedCrossRef
30.
Zurück zum Zitat Hashibe, M., Brennan, P., Chuang, S. C., Boccia, S., Castellsague, X., Chen, C., et al. (2009). Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the international head and neck cancer epidemiology consortium. Cancer Epidemiology, Biomarkers & Prevention, 18(2), 541–550.CrossRef Hashibe, M., Brennan, P., Chuang, S. C., Boccia, S., Castellsague, X., Chen, C., et al. (2009). Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the international head and neck cancer epidemiology consortium. Cancer Epidemiology, Biomarkers & Prevention, 18(2), 541–550.CrossRef
31.
Zurück zum Zitat Cook, R. T. (1998). Alcohol abuse, alcoholism, and damage to the immune system—a review. Alcoholism, Clinical and Experimental Research, 22(9), 1927–1942.PubMed Cook, R. T. (1998). Alcohol abuse, alcoholism, and damage to the immune system—a review. Alcoholism, Clinical and Experimental Research, 22(9), 1927–1942.PubMed
32.
Zurück zum Zitat Bailey, L. B. (1990). Folate status assessment. The Journal of Nutrition, 120(Suppl 11), 1508–1511.PubMed Bailey, L. B. (1990). Folate status assessment. The Journal of Nutrition, 120(Suppl 11), 1508–1511.PubMed
33.
Zurück zum Zitat Barak, A. J., Beckenhauer, H. C., Tuma, D. J., & Badakhsh, S. (1987). Effects of prolonged ethanol feeding on methionine metabolism in rat liver. Biochemistry and Cell Biology, 65(3), 230–233.PubMedCrossRef Barak, A. J., Beckenhauer, H. C., Tuma, D. J., & Badakhsh, S. (1987). Effects of prolonged ethanol feeding on methionine metabolism in rat liver. Biochemistry and Cell Biology, 65(3), 230–233.PubMedCrossRef
34.
Zurück zum Zitat Mason, J. B., & Choi, S. W. (2005). Effects of alcohol on folate metabolism: implications for carcinogenesis. Alcohol, 35(3), 235–241.PubMedCrossRef Mason, J. B., & Choi, S. W. (2005). Effects of alcohol on folate metabolism: implications for carcinogenesis. Alcohol, 35(3), 235–241.PubMedCrossRef
35.
Zurück zum Zitat Shanmugham, J. R., Zavras, A. I., Rosner, B. A., & Giovannucci, E. L. (2010). Alcohol-folate interactions in the risk of oral cancer in women: a prospective cohort study. Cancer Epidemiology, Biomarkers & Prevention, 19(10), 2516–2524.CrossRef Shanmugham, J. R., Zavras, A. I., Rosner, B. A., & Giovannucci, E. L. (2010). Alcohol-folate interactions in the risk of oral cancer in women: a prospective cohort study. Cancer Epidemiology, Biomarkers & Prevention, 19(10), 2516–2524.CrossRef
36.
Zurück zum Zitat Matsuo, K., Rossi, M., Negri, E., Oze, I., Hosono, S., Ito, H., et al. (2012). Folate, alcohol, and aldehyde dehydrogenase 2 polymorphism and the risk of oral and pharyngeal cancer in Japanese. European Journal of Cancer Prevention, 21(2), 193–198.PubMedCrossRef Matsuo, K., Rossi, M., Negri, E., Oze, I., Hosono, S., Ito, H., et al. (2012). Folate, alcohol, and aldehyde dehydrogenase 2 polymorphism and the risk of oral and pharyngeal cancer in Japanese. European Journal of Cancer Prevention, 21(2), 193–198.PubMedCrossRef
37.
Zurück zum Zitat Galeone, C., Edefonti, V., Parpinel, M., Leoncini, E., Matsuo, K., Talamini, R., et al. (2015). Folate intake and the risk of oral cavity and pharyngeal cancer: a pooled analysis within the international head and neck cancer epidemiology consortium. International Journal of Cancer, 136(4), 904–914.PubMedCrossRef Galeone, C., Edefonti, V., Parpinel, M., Leoncini, E., Matsuo, K., Talamini, R., et al. (2015). Folate intake and the risk of oral cavity and pharyngeal cancer: a pooled analysis within the international head and neck cancer epidemiology consortium. International Journal of Cancer, 136(4), 904–914.PubMedCrossRef
38.
Zurück zum Zitat Brennan, P., Lewis, S., Hashibe, M., Bell, D. A., Boffetta, P., Bouchardy, C., et al. (2004). Pooled analysis of alcohol dehydrogenase genotypes and head and neck cancer: a HuGE review. American Journal of Epidemiology, 159(1), 1–16.PubMedCrossRef Brennan, P., Lewis, S., Hashibe, M., Bell, D. A., Boffetta, P., Bouchardy, C., et al. (2004). Pooled analysis of alcohol dehydrogenase genotypes and head and neck cancer: a HuGE review. American Journal of Epidemiology, 159(1), 1–16.PubMedCrossRef
39.
Zurück zum Zitat IARC Working Group. (2004). Tobacco smoke and involuntary smoking. Lyon: International Agency for Research on Cancer. IARC Working Group. (2004). Tobacco smoke and involuntary smoking. Lyon: International Agency for Research on Cancer.
40.
Zurück zum Zitat Winn, D. M., Lee, Y. C., Hashibe, M., & Boffetta, P. (2015). The INHANCE consortium: toward a better understanding of the causes and mechanisms of head and neck cancer. Oral Diseases, 21(6), 685–693.PubMedCrossRef Winn, D. M., Lee, Y. C., Hashibe, M., & Boffetta, P. (2015). The INHANCE consortium: toward a better understanding of the causes and mechanisms of head and neck cancer. Oral Diseases, 21(6), 685–693.PubMedCrossRef
41.
Zurück zum Zitat Lubin, J. H., Purdue, M., Kelsey, K., Zhang, Z. F., Winn, D., Wei, Q., et al. (2009). Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studies. American Journal of Epidemiology, 170(8), 937–947.PubMedPubMedCentralCrossRef Lubin, J. H., Purdue, M., Kelsey, K., Zhang, Z. F., Winn, D., Wei, Q., et al. (2009). Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studies. American Journal of Epidemiology, 170(8), 937–947.PubMedPubMedCentralCrossRef
42.
Zurück zum Zitat Altieri, A., Bosetti, C., Gallus, S., Franceschi, S., Dal Maso, L., Talamini, R., et al. (2004). Wine, beer and spirits and risk of oral and pharyngeal cancer: a case-control study from Italy and Switzerland. Oral Oncology, 40(9), 904–909.PubMedCrossRef Altieri, A., Bosetti, C., Gallus, S., Franceschi, S., Dal Maso, L., Talamini, R., et al. (2004). Wine, beer and spirits and risk of oral and pharyngeal cancer: a case-control study from Italy and Switzerland. Oral Oncology, 40(9), 904–909.PubMedCrossRef
43.
Zurück zum Zitat Garavello, W., Bosetti, C., Gallus, S., Maso, L. D., Negri, E., Franceschi, S., et al. (2006). Type of alcoholic beverage and the risk of laryngeal cancer. European Journal of Cancer Prevention, 15(1), 69–73.PubMedCrossRef Garavello, W., Bosetti, C., Gallus, S., Maso, L. D., Negri, E., Franceschi, S., et al. (2006). Type of alcoholic beverage and the risk of laryngeal cancer. European Journal of Cancer Prevention, 15(1), 69–73.PubMedCrossRef
44.
Zurück zum Zitat Purdue, M. P., Hashibe, M., Berthiller, J., La Vecchia, C., Dal Maso, L., Herrero, R., et al. (2009). Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE consortium. American Journal of Epidemiology, 169(2), 132–142.PubMedCrossRef Purdue, M. P., Hashibe, M., Berthiller, J., La Vecchia, C., Dal Maso, L., Herrero, R., et al. (2009). Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE consortium. American Journal of Epidemiology, 169(2), 132–142.PubMedCrossRef
45.
Zurück zum Zitat Altieri, A., Bosetti, C., Talamini, R., Gallus, S., Franceschi, S., Levi, F., et al. (2002). Cessation of smoking and drinking and the risk of laryngeal cancer. British Journal of Cancer, 87(11), 1227–1229.PubMedPubMedCentralCrossRef Altieri, A., Bosetti, C., Talamini, R., Gallus, S., Franceschi, S., Levi, F., et al. (2002). Cessation of smoking and drinking and the risk of laryngeal cancer. British Journal of Cancer, 87(11), 1227–1229.PubMedPubMedCentralCrossRef
46.
Zurück zum Zitat Franceschi, S., Levi, F., Dal Maso, L., Talamini, R., Conti, E., Negri, E., et al. (2000). Cessation of alcohol drinking and risk of cancer of the oral cavity and pharynx. International Journal of Cancer, 85(6), 787–790.PubMedCrossRef Franceschi, S., Levi, F., Dal Maso, L., Talamini, R., Conti, E., Negri, E., et al. (2000). Cessation of alcohol drinking and risk of cancer of the oral cavity and pharynx. International Journal of Cancer, 85(6), 787–790.PubMedCrossRef
47.
Zurück zum Zitat Marron, M., Boffetta, P., Zhang, Z. F., Zaridze, D., Wunsch-Filho, V., Winn, D. M., et al. (2010). Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk. International Journal of Epidemiology, 39(1), 182–196.PubMedCrossRef Marron, M., Boffetta, P., Zhang, Z. F., Zaridze, D., Wunsch-Filho, V., Winn, D. M., et al. (2010). Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk. International Journal of Epidemiology, 39(1), 182–196.PubMedCrossRef
48.
Zurück zum Zitat Rehm, J., Patra, J., & Popova, S. (2007). Alcohol drinking cessation and its effect on esophageal and head and neck cancers: a pooled analysis. International Journal of Cancer, 121(5), 1132–1137.PubMedCrossRef Rehm, J., Patra, J., & Popova, S. (2007). Alcohol drinking cessation and its effect on esophageal and head and neck cancers: a pooled analysis. International Journal of Cancer, 121(5), 1132–1137.PubMedCrossRef
49.
Zurück zum Zitat Ahmad Kiadaliri, A., Jarl, J., Gavriilidis, G., & Gerdtham, U. G. (2013). Alcohol drinking cessation and the risk of laryngeal and pharyngeal cancers: a systematic review and meta-analysis. PloS One, 8(3), e58158.PubMedPubMedCentralCrossRef Ahmad Kiadaliri, A., Jarl, J., Gavriilidis, G., & Gerdtham, U. G. (2013). Alcohol drinking cessation and the risk of laryngeal and pharyngeal cancers: a systematic review and meta-analysis. PloS One, 8(3), e58158.PubMedPubMedCentralCrossRef
50.
Zurück zum Zitat Osier, M. V., Pakstis, A. J., Soodyall, H., Comas, D., Goldman, D., Odunsi, A., et al. (2002). A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. American Journal of Human Genetics, 71(1), 84–99.PubMedPubMedCentralCrossRef Osier, M. V., Pakstis, A. J., Soodyall, H., Comas, D., Goldman, D., Odunsi, A., et al. (2002). A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. American Journal of Human Genetics, 71(1), 84–99.PubMedPubMedCentralCrossRef
51.
Zurück zum Zitat Bosron, W. F., & Li, T. K. (1986). Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology, 6(3), 502–510.PubMedCrossRef Bosron, W. F., & Li, T. K. (1986). Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology, 6(3), 502–510.PubMedCrossRef
52.
Zurück zum Zitat Hoog, J. O., Heden, L. O., Larsson, K., Jornvall, H., & von Bahr-Lindstrom, H. (1986). The gamma 1 and gamma 2 subunits of human liver alcohol dehydrogenase. cDNA structures, two amino acid replacements, and compatibility with changes in the enzymatic properties. European Journal of Biochemistry, 159(2), 215–218.PubMedCrossRef Hoog, J. O., Heden, L. O., Larsson, K., Jornvall, H., & von Bahr-Lindstrom, H. (1986). The gamma 1 and gamma 2 subunits of human liver alcohol dehydrogenase. cDNA structures, two amino acid replacements, and compatibility with changes in the enzymatic properties. European Journal of Biochemistry, 159(2), 215–218.PubMedCrossRef
53.
Zurück zum Zitat Yoshida, A., Huang, I. Y., & Ikawa, M. (1984). Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals. Proceedings of the National Academy of Sciences of the United States of America, 81(1), 258–261.PubMedPubMedCentralCrossRef Yoshida, A., Huang, I. Y., & Ikawa, M. (1984). Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals. Proceedings of the National Academy of Sciences of the United States of America, 81(1), 258–261.PubMedPubMedCentralCrossRef
54.
Zurück zum Zitat Osier, M., Pakstis, A. J., Kidd, J. R., Lee, J. F., Yin, S. J., Ko, H. C., et al. (1999). Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism. American Journal of Human Genetics, 64(4), 1147–1157.PubMedPubMedCentralCrossRef Osier, M., Pakstis, A. J., Kidd, J. R., Lee, J. F., Yin, S. J., Ko, H. C., et al. (1999). Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism. American Journal of Human Genetics, 64(4), 1147–1157.PubMedPubMedCentralCrossRef
55.
Zurück zum Zitat Enomoto, N., Takase, S., Yasuhara, M., & Takada, A. (1991). Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes. Alcoholism, Clinical and Experimental Research, 15(1), 141–144.PubMedCrossRef Enomoto, N., Takase, S., Yasuhara, M., & Takada, A. (1991). Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes. Alcoholism, Clinical and Experimental Research, 15(1), 141–144.PubMedCrossRef
56.
Zurück zum Zitat Quertemont, E. (2004). Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism. Molecular Psychiatry, 9(6), 570–581.PubMedCrossRef Quertemont, E. (2004). Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism. Molecular Psychiatry, 9(6), 570–581.PubMedCrossRef
57.
Zurück zum Zitat Roychoudhury, A. K., & N. M. (1988). Human polymorphic genes: world distributioned. New York: Oxford University Press. Roychoudhury, A. K., & N. M. (1988). Human polymorphic genes: world distributioned. New York: Oxford University Press.
58.
Zurück zum Zitat Chang, J. S., Straif, K., & Guha, N. (2012). The role of alcohol dehydrogenase genes in head and neck cancers: a systematic review and meta-analysis of ADH1B and ADH1C. Mutagenesis, 27(3), 275–286.PubMedCrossRef Chang, J. S., Straif, K., & Guha, N. (2012). The role of alcohol dehydrogenase genes in head and neck cancers: a systematic review and meta-analysis of ADH1B and ADH1C. Mutagenesis, 27(3), 275–286.PubMedCrossRef
59.
Zurück zum Zitat Boccia, S., Hashibe, M., Galli, P., De Feo, E., Asakage, T., Hashimoto, T., et al. (2009). Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mendelian randomization approach. Cancer Epidemiology, Biomarkers & Prevention, 18(1), 248–254.CrossRef Boccia, S., Hashibe, M., Galli, P., De Feo, E., Asakage, T., Hashimoto, T., et al. (2009). Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mendelian randomization approach. Cancer Epidemiology, Biomarkers & Prevention, 18(1), 248–254.CrossRef
60.
Zurück zum Zitat Katoh, T., Kaneko, S., Kohshi, K., Munaka, M., Kitagawa, K., Kunugita, N., et al. (1999). Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer. International Journal of Cancer, 83(5), 606–609.PubMedCrossRef Katoh, T., Kaneko, S., Kohshi, K., Munaka, M., Kitagawa, K., Kunugita, N., et al. (1999). Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer. International Journal of Cancer, 83(5), 606–609.PubMedCrossRef
61.
Zurück zum Zitat Nomura, T., Noma, H., Shibahara, T., Yokoyama, A., Muramatusu, T., & Ohmori, T. (2000). Aldehyde dehydrogenase 2 and glutathione S-transferase M 1 polymorphisms in relation to the risk for oral cancer in Japanese drinkers. Oral Oncology, 36(1), 42–46.PubMedCrossRef Nomura, T., Noma, H., Shibahara, T., Yokoyama, A., Muramatusu, T., & Ohmori, T. (2000). Aldehyde dehydrogenase 2 and glutathione S-transferase M 1 polymorphisms in relation to the risk for oral cancer in Japanese drinkers. Oral Oncology, 36(1), 42–46.PubMedCrossRef
62.
Zurück zum Zitat Yokoyama, A., Muramatsu, T., Omori, T., Yokoyama, T., Matsushita, S., Higuchi, S., et al. (2001). Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics. Carcinogenesis, 22(3), 433–439.PubMedCrossRef Yokoyama, A., Muramatsu, T., Omori, T., Yokoyama, T., Matsushita, S., Higuchi, S., et al. (2001). Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics. Carcinogenesis, 22(3), 433–439.PubMedCrossRef
63.
Zurück zum Zitat Hashimoto, T., Uchida, K., Okayama, N., Imate, Y., Suehiro, Y., Ueyama, Y., et al. (2006). ALDH2 1510 G/a (Glu487Lys) polymorphism interaction with age in head and neck squamous cell carcinoma. Tumour Biology, 27(6), 334–338.PubMedCrossRef Hashimoto, T., Uchida, K., Okayama, N., Imate, Y., Suehiro, Y., Ueyama, Y., et al. (2006). ALDH2 1510 G/a (Glu487Lys) polymorphism interaction with age in head and neck squamous cell carcinoma. Tumour Biology, 27(6), 334–338.PubMedCrossRef
64.
Zurück zum Zitat Asakage, T., Yokoyama, A., Haneda, T., Yamazaki, M., Muto, M., Yokoyama, T., et al. (2007). Genetic polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma. Carcinogenesis, 28(4), 865–874.PubMedCrossRef Asakage, T., Yokoyama, A., Haneda, T., Yamazaki, M., Muto, M., Yokoyama, T., et al. (2007). Genetic polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma. Carcinogenesis, 28(4), 865–874.PubMedCrossRef
65.
Zurück zum Zitat Hiraki, A., Matsuo, K., Wakai, K., Suzuki, T., Hasegawa, Y., & Tajima, K. (2007). Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan. Cancer Science, 98(7), 1087–1091.PubMedCrossRef Hiraki, A., Matsuo, K., Wakai, K., Suzuki, T., Hasegawa, Y., & Tajima, K. (2007). Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan. Cancer Science, 98(7), 1087–1091.PubMedCrossRef
66.
Zurück zum Zitat Mizoi, Y., Yamamoto, K., Ueno, Y., Fukunaga, T., & Harada, S. (1994). Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism. Alcohol and Alcoholism, 29(6), 707–710.PubMed Mizoi, Y., Yamamoto, K., Ueno, Y., Fukunaga, T., & Harada, S. (1994). Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism. Alcohol and Alcoholism, 29(6), 707–710.PubMed
67.
Zurück zum Zitat Hashibe, M., McKay, J. D., Curado, M. P., Oliveira, J. C., Koifman, S., Koifman, R., et al. (2008). Multiple ADH genes are associated with upper aerodigestive cancers. Nature Genetics, 40(6), 707–709.PubMedCrossRef Hashibe, M., McKay, J. D., Curado, M. P., Oliveira, J. C., Koifman, S., Koifman, R., et al. (2008). Multiple ADH genes are associated with upper aerodigestive cancers. Nature Genetics, 40(6), 707–709.PubMedCrossRef
68.
Zurück zum Zitat Wei, S., Liu, Z., Zhao, H., Niu, J., Wang, L. E., El-Naggar, A. K., et al. (2010). A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck. Cancer, 116(12), 2984–2992.PubMedPubMedCentralCrossRef Wei, S., Liu, Z., Zhao, H., Niu, J., Wang, L. E., El-Naggar, A. K., et al. (2010). A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck. Cancer, 116(12), 2984–2992.PubMedPubMedCentralCrossRef
69.
Zurück zum Zitat Oze, I., Matsuo, K., Suzuki, T., Kawase, T., Watanabe, M., Hiraki, A., et al. (2009). Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population. Cancer Epidemiology, Biomarkers & Prevention, 18(11), 3097–3102.CrossRef Oze, I., Matsuo, K., Suzuki, T., Kawase, T., Watanabe, M., Hiraki, A., et al. (2009). Impact of multiple alcohol dehydrogenase gene polymorphisms on risk of upper aerodigestive tract cancers in a Japanese population. Cancer Epidemiology, Biomarkers & Prevention, 18(11), 3097–3102.CrossRef
70.
Zurück zum Zitat Hung, H. C., Chuang, J., Chien, Y. C., Chern, H. D., Chiang, C. P., Kuo, Y. S., et al. (1997). Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer. Cancer Epidemiology, Biomarkers & Prevention, 6(11), 901–905. Hung, H. C., Chuang, J., Chien, Y. C., Chern, H. D., Chiang, C. P., Kuo, Y. S., et al. (1997). Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer. Cancer Epidemiology, Biomarkers & Prevention, 6(11), 901–905.
71.
Zurück zum Zitat Hayashi, S., Watanabe, J., & Kawajiri, K. (1991). Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene. Journal of Biochemistry, 110(4), 559–565.PubMedCrossRef Hayashi, S., Watanabe, J., & Kawajiri, K. (1991). Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene. Journal of Biochemistry, 110(4), 559–565.PubMedCrossRef
72.
Zurück zum Zitat Druesne-Pecollo, N., Tehard, B., Mallet, Y., Gerber, M., Norat, T., Hercberg, S., et al. (2009). Alcohol and genetic polymorphisms: effect on risk of alcohol-related cancer. The Lancet Oncology, 10(2), 173–180.PubMedCrossRef Druesne-Pecollo, N., Tehard, B., Mallet, Y., Gerber, M., Norat, T., Hercberg, S., et al. (2009). Alcohol and genetic polymorphisms: effect on risk of alcohol-related cancer. The Lancet Oncology, 10(2), 173–180.PubMedCrossRef
73.
Zurück zum Zitat Watanabe, J., Hayashi, S., & Kawajiri, K. (1994). Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region. Journal of Biochemistry, 116(2), 321–326.PubMedCrossRef Watanabe, J., Hayashi, S., & Kawajiri, K. (1994). Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region. Journal of Biochemistry, 116(2), 321–326.PubMedCrossRef
74.
Zurück zum Zitat Uematsu, F., Kikuchi, H., Motomiya, M., Abe, T., Sagami, I., Ohmachi, T., et al. (1991). Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer. Japanese Journal of Cancer Research, 82(3), 254–256.PubMedCrossRef Uematsu, F., Kikuchi, H., Motomiya, M., Abe, T., Sagami, I., Ohmachi, T., et al. (1991). Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer. Japanese Journal of Cancer Research, 82(3), 254–256.PubMedCrossRef
75.
Zurück zum Zitat Tsutsumi, M., Wang, J. S., Takase, S., & Takada, A. (1994). Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes. Alcohol and Alcoholism. Supplement, 29(1), 29–32. Tsutsumi, M., Wang, J. S., Takase, S., & Takada, A. (1994). Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes. Alcohol and Alcoholism. Supplement, 29(1), 29–32.
76.
Zurück zum Zitat Hildesheim, A., Anderson, L. M., Chen, C. J., Cheng, Y. J., Brinton, L. A., Daly, A. K., et al. (1997). CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan. Journal of the National Cancer Institute, 89(16), 1207–1212.PubMedCrossRef Hildesheim, A., Anderson, L. M., Chen, C. J., Cheng, Y. J., Brinton, L. A., Daly, A. K., et al. (1997). CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan. Journal of the National Cancer Institute, 89(16), 1207–1212.PubMedCrossRef
77.
Zurück zum Zitat Tang, K., Li, Y., Zhang, Z., Gu, Y., Xiong, Y., Feng, G., et al. (2010). The PstI/RsaI and DraI polymorphisms of CYP2E1 and head and neck cancer risk: a meta-analysis based on 21 case-control studies. BMC Cancer, 10, 575.PubMedPubMedCentralCrossRef Tang, K., Li, Y., Zhang, Z., Gu, Y., Xiong, Y., Feng, G., et al. (2010). The PstI/RsaI and DraI polymorphisms of CYP2E1 and head and neck cancer risk: a meta-analysis based on 21 case-control studies. BMC Cancer, 10, 575.PubMedPubMedCentralCrossRef
78.
Zurück zum Zitat Garte, S., Gaspari, L., Alexandrie, A. K., Ambrosone, C., Autrup, H., Autrup, J. L., et al. (2001). Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiology, Biomarkers & Prevention, 10(12), 1239–1248. Garte, S., Gaspari, L., Alexandrie, A. K., Ambrosone, C., Autrup, H., Autrup, J. L., et al. (2001). Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiology, Biomarkers & Prevention, 10(12), 1239–1248.
79.
Zurück zum Zitat McKay, J. D., Truong, T., Gaborieau, V., Chabrier, A., Chuang, S. C., Byrnes, G., et al. (2011). A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genetics, 7(3), e1001333.PubMedPubMedCentralCrossRef McKay, J. D., Truong, T., Gaborieau, V., Chabrier, A., Chuang, S. C., Byrnes, G., et al. (2011). A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genetics, 7(3), e1001333.PubMedPubMedCentralCrossRef
80.
Zurück zum Zitat Delahaye-Sourdeix, M., Anantharaman, D., Timofeeva, M. N., Gaborieau, V., Chabrier, A., Vallee, M. P., et al. (2015). A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer. Journal of the National Cancer Institute, 107(5). doi:10.1093/jnci/djv037. Delahaye-Sourdeix, M., Anantharaman, D., Timofeeva, M. N., Gaborieau, V., Chabrier, A., Vallee, M. P., et al. (2015). A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer. Journal of the National Cancer Institute, 107(5). doi:10.​1093/​jnci/​djv037.
81.
Zurück zum Zitat Leclerc, D., Campeau, E., Goyette, P., Adjalla, C. E., Christensen, B., Ross, M., et al. (1996). Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Human Molecular Genetics, 5(12), 1867–1874.PubMedCrossRef Leclerc, D., Campeau, E., Goyette, P., Adjalla, C. E., Christensen, B., Ross, M., et al. (1996). Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Human Molecular Genetics, 5(12), 1867–1874.PubMedCrossRef
82.
Zurück zum Zitat Rozen, R. (1997). Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR). Thrombosis and Haemostasis, 78(1), 523–526.PubMed Rozen, R. (1997). Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR). Thrombosis and Haemostasis, 78(1), 523–526.PubMed
83.
Zurück zum Zitat Zhuo, X., Song, J., Li, D., Wu, Y., & Zhou, Q. (2015). MTHFR C677T polymorphism interaction with heavy alcohol consumption increases head and neck carcinoma risk. Scientific Reports, 5, 10671.PubMedPubMedCentralCrossRef Zhuo, X., Song, J., Li, D., Wu, Y., & Zhou, Q. (2015). MTHFR C677T polymorphism interaction with heavy alcohol consumption increases head and neck carcinoma risk. Scientific Reports, 5, 10671.PubMedPubMedCentralCrossRef
84.
Zurück zum Zitat Zhuo, X., Ling, J., Zhou, Y., Zhao, H., Song, Y., & Tan, Y. (2012). Polymorphisms of MTHFR C677T and A1298C association with oral carcinoma risk: a meta-analysis. Cancer Investigation, 30(6), 447–452.PubMedCrossRef Zhuo, X., Ling, J., Zhou, Y., Zhao, H., Song, Y., & Tan, Y. (2012). Polymorphisms of MTHFR C677T and A1298C association with oral carcinoma risk: a meta-analysis. Cancer Investigation, 30(6), 447–452.PubMedCrossRef
85.
Zurück zum Zitat Stevens, M. H., Gardner, J. W., Parkin, J. L., & Johnson, L. P. (1983). Head and neck cancer survival and life-style change. Archives of Otolaryngology, 109(11), 746–749.PubMedCrossRef Stevens, M. H., Gardner, J. W., Parkin, J. L., & Johnson, L. P. (1983). Head and neck cancer survival and life-style change. Archives of Otolaryngology, 109(11), 746–749.PubMedCrossRef
86.
Zurück zum Zitat Crosignani, P., Russo, A., Tagliabue, G., & Berrino, F. (1996). Tobacco and diet as determinants of survival in male laryngeal cancer patients. International Journal of Cancer, 65(3), 308–313.PubMedCrossRef Crosignani, P., Russo, A., Tagliabue, G., & Berrino, F. (1996). Tobacco and diet as determinants of survival in male laryngeal cancer patients. International Journal of Cancer, 65(3), 308–313.PubMedCrossRef
87.
Zurück zum Zitat Duffy, S. A., Ronis, D. L., McLean, S., Fowler, K. E., Gruber, S. B., Wolf, G. T., et al. (2009). Pretreatment health behaviors predict survival among patients with head and neck squamous cell carcinoma. Journal of Clinical Oncology, 27(12), 1969–1975.PubMedPubMedCentralCrossRef Duffy, S. A., Ronis, D. L., McLean, S., Fowler, K. E., Gruber, S. B., Wolf, G. T., et al. (2009). Pretreatment health behaviors predict survival among patients with head and neck squamous cell carcinoma. Journal of Clinical Oncology, 27(12), 1969–1975.PubMedPubMedCentralCrossRef
88.
Zurück zum Zitat Deleyiannis, F. W., Thomas, D. B., Vaughan, T. L., & Davis, S. (1996). Alcoholism: independent predictor of survival in patients with head and neck cancer. Journal of the National Cancer Institute, 88(8), 542–549.PubMedCrossRef Deleyiannis, F. W., Thomas, D. B., Vaughan, T. L., & Davis, S. (1996). Alcoholism: independent predictor of survival in patients with head and neck cancer. Journal of the National Cancer Institute, 88(8), 542–549.PubMedCrossRef
89.
Zurück zum Zitat Dikshit, R. P., Boffetta, P., Bouchardy, C., Merletti, F., Crosignani, P., Cuchi, T., et al. (2005). Lifestyle habits as prognostic factors in survival of laryngeal and hypopharyngeal cancer: a multicentric European study. International Journal of Cancer, 117(6), 992–995.PubMedCrossRef Dikshit, R. P., Boffetta, P., Bouchardy, C., Merletti, F., Crosignani, P., Cuchi, T., et al. (2005). Lifestyle habits as prognostic factors in survival of laryngeal and hypopharyngeal cancer: a multicentric European study. International Journal of Cancer, 117(6), 992–995.PubMedCrossRef
90.
Zurück zum Zitat Park, S. M., Lim, M. K., Shin, S. A., & Yun, Y. H. (2006). Impact of prediagnosis smoking, alcohol, obesity, and insulin resistance on survival in male cancer patients: National Health Insurance Corporation Study. Journal of Clinical Oncology, 24(31), 5017–5024.PubMedCrossRef Park, S. M., Lim, M. K., Shin, S. A., & Yun, Y. H. (2006). Impact of prediagnosis smoking, alcohol, obesity, and insulin resistance on survival in male cancer patients: National Health Insurance Corporation Study. Journal of Clinical Oncology, 24(31), 5017–5024.PubMedCrossRef
91.
Zurück zum Zitat Ide, R., Mizoue, T., Fujino, Y., Hoshiyama, Y., Sakata, K., Tamakoshi, A., et al. (2008). Cigarette smoking, alcohol drinking, and oral and pharyngeal cancer mortality in Japan. Oral Diseases, 14(4), 314–319.PubMedCrossRef Ide, R., Mizoue, T., Fujino, Y., Hoshiyama, Y., Sakata, K., Tamakoshi, A., et al. (2008). Cigarette smoking, alcohol drinking, and oral and pharyngeal cancer mortality in Japan. Oral Diseases, 14(4), 314–319.PubMedCrossRef
92.
Zurück zum Zitat Li, Y., Mao, Y., Zhang, Y., Cai, S., Chen, G., Ding, Y., et al. (2014). Alcohol drinking and upper aerodigestive tract cancer mortality: a systematic review and meta-analysis. Oral Oncology, 50(4), 269–275.PubMedCrossRef Li, Y., Mao, Y., Zhang, Y., Cai, S., Chen, G., Ding, Y., et al. (2014). Alcohol drinking and upper aerodigestive tract cancer mortality: a systematic review and meta-analysis. Oral Oncology, 50(4), 269–275.PubMedCrossRef
93.
Zurück zum Zitat Fortin, A., Wang, C. S., & Vigneault, E. (2009). Influence of smoking and alcohol drinking behaviors on treatment outcomes of patients with squamous cell carcinomas of the head and neck. International Journal of Radiation Oncology, Biology, Physics, 74(4), 1062–1069.PubMedCrossRef Fortin, A., Wang, C. S., & Vigneault, E. (2009). Influence of smoking and alcohol drinking behaviors on treatment outcomes of patients with squamous cell carcinomas of the head and neck. International Journal of Radiation Oncology, Biology, Physics, 74(4), 1062–1069.PubMedCrossRef
94.
Zurück zum Zitat Sawabe, M., Ito, H., Oze, I., Hosono, S., Kawakita, D., Tanaka, H., et al. (2017). Heterogeneous impact of drinking according to treatment method on survival in head and neck cancer: a prospective study. Cancer Science, 108(1), 91–100.PubMedPubMedCentralCrossRef Sawabe, M., Ito, H., Oze, I., Hosono, S., Kawakita, D., Tanaka, H., et al. (2017). Heterogeneous impact of drinking according to treatment method on survival in head and neck cancer: a prospective study. Cancer Science, 108(1), 91–100.PubMedPubMedCentralCrossRef
95.
Zurück zum Zitat Kawakita, D., Oze, I., Hosono, S., Ito, H., Watanabe, M., Yatabe, Y., et al. (2016). Prognostic value of drinking status and aldehyde dehydrogenase 2 polymorphism in patients with head and neck squamous cell carcinoma. Journal of Epidemiology, 26(6), 292–299.PubMedCrossRef Kawakita, D., Oze, I., Hosono, S., Ito, H., Watanabe, M., Yatabe, Y., et al. (2016). Prognostic value of drinking status and aldehyde dehydrogenase 2 polymorphism in patients with head and neck squamous cell carcinoma. Journal of Epidemiology, 26(6), 292–299.PubMedCrossRef
96.
Zurück zum Zitat Farshadpour, F., Kranenborg, H., Calkoen, E. V., Hordijk, G. J., Koole, R., Slootweg, P. J., et al. (2011). Survival analysis of head and neck squamous cell carcinoma: influence of smoking and drinking. Head & Neck, 33(6), 817–823.CrossRef Farshadpour, F., Kranenborg, H., Calkoen, E. V., Hordijk, G. J., Koole, R., Slootweg, P. J., et al. (2011). Survival analysis of head and neck squamous cell carcinoma: influence of smoking and drinking. Head & Neck, 33(6), 817–823.CrossRef
97.
Zurück zum Zitat Corrao, G., Bagnardi, V., Zambon, A., & Torchio, P. (1998). Meta-analysis of alcohol intake in relation to risk of liver cirrhosis. Alcohol and Alcoholism, 33(4), 381–392.PubMedCrossRef Corrao, G., Bagnardi, V., Zambon, A., & Torchio, P. (1998). Meta-analysis of alcohol intake in relation to risk of liver cirrhosis. Alcohol and Alcoholism, 33(4), 381–392.PubMedCrossRef
98.
Zurück zum Zitat Corrao, G., Rubbiati, L., Bagnardi, V., Zambon, A., & Poikolainen, K. (2000). Alcohol and coronary heart disease: a meta-analysis. Addiction, 95(10), 1505–1523.PubMedCrossRef Corrao, G., Rubbiati, L., Bagnardi, V., Zambon, A., & Poikolainen, K. (2000). Alcohol and coronary heart disease: a meta-analysis. Addiction, 95(10), 1505–1523.PubMedCrossRef
99.
Zurück zum Zitat Reynolds, K., Lewis, B., Nolen, J. D., Kinney, G. L., Sathya, B., & He, J. (2003). Alcohol consumption and risk of stroke: a meta-analysis. JAMA, 289(5), 579–588.PubMedCrossRef Reynolds, K., Lewis, B., Nolen, J. D., Kinney, G. L., Sathya, B., & He, J. (2003). Alcohol consumption and risk of stroke: a meta-analysis. JAMA, 289(5), 579–588.PubMedCrossRef
100.
Zurück zum Zitat Rose, B. S., Jeong, J. H., Nath, S. K., Lu, S. M., & Mell, L. K. (2011). Population-based study of competing mortality in head and neck cancer. Journal of Clinical Oncology, 29(26), 3503–3509.PubMedCrossRef Rose, B. S., Jeong, J. H., Nath, S. K., Lu, S. M., & Mell, L. K. (2011). Population-based study of competing mortality in head and neck cancer. Journal of Clinical Oncology, 29(26), 3503–3509.PubMedCrossRef
101.
Zurück zum Zitat Baxi, S. S., Pinheiro, L. C., Patil, S. M., Pfister, D. G., Oeffinger, K. C., & Elkin, E. B. (2014). Causes of death in long-term survivors of head and neck cancer. Cancer, 120(10), 1507–1513.PubMedPubMedCentralCrossRef Baxi, S. S., Pinheiro, L. C., Patil, S. M., Pfister, D. G., Oeffinger, K. C., & Elkin, E. B. (2014). Causes of death in long-term survivors of head and neck cancer. Cancer, 120(10), 1507–1513.PubMedPubMedCentralCrossRef
102.
Zurück zum Zitat Shen, W., Sakamoto, N., & Yang, L. (2015). Cancer-specific mortality and competing mortality in patients with head and neck squamous cell carcinoma: a competing risk analysis. Annals of Surgical Oncology, 22(1), 264–271.PubMedCrossRef Shen, W., Sakamoto, N., & Yang, L. (2015). Cancer-specific mortality and competing mortality in patients with head and neck squamous cell carcinoma: a competing risk analysis. Annals of Surgical Oncology, 22(1), 264–271.PubMedCrossRef
103.
Zurück zum Zitat Massa, S. T., Osazuwa-Peters, N., Christopher, K. M., Arnold, L. D., Schootman, M., Walker, R. J., et al. (2017). Competing causes of death in the head and neck cancer population. Oral Oncology, 65, 8–15.PubMedCrossRef Massa, S. T., Osazuwa-Peters, N., Christopher, K. M., Arnold, L. D., Schootman, M., Walker, R. J., et al. (2017). Competing causes of death in the head and neck cancer population. Oral Oncology, 65, 8–15.PubMedCrossRef
Metadaten
Titel
Alcohol and head and neck cancer
verfasst von
Daisuke Kawakita
Keitaro Matsuo
Publikationsdatum
16.08.2017
Verlag
Springer US
Erschienen in
Cancer and Metastasis Reviews / Ausgabe 3/2017
Print ISSN: 0167-7659
Elektronische ISSN: 1573-7233
DOI
https://doi.org/10.1007/s10555-017-9690-0

Weitere Artikel der Ausgabe 3/2017

Cancer and Metastasis Reviews 3/2017 Zur Ausgabe

OriginalPaper

Preface

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.