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Erschienen in: HNO 5/2022

28.03.2022 | Allergologie in der HNO-Heilkunde | Leitthema

Allergische Reaktionen auf Bioimplantate

verfasst von: Prof. Dr. med. L. Klimek

Erschienen in: HNO | Ausgabe 5/2022

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Zusammenfassung

Hintergrund

Bioimplantate werden im HNO-Bereich vielfältig eingesetzt, am häufigsten in der rekonstruktiven Gesichtschirurgie, bei Cochleaimplantaten (CI), knochenverankerten Hörgeräten, PORP/TORP-Prothesen („partial ossicular replacement prosthesis“, „total ossicular replacement prosthesis“), aber auch u. a. bei Paukendrainagen, Larynxkanülen, Stimmprothesen nach Laryngektomie und auch bei „HNO-nahen“ Eingriffen als dentale Implantate in der Zahnmedizin.

Methoden

In einer Literatursuche wurde die Immunologie allergischer Reaktionen auf Bioimplantate analysiert und die vorhandene Evidenz ermittelt durch Recherchen in den Datenbanken Medline, PubMed sowie den nationalen und internationalen Studien- und Leitlinienregistern und der Cochrane Library. Es wurden Humanstudien berücksichtigt, die im Zeitraum bis einschließlich 12/2021 publiziert wurden.

Ergebnis

Basierend auf der internationalen Literatur und bisheriger Erfahrungen wird eine Übersicht über Allergien auf Bioimplantate in der HNO-Heilkunde gegeben.

Schlussfolgerungen

HNO-Ärzte sollten bei Einbringen allogener Materialien immer auch an die Möglichkeit allergischer Reaktionen denken – insbesondere auch, aber nicht nur – bei Bioimplantaten.
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Metadaten
Titel
Allergische Reaktionen auf Bioimplantate
verfasst von
Prof. Dr. med. L. Klimek
Publikationsdatum
28.03.2022
Verlag
Springer Medizin
Erschienen in
HNO / Ausgabe 5/2022
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI
https://doi.org/10.1007/s00106-022-01173-x

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