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Erschienen in:

02.10.2023 | Review

Alteration in Gut Microbiota Composition of Older Adults Is Associated with Obesity and Its Indices: A Systematic Review

verfasst von: Z. Hoseini Tavassol, H.-S. Ejtahed, R. Atlasi, F. Saghafian, K. Khalagi, Shirin Hasani-Ranjbar, S. D. Siadat, I. Nabipour, A. Ostovar, B. Larijani

Erschienen in: The journal of nutrition, health & aging | Ausgabe 10/2023

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Abstract

Background

Obesity in the older adults is a health concern that increases the risk of several life-threatening diseases. Previous research has been revealed that alterations in the gut microbiota composition is related to obesity. So, understanding the gut microbiota changes in older adults’ obesity may help to provide promising strategies for their health management.

Objectives

Here we conducted a systematic review that investigate the alteration of gut microbiota composition in association with obesity and its indices in the older adults.

Design

Systematic review.

Setting

A comprehensive systematic search was performed through PubMed, Web of Science, Scopus and Embase databases for all relative studies up to 2023 with the main search concepts as Microbiota, Obesity and Elderly. The data about gut microbiota in association with obesity indices had been extracted.

Participants

Older adults (≥60 years).

Intervention

None.

Measurements

None.

Results

Within 10741 recordes, 11 studies met the inclusion criteria and were included in this systematic review. Most of them indicated the gut microbiota alterations in obese compared with non-obese older adults. However, the gut microbiome composition in obese older adults is affected by other underlying diseases like diabetes and metabolic syndrome. The most important taxa that had abundance alteration in association with obesity in older adults were Christensenellaceae, Porphyromonadaceae and Rikenellaceae, Akkermansia, Blautia, Prevotella, Ruminococcus, Bacteroides and Faecalibacterium.

Conclusion

The gut microbiota composition is associated with obesity in older adults. Considering the other factors affecting the composition of gut microbiota, such as age, underlying diseases and lifestyle, a more accurate conclusion about this matter requires more future studies.
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Metadaten
Titel
Alteration in Gut Microbiota Composition of Older Adults Is Associated with Obesity and Its Indices: A Systematic Review
verfasst von
Z. Hoseini Tavassol
H.-S. Ejtahed
R. Atlasi
F. Saghafian
K. Khalagi
Shirin Hasani-Ranjbar
S. D. Siadat
I. Nabipour
A. Ostovar
B. Larijani
Publikationsdatum
02.10.2023
Verlag
Springer Paris
Erschienen in
The journal of nutrition, health & aging / Ausgabe 10/2023
Print ISSN: 1279-7707
Elektronische ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-023-1988-8

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