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04.06.2017 | Original Article

aMMP-8 in correlation to caries and periodontal condition in adolescents—results of the epidemiologic LIFE child study

verfasst von: Jana Schmidt, Ulrike Guder, Markus Kreuz, Markus Löffler, Wieland Kiess, Christian Hirsch, Dirk Ziebolz, Rainer Haak

Erschienen in: Clinical Oral Investigations | Ausgabe 1/2018

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Abstract

Objectives

The suitability of a chairside aMMP-8 test in determination of periodontal inflammation and caries in adolescents was assessed. Secondly, the influence of orthodontic treatment on aMMP-8 test result was analyzed.

Materials and methods

Within the LIFE Child study, 434 adolescents (10 to 18 years) were included. Clinical dental examinations comprised caries experience (DMF/T-Index), signs of periodontal inflammation (probing pocket depth, PPD; community periodontal index of treatment needs; CPITN) at six index teeth and oral hygiene (OH). Information about orthodontic appliances (OA) and socioeconomic status (SES) were obtained by validated questionnaires. Test’s sensitivity and specificity to detect periodontal inflammation and carious lesions were evaluated. The influence of OA on the test result was analyzed (multivariate model).

Results

No associations between age, gender, SES or OH, and test outcome were found (p > 0.05). Positive test results correlated to periodontal findings (CPITN, mean PPD; p < 0.001). However, for the detection of ≥ 1 site(s) with PPD ≥ 4 mm, the test’s sensitivity and specificity were found to be 61 and 69%, respectively. Multivariate analysis revealed a higher probability for a positive test result in cases of fixed OA (odds ratio 5.02, 95% confidence interval 1.90–13.19). The test had no diagnostic value considering carious lesions.

Conclusions

The chairside aMMP-8 test does not reliably identify adolescents with periodontal inflammation. Positive test results were more frequent in case of OA.

Clinical relevance

The chairside aMMP-8 test is no appropriate tool to screen children and adolescents neither for periodontal inflammation nor for carious lesions.

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Titel: aMMP-8 in correlation to caries and periodontal condition in adolescents—results of the epidemiologic LIFE child study
verfasst von: Jana Schmidt
Ulrike Guder
Markus Kreuz
Markus Löffler
Wieland Kiess
Christian Hirsch
Dirk Ziebolz
Rainer Haak
Publikationsdatum: 04.06.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 1/2018
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-017-2132-0

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aMMP-8 in correlation to caries and periodontal condition in adolescents—results of the epidemiologic LIFE child study

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

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Springer Medizin

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

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