Erschienen in:
31.01.2017 | Original Article
Amount of smoking, pulmonary function, and bone mineral density in middle-aged Korean men: KNHANES 2008–2011
verfasst von:
Ji Hyun Lee, A Ram Hong, Jung Hee Kim, Kyoung Min Kim, Bo Kyung Koo, Chan Soo Shin, Sang Wan Kim
Erschienen in:
Journal of Bone and Mineral Metabolism
|
Ausgabe 1/2018
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Abstract
Smoking induces bone loss; however, data on the relationship between smoking history and bone mineral density (BMD) are lacking. Age and pulmonary function can affect BMD. We investigated the relationships among pack-years (PYs) of smoking, pulmonary function, and BMD in middle-aged Korean men (50–64 years old). This cross-sectional study used data from the Korean National Health and Nutrition Examination Survey, 2008–2011. All participants underwent BMD measurements using dual energy X-ray absorptiometry and pulmonary function tests using standardized spirometry. In total, 388 never-smokers and 1088 ever-smokers were analyzed. The number of PYs of smoking was negatively correlated with total hip BMD (r = −0.088; P = 0.004) after adjusting for age, height, and weight. Ever-smokers were classified into 3 groups according to PYs of smoking. The highest tertile (n = 482) exhibited significantly lower total hip bone mass than the lowest tertile (n = 214) after adjusting for confounding factors (age, height, weight, forced expiratory volume in 1 s (FEV1), alcohol consumption, physical activity, and vitamin D levels) that could affect bone metabolism (P = 0.003). In conclusion, smoking for >30 PYs was significantly associated with low hip BMD after adjusting for pulmonary function in middle-aged Korean men. Long-term smoking may be a risk factor for bone loss in middle-aged men independent of age, height, weight, and pulmonary function.