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Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases 3/2019

24.01.2019 | Original Article

An outbreak of leptospirosis among reserve military recruits, Hulu Perdik, Malaysia

verfasst von: Vasantha Kumari Neela, Nurul Natasya Azhari, Narcisse Joseph, Noraini Philip Mimie, Siti Nur Alia Ramli, Nooreen Farzana Mustapha, Siti Nabilah Ishak, Farah Shafawati Mohd-Taib, Muhammad Afif Yusof, Mohd Nasir Mohd Desa, Garba Bashiru, Zamberi Sekawi

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 3/2019

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Abstract

Here, we investigated an outbreak of leptospirosis among reserve military recruits that occurred following a survival exercise in the Hulu Perdik forest within the Hulu Langat district, Kuala Lumpur, Malaysia. Blood samples from the 12 patients that presented symptoms for febrile illness on clinical examination were subjected to laboratory investigation, comprising Lepto IgM rapid test, IgM ELISA, and microscopic agglutination test (MAT). All these patients were interviewed for possible risk factors for leptospirosis. Rodent trapping and environmental sampling for possible isolation of leptospires in the outbreak site was performed. The isolated leptospires were genetically characterized and investigated for the potential epidemiological link with human leptospirosis. Among the 12 patients, two (2/12; 16.6%) were confirmed positive for leptospirosis by microscopic agglutination test (MAT with titers 400–800; serovar autumnalis and hardjobovis). Two Leptospira species from rodents (L. interrogans and L. borgpetersenii) and two from the environment (L. kmetyi and L. wolffii) were identified. The possible epidemiological link between human serovars and animal Leptospira species indicates rodents as the potential reservoir while the environment (soil and water) serves as a transmission route. This investigation highlights the robust presence of pathogenic leptospires on Malaysian environment and rodents which may present the risk of infection, especially among high-risk individuals. Hence, occupational risk individuals are cautioned to observe appropriate preventive measures including prophylaxis and seek immediate medical attention for any illness following similar activities.
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Metadaten
Titel
An outbreak of leptospirosis among reserve military recruits, Hulu Perdik, Malaysia
verfasst von
Vasantha Kumari Neela
Nurul Natasya Azhari
Narcisse Joseph
Noraini Philip Mimie
Siti Nur Alia Ramli
Nooreen Farzana Mustapha
Siti Nabilah Ishak
Farah Shafawati Mohd-Taib
Muhammad Afif Yusof
Mohd Nasir Mohd Desa
Garba Bashiru
Zamberi Sekawi
Publikationsdatum
24.01.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 3/2019
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-018-03450-6

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