Erschienen in:
01.09.2018 | Neuroanesthesia (D Sharma, Section Editor)
An Update on Postoperative Delirium: Clinical Features,
Neuropathogenesis, and Perioperative Management
verfasst von:
Seyed A. Safavynia, Sona Arora, Kane O. Pryor, Paul S. García
Erschienen in:
Current Anesthesiology Reports
|
Ausgabe 3/2018
Einloggen, um Zugang zu erhalten
Abstract
Purpose of Review
We present a focused review on postoperative delirium for
anesthesiologists, encompassing clinical features, neuropathogenesis, and
clinical identification and management strategies based on risk factors and
current delirium treatments.
Recent Findings
The literature on postoperative delirium is dominated by
non-experimental studies. We review delirium phenotypes, diagnostic criteria,
and present standard nomenclature based on current literature. Disruption of
cortical integration of complex information (CICI) may provide a framework to
understand the neuropathogenesis of postoperative delirium, as well as risk
factors and clinical modifiers in the perioperative period. We further divide
risk factors into patient factors, surgical factors, and medical/pharmacological
factors, and present specific considerations for each in the preoperative,
intraoperative, and postoperative periods.
Summary
Postoperative delirium is prevalent, poorly understood, and often
missed with routine clinical care. Proper identification of risk factors is
useful for perioperative interventions and can help tailor patient-specific
management strategies.