Analgesic Efficacy of External Oblique Intercostal Block in Laparoscopic Sleeve Gastrectomy: A Systematic Review and Meta-Analysis
- 21.10.2025
- Research
Erschienen in:
- Verfasst von
- Burhan Dost
- Yunus Emre Karapinar
- Esra Turunc
- Muzeyyen Beldagli
- Cengiz Kaya
- Yasemin Burcu Ustun
- Ersin Koksal
- Alessandro De Cassai
- Erschienen in
- Obesity Surgery | Ausgabe 12/2025
Abstract
Background
Laparoscopic sleeve gastrectomy (LSG) is associated with significant postoperative pain despite being minimally invasive. External oblique intercostal block (EOIB) has emerged as a novel regional anesthesia technique targeting upper abdominal wall innervation. In this systematic review and meta-analysis with trial sequential analysis (TSA), we aimed to systematically assess the analgesic efficacy of EOIB in patients undergoing LSG, focusing on opioid consumption, pain scores, rescue analgesia use, and recovery outcomes.
Methods
We systematically searched PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, and Web of Science (from inception to until 22 May 2025). The primary outcome was 24-h opioid consumption. Secondary outcomes included pain scores, postoperative nausea and vomiting (PONV), and rescue analgesic use. Risk of bias was assessed using RoB 2, and the certainty of evidence was evaluated using the GRADE approach.
Results
Four RCTs (n = 249) were included. EOIB significantly reduced 24-h morphine milligram equivalent (MME) consumption (MD − 12.76 mg; 95% CI − 16.76 to − 8.77; p < 0.001). EOIB also lowered postoperative pain scores and decreased rescue analgesic use (OR 0.20; 95% CI 0.09–0.45). PONV incidence was reduced, but not statistically significant. TSA demonstrated that the current evidence is sufficient to confirm a statistically significant effect, with no further trials required.
Conclusions
EOIB appears to be a safe and effective component of multimodal analgesia in LSG, with TSA results supporting the robustness of current evidence.
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- Titel
- Analgesic Efficacy of External Oblique Intercostal Block in Laparoscopic Sleeve Gastrectomy: A Systematic Review and Meta-Analysis
- Verfasst von
-
Burhan Dost
Yunus Emre Karapinar
Esra Turunc
Muzeyyen Beldagli
Cengiz Kaya
Yasemin Burcu Ustun
Ersin Koksal
Alessandro De Cassai
- Publikationsdatum
- 21.10.2025
- Verlag
- Springer US
- Erschienen in
-
Obesity Surgery / Ausgabe 12/2025
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428 - DOI
- https://doi.org/10.1007/s11695-025-08270-0
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