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17.10.2019 | Brief Report

Analysis of bovine leukemia virus integration sites in cattle under 3 years old with enzootic bovine leukosis

verfasst von: Masaki Maezawa, Hisashi Inokuma

Erschienen in: Archives of Virology | Ausgabe 1/2020

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Abstract

In the present study, we analyzed bovine leukemia virus (BLV) integration sites in under 3 years old with enzootic bovine leukosis (EBL) cattle and compared these to 30 cattle over 3 years old with EBL. BLV proviruses were integrated near CpG islands and into long interspersed nuclear elements more frequently in EBL cattle under 3 years old than in those over 3 years old. These results suggest that cattle under 3 years old with EBL have different BLV provirus integration sites from those of cattle over 3 years old with EBL, and the BLV provirus integration site may represent one factor contributing to early onset of EBL.

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Titel: Analysis of bovine leukemia virus integration sites in cattle under 3 years old with enzootic bovine leukosis
verfasst von: Masaki Maezawa
Hisashi Inokuma
Publikationsdatum: 17.10.2019
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 1/2020
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-019-04431-6

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