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Graefe's Archive for Clinical and Experimental Ophthalmology

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10.02.2020 | Retinal Disorders

Analysis of choroidal thickness and vascularity in patients with unilateral polypoidal choroidal vasculopathy

verfasst von: Kook Lee, Jin-Heung Park, Young Gun Park, Young-Hoon Park

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 6/2020

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Abstract

Purpose

This study aimed to analyze the choroidal characteristics in eyes with polypoidal choroidal vasculopathy (PCV, affected eyes) and unaffected fellow eyes, and investigated the longitudinal changes in the choroidal structure of fellow eyes in patients with unilateral PCV.

Methods

We retrospectively reviewed the medical records of 55 treatment-naïve patients with unilateral PCV. The choroidal thickness and vascularity between PCV affected eyes, unaffected fellow eyes, and normal control eyes were compared. Structural changes in the choroid of the fellow eyes were reviewed during follow-up.

Results

PCV eyes had thicker subfoveal choroidal thickness (SFCT) (p < 0.001), greater ratio of Haller layer to SFCT (p < 0.001), and lower choroidal vascularity index (p = 0.023), compared to controls. In unaffected fellow eyes, the ratio of the Haller layer to SFCT was greater (p < 0.001) than in controls. During a 58.91-month mean follow-up, nine (16%) fellow eyes developed new PCV. These eyes showed a greater ratio of Haller layer to SFCT at baseline (p < 0.001) compared to the other fellow eyes. We also observed a numerical change in the choroidal vascularity index during follow-up of fellow eyes that developed new PCV.

Conclusion

The dilation of the Haller layer was prominent in PCV eyes and fellow eyes, compared to normal controls. In the fellow eyes that developed new PCV lesions, there were changes in the choroidal vascularity during follow-up.

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Titel: Analysis of choroidal thickness and vascularity in patients with unilateral polypoidal choroidal vasculopathy
verfasst von: Kook Lee
Jin-Heung Park
Young Gun Park
Young-Hoon Park
Publikationsdatum: 10.02.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 6/2020
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-020-04620-z

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Analysis of choroidal thickness and vascularity in patients with unilateral polypoidal choroidal vasculopathy

Abstract

Purpose

Methods

Results

Conclusion

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

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Conclusion

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