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Annals of Intensive Care

Ausgabe 1/2018

Inhalt (127 Artikel)

Open Access Research

Oleic acid chlorohydrin, a new early biomarker for the prediction of acute pancreatitis severity in humans

Enrique de-Madaria, Xavier Molero, Laia Bonjoch, Josefina Casas, Karina Cárdenas-Jaén, Andrea Montenegro, Daniel Closa

Open Access Research

Cardiac function during weaning failure: the role of diastolic dysfunction

Ferran Roche-Campo, Alexandre Bedet, Emmanuel Vivier, Laurent Brochard, Armand Mekontso Dessap

Open Access Research

Extracorporeal membrane oxygenation for severe Middle East respiratory syndrome coronavirus

Mohammed S. Alshahrani, Anees Sindi, Fayez Alshamsi, Awad Al-Omari, Mohamed El Tahan, Bayan Alahmadi, Ahmed Zein, Naif Khatani, Fahad Al-Hameed, Sultan Alamri, Mohammed Abdelzaher, Amenah Alghamdi, Faisal Alfousan, Adel Tash, Wail Tashkandi, Rajaa Alraddadi, Kim Lewis, Mohammed Badawee, Yaseen M. Arabi, Eddy Fan, Waleed Alhazzani

Open Access Research

Nutrition delivery of a model-based ICU glycaemic control system

Kent W. Stewart, J. Geoffrey Chase, Christopher G. Pretty, Geoffrey M. Shaw

Open Access Research

Quality of inter-hospital transportation in 431 transport survivor patients suffering from acute respiratory distress syndrome referred to specialist centers

Sebastian Blecha, Frank Dodoo-Schittko, Susanne Brandstetter, Magdalena Brandl, Michael Dittmar, Bernhard M. Graf, Christian Karagiannidis, Christian Apfelbacher, Thomas Bein, Johannes Bickenbach, Thorben Beeker, Tobias Schürholz, Jessica Pezechk, Jens Schloer, Ulrich Jaschinski, Ilse Kreuzer, Oliver Kuckein, Steffen Weber-Carstens, Anton Goldmann, Stefan Angermair, Krista Stoycheva, Jörg Brederlau, Nadja Rieckehr, Gabriele Schreiber, Henriette Haennicke, Friedhelm Bach, Immo Gummelt, Silke Haas, Catharina Middeke, Ina Vedder, Marion Klaproth, Michael Adamzik, Jan Karlik, Stefan Martini, Luisa Robitzky, Christian Putensen, Thomas Muders, Ute Lohmer, Rolf Dembinski, Petra Schäffner, Petra Wulff-Werner, Elke Landsiedel-Mechenbier, Daniela Nickoleit-Bitzenberger, Ann-Kathrin Silber, Maximilian Ragaller, Marcello Gama de Abreu, Alin Ulbricht, Linda Reisbach, Kai Zacharowski, Patrick Meybohm, Karin Pense, Gerhard Schwarzmann, Johannes Reske, Alexander Hötzel, Johannes Kalbhenn, Christoph Metz, Stefan Haschka, Stefan Rauch, Michael Quintel, Lars-Olav Harnisch, Sophie Baumann, Andrea Kernchen, Sigrun Friesecke, Sebastian Maletzki, Stefan Kluge, Olaf Boenisch, Daniel Frings, Birgit Füllekrug, Nils Jahn, Knut Kampe, Grit Ringeis, Brigitte Singer, Robin Wüstenberg, Jörg Ahrens, Heiner Ruschulte, Andre Gerdes, Matthias Groß, Olaf Wiesner, Aleksandra Bayat-Graw, Thorsten Brenner, Felix Schmitt, Anna Lipinski, Dietrich Henzler, Klaas Eickmeyer, Juliane Krebs, Iris Rodenberg, Heinrich Groesdonk, Kathrin Meiers, Karen Salm, Thomas Volk, Stefan Fischer, Basam Redwan, Martin Schmölz, Kathrin Schumann-Stoiber, Simone Eberl, Gunther Lenz, Thomas von Wernitz-Keibel, Monika Zackel, Frank Bloos, Petra Bloos, Anke Braune, Anja Haucke, Almut Noack, Steffi Kolanos, Heike Kuhnsch, Karina Knuhr-Kohlberg, Markus Gehling, Mathias Haller, Anne Sturm, Jannik Rossenbach, Dirk Schädler, Stefanie D’Aria, Christian Karagiannidis, Stephan Straßmann, Wolfram Windisch, Thorsten Annecke, Holger Herff, Michael Schütz, Sven Bercker, Hannah Reising, Mandy Dathe, Christian Schlegel, Katrin Lichy, Wolfgang Zink, Jana Kötteritzsch, Marc Bodenstein, Susanne Mauff, Peter Straub, Christof Strang, Florian Prätsch, Thomas Hachenberg, Thomas Kirschning, Thomas Friedrich, Dennis Mangold, Caroline Rolfes, Tilo Koch, Hendrik Haake, Katrin Offermanns, Patrick Friederich, Florian Bingold, Michael Irlbeck, Bernhard Zwissler, Ines Kaufmann, Ralph Bogdanski, Barbara Kapfer, Markus Heim, Günther Edenharter, Björn Ellger, Daniela Bause, Götz Gerresheim, Dorothea Muschner, Michael Christ, Arnim Geise, Martin Beiderlinden, Thorsten Heuter, Alexander Wipfel, Werner Kargl, Marion Harth, Christian Englmeier, Thomas Bein, Sebastian Blecha, Kathrin Thomann-Hackner, Marius Zeder, Markus Stephan, Martin Glaser, Helene Häberle, Hendrik Bracht, Christian Heer, Theresa Mast, Markus Kredel, Ralf Müllenbach

Open Access Research

Internal jugular vein variability predicts fluid responsiveness in cardiac surgical patients with mechanical ventilation

Guo-guang Ma, Guang-wei Hao, Xiao-mei Yang, Du-ming Zhu, Lan Liu, Hua Liu, Guo-wei Tu, Zhe Luo

Open Access Research

Thromboelastography-based anticoagulation management during extracorporeal membrane oxygenation: a safety and feasibility pilot study

Mauro Panigada, Giacomo E. Iapichino, Matteo Brioni, Giovanna Panarello, Alessandro Protti, Giacomo Grasselli, Giovanna Occhipinti, Cristina Novembrino, Dario Consonni, Antonio Arcadipane, Luciano Gattinoni, Antonio Pesenti

Open Access Research

Response to different furosemide doses predicts AKI progression in ICU patients with elevated plasma NGAL levels

Ryo Matsuura, Yohei Komaru, Yoshihisa Miyamoto, Teruhiko Yoshida, Kohei Yoshimoto, Rei Isshiki, Kengo Mayumi, Tetsushi Yamashita, Yoshifumi Hamasaki, Masaomi Nangaku, Eisei Noiri, Naoto Morimura, Kent Doi

Open Access Research

The host response in critically ill sepsis patients on statin therapy: a prospective observational study

Maryse A. Wiewel, Brendon P. Scicluna, Lonneke A. van Vught, Arie J. Hoogendijk, Aeilko H. Zwinderman, René Lutter, Janneke Horn, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz, Tom van der Poll

Open Access Research

Stool cultures at the ICU: get rid of it!

Carolin F. Manthey, Darja Dranova, Martin Christner, Laura Berneking, Stefan Kluge, Ansgar W. Lohse, Valentin Fuhrmann

Open Access Research

Comparison between a nurse-led weaning protocol and weaning based on physician’s clinical judgment in tracheostomized critically ill patients: a pilot randomized controlled clinical trial

Nazzareno Fagoni, Simone Piva, Elena Peli, Fabio Turla, Elisabetta Pecci, Livio Gualdoni, Bertilla Fiorese, Frank Rasulo, Nicola Latronico

Open Access Research

Transcutaneous electromyographic respiratory muscle recordings to quantify patient–ventilator interaction in mechanically ventilated children

Alette A. Koopman, Robert G. T. Blokpoel, Leo A. van Eykern, Frans H. C. de Jongh, Johannes G. M. Burgerhof, Martin C. J. Kneyber

Open Access Research

Reliability of respiratory pressure measurements in ventilated and non-ventilated patients in ICU: an observational study

Clément Medrinal, Guillaume Prieur, Yann Combret, Aurora Robledo Quesada, Tristan Bonnevie, Francis Edouard Gravier, Eric Frenoy, Olivier Contal, Bouchra Lamia

Open Access Research

Epidemiology, causes, evolution and outcome in a single-center cohort of 1116 critically ill patients with hypoxic hepatitis

Astrid Van den broecke, Laura Van Coile, Alexander Decruyenaere, Kirsten Colpaert, Dominique Benoit, Hans Van Vlierberghe, Johan Decruyenaere

Open Access Research

Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis

Djillali Annane, Jean-Paul Mira, Lorraine B. Ware, Anthony C. Gordon, Charles J. Hinds, David C. Christiani, Jonathan Sevransky, Kathleen Barnes, Timothy G. Buchman, Patrick J. Heagerty, Robert Balshaw, Nadia Lesnikova, Karen de Nobrega, Hugh F. Wellman, Mauricio Neira, Alexandra D. J. Mancini, Keith R. Walley, James A. Russell

Open Access Review

New perspectives to improve critical care benchmarking

Jorge I. F. Salluh, Jean Daniel Chiche, Carlos Eduardo Reis, Marcio Soares

Open Access Research

Physiological predictors of respiratory and cough assistance needs after extubation

Nicolas Terzi, Frédéric Lofaso, Romain Masson, Pascal Beuret, Hervé Normand, Edith Dumanowski, Line Falaize, Bertrand Sauneuf, Cédric Daubin, Jennifer Brunet, Djillali Annane, Jean-Jacques Parienti, David Orlikowski

Open Access Research

The effect of a medication reconciliation program in two intensive care units in the Netherlands: a prospective intervention study with a before and after design

Liesbeth B. E. Bosma, Nicole G. M. Hunfeld, Rogier A. M. Quax, Edmé Meuwese, Piet H. G. J. Melief, Jasper van Bommel, SiokSwan Tan, Maaike J. van Kranenburg, Patricia M. L. A. van den Bemt

Open Access Research

Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study

Joo-Yeon Engelen-Lee, Matthijs C. Brouwer, Eleonora Aronica, Diederik van de Beek

Open Access Review

Assessment of fluid responsiveness in spontaneously breathing patients: a systematic review of literature

Renato Carneiro de Freitas Chaves, Thiago Domingos Corrêa, Ary Serpa Neto, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, Fabio Tanzillo Moreira, Karina Tavares Timenetsky, Murillo Santucci Cesar de Assunção

Open Access Review

Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes

Joana Gameiro, José Agapito Fonseca, Marta Neves, Sofia Jorge, José António Lopes

Open Access Research

Plasma microRNAs levels are different between pulmonary and extrapulmonary ARDS patients: a clinical observational study

Yi Zheng, Song-qiao Liu, Qin Sun, Jian-feng Xie, Jing-yuan Xu, Qing Li, Chun Pan, Ling Liu, Ying-zi Huang

Open Access Research

Sodium lactate improves renal microvascular thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an experimental randomized open label controlled study

Thibault Duburcq, Arthur Durand, Antoine Tournoys, Viviane Gnemmi, Valery Gmyr, François Pattou, Mercedes Jourdain, Fabienne Tamion, Emmanuel Besnier, Sebastien Préau, Erika Parmentier-Decrucq, Daniel Mathieu, Julien Poissy, Raphaël Favory

Open Access Research

Lung volumes and lung volume recruitment in ARDS: a comparison between supine and prone position

Hernan Aguirre-Bermeo, Marta Turella, Maddalena Bitondo, Juan Grandjean, Stefano Italiano, Olimpia Festa, Indalecio Morán, Jordi Mancebo

Open Access Research

Acute kidney injury epidemiology, risk factors, and outcomes in critically ill patients 16–25 years of age treated in an adult intensive care unit

Dana Y. Fuhrman, Sandra Kane-Gill, Stuart L. Goldstein, Priyanka Priyanka, John A. Kellum

Open Access Research

Fluid therapy and outcome: a prospective observational study in 65 German intensive care units between 2010 and 2011

Christian Ertmer, Bernhard Zwißler, Hugo Van Aken, Michael Christ, Fabian Spöhr, Axel Schneider, Robert Deisz, Matthias Jacob

Open Access Review

Impaired aspirin-mediated platelet function inhibition in resuscitated patients with acute myocardial infarction treated with therapeutic hypothermia: a prospective, observational, non-randomized single-centre study

Florian Prüller, Oliver Leopold Milke, Lukasz Bis, Friedrich Fruhwald, Daniel Scherr, Philipp Eller, Sascha Pätzold, Siegfried Altmanninger-Sock, Peter Rainer, Jolanta Siller-Matula, Dirk von Lewinski

Open Access Research

Use of speckle-tracking strain in preload-dependent patients, need for cautious interpretation!

C. Nafati, M. Gardette, M. Leone, L. Reydellet, V. Blasco, A. Lannelongue, F. Sayagh, S. Wiramus, F. Antonini, J. Albanèse, L. Zieleskiewicz

Open Access Research

Duration of acute kidney injury in critically ill patients

Christine K. Federspiel, Theis S. Itenov, Kala Mehta, Raymond K. Hsu, Morten H. Bestle, Kathleen D. Liu

Open Access Research

The effect of multidisciplinary extracorporeal membrane oxygenation team on clinical outcomes in patients with severe acute respiratory failure

Soo Jin Na, Chi Ryang Chung, Hee Jung Choi, Yang Hyun Cho, Kiick Sung, Jeong Hoon Yang, Gee Young Suh, Kyeongman Jeon

Open Access Correction

Correction to: Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critically ill patients?

Antoine Dewitte, Sébastien Lepreux, Julien Villeneuve, Claire Rigothier, Christian Combe, Alexandre Ouattara, Jean Ripoche

Open Access Research

The 2014 updated version of the Confusion Assessment Method for the Intensive Care Unit compared to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders and other current methods used by intensivists

Gérald Chanques, E. Wesley Ely, Océane Garnier, Fanny Perrigault, Anaïs Eloi, Julie Carr, Christine M. Rowan, Albert Prades, Audrey de Jong, Sylvie Moritz-Gasser, Nicolas Molinari, Samir Jaber

Open Access Research

The prognostic value of bispectral index and suppression ratio monitoring after out-of-hospital cardiac arrest: a prospective observational study

Ward Eertmans, Cornelia Genbrugge, Margot Vander Laenen, Willem Boer, Dieter Mesotten, Jo Dens, Frank Jans, Cathy De Deyne

Open Access Research

Predictors of response to fixed-dose vasopressin in adult patients with septic shock

Gretchen L. Sacha, Simon W. Lam, Abhijit Duggal, Heather Torbic, Stephanie N. Bass, Sarah C. Welch, Robert S. Butler, Seth R. Bauer

Open Access Research

Occurrence of marked sepsis-induced immunosuppression in pediatric septic shock: a pilot study

Solenn Remy, Karine Kolev-Descamps, Morgane Gossez, Fabienne Venet, Julie Demaret, Etienne Javouhey, Guillaume Monneret

Open Access Review

Tracheotomy in the intensive care unit: guidelines from a French expert panel

Jean Louis Trouillet, Olivier Collange, Fouad Belafia, François Blot, Gilles Capellier, Eric Cesareo, Jean-Michel Constantin, Alexandre Demoule, Jean-Luc Diehl, Pierre-Grégoire Guinot, Franck Jegoux, Erwan L’Her, Charles-Edouard Luyt, Yazine Mahjoub, Julien Mayaux, Hervé Quintard, François Ravat, Sebastien Vergez, Julien Amour, Max Guillot

Open Access Research

Quality of life and life satisfaction are severely impaired in patients with long-term invasive ventilation following ICU treatment and unsuccessful weaning

Sophie Emilia Huttmann, Friederike Sophie Magnet, Christian Karagiannidis, Jan Hendrik Storre, Wolfram Windisch

Open Access Research

Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT

Fabienne D. Simonis, Carmen S. V. Barbas, Antonio Artigas-Raventós, Jaume Canet, Rogier M. Determann, James Anstey, Goran Hedenstierna, Sabrine N. T. Hemmes, Greet Hermans, Michael Hiesmayr, Markus W. Hollmann, Samir Jaber, Ignacio Martin-Loeches, Gary H. Mills, Rupert M. Pearse, Christian Putensen, Werner Schmid, Paolo Severgnini, Roger Smith, Tanja A. Treschan, Edda M. Tschernko, Marcos F. Vidal Melo, Hermann Wrigge, Marcelo Gama de Abreu, Paolo Pelosi, Marcus J. Schultz, Ary Serpa Neto, Ary Serpa Neto, Carmen S. V. Barbas, Antonio Artigas-Raventós, Jaume Canet, Rogier M. Determann, Barry Dixon, Goran Hedenstierna, Sabrine N. T. Hemmes, Greet Hermans, Michael Hiesmayr, Markus W. Hollmann, Samir Jaber, Ignacio Martin-Loeches, Gary H. Mills, Rupert M. Pearse, Christian Putensen, Werner Schmid, Paolo Severgnini, Roger Smith, Tanja A. Treschan, Edda M. Tschernko, Marcos F. Vidal Melo, Hermann Wrigge, Marcelo Gama de Abreu, Paolo Pelosi, Marcus J. Schultz, Fabienne D. Simonis

Open Access Research

In-hospital and day-120 survival of critically ill solid cancer patients after discharge of the intensive care units: results of a retrospective multicenter study—A Groupe de recherche respiratoire en réanimation en Onco–Hématologie (Grrr-OH) study

François Vincent, Marcio Soares, Djamel Mokart, Virginie Lemiale, Fabrice Bruneel, Marouane Boubaya, Frédéric Gonzalez, Yves Cohen, Elie Azoulay, Michaël Darmon

Open Access Research

Removal of totally implanted venous access ports for suspected infection in the intensive care unit: a multicenter observational study

Marie Lecronier, Sandrine Valade, Naike Bigé, Nicolas de Prost, Damien Roux, David Lebeaux, Eric Maury, Elie Azoulay, Alexandre Demoule, Martin Dres

Open Access Research

Nucleated red blood cells as predictors of mortality in patients with acute respiratory distress syndrome (ARDS): an observational study

Mario Menk, Lena Giebelhäuser, Gerald Vorderwülbecke, Martina Gassner, Jan A. Graw, Björn Weiss, Mathias Zimmermann, Klaus-D. Wernecke, Steffen Weber-Carstens

Open Access Review

Hyperchloraemia in sepsis

Christos Filis, Ioannis Vasileiadis, Antonia Koutsoukou

Open Access Research

Mortality and detailed characteristics of pre-ICU qSOFA-negative patients with suspected sepsis: an observational study

Izumi Nakayama, Junichi Izawa, Hideyuki Mouri, Tetsuhisa Kitamura, Junji Shiotsuka

Open Access Research

A novel sampling method to detect airborne influenza and other respiratory viruses in mechanically ventilated patients: a feasibility study

Alicia B. Mitchell, Benjamin Tang, Maryam Shojaei, Lachlan S. Barnes, Marek Nalos, Brian G. Oliver, Anthony S. McLean

Open Access Research

Biological scoring system for early prediction of acute bowel ischemia after cardiac surgery: the PALM score

Elie Zogheib, Cyril Cosse, Charles Sabbagh, Simon Marx, Thierry Caus, Marc Henry, Joseph Nader, Mathurin Fumery, Michael Bernasinski, Patricia Besserve, Faouzi Trojette, Cedric Renard, Pierre Duhaut, Said Kamel, Jean-Marc Regimbeau, Hervé Dupont

Open Access Review

The prognostic impact of abdominal surgery in cancer patients with neutropenic enterocolitis: a systematic review and meta-analysis, on behalf the Groupe de Recherche en Réanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)

Colombe Saillard, Lara Zafrani, Michael Darmon, Magali Bisbal, Laurent Chow-Chine, Antoine Sannini, Jean-Paul Brun, Jacques Ewald, Olivier Turrini, Marion Faucher, Elie Azoulay, Djamel Mokart

Open Access Research

Acid–base status and its clinical implications in critically ill patients with cirrhosis, acute-on-chronic liver failure and without liver disease

Andreas Drolz, Thomas Horvatits, Kevin Roedl, Karoline Rutter, Richard Brunner, Christian Zauner, Peter Schellongowski, Gottfried Heinz, Georg-Christian Funk, Michael Trauner, Bruno Schneeweiss, Valentin Fuhrmann

Open Access Research

De-escalation of antifungal treatment in critically ill patients with suspected invasive Candida infection: incidence, associated factors, and safety

Karim Jaffal, Julien Poissy, Anahita Rouze, Sébastien Preau, Boualem Sendid, Marjorie Cornu, Saad Nseir

Open Access Research

Point-of-care ultrasonography in Brazilian intensive care units: a national survey

José Augusto Santos Pellegrini, Ricardo Luiz Cordioli, Ana Cristina Burigo Grumann, Patrícia Klarmann Ziegelmann, Leandro Utino Taniguchi

Open Access Research

Early goal-directed therapy using a physiological holistic view: the ANDROMEDA-SHOCK—a randomized controlled trial

Glenn Hernández, Alexandre Biasi Cavalcanti, Gustavo Ospina-Tascón, Fernando Godinho Zampieri, Arnaldo Dubin, F. Javier Hurtado, Gilberto Friedman, Ricardo Castro, Leyla Alegría, Maurizio Cecconi, Jean-Louis Teboul, Jan Bakker, Glenn Hernandez, Gustavo Ospina-Tascón, Alexandre Cavalcanti, Arnaldo Dubin, Javier Hurtado, Gilberto Friedman, Ricardo Castro, Leyla Alegría, Jean-Louis Teboul, Maurizio Cecconi, Fernando Zampieri, Lucas Petri Damiani, Jan Bakker, Giorgio Ferri, Nicolás Rodriguez, Patricia Holger, Natalia Soto, Mario Pozo, Deborah Cook, Jean-Louis Vincent, Andrew Rhodes, Bryan Kavanagh, Phil Dellinger, Wim Rietdijk, David Carpio, Nicolás Pavéz, Elizabeth Henriquez, Sebastian Bravo, Emilio Daniel Valenzuela, Maria Alicia Cid, Ronald Pairumani, Macarena Larroulet, Edward Petruska, Claudio Sarabia, David Gallardo, Juan Eduardo Sanchez, Hugo González, José Miguel Arancibia, Alex Muñoz, Germán Ramirez, Florencia Aravena, Andrés Aquevedo, Fabián Zambrano, Milan Bozinovic, Felipe Valle, Manuel Ramirez, Victor Rossel, Pilar Muñoz, Carolina Ceballos, Christian Esveile, Cristian Carmona, Eva Candia, Daniela Mendoza, Aída Sanchez, Paula Fernández, Daniela Ponce, Jaime Lastra, Bárbara Nahuelpán, Fabrizio Fasce, Cecilia Luengo, Nicolas Medel, Cesar Cortés, Luz Campassi, Paolo Rubatto, Brenda Nahime Horna, Mariano Furche, Juan Carlos Pendino, Lisandro Bettini, Carlos Lovesio, María Cecilia González, Jésica Rodruguez, Elisa Estenssoro, Héctor Canales, Francisco Caminos, Cayetano Galletti, Estefanía Minoldo, María José Aramburu, Daniela Olmos, Nicolás Nin, Jordán Tenzi, Carlos Quiroga, Pablo Lacuesta, Agustín Gaudín, Richard Pais, Ana Silvestre, Germán Olivera, Gloria Rieppi, Dolores Berrutti, Marcelo Ochoa, Paul Cobos, Fernando Vintimilla, Vanessa Ramirez, Milton Tobar, Manuel Jibaja, Fernanda García, Fabricio Picoita, Nelson Remache, Vladimir Granda, Fernando Paredes, Eduardo Barzallo, Paul Garcés, Fausto Guerrero, Santiago Salazar, German Torres, Cristian Tana, José Calahorrano, Freddy Solis, Pedro Torres, Luís Herrera, Antonio Ornes, Verónica Peréz, Glenda Delgado, Alexei Carbonell, Eliana Espinosa, José Moreira, Diego Barahona, Blanca Salcedo, Ivonne Villacres, Jhonny Suing, Marco Lopez, Luis Gomez, Guillermo Toctaquiza, Mario Cadena Zapata, Milton Alonso Orazabal, Ruben Pardo Espejo, Jorge Jimenez, Alexander Calderón, Gustavo Paredes, José Luis Barberán, Tatiana Moya, Horacio Atehortua, Rodolfo Sabogal, Guillermo Ortiz, Antonio Lara, Fabio Sanchez, Alvaro Hernán Portilla, Humberto Dávila, Jorge Antonio Mora, Gustavo Ospina-Tascón, Luis Eduardo Calderón, Ingrid Alvarez, Elena Escobar, Alejandro Bejarano, Luis Alfonso Bustamante

Open Access Research

Diaphragm function and weaning from mechanical ventilation: an ultrasound and phrenic nerve stimulation clinical study

Martin Dres, Ewan C. Goligher, Bruno-Pierre Dubé, Elise Morawiec, Laurence Dangers, Danielle Reuter, Julien Mayaux, Thomas Similowski, Alexandre Demoule

Open Access Review

My patient has received fluid. How to assess its efficacy and side effects?

Xavier Monnet, Jean-Louis Teboul

Open Access Research

Iron metabolism in critically ill patients developing anemia of inflammation: a case control study

Margit Boshuizen, Jan M. Binnekade, Benjamin Nota, Kirsten van de Groep, Olaf L. Cremer, Pieter R. Tuinman, Janneke Horn, Marcus J. Schultz, Robin van Bruggen, Nicole P. Juffermans, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Roosmarijn T. M. van Hooijdonk, Laura R. A. Schouten, Marleen Straat, Esther Witteveen, Luuk Wieske, Arie J. Hoogendijk, Mischa A. Huson, Brendon P. Scicluna, Tom van der Poll, Lonneke A. van Vught, Maryse A. Wiewel, Marc J. M. Bonten, Jos F. Frencken, Peter M. C. Klein Klouwenberg, Maria E. Koster-Brouwer, David S. Y. Ong, Diana M. Verboom

Open Access Research

Hypothermic total liquid ventilation after experimental aspiration-associated acute respiratory distress syndrome

Jérôme Rambaud, Fanny Lidouren, Michaël Sage, Matthias Kohlhauer, Mathieu Nadeau, Étienne Fortin-Pellerin, Philippe Micheau, Luca Zilberstein, Nicolas Mongardon, Jean-Damien Ricard, Megumi Terada, Patrick Bruneval, Alain Berdeaux, Bijan Ghaleh, Hervé Walti, Renaud Tissier

Open Access Review

Data-driving methods: More than merely trendy buzzwords?

Julien Textoris, Fabio Silvio Taccone, Lara Zafrani, Antoine Guillon, Sébastien Gibot, Fabrice Uhel, Eric Azabou, Guillaume Monneret, Frédéric Pène, Nicolas de Prost, Stein Silva

Open Access Research

Midazolam increases preload dependency during endotoxic shock in rabbits by affecting venous vascular tone

Jianxiao Chen, Tao Yu, Federico Longhini, Xiwen Zhang, Songqiao Liu, Ling Liu, Yi Yang, Haibo Qiu

Open Access Research

Skin microcirculatory reactivity assessed using a thermal challenge is decreased in patients with circulatory shock and associated with outcome

Diego Orbegozo, Wasineenart Mongkolpun, Gianni Stringari, Nikolaos Markou, Jacques Creteur, Jean-Louis Vincent, Daniel De Backer

Open Access Research

Increase in intra-abdominal pressure during airway suctioning-induced cough after a successful spontaneous breathing trial is associated with extubation outcome

Yasuhiro Norisue, Jun Kataoka, Yosuke Homma, Takaki Naito, Junpei Tsukuda, Kentaro Okamoto, Takeshi Kawaguchi, Lonny Ashworth, Shimada Yumiko, Yuiko Hoshina, Eiji Hiraoka, Shigeki Fujitani

Open Access Research

Severe metabolic acidosis after out-of-hospital cardiac arrest: risk factors and association with outcome

Matthieu Jamme, Omar Ben Hadj Salem, Lucie Guillemet, Pierre Dupland, Wulfran Bougouin, Julien Charpentier, Jean-Paul Mira, Frédéric Pène, Florence Dumas, Alain Cariou, Guillaume Geri

Open Access Research

Association of intensive care unit delirium with sleep disturbance and functional disability after critical illness: an observational cohort study

Marcus T. Altman, Melissa P. Knauert, Terrence E. Murphy, Amy M. Ahasic, Zeeshan Chauhan, Margaret A. Pisani

Open Access Research

MicroDAIMON study: Microcirculatory DAIly MONitoring in critically ill patients: a prospective observational study

Claudia Scorcella, Elisa Damiani, Roberta Domizi, Silvia Pierantozzi, Stefania Tondi, Andrea Carsetti, Silvia Ciucani, Valentina Monaldi, Mara Rogani, Benedetto Marini, Erica Adrario, Rocco Romano, Can Ince, E. Christiaan Boerma, Abele Donati

Open Access Research

Impact of a VAP bundle in Belgian intensive care units

Laurent Jadot, Luc Huyghens, Annick De Jaeger, Marc Bourgeois, Dominique Biarent, Adeline Higuet, Koen de Decker, Margot Vander Laenen, Baudewijn Oosterlynck, Patrick Ferdinande, Pascal Reper, Serge Brimioulle, Sophie Van Cromphaut, Stéphane Clement De Clety, Thierry Sottiaux, Pierre Damas

Open Access Review

Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy

Manu L. N. G. Malbrain, Niels Van Regenmortel, Bernd Saugel, Brecht De Tavernier, Pieter-Jan Van Gaal, Olivier Joannes-Boyau, Jean-Louis Teboul, Todd W. Rice, Monty Mythen, Xavier Monnet

Open Access Research

Carotid and femoral Doppler do not allow the assessment of passive leg raising effects

Valentina Girotto, Jean-Louis Teboul, Alexandra Beurton, Laura Galarza, Thierry Guedj, Christian Richard, Xavier Monnet

Open Access Research

Adherence to a procalcitonin-guided antibiotic treatment protocol in patients with severe sepsis and septic shock

Andreas Hohn, Nina Balfer, Bernhard Heising, Sabine Hertel, Jan C. Wiemer, Marcel Hochreiter, Stefan Schröder

Open Access Research

Comparative effectiveness of elemental formula in the early enteral nutrition management of acute pancreatitis: a retrospective cohort study

Akira Endo, Atsushi Shiraishi, Kiyohide Fushimi, Kiyoshi Murata, Yasuhiro Otomo

Open Access Research

The safety and efficacy of nicotine replacement therapy in the intensive care unit: a randomised controlled pilot study

Ben de Jong, Anne Sophie Schuppers, Arriette Kruisdijk-Gerritsen, Maurits Erwin Leo Arbouw, Hubertus Laurentius Antonius van den Oever, Arthur R. H. van Zanten

Open Access Review

Effectiveness of antimicrobial-coated central venous catheters for preventing catheter-related blood-stream infections with the implementation of bundles: a systematic review and network meta-analysis

Hongliang Wang, Hongshuang Tong, Haitao Liu, Yao Wang, Ruitao Wang, Hong Gao, Pulin Yu, Yanji Lv, Shuangshuang Chen, Guiyue Wang, Miao Liu, Yuhang Li, Kaijiang Yu, Changsong Wang

Open Access Research

Vascular complications in adult postcardiotomy cardiogenic shock patients receiving venoarterial extracorporeal membrane oxygenation

Feng Yang, Dengbang Hou, Jinhong Wang, Yongchao Cui, Xiaomeng Wang, Zhichen Xing, Chunjing Jiang, Xing Hao, Zhongtao Du, Xiaofang Yang, Yu Jiang, Xiaotong Hou

Open Access Review

Estimating mean circulatory filling pressure in clinical practice: a systematic review comparing three bedside methods in the critically ill

Marije Wijnberge, Daniko P. Sindhunata, Michael R. Pinsky, Alexander P. Vlaar, Else Ouweneel, Jos R. Jansen, Denise P. Veelo, Bart F. Geerts

Open Access Research

Clinical impact of upper gastrointestinal endoscopy in critically ill patients with suspected bleeding

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S. Figueiredo, C. Taconet, A. Harrois, S. Hamada, T. Gauss, M. Raux, J. Duranteau, Arie Attias, Sylvain Ausset, Mathieu Boutonnet, Gilles Dhonneur, Olivier Langeron, Catherine Paugam-Burtz, Romain Pirracchio, Bruno Riou, Guillaume de St Maurice, Bernard Vigué

Open Access Research

Prediction of chronic kidney disease after acute kidney injury in ICU patients: study protocol for the PREDICT multicenter prospective observational study

Guillaume Geri, Bénédicte Stengel, Christian Jacquelinet, Philippe Aegerter, Ziad A. Massy, Antoine Vieillard-Baron, Stéphane Legriel, Virginie Laurent, Jean-Louis Teboul, Anatole Virginie Tarazona, Armand Mekontso-Dessap, Jean-Paul Mira, Jean-Luc Diehl, Romain Pirracchio, Naike Bigé, Claire Dupuis, Stéphane Gaudry, Julien Maizel, Bertrand Souweine, Lara Zafrani, Bruno Mégarbane, Alexandre Mebazaa, Antoine Durbach, Vincent Audard, Eric Thervet, Jean-Jacques Boffa, Guillaume Hanouna, Dimitri Titeca, Carole Philiponnet, Denis Glotz

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Large-volume paracentesis effects plasma disappearance rate of indo-cyanine green in critically ill patients with decompensated liver cirrhosis and intraabdominal hypertension

Ulrich Mayr, Leonie Fahrenkrog-Petersen, Gonzalo Batres-Baires, Alexander Herner, Sebastian Rasch, Roland M. Schmid, Wolfgang Huber, Tobias Lahmer

Open Access Research

Respiratory changes of the inferior vena cava diameter predict fluid responsiveness in spontaneously breathing patients with cardiac arrhythmias

Perrine Bortolotti, Delphine Colling, Vincent Colas, Benoit Voisin, Florent Dewavrin, Julien Poissy, Patrick Girardie, Maeva Kyheng, Fabienne Saulnier, Raphael Favory, Sebastien Preau

Open Access Research

Characteristics and outcome of patients with newly diagnosed advanced or metastatic lung cancer admitted to intensive care units (ICUs)

C. Barth, M. Soares, A. C. Toffart, J. F. Timsit, G. Burghi, C. Irrazabal, N. Pattison, E. Tobar, B. F. Almeida, U. V. Silva, L. C. Azevedo, A. Rabbat, C. Lamer, A. Parrot, V. C. Souza-Dantas, F. Wallet, F. Blot, G. Bourdin, C. Piras, J. Delemazure, M. Durand, J. Salluh, E. Azoulay, Virginie Lemiale, Célica Irrazábal, Pierina Bachetti, Vicente C. Souza-Dantas, Mauro M. Zamboni, Aureliano Sousa, Bruno F. C. Almeida, Lúcio S. Santos, Pedro Caruso, Ulysses V. A. Silva, Luciano C. P. Azevedo, Guilherme P. P. Schettino, Cláudio Piras, Stéphanie B. Piras, Albano S. M. T. Silva, Eduado Tobar, Nivia Estuardo, François Blot, Bruno Raynard, Antoine Parrot, Florent Wallet, Christian Lamer, Alexandre Duguet, Alexandre Demoule, Julie Delemazure, Julien Mayaux, Thomas Similowski, Michel Durand, Geraldine Dessertaine, Pr Jean François Payen, Anne-Claire Toffart, Jean-François Timsit, Gael Bourdin, Claude Guerin, Antoine Rabbat, Aurélie Lefebvre, Élie Azoulay, Natalie Pattison, Natalie Pattison, Gastón Burghi, Gastón Burghi, Gastón Burghi

Open Access Research

Severe atypical pneumonia in critically ill patients: a retrospective multicenter study

S. Valade, L. Biard, V. Lemiale, L. Argaud, F. Pène, L. Papazian, F. Bruneel, A. Seguin, A. Kouatchet, J. Oziel, S. Rouleau, N. Bele, K. Razazi, O. Lesieur, F. Boissier, B. Megarbane, N. Bigé, N. Brulé, A. S. Moreau, A. Lautrette, O. Peyrony, P. Perez, J. Mayaux, E. Azoulay

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D. Grimaldi, S. Hraiech, E. Boutin, J. C. Lacherade, F. Boissier, T. Pham, J. C. Richard, A. W. Thille, S. Ehrmann, J. B. Lascarrou, N. Aissaoui

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Video laryngoscopy versus direct laryngoscopy for first-attempt tracheal intubation in the general ward

Moon Seong Baek, MyongJa Han, Jin Won Huh, Chae-Man Lim, Younsuck Koh, Sang-Bum Hong

Open Access Research

Ten-year trends in intensive care admissions for respiratory infections in the elderly

Lucile Laporte, Coralie Hermetet, Youenn Jouan, Christophe Gaborit, Emmanuelle Rouve, Kimberly M. Shea, Mustapha Si-Tahar, Pierre-François Dequin, Leslie Grammatico-Guillon, Antoine Guillon

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High-flow nasal oxygen versus noninvasive ventilation in adult patients with cystic fibrosis: a randomized crossover physiological study

Michael C. Sklar, Martin Dres, Nuttapol Rittayamai, Brent West, Domenico Luca Grieco, Irene Telias, Detajin Junhasavasdikul, Michela Rauseo, Tai Pham, Fabiana Madotto, Carolyn Campbell, Elizabeth Tullis, Laurent Brochard

Open Access Research

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Mehdi Mezidi, Francisco José Parrilla, Hodane Yonis, Zakaria Riad, Stephan H. Böhm, Andreas D. Waldmann, Jean-Christophe Richard, Floriane Lissonde, Romain Tapponnier, Loredana Baboi, Jordi Mancebo, Claude Guérin

Open Access Research

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Constance Vuillard, Marc Pineton de Chambrun, Nicolas de Prost, Claude Guérin, Matthieu Schmidt, Auguste Dargent, Jean-Pierre Quenot, Sébastien Préau, Geoffrey Ledoux, Mathilde Neuville, Guillaume Voiriot, Muriel Fartoukh, Rémi Coudroy, Guillaume Dumas, Eric Maury, Nicolas Terzi, Yacine Tandjaoui-Lambiotte, Francis Schneider, Maximilien Grall, Emmanuel Guérot, Romaric Larcher, Sylvie Ricome, Raphaël Le Mao, Gwenhaël Colin, Christophe Guitton, Lara Zafrani, Elise Morawiec, Marie Dubert, Olivier Pajot, Hervé Mentec, Gaëtan Plantefève, Damien Contou

Open Access Review

Streptococcal toxic shock syndrome in the intensive care unit

Marylin Schmitz, Xavier Roux, Benedikt Huttner, Jérôme Pugin

Open Access Research

Performance of closed-loop resuscitation of haemorrhagic shock with fluid alone or in combination with norepinephrine: an experimental study

Nicolas Libert, Guillaume Chenegros, Anatole Harrois, Nathalie Baudry, Gilles Cordurie, Ryad Benosman, Eric Vicaut, Jacques Duranteau

Open Access Research

Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial

Julien Demiselle, Martin Wepler, Clair Hartmann, Peter Radermacher, Frédérique Schortgen, Ferhat Meziani, Mervyn Singer, Valérie Seegers, Pierre Asfar

Open Access Review

Renal failure in critically ill patients, beware of applying (central venous) pressure on the kidney

Xiukai Chen, Xiaoting Wang, Patrick M. Honore, Herbert D. Spapen, Dawei Liu

Open Access Research

Dexmedetomidine in prevention and treatment of postoperative and intensive care unit delirium: a systematic review and meta-analysis

Julian Flükiger, Alexa Hollinger, Benjamin Speich, Vera Meier, Janna Tontsch, Tatjana Zehnder, Martin Siegemund

Open Access Research

Impact of oversedation prevention in ventilated critically ill patients: a randomized trial—the AWARE study

Bernard de Jonghe, Jérôme Aboab, Nadia Aissaoui, Djillali Annane, Corinne Audoin, Jean-Luc Baudel, Florence Brouard, Alexandre Cambonie, Isabelle Camilatto, Karim Chergui, Vincent Das, Daniel da Silva, Nicolas Devos, Nicolas Deye, Stephan Ehrmann, Frédérique Ganster, Bruno Giraudeau, David Grimaldi, Emmanuelle Gourdin, Antoine Gros, Olfa Hamzaoui, Frédéric Jacobs, Antoine Kimmoun, Jean-Claude Lacherade, Bernard Lambermont, Pierre-François Laterre, Julie Leger, Stéphane Legriel, Lucas Liaudet, Charles-Edouard Luyt, Philippe Michel, Jean-Paul Mira, Xavier Monnet, Grégoire Muller, Michael Piagnerelli, Gaëtan Plantefeve, Jean Reignier, Jean-Damien Ricard, François Vincent, Jugurtha Aliane, Fabienne Plouvier, Alain Mercat, Mohebbi Amoli Abolfazl, Gaëtan Plantefeve, Cédric Cleophax, Karim Chergui, Guillaume Carteaux, Jérôme Aboab, Jean Reignier, Gilles Troche, Laurent Guerin, Patrick Girardie, Emmanuel Vivier, Romain Hernu, Philippe Obbee, Laurence Donetti, Thierry Jacques, Aurélie Cravoisy-Popovic, Thierry Boulain, Qin Lu, Danielle Reuter, Elie Azoulay, Hervé Clavier, Walter Picard, René Robert, Renaud Chouquer, Christophe Girault, Daniel da Silva, Stéphane Merat, Charlotte Quentin, Jean-François Hicter, Maleka Schenck, Sandie Dauriac, Jean-Luc Desmaretz, Hervé Hyvernat, Alexis Soumer, Annabelle Stoclin, Jean-Philippe Rigaud, Alexandre Duguet, Laetitia Bodet-Contentin, Siu-Ming Au, Sébastien Ena

Open Access Research

Predictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning

Kuo-Chin Kao, Ko-Wei Chang, Ming-Cheng Chan, Shinn-Jye Liang, Ying-Chun Chien, Han-Chung Hu, Li-Chung Chiu, Wei-Chih Chen, Wen-Feng Fang, Yu-Mu Chen, Chau-Chyun Sheu, Ming-Ju Tsai, Wann-Cherng Perng, Chung-Kan Peng, Chieh-Liang Wu, Hao-Chien Wang, Kuang-Yao Yang

Open Access Review

Perioperative statin therapy in cardiac and non-cardiac surgery: a systematic review and meta-analysis of randomized controlled trials

Alessandro Putzu, Carolina Maria Pinto Domingues de Carvalho e Silva, Juliano Pinheiro de Almeida, Alessandro Belletti, Tiziano Cassina, Giovanni Landoni, Ludhmila Abrahao Hajjar

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Estimation of sodium and chloride storage in critically ill patients: a balance study

Lara Hessels, Annemieke Oude Lansink-Hartgring, Miriam Zeillemaker-Hoekstra, Maarten W. Nijsten

Open Access Review

Albumin infusion in spontaneous bacterial peritonitis: another brick off the wall?

Damien Roux, Richard Moreau, Didier Dreyfuss

Open Access Research

Fluoroscopy-guided simultaneous distal perfusion as a preventive strategy of limb ischemia in patients undergoing extracorporeal membrane oxygenation

Woo Jin Jang, Yang Hyun Cho, Taek Kyu Park, Young Bin Song, Jin-Oh Choi, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Eun-Seok Jeon, Woo Jung Chun, Ju Hyeon Oh, Jeong Hoon Yang

Open Access Review

Hemodynamic support in the early phase of septic shock: a review of challenges and unanswered questions

Olivier Lesur, Eugénie Delile, Pierre Asfar, Peter Radermacher

Open Access Research

Pleural effusion during weaning from mechanical ventilation: a prospective observational multicenter study

Keyvan Razazi, Florence Boissier, Mathilde Neuville, Sébastien Jochmans, Martial Tchir, Faten May, Nicolas de Prost, Christian Brun-Buisson, Guillaume Carteaux, Armand Mekontso Dessap

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Brief summary of French guidelines for the prevention, diagnosis and treatment of hospital-acquired pneumonia in ICU

Marc Leone, Lila Bouadma, Bélaïd Bouhemad, Olivier Brissaud, Stéphane Dauger, Sébastien Gibot, Sami Hraiech, Boris Jung, Eric Kipnis, Yoann Launey, Charles-Edouard Luyt, Dimitri Margetis, Fabrice Michel, Djamel Mokart, Philippe Montravers, Antoine Monsel, Saad Nseir, Jérôme Pugin, Antoine Roquilly, Lionel Velly, Jean-Ralph Zahar, Rémi Bruyère, Gérald Chanques, Fabrice Michel, Stephane Dauger, Olivier Brissaud

Open Access Research

A multinational survey on the infrastructural quality of paediatric intensive care units

Gert Warncke, Florian Hoffmann, Michael Sasse, Georg Singer, Istvan Szilagyi, Holger Till, Christoph Castellani

Open Access Research

Mean arterial pressure and mortality in patients with distributive shock: a retrospective analysis of the MIMIC-III database

Jean-Louis Vincent, Nathan D. Nielsen, Nathan I. Shapiro, Margaret E. Gerbasi, Aaron Grossman, Robin Doroff, Feng Zeng, Paul J. Young, James A. Russell

Open Access Research

ICU physicians’ and internists’ survival predictions for patients evaluated for admission to the intensive care unit

Monica Escher, Bara Ricou, Mathieu Nendaz, Fabienne Scherer, Stéphane Cullati, Patricia Hudelson, Thomas Perneger

Open Access Review

Artificial liver support systems: what is new over the last decade?

Juan José García Martínez, Karim Bendjelid

Open Access Research

Inflammatory and coagulatory parameters linked to survival in critically ill children with sepsis

Christian Niederwanger, Mirjam Bachler, Tobias Hell, Caroline Linhart, Andreas Entenmann, Agnes Balog, Katharina Auer, Petra Innerhofer

Open Access Research

Development and performance of a novel vasopressor-driven mortality prediction model in septic shock

Saraschandra Vallabhajosyula, Jacob C. Jentzer, Aditya A. Kotecha, Dennis H. Murphree Jr., Erin F. Barreto, Ashish K. Khanna, Vivek N. Iyer

Open Access Research

Sustained low efficiency dialysis should not be interrupted for performing transpulmonary thermodilution measurements

Stefanie Geith, Lynne Stecher, Christian Rabe, Stefan Sack, Florian Eyer

Open Access Review

Caring for the critically ill patients over 80: a narrative review

Bertrand Guidet, Helene Vallet, Jacques Boddaert, Dylan W. de Lange, Alessandro Morandi, Guillaume Leblanc, Antonio Artigas, Hans Flaatten

Open Access Research

Validation of a new WIND classification compared to ICC classification for weaning outcome

Byeong-Ho Jeong, Kyeong Yoon Lee, Jimyoung Nam, Myeong Gyun Ko, Soo Jin Na, Gee Young Suh, Kyeongman Jeon

Open Access Research

Evaluation of emotional excitation during standardized endotracheal intubation in simulated conditions

Nicolas S. Marjanovic, Christelle Teiten, Nicola Pallamin, Erwan L’Her

Open Access Research

Melatonin and cortisol exhibit different circadian rhythm profiles during septic shock depending on timing of onset: a prospective observational study

Eleni N. Sertaridou, Ioanna G. Chouvarda, Konstantinos I. Arvanitidis, Eirini K. Filidou, George C. Kolios, Ioannis N. Pnevmatikos, Vasilios E. Papaioannou

Open Access Research

Driving pressure and long-term outcomes in moderate/severe acute respiratory distress syndrome

Carlos Toufen Junior, Roberta R. De Santis Santiago, Adriana S. Hirota, Alysson Roncally S. Carvalho, Susimeire Gomes, Marcelo Brito Passos Amato, Carlos Roberto Ribeiro Carvalho

Open Access Research

Hemodynamic effects of extended prone position sessions in ARDS

Martin Ruste, Laurent Bitker, Hodane Yonis, Zakaria Riad, Aurore Louf-Durier, Floriane Lissonde, Sophie Perinel-Ragey, Claude Guerin, Jean-Christophe Richard

Open Access Research

Impact of hemoperfusion with polymyxin B added to hemofiltration in patients with endotoxic shock: a case–control study

Ana Navas, Ricard Ferrer, Maria Luisa Martínez, Gemma Gomà, Gisela Gili, Jordi Masip, David Suárez, Antonio Artigas

Open Access Research

Effects of the timing of administration of IgM- and IgA-enriched intravenous polyclonal immunoglobulins on the outcome of septic shock patients

Giorgio Berlot, Michele Claudio Vassallo, Nicola Busetto, Margarita Nieto Yabar, Tatiana Istrati, Silvia Baronio, Giada Quarantotto, Mattia Bixio, Giulia Barbati, Roberto Dattola, Irene Longo, Antonino Chillemi, Alice Scamperle, Fulvio Iscra, Ariella Tomasini

Open Access Research

Proportional modes versus pressure support ventilation: a systematic review and meta-analysis

Jun Kataoka, Akira Kuriyama, Yasuhiro Norisue, Shigeki Fujitani

Open Access Research

Impact of individualized target mean arterial pressure for septic shock resuscitation on the incidence of acute kidney injury: a retrospective cohort study

Rajat N. Moman, Stuart A. Ostby, Abbasali Akhoundi, Rahul Kashyap, Kianoush Kashani

Open Access Letter to the Editor

Lung ultrasound estimation of pleural effusion fluid and the importance of patient position

Luigi Vetrugno, Tiziana Bove

Open Access Research

Effect on comfort of administering bubble-humidified or dry oxygen: the Oxyrea non-inferiority randomized study

Laurent Poiroux, Lise Piquilloud, Valérie Seegers, Cyril Le Roy, Karine Colonval, Carole Agasse, Vanessa Zinzoni, Vanessa Hodebert, Alexandre Cambonie, Josselin Saletes, Irma Bourgeon, François Beloncle, Alain Mercat

Open Access Research

ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients

A. S. Truche, S. Perinel Ragey, B. Souweine, S. Bailly, L. Zafrani, L. Bouadma, C. Clec’h, M. Garrouste-Orgeas, G. Lacave, C. Schwebel, F. Guebre-Egziabher, C. Adrie, A. S. Dumenil, Ph. Zaoui, L. Argaud, S. Jamali, D. Goldran Toledano, G. Marcotte, J. F. Timsit, M. Darmon

Open Access Research

Nasal high-flow bronchodilator nebulization: a randomized cross-over study

François Reminiac, Laurent Vecellio, Laetitia Bodet-Contentin, Valérie Gissot, Deborah Le Pennec, Charlotte Salmon Gandonnière, Maria Cabrera, Pierre-François Dequin, Laurent Plantier, Stephan Ehrmann

Open Access Research

Ischemic and hemorrhagic brain injury during venoarterial-extracorporeal membrane oxygenation

Loïc Le Guennec, Clémentine Cholet, Florent Huang, Matthieu Schmidt, Nicolas Bréchot, Guillaume Hékimian, Sébastien Besset, Guillaume Lebreton, Ania Nieszkowska, Pascal Leprince, Alain Combes, Charles-Edouard Luyt

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