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Annals of Surgical Oncology

Ausgabe Sonderheft 3/2012

Inhalt (42 Artikel)

Translational Research and Biomarkers

Single Nucleotide Polymorphisms and Haplotypes of MMP-14 are Associated with the Risk and Pathological Development of Oral Cancer

Chia-Jui Weng, Mu-Kuan Chen, Chiao-Wen Lin, Tsung-Te Chung, Shun-Fa Yang

Translational Research and Biomarkers

Integrated Analysis of Prognostic Gene Expression Profiles from Hepatitis B Virus-Positive Hepatocellular Carcinoma and Adjacent Liver Tissue

Bu-Yeo Kim, Kyung-Suk Suh, Je-Geun Lee, Seon Rang Woo, In-Chul Park, Sun-Hoo Park, Chul Ju Han, Sang-Bum Kim, Sook-Hyang Jeong, Young Il Yeom, Suk-Jin Yang, Chang-Min Kim, Su Jin Cho, Young Do Yoo, Myung-Haing Cho, Ja June Jang, Dong Wook Choi, Kee-Ho Lee

Translational Research and Biomarkers

CXCR4 Expression Predicts Patient Outcome and Recurrence Patterns after Hepatic Resection for Colorectal Liver Metastases

Adam C. Yopp, Jinru Shia, Jean M. Butte, Peter J. Allen, Yuman Fong, William R. Jarnagin, Ronald P. DeMatteo, Michael I. D’Angelica

Translational Research and Biomarkers

Impact of KRAS and EGFR Gene Mutations on Recurrence and Survival in Patients with Surgically Resected Lung Adenocarcinomas

Makoto Sonobe, Masashi Kobayashi, Masashi Ishikawa, Ryutaro Kikuchi, Ei Nakayama, Tsuyoshi Takahashi, Toshi Menju, Kazumasa Takenaka, Ryo Miyahara, Cheng-Long Huang, Kenichi Okubo, Toru Bando, Hiroshi Date

Translational Research and Biomarkers

Role of the Hypoxia-Related Gene, JMJD1A, in Hepatocellular Carcinoma: Clinical Impact on Recurrence after Hepatic Resection

Daisaku Yamada, Shogo Kobayashi, Hirofumi Yamamoto, Yoshito Tomimaru, Takehiro Noda, Mamoru Uemura, Hiroshi Wada, Shigeru Marubashi, Hidetoshi Eguchi, Masahiro Tanemura, Yuichiro Doki, Masaki Mori, Hiroaki Nagano

Translational Research and Biomarkers

Different Expression Patterns of CEACAM1 and its Impacts on Angiogenesis in Gastric Nonneoplastic and Neoplastic Lesions

Jian-Qiang Guo, Wei-Hua Yu, Hong-Juan Wang, Bin Liu, Kong-Xi Zhu, Qing-Hui Zhang, Ting-Guo Zhang, Wei-Hua Xu, Hong-Bo Wang, Hong-Li Wu, Cheng-Jun Zhou

Translational Research and Biomarkers

The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection

Rongxin Chen, Jiefeng Cui, Changde Xu, Tongchun Xue, Kun Guo, Dongmei Gao, Yinkun Liu, Shenglong Ye, Zhenggang Ren

Translational Research and Biomarkers

Prognostic Significance of TWEAK Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion

Been-Ren Lin, Miao-Tzu Huang, Szu-Ta Chen, Yung-Ming Jeng, Yue-Ju Li, Jin-Tung Liang, Po-Huang Lee, King-Jen Chang, Cheng-Chi Chang

Translational Research and Biomarkers

Molecular Profiling of Direct Xenograft Tumors Established from Human Pancreatic Adenocarcinoma After Neoadjuvant Therapy

Michael P. Kim, Mark J. Truty, Woonyoung Choi, Ya’an Kang, Xavier Chopin-Lally, Gary E. Gallick, Huamin Wang, David J. McConkey, Rosa Hwang, Craig Logsdon, James Abbruzzesse, Jason B. Fleming

Translational Research and Biomarkers

Overexpression of Renal Tumor Antigen Is Associated with Tumor Invasion and Poor Prognosis of Hepatocellular Carcinoma

Hyung Jin Cha, Jongmin Kim, Sun Mi Hong, Seok Joo Hong, Jun Ho Park, Eung-Sam Kim, Hee-Jung Wang, Yoon Jung Choi, In-Gu Do, Jae Won Joh, Dae Shick Kim, Kwan Yong Choi

Translational Research and Biomarkers

Expression of IGF1R Is Associated with Tumor Differentiation and Survival in Patients with Lung Adenocarcinoma

Ryutaro Kikuchi, Makoto Sonobe, Masashi Kobayashi, Masashi Ishikawa, Jiro Kitamura, Ei Nakayama, Toshi Menju, Ryo Miyahara, Cheng-long Huang, Hiroshi Date

Translational Research and Biomarkers

Inhibition of Heat Shock Protein Response Enhances PS-341-Mediated Glioma Cell Death

Yaohua Liu, Tianhu Zheng, Shiguang Zhao, Huailei Liu, Dayong Han, Yunbo Zhen, Dongxiao Xu, Yu Wang, Hongyu Yang, Guang Zhang, Chunlei Wang, Jianing Wu, Yuanzhu Ye

Translational Research and Biomarkers

Clinical Significance of Molecular Detection of Matrix metalloproteinase-1 in Bone Marrow and Peripheral Blood in Patients with Gastric Cancer

Yoshimasa Kosaka, Koshi Mimori, Takeo Fukagawa, Kenji Ishikawa, Tsuyoshi Etoh, Hitoshi Katai, Takeshi Sano, Masahiko Watanabe, Mitsuru Sasako, Masaki Mori

Translational Research and Biomarkers

Clinicopathological Analysis of β-catenin and Axin-1 in Solid Pseudopapillary Neoplasms of the Pancreas

Shih-Chiang Huang, Kwai-Fong Ng, Ta-Sen Yeh, Hao-Cheng Chang, Chia-Yi Su, Tse-Ching Chen

Open Access Translational Research and Biomarkers

High-Intensity Focused Ultrasound (HIFU)-Assisted Hepatic Resection in an Animal Model

Alessandro Gandini, David Melodelima, Francesco Schenone, Apoutou William N’Djin, Jean Yves Chapelon, Michel Rivoire

Translational Research and Biomarkers

Recurrence and Poor Prognosis Following Resection of Small Hepatitis B-Related Hepatocellular Carcinoma Lesions Are Associated with Aberrant Tumor Expression Profiles of Glypican 3 and Osteopontin

Ming-Chin Yu, Yun-Shien Lee, Sey-En Lin, Hsiang-Yao Wu, Tse-Ching Chen, Wei-Chen Lee, Miin-Fu Chen, Chi-Neu Tsai

Translational Research and Biomarkers

High Expression of Delta-Like Ligand 4 Predicts Poor Prognosis After Curative Resection for Pancreatic Cancer

Hai-Tao Chen, Quan-Cai Cai, Jian-Ming Zheng, Xiao-Hua Man, Hui Jiang, Bin Song, Gang Jin, Wei Zhu, Zhao-Shen Li

Open Access Translational Research and Biomarkers

Intraoperative versus Early Postoperative Intraperitoneal Chemotherapy after Cytoreduction for Colorectal Peritoneal Carcinomatosis: an Experimental Study

Yvonne L. B. Klaver, Thijs Hendriks, Roger M. L. M. Lomme, Harm J. T. Rutten, Robert P. Bleichrodt, Ignace H. J. T. de Hingh

Translational Research and Biomarkers

Novel C-Terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents

Stephanie M. Cohen, Ridhwi Mukerji, Abbas K. Samadi, Huiping Zhao, Brian S. J. Blagg, Mark S. Cohen

Translational Research and Biomarkers

Claudin-4 Expression Predicts Survival in Pancreatic Ductal Adenocarcinoma

Kosuke Tsutsumi, Norihiro Sato, Reiko Tanabe, Kazuhiro Mizumoto, Katsuya Morimatsu, Tadashi Kayashima, Hayato Fujita, Kenoki Ohuchida, Takao Ohtsuka, Shunichi Takahata, Masafumi Nakamura, Masao Tanaka

Translational Research and Biomarkers

Axl Is a Prognostic Marker in Oral Squamous Cell Carcinoma

Chien-Hsing Lee, Ching-Yu Yen, Shyun-Yeu Liu, Chi-Kang Chen, Chi-Fu Chiang, Shine-Gwo Shiah, Pei-Hsuan Chen, Yi-Shing Shieh

Translational Research and Biomarkers

Inverse Association between miR-194 Expression and Tumor Invasion in Gastric Cancer

Yongxi Song, Feng Zhao, Zhenning Wang, Zhuangkai Liu, Yeunpo Chiang, Yingying Xu, Peng Gao, Huimian Xu

Translational Research and Biomarkers

Soluble CXCL16 in Preoperative Serum is a Novel Prognostic Marker and Predicts Recurrence of Liver Metastases in Colorectal Cancer Patients

Kohei Matsushita, Yuji Toiyama, Koji Tanaka, Susumu Saigusa, Junichiro Hiro, Keiichi Uchida, Yasuhiro Inoue, Masato Kusunoki

Translational Research and Biomarkers

Association of FANCC and PTCH1 with the Development of Early Dysplastic Lesions of the Head and Neck

Amlan Ghosh, Susmita Ghosh, Guru Prasad Maiti, Sudeshna Mukherjee, Nupur Mukherjee, Jayanta Chakraborty, Anup Roy, Susanta Roychoudhury, C. K. Panda

Translational Research and Biomarkers

Increased CD13 Expression Reduces Reactive Oxygen Species, Promoting Survival of Liver Cancer Stem Cells via an Epithelial–Mesenchymal Transition-like Phenomenon

Ho Min Kim, Naotsugu Haraguchi, Hideshi Ishii, Masahisa Ohkuma, Miho Okano, Koshi Mimori, Hidetoshi Eguchi, Hirofumi Yamamoto, Hiroaki Nagano, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori

Translational Research and Biomarkers

Prognostic Significance of NBS1 and Snail Expression in Esophageal Squamous Cell Carcinoma

Kuang-Tai Kuo, Teh-Ying Chou, Han-Shui Hsu, Wen-Liang Chen, Liang-Shun Wang

Translational Research and Biomarkers

Immunohistochemical Analysis of Human Equilibrative Nucleoside Transporter-1 (hENT1) Predicts Survival in Resected Pancreatic Cancer Patients Treated with Adjuvant Gemcitabine Monotherapy

Soichiro Morinaga, Yoshiyasu Nakamura, Takuo Watanabe, Hiroshi Mikayama, Hiroshi Tamagawa, Naoto Yamamoto, Manabu Shiozawa, Makoto Akaike, Shinnichi Ohkawa, Yoichi Kameda, Yohei Miyagi

Translational Research and Biomarkers

Carcinogenesis of Intraductal Papillary Mucinous Neoplasm of the Pancreas: Loss of MicroRNA-101 Promotes Overexpression of Histone Methyltransferase EZH2

Osamu Nakahara, Hiroshi Takamori, Masaaki Iwatsuki, Yoshifumi Baba, Yasuo Sakamoto, Hiroshi Tanaka, Akira Chikamoto, Kei Horino, Toru Beppu, Keiichiro Kanemitsu, Yumi Honda, Ken-ichi Iyama, Hideo Baba

Translational Research and Biomarkers

Silencing of Glucose-Regulated Protein 78 (GRP78) Enhances Cell Migration Through the Upregulation of Vimentin in Hepatocellular Carcinoma Cells

Po-Li Wei, Li-Jen Kuo, Weu Wang, Feng-Yen Lin, Hui-Hsiung Liu, Tseng How, Yuan-Soon Ho, Ming-Te Huang, Chih-Hsiung Wu, Yu-Jia Chang

Translational Research and Biomarkers

NNK Enhances Cell Migration through α7-nicotinic Acetylcholine Receptor Accompanied by Increased of Fibronectin Expression in Gastric Cancer

Weu Wang, Hung Chin-Sheng, Li-Jen Kuo, Po-Li Wei, Yung-Chang Lien, Feng-Yen Lin, Hui-Hsiung Liu, Yuan-Soon Ho, Chih-Hsiung Wu, Yu-Jia Chang

Translational Research and Biomarkers

TNFAIP8 Overexpression: Clinical Relevance to Esophageal Squamous Cell Carcinoma

Yuni Elsa Hadisaputri, Tatsuya Miyazaki, Shigemasa Suzuki, Takehiko Yokobori, Tsutomu Kobayashi, Naritaka Tanaka, Takanori Inose, Makoto Sohda, Hiroyuki Kuwano

Open Access Translational Research and Biomarkers

Tumor-Associated Antigen Expressing Listeria monocytogenes Induces Effective Primary and Memory T-Cell Responses Against Hepatic Colorectal Cancer Metastases

Kelly Olino, Satoshi Wada, Barish H. Edil, Xiaoyu Pan, Kristen Meckel, Walter Weber, Jill Slansky, Koji Tamada, Peter Lauer, Dirk Brockstedt, Drew Pardoll, Richard Schulick, Kiyoshi Yoshimura

Translational Research and Biomarkers

Cortical and Subventricular Zone Glioblastoma-Derived Stem-Like Cells Display Different Molecular Profiles and Differential In Vitro and In Vivo Properties

Aurélie Tchoghandjian, Nathalie Baeza-Kallee, Christophe Beclin, Philippe Metellus, Carole Colin, François Ducray, José Adélaïde, Geneviève Rougon, Dominique Figarella-Branger

Translational Research and Biomarkers

A Pathway-Based Approach to Identify Molecular Biomarkers in Cancer

Marvaretta Stevenson, Anil Potti

Translational Research and Biomarkers

Survivin T9809C, an SNP Located in 3′-UTR, Displays a Correlation with the Risk and Clinicopathological Development of Hepatocellular Carcinoma

Yih-Shou Hsieh, Chiung-Man Tsai, Chao-Bin Yeh, Shun-Fa Yang, Yi-Hsien Hsieh, Chia-Jui Weng

Translational Research and Biomarkers

Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells

Mihoko Horio, Mitsuo Sato, Yoshihiro Takeyama, Momen Elshazley, Ryo Yamashita, Tetsunari Hase, Kenya Yoshida, Noriyasu Usami, Kohei Yokoi, Yoshitaka Sekido, Masashi Kondo, Shinya Toyokuni, Adi F. Gazdar, John D. Minna, Yoshinori Hasegawa

Translational Research and Biomarkers

MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma

Junji Kurashige, Hidenobu Kamohara, Masayuki Watanabe, Yukiharu Hiyoshi, Masaaki Iwatsuki, Youhei Tanaka, Koichi Kinoshita, Seiya Saito, Yoshifumi Baba, Hideo Baba

Translational Research and Biomarkers

A Novel Genetically Modified Oncolytic Vaccinia Virus in Experimental Models is Effective Against a Wide Range of Human Cancers

Dana Haddad, Nanhai Chen, Qian Zhang, Chun-Hao Chen, Yong A. Yu, Lorena Gonzalez, Jason Aguilar, Pingdong Li, Joyce Wong, Aladar A. Szalay, Yuman Fong

Open Access Translational Research and Biomarkers

Cell Cycle Proteins Predict Recurrence in Stage II and III Colon Cancer

Eric J. Th. Belt, Rebecca P. M. Brosens, Pien M. Delis-van Diemen, Herman Bril, Marianne Tijssen, Dirk F. van Essen, Martijn W. Heymans, Jeroen A. M. Beliën, Hein B. A. C. Stockmann, Sybren Meijer, Gerrit A. Meijer

Update Chirurgie

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S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.