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Annals of Surgical Oncology

Ausgabe 8/2021

Inhalt (110 Artikel)

Hepatobiliary Tumors

Chemotherapy-Associated Liver Injuries: Unmet Needs and New Insights for Surgical Oncologists

Luca Vigano, Martina Sollini, Francesca Ieva, Francesco Fiz, Guido Torzilli

Global Health Services Research

Cultural Complications Curriculum: Applicability to Surgical Oncology Programs and Practices

Alison S. Baskin, Lesly A. Dossett, Chelsea A. Harris

Global Health Services Research

Introducing the Ongoing Clinical Trials in the Surgical Oncology Series

Jonathan M. Hernandez, Kelly M. McMasters

ASO Research Letter

Circulating Tumor DNA as a Predictive Biomarker in Adjuvant Chemotherapy for Patients with Stage 2A Colon Cancer (COBRA)

Emily A. Verbus, Alexander J. Rossi, Allen J. Luna, Atif Iqbal, Van K. Morris, Jonathan M. Hernandez

ASO Research Letter

Pepinemab (Anti-SEMA4D) in Combination with Ipilimumab or Nivolumab for Patients with Resectable Pancreatic and Colorectal Cancer

Alexander J. Rossi, Tahsin M. Khan, Hanna Hong, Gregory B. Lesinski, Christina Wu, Jonathan M. Hernandez

ASO Research Letter

The Role of Liver Resection for Patients with Liver and Unresectable Lung Colorectal Metastases (LUNA)

Tahsin M. Khan, Emily A. Verbus, Shahyan U. Rehman, Yun Shin Chun, Jonathan M. Hernandez

Pancreatic Tumors

The Landmark Series: Preoperative Therapy for Pancreatic Cancer

Sameer H. Patel, Matthew H. G. Katz, Syed A. Ahmad

Peritoneal Surface Malignancy

The Landmark Series: Surgical Treatment of Colorectal Cancer Peritoneal Metastases

Lana Bijelic, Isabel Ramos, Diane Goeré

Gastrointestinal Oncology

Role of Radiation Therapy in Gastric Cancer

Sweet Ping Ng, Trevor Leong

Hepatobiliary Tumors

The Landmark Series: Hilar Cholangiocarcinoma

Kevin C. Soares, William R. Jarnagin

ASO Author Reflections

ASO Author Reflections: Hilar Cholangiocarcinoma

Kevin C. Soares, William R. Jarnagin

Pancreatic Tumors

The Landmark Series: Locally Advanced Pancreatic Cancer and Ablative Therapy Options

Rebekah R. White, James D. Murphy, Robert C. G. Martin

ASO Visual Abstract

ASO Visual Abstract: The Landmark Series—Minimally Invasive Pancreatic Resection

J. van Hilst, N. de Graaf, M. Abu Hilal, M. G. Besselink

Global Health Services Research

Patient and Caregiver Considerations and Priorities When Selecting Hospitals for Complex Cancer Care

Zhi Ven Fong, Pei-Wen Lim, Ryan Hendrix, Carlos Fernandez-del Castillo, Ryan D. Nipp, James M. Lindberg, Giles F. Whalen, William Kastrinakis, Motaz Qadan, Cristina R. Ferrone, Andrew L. Warshaw, Keith D. Lillemoe, David C. Chang, Lara N. Traeger

Global Health Services Research

National Institutes of Health Research Funding to Academic Surgical Oncologists: Who Are We and Where Do We Stand?

Jose Wilson Mesquita-Neto, Jayanth Manoharan, William Dailey, Francis I. Macedo, Nipun B. Merchant

ASO Author Reflections

ASO Author Reflections: National Institutes of Health Funding to Surgical Oncology Research

Jose Wilson Mesquita-Neto, Francis I. Macedo, Nipun B. Merchant

Hepatobiliary Tumors

Defining the Risk of Early Recurrence Following Curative-Intent Resection for Distal Cholangiocarcinoma

Kota Sahara, Diamantis I. Tsilimigras, Junya Toyoda, Kentaro Miyake, Cecilia G. Ethun, Shishir K. Maithel, Daniel E. Abbott, George A. Poultsides, Ioannis Hatzaras, Ryan C. Fields, Matthew Weiss, Charles Scoggins, Chelsea A. Isom, Kamran Idrees, Perry Shen, Yasuhiro Yabushita, Ryusei Matsuyama, Itaru Endo, Timothy M. Pawlik

Hepatobiliary Tumors

Assessment of the Long-Term Impact of Pancreatoduodenectomy on Health-Related Quality of Life Using the EORTC QLQ-PAN26 Module

Zhi Ven Fong, Yurie Sekigami, Motaz Qadan, Carlos Fernandez-del Castillo, Andrew L. Warshaw, Keith D. Lillemoe, Cristina R. Ferrone

Breast Oncology

Survival Outcomes for Metaplastic Breast Cancer Differ by Histologic Subtype

Audree B. Tadros, Varadan Sevilimedu, Dilip D. Giri, Emily C. Zabor, Monica Morrow, George Plitas

Breast Oncology

Concordance Between 21-Gene Recurrence Scores in Multifocal or Multicentric Breast Carcinomas Differs by Age and Histologic Subtype

Kate R. Pawloski, Hannah Y. Wen, Audree B. Tadros, Kelly Abbate, Monica Morrow, Mahmoud El-Tamer

Breast Oncology

The Role of Mastectomy in De Novo Stage IV Inflammatory Breast Cancer

Natalia Partain, Lauren M. Postlewait, Mediget Teshome, Kelly Rosso, Carolyn Hall, Juhee Song, Salyna Meas, Sarah M. DeSnyder, Bora Lim, Vicente Valero, Wendy Woodward, Naoto T. Ueno, Henry Kuerer, Anthony Lucci

Breast Oncology

Prospective Registry Trial Assessing the Use of Magnetic Seeds to Locate Clipped Nodes After Neoadjuvant Chemotherapy for Breast Cancer Patients

Janine M. Simons, Marion E. Scoggins, Henry M. Kuerer, Savitri Krishnamurthy, Wei T. Yang, Aysegul A. Sahin, Yu Shen, Heather Lin, Isabelle Bedrosian, Elizabeth A. Mittendorf, Alastair Thompson, Deanna L. Lane, Kelly K. Hunt, Abigail S. Caudle

Breast Oncology

Oncologic Safety of Nipple-Sparing Mastectomy in Patients with Breast Cancer and Tumor-to-Nipple Distance ≤ 1 cm: A Matched Cohort Study

Zhen-Yu Wu, Hee Jeong Kim, Jongwon Lee, Il Yong Chung, Jisun Kim, Sae-Byul Lee, Byung-Ho Son, Jing Han, Hyun Ho Han, Jin-Sup Eom, Sung-Bae Kim, Kyung Hae Jung, Gyungyub Gong, Hak Hee Kim, Sei-Hyun Ahn, BeomSeok Ko

ASO Author Reflections

ASO Author Reflections: Do Shorter Tumor-to-Nipple Distances Compromise the Local Oncologic Safety of Nipple-Sparing Mastectomy?

Zhen-Yu Wu, Jing Han, Jin Sup Eom, Sei-Hyun Ahn, BeomSeok Ko

Breast Oncology

Use of the Twelve-Gene Recurrence Score for Ductal Carcinoma in Situ and Its Influence on Receipt of Adjuvant Radiation and Hormonal Therapy

Mara A. Piltin, Tanya L. Hoskin, Courtney N. Day, Dean A. Shumway, Elizabeth B. Habermann, John Davis, Judy C. Boughey

Breast Oncology

Personalized Screening for Breast Cancer: Rationale, Present Practices, and Future Directions

Tanir M. Allweis, Naama Hermann, Rinat Berenstein-Molho, Michal Guindy

ASO Author Reflections

ASO Author Reflections: Will Breast Cancer Screening Become Personalized?

Tanir M. Allweis, Naama Hermann

Colorectal Cancer

Neutrophil-to-Lymphocyte Ratio Predicts Recurrence Pattern in Patients with Resectable Colorectal Liver Metastases

Eden Verter, Yael Berger, Gali Perl, Idit Peretz, Ana Tovar, Sara Morgenstern, Baruch Brenner, Daniel Benchimol, Hanoch Kashtan, Eran Sadot

ASO Visual Abstract

ASO Visual Abstract: Neutrophil-to-Lymphocyte Ratio Predicts Recurrence Pattern in Patients with Resectable Colorectal Liver Metastases

Eden Verter, Yael Berger, Gali Perl, Idit Peretz, Ana Tovar, Sara Morgenstern, Baruch Brenner, Daniel Benchimol, Hanoch Kashtan, Eran Sadot

Open Access Endocrine Tumors

Total Thyroidectomy Versus Lobectomy for Thyroid Cancer: Single-Center Data and Literature Review

Carla Colombo, Simone De Leo, Marta Di Stefano, Matteo Trevisan, Claudia Moneta, Leonardo Vicentini, Laura Fugazzola

ASO Author Reflections

ASO Author Reflections: Total Thyroidectomy Versus Lobectomy for Differentiated Thyroid Cancer

Carla Colombo, Simone De Leo, Laura Fugazzola

Endocrine Tumors

Software-Based Analysis of the Taller-Than-Wide Feature of High-Risk Thyroid Nodules

Ming-Hsun Wu, Kuen-Yuan Chen, Argon Chen, Chiung-Nien Chen

Endocrine Tumors

Construction and Validation of a Nomogram Based on the Log Odds of Positive Lymph Nodes to Predict the Prognosis of Medullary Thyroid Carcinoma After Surgery

Jiajia Tang, Shitao Jiang, Luying Gao, Xuehua Xi, Ruina Zhao, Xingjian Lai, Bo Zhang, Yuxin Jiang

ASO Author Reflections

ASO Author Reflections: The Prognostic Significance of LODDS in Medullary Thyroid Carcinoma

Jiajia Tang, Shitao Jiang, Bo Zhang, Yuxin Jiang

Endocrine Tumors

Impact of Dyslipidemia on the Risk of Second Cancer in Thyroid Cancer Patients: A Korean National Cohort Study

Joon Ho, Eunhwa Kim, Minkyung Han, Inkyung Jung, Jandee Lee, Young Suk Jo

ASO Author Reflections

ASO Author Reflection: The Effect of Dyslipidemia on the Occurrence of Secondary Cancer in Patients With thyroid Cancer

Joon Ho, Eunhwa Kim, Minkyung Han, Inkyung Jung, Jandee Lee, Young Suk Jo

Open Access Endocrine Tumors

Complications After Major Surgery for Duodenopancreatic Neuroendocrine Tumors in Patients with MEN1: Results from a Nationwide Cohort

Dirk-Jan van Beek, Sjoerd Nell, Wessel M. C. M. Vorselaars, Bert A. Bonsing, Casper H. J. van Eijck, Harry van Goor, Elisabeth J. Nieveen van Dijkum, Cornelis H. C. Dejong, Gerlof D. Valk, P. H. Bisschop, O. M. Dekkers, M. L. Drent, B. Havekes, W. W. de Herder, A. N. A. van der Horst-Schrivers, C. R. C. Pieterman, A. C. van de Ven, Inne H. M. Borel Rinkes, Menno R. Vriens

Open Access ASO Author Reflections

ASO Author Reflections: Severe Morbidity After Major Surgery in Patients with MEN1

Dirk-Jan van Beek, Wessel M. C. M. Vorselaars, Inne H. M. Borel Rinkes, Menno R. Vriens

Gastrointestinal Oncology

Thoracic Duct Resection Has a Favorable Impact on Prognosis by Preventing Hematogenous Spread of Esophageal Cancer Cells: A Multi-institutional Analysis of 2269 Patients

Koji Tanaka, Makoto Yamasaki, Keijiro Sugimura, Osamu Shiraishi, Masaaki Motoori, Takuya Hamakawa, Atsushi Takeno, Kotaro Yamashita, Tomoki Makino, Yutaka Kimura, Hiroshi Miyata, Motohiro Hirao, Hidetoshi Eguchi, Takushi Yasuda, Masahiko Yano, Yuichiro Doki

ASO Author Reflections

ASO Author Reflection: Impact of Thoracic Duct Resection on Prognosis After Esophageal Cancer Surgery

Koji Tanaka, Makoto Yamasaki, Yuichiro Doki

Gastrointestinal Oncology

Effect of Additional Trastuzumab in Neoadjuvant and Adjuvant Treatment for Patients with Resectable HER2-Positive Gastric Cancer

Qifei He, Jiahui Chen, Kai Zhou, Chenggen Jin, Anqiang Wang, Ke Ji, Xin Ji, Ji Zhang, Xiaojiang Wu, Xia Li, Zhaode Bu, Jiafu Ji

Gastrointestinal Oncology

Treatment at an Academic Cancer Center Confers Better Survival by Stage for Signet-Ring Cell and Non-signet-Ring Cell Gastric Cancer

Maitham A. Moslim, Michael J. Minarich, Mengying Deng, Elizabeth Handorf, Stephanie H. Greco, Sanjay S. Reddy, Jeffrey M. Farma

Gastrointestinal Oncology

Cytoreductive Surgery for Selected Patients Whose Metastatic Gastric Cancer was Treated with Systemic Chemotherapy

Yaniv Berger, Mihai Giurcanu, Charles C. Vining, Darryl Schuitevoerder, Mitchell C. Posner, Kevin K. Roggin, Blase N. Polite, Chih-Yi Liao, Oliver S. Eng, Daniel V. T. Catenacci, Kiran K. Turaga

Gastrointestinal Oncology

Impact of the Interval Between Neoadjuvant Chemotherapy and Gastrectomy on Short- and Long-Term Outcomes for Patients with Advanced Gastric Cancer

Augustinas Bausys, Toomas Ümarik, Martynas Luksta, Arvo Reinsoo, Rokas Rackauskas, Giedre Anglickiene, Marius Kryzauskas, Kristina Tõnismäe, Veslava Senina, Dmitrij Seinin, Rimantas Bausys, Kestutis Strupas

Gastrointestinal Oncology

Appropriate Number of Adjuvant Chemotherapy Cycles for Patients with Stage 2 or 3 Gastric Cancer After Curative Gastrectomy: A Multicenter Cohort Study

Sang-Ho Jeong, Moon-Won Yoo, Young-Gil Son, Sung Jin Oh, Jong-Han Kim, Hyoung-Il Kim, Joong-Min Park, Hoon Hur, Ye Seob Jee, Sun-Hwi Hwang, Sung-Ho Jin, Sang Eok Lee, Yong-Joon Lee, Kyung Won Seo, Sungsoo Park, Chang Min Lee, Chang Hyun Kim, In Ho Jeong, Han Hong Lee, Sung Il Choi, Sang-Il Lee, Chan Young Kim, Hyundong Chae, Myoung-Won Son, Kyung Ho Pak, Sungsoo Kim, Moon-Soo Lee, Jae-Seok Min

Gastrointestinal Oncology

Prediction Model for Screening Patients at Risk of Malnutrition After Gastric Cancer Surgery

Ji-Hyeon Park, Eunjung Kim, Eun-Mi Seol, Seong-Ho Kong, Do Joong Park, Han-Kwang Yang, Jong-Ho Choi, Shin-Hoo Park, Hwi-Nyeong Choe, Meera Kweon, Jiwon Park, Yunhee Choi, Hyuk-Joon Lee

Open Access Gastrointestinal Oncology

Failure to Cure in Patients Undergoing Surgery for Gastric Cancer: A Nationwide Cohort Study

Daan M. Voeten, Leonie R. van der Werf, Janneke A. Wilschut, Linde A. D. Busweiler, Johanna W. van Sandick, Richard van Hillegersberg, Mark I. van Berge Henegouwen

Open Access ASO Author Reflections

ASO Author Reflections: Failure to Cure in Patients Undergoing Surgery for Gastric Cancer: A Nationwide Cohort Study

Daan M. Voeten, Mark I. van Berge Henegouwen

Gastrointestinal Oncology

Impact of Perioperative Blood Transfusions on Outcomes After Hyperthermic Intraperitoneal Chemotherapy: A Propensity-Matched Analysis

Boateng Kubi, Richard Nudotor, Nadege Fackche, Wasay Nizam, Jordan M. Cloyd, Travis E. Grotz, Keith F. Fournier, Sean P. Dineen, Benjamin D. Powers, Jula Veerapong, Joel M. Baumgartner, Callisia N. Clarke, Sameer H. Patel, Laura A. Lambert, Daniel E. Abbott, Kara A. Vande Walle, Mustafa Raoof, Byrne Lee, Shishir K. Maithel, Charles A. Staley, Fabian M. Johnston, Jonathan B. Greer

Thoracic Oncology

Validation of the 8th Edition Nodal Staging and Proposal of New Nodal Categories for Future Editions of the TNM Classification of Non-Small Cell Lung Cancer

Shaolei Li, Shi Yan, Fangliang Lu, Chao Lv, Yaqi Wang, Xiang Li, Yuzhao Wang, Yue Yang, Nan Wu

Thoracic Oncology

Impact of Lymph Node Ratio on Survival Outcome in Esophageal Squamous Cell Carcinoma After Minimally Invasive Esophagectomy

Yu Kitamura, Taro Oshikiri, Gosuke Takiguchi, Naoki Urakawa, Hiroshi Hasegawa, Masashi Yamamoto, Shingo Kanaji, Kimihiro Yamashita, Takeru Matsuda, Yasuhiro Fujino, Masahiro Tominaga, Tetsu Nakamura, Satoshi Suzuki, Yoshihiro Kakeji

Thoracic Oncology

The Impact of Pretherapeutic Naples Prognostic Score on Survival in Patients with Locally Advanced Esophageal Cancer

Kazuki Kano, Takanobu Yamada, Kouji Yamamoto, Keisuke Komori, Hayato Watanabe, Kosuke Takahashi, Hirohito Fujikawa, Toru Aoyama, Masakatsu Numata, Hiroshi Tamagawa, Norio Yukawa, Yasushi Rino, Munetaka Masuda, Takashi Ogata, Takashi Oshima

ASO Author Reflections

ASO Author Reflections: Pretherapeutic Naples Prognostic Score in Locally Advanced Esophageal Cancer

Kazuki Kano, Takanobu Yamada, Takashi Ogata, Takashi Oshima

Thoracic Oncology

Pulmonary Metastasectomy in Patients with Lung Metastases from Nasopharyngeal Carcinoma

Ze-Rui Zhao, Di-Han Liu, Yi-Zhi Wang, Xue‐Song Sun, Hao Long

Gynecologic Oncology

Multidisciplinary Surgical Approach to Increase Complete Cytoreduction Rates for Advanced Ovarian Cancer in a Tertiary Gynecologic Oncology Center

Karen M. Mulligan, Kate Glennon, Fionán Donohoe, Yvonne O’Brien, Brian C. Mc Donnell, Helena C. Bartels, Carolien Vermeulen, Tom Walsh, Conor Shields, Orla McCormack, John Conneely, William D. Boyd, Ruaidhrí Mc Vey, Jurgen Mulsow, Donal J. Brennan

Melanoma

Performance of Long-Term CT and PET/CT Surveillance for Detection of Distant Recurrence in Patients with Resected Stage IIIA–D Melanoma

Robin M. Turner, Mbathio Dieng, Nikita Khanna, Mai Nguyen, Jiaxu Zeng, Amanda A. G. Nijhuis, Omgo E. Nieweg, Andrew J. Einstein, Louise Emmett, Sarah J. Lord, Alexander M. Menzies, John F. Thompson, Robyn P. M. Saw, Rachael L. Morton

Melanoma

Evaluation of a Gene Expression Profiling Assay in Primary Cutaneous Melanoma

Aaron W. Kangas-Dick, Alissa Greenbaum, Victor Gall, Roman Groisberg, Janice Mehnert, Chunxia Chen, Dirk F. Moore, Adam C. Berger, Vadim Koshenkov

ASO Author Reflections

ASO Author Reflections: Gene Expression Profiling for Melanoma: Is it Ready for Prime Time?

Aaron Kangas-Dick, Adam C. Berger, Vadim Koshenkov

Pancreatic Tumors

Intraoperative Radiation Mitigates the Effect of Microscopically Positive Tumor Margins on Survival Among Pancreatic Adenocarcinoma Patients Treated with Neoadjuvant FOLFIRINOX and Chemoradiation

Yurie Sekigami, Theodoros Michelakos, Carlos Fernandez-del Castillo, Filippos Kontos, Motaz Qadan, Jennifer Y. Wo, Jon Harrison, Vikram Deshpande, Onofrio Catalano, Keith D. Lillemoe, Theodore S. Hong, Cristina R. Ferrone

Pancreatic Tumors

R Status is a Relevant Prognostic Factor for Recurrence and Survival After Pancreatic Head Resection for Ductal Adenocarcinoma

Stefano Crippa, Fabio Giannone, Marco Schiavo Lena, Giulio Belfiori, Stefano Partelli, Domenico Tamburrino, Roberto Delpini, Michele Pagnanelli, Nicolo Pecorelli, Gianpaolo Balzano, Claudio Doglioni, Massimo Falconi

Pancreatic Tumors

Measurement of Portal Vein Blood Circulating Tumor Cells is Safe and May Correlate With Outcomes in Resected Pancreatic Ductal Adenocarcinoma

Michael G. White, Andrew Lee, Diego Vicente, Carolyn Hall, Michael P. Kim, Matthew H. G. Katz, Jeffrey E. Lee, Naruhiko Ikoma, Anthony Lucci, Ching-Wei D. Tzeng

Pancreatic Tumors

Pancreatectomy with Vascular Resection After Neoadjuvant FOLFIRINOX: Who Survives More Than a Year After Surgery?

Jonathan Garnier, Fabien Robin, Jacques Ewald, Ugo Marchese, Damien Bergeat, Karim Boudjema, Jean-Robert Delpero, Laurent Sulpice, Olivier Turrini

ASO Author Reflections

ASO Author Reflections: Which Patient will Benefit from Complex Vascular Resection during Pancreatectomy?

Jonathan Garnier, Laurent Sulpice, Olivier Turrini

Peritoneal Surface Malignancy

Perioperative Management of Gastric Cancer Patients Treated With (Sub)Total Gastrectomy, Cytoreductive Surgery, and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Lessons Learned

W. J. Koemans, A. Houwink, R. T. van der Kaaij, E. C. E. Wassenaar, D. Boerma, C. Hahn, O. Imhof, M. G. Brandt, M. P. Ariëns, A. A. F. A. Veenhof, K. J. Hartemink, J. W. van Sandick

Peritoneal Surface Malignancy

Outcomes for Elderly Ovarian Cancer Patients Treated with Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC)

Katherin Zambrano-Vera, Armando Sardi, Felipe Lopez-Ramirez, Michelle Sittig, Carlos Munoz-Zuluaga, Carol Nieroda, Vadim Gushchin, Teresa Diaz-Montes

ASO Author Reflections

ASO Author Reflections: The Frailty of Patient Selection

Katherin Zambrano-Vera, Armando Sardi, Michelle Sittig, Teresa Diaz-Montes

Peritoneal Surface Malignancy

Impact of Surgical Modalities on Long-term Survival Outcomes of Patients with Duodenal Gastrointestinal Stromal Tumor

You-Zhu Wei, Zhi-Bin Cai, Chen-Long Zhu, Yan-Ming Zhou, Xiao-Feng Zhang

Peritoneal Surface Malignancy

Diaphragmatic Peritonectomy and Full-Thickness Resection in CRS/HIPEC May Allow Higher Completeness of Cytoreduction Rates with a Low Rate of Respiratory Complications

Andrea Craus-Miguel, Juan José Segura-Sampedro, Xavier González-Argenté, Rafael Morales-Soriano

ASO Author Reflections

ASO Author Reflections: Diaphragmatic Resection Often Is Needed in CRS/HIPEC But Does Not Increase Respiratory Complications

Juan José Segura-Sampedro, Andrea Craus-Miguel, Xavier González-Argenté, Rafael Morales-Soriano

Peritoneal Surface Malignancy

A Multi-institutional Study of Peritoneal Recurrence Following Resection of Low-grade Appendiceal Mucinous Neoplasms

Joel M. Baumgartner, Amitabh Srivastava, Nelya Melnitchouk, Michael G. Drage, Aaron R. Huber, Raul S. Gonzalez, Phoenix Bell, Elizabeth Wu, Murray Resnick, Kiran Turaga, Elizabeth Poli, Jesus Esquivel, Jeremiah Deneve, Kaitlyn J. Kelly, Jula Veerapong, Andrew M. Lowy

Sarcoma

Lymphadenopathy in Fungating Extremity Soft-Tissue Sarcoma: Metastasis or Reactive?

Nicholas M. Siegel, Santiago A. Lozano-Calderón, Jad M. El Abiad, Carol D. Morris, Adam S. Levin

Sarcoma

Unplanned Excision of Extremity and Trunk Wall Soft Tissue Sarcoma: To Re-resect or Not to Re-resect?

Maria Danieli, Francesco Barretta, Marco Fiore, Stefano Radaelli, Claudia Sangalli, Marta Barisella, Silvia Stacchiotti, Elena Palassini, Rosalba Miceli, Dario Callegaro, Paolo Giovanni Casali, Alessandro Gronchi

Translational Research

SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells

Masakatsu Paku, Naotsugu Haraguchi, Mitsunobu Takeda, Shiki Fujino, Takayuki Ogino, Hidekazu Takahashi, Norikatsu Miyoshi, Mamoru Uemura, Tunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi

Translational Research

High ARHGEF2 (GEF-H1) Expression is Associated with Poor Prognosis Via Cell Cycle Regulation in Patients with Pancreatic Cancer

Yosuke Nakao, Shigeki Nakagawa, Yo-ichi Yamashita, Naoki Umezaki, Yuya Okamoto, Yoko Ogata, Noriko Yasuda-Yoshihara, Rumi Itoyama, Toshihiko Yusa, Kohei Yamashita, Tatsunori Miyata, Hirohisa Okabe, Hiromitsu Hayashi, Katsunori Imai, Hideo Baba

Translational Research

Impact of Preoperative Circulating Tumor DNA Status on Survival Outcomes After Hepatectomy for Resectable Colorectal Liver Metastases

Shin Kobayashi, Yoshiaki Nakamura, Hiroya Taniguchi, Justin I. Odegaard, Shogo Nomura, Motohiro Kojima, Motokazu Sugimoto, Masaru Konishi, Naoto Gotohda, Shinichiro Takahashi, Takayuki Yoshino

Update Chirurgie

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S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.