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01.12.2015 | Research article | Ausgabe 1/2015 Open Access

BMC Musculoskeletal Disorders 1/2015

Anterior cervical discectomy and fusion may be more effective than anterior cervical corpectomy and fusion for the treatment of cervical spondylotic myelopathy

Zeitschrift:
BMC Musculoskeletal Disorders > Ausgabe 1/2015
Autoren:
Li Guan, Yong Hai, Jin-Cai Yang, Li-Jin Zhou, Xiao-Long Chen
Wichtige Hinweise

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

Li Guan designed the study, conceived and supervised the study, performed the examination and the analysis and drafted the paper. Yong Hai conceived and supervised the study, performed the statistical analysis and interpreted the results. Jin-Cai Yang performed the examination and the analysis, performed the statistical analysis and interpreted the results. Li-Jin Zhou performed the statistical analysis and revised the paper. and Xiao-Long Chen drafted the paper and revised the paper. All authors read and approved the final paper.

Abstract

Background

This meta-analysis explored the efficacy and safety of anterior cervical corpectomy and fusion (ACCF) comparing to anterior cervical discectomy and fusion (ACDF) in treating cervical spondylotic myelopathy (CSM) patients.

Methods

Several electronic databases were searched combined with manually searching. Thirteen randomized controlled studies were enrolled with 1,062 CSM patients, including 468 patients and 594 patients in the in the ACCF and ACDF group, respectively. The meta-analysis was then performed using the STATA 12.0 software. Crude standard mean difference (SMD) or odds ratio (OR) with their 95% confidence intervals (CI) were calculated.

Results

Our meta-analysis results revealed that CSM patients in ACDF group showed less blood loss than those in ACCF group (SMD = 1.21, 95% CI = 1.03 ~ 1.39, P < 0.001). The operation time of CSM patients in the ACDF group was also obviously shorter than those in ACCF group (SMD = 0.40, 95% CI = 0.23 ~ 0.57, P < 0.001). Furthermore, CSM patients in ACDF group had shorter hospital time than those in ACCF group (SMD = 0.45, 95% CI = 0.21 ~ 0.69, P < 0.001).

Conclusion

Our findings provide empirical evidence that ACDF may be more effective than ACCF for CSM treatment.
Literatur
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