Introduction
Materials and methods
Results
Authors | Years | Age | Sex | Hearing loss | Headache | Facial paralysis | Cranial nerves or other sites involvement | Serum ANCA | MRI | Operation or biopsy | Primary treatment | Symptom improvement | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MPO–ANCA | PR3-ANCA | ||||||||||||
Ishii et al. [9] | 1991 | 55 | F | Left MHL | ND | Left | + | ND | ND | + | Craniotomy | Prednisolone and antibiotics | Yes |
Murai et al. [10] | 1992 | 59 | F | Bilateral MHL | + | Bilateral | ND | ND | ND | + | No | Miconazole, flucytosin and fluconazole (otorrhea culture: Aspergillus flavus) | Yes |
Oku et al. [11] | 1995 | 52 | F | Right CHL | + | − | ND | ND | ND | + | Right suboccipital craniectomy | Corticosteroid | Yes |
Adachi et al. [12] | 1995 | 67 | F | Right MHL | + | Left | + | ND | ND | + | Biopsy of the epidural mass of T5 | Antibiotics | Yes |
Yi et al. [13] | 2000 | 26 | M | Right MHL | + | Right | + | ND | ND | + | Mastoidectomy and labyrinthectomy | Antibiotics (otorrhea culture: Staphylococcus) | Yes |
Kanzaki et al. [14] | 2004 | 70 | F | Bilateral MHL | ND | Bilateral | + | − | − | + | Mastoidectomy | Hydrocortisone and Vancomycin (otorrhea culture: MRSA) | Yes |
Sato et al. [15] | 2004 | 65 | F | Right MHL | + | ND | + | ND | ND | + | ND | Antibiotics | Yes |
Tada et al. [16] | 2006 | 54 | M | Bilateral SHL | + | ND | + | ND | ND | + | Biopsy of the dura matter, lung, skin and nasal mucosa | Corticosteroid and cyclophosphamide | Yes |
*Iwasaki et al. [17] | 2006 | 36 | F | Left CHL | + | − | + | − | − | + | Craniotomy | Prednisolone | Yes |
54 | M | Right CHL | + | Right | + | − | − | + | Craniotomy | Prednisolone | Yes | ||
67 | M | Left CHL | + | − | + | − | + | + | No | Methylprednisolone and prednisolone | Yes | ||
54 | F | Left MHL | + | − | + | − | − | + | No | Prednisolone | Yes | ||
72 | M | Right MHL | + | Right | + | − | − | + | Craniotomy | Corticosteroid | Yes | ||
67 | F | Left MHL | + | − | + | − | − | + | Craniotomy | Prednisolone and azathioprine | Yes | ||
Bravo et al. [18] | 2007 | 53 | M | CHL | + | − | + | ND | ND | + | Mastoidectomy and biopsy of dura matter | Methylprednisolone, antibiotics, and methotrexate | Yes |
Lu et al. [19] | 2009 | 51 | F | Right MHL | + | Right | + | ND | ND | + | Biopsy of tentorium cerebelli and nasopharynx | Corticosteroid and antibiotics | Yes |
Kobayakawa et al. [20] | 2010 | 70 | F | Left CHL | + | − | ND | ND | ND | + | Mastoidectomy and tympanoplasty | Corticosteroid and antibiotics | Recurrence |
*Hasegawa et al. [21] | 2012 | 48 | M | Bilateral MHL | + | Left | + | + | − | + | Pharyngeal biopsy | Prednisolone and cyclophosphamide | Yes |
Keshavaraj et al. [23] | 2012 | 40 | F | MHL | + | − | + | − | − | + | Craniotomy | Corticosteroid | Yes |
*Mori et al. [22] | 2013 | 63 | M | Bilateral MHL | + | Bilateral | + | + | − | + | ND | Antibiotics, corticosteroid and immunoglobulin | Recurrence |
*Saito et al. [24] | 2014 | 72 | F | Bilateral MHL | + | ND | + | + | − | + | ND | Corticosteroid and immunosuppressant | Yes |
Okada et al. [25] | 2015 | 63 | M | Left MHL | + | − | + | − | − | + | Mastoidectomy and tympanostomy tube insertion | Antibiotics and voriconazole | Yes |
Fujimoto et al. [26] | 1993 | 4 patients were reported with HP and OM. They showed multiple cranial nerves involvement. Of which, 3 patients received corticosteroid and the symptoms improved | |||||||||||
*Yokoseki et al. [27] | 2014 | 21 patients were reported with ANCA-related HP. More than 75% patients had hearing loss. Profound hearing impairment was common. Steroid plus immunosuppressant was very effective | |||||||||||
*Harabuchi et al. [8] | 2017 | They performed a retrospective analysis of 235 patients classified as OMAAV in Japan. 28% of patients were reported with HP. MPO-ANCA positivity was common. 60% patients received steroid plus immunosuppressant, and nearly half of patients had disease relapse |