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International Urogynecology Journal

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26.08.2020 | Review Article

Antibiotic prophylaxis for urodynamic testing in women: a systematic review

Erschienen in: International Urogynecology Journal | Ausgabe 1/2021

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Abstract

Introduction and hypothesis

Urinary tract infection is the most common complication after urodynamic studies (UDS). Practice guidelines recommend against antibiotic prophylaxis based on an outdated review of the literature, which advised on the premise of “a lack of good quality studies” and based on an assumed low incidence not consistently supported by the literature.

Objectives

This systematic review aims to update the assessment of the efficacy of antibiotic prophylaxis compared with placebo or no treatment for prevention of urinary tract infection in females over the age of 18 years undergoing UDS.

Methods

MEDLINE, EMBASE, COCHRANE, DISSERTATIONS, conference proceedings and clinical trial registries were searched for relevant randomized controlled trials. Two authors independently screened and selected articles, assessed these for quality according to Cochrane guidelines and extracted their data.

Results

A total of 2633 records were screened, identifying three relevant randomized controlled trials. The one study that was critically appraised as being the least likely biased showed a statistically significant effect of antibiotic prophylaxis in reducing bacteriuria post UDS in female patients. The other two studies included in the review did not. None of the studies included were powered to show a significant change in the incidence of urinary tract infection following UDS in female patients receiving antibiotic prophylaxis versus no prophylaxis.

Conclusions

Similar to the 2012 Cochrane review on this subject, this systematic review demonstrated that antibiotic prophylaxis may decrease bacteriuria in women post UDS; however, further research is required to assess its effect on urinary tract infections in this context.

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Titel: Antibiotic prophylaxis for urodynamic testing in women: a systematic review
Publikationsdatum: 26.08.2020
Erschienen in: International Urogynecology Journal / Ausgabe 1/2021
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-020-04501-3

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Springer Medizin

Antibiotic prophylaxis for urodynamic testing in women: a systematic review

Abstract

Introduction and hypothesis

Objectives

Methods

Results

Conclusions

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Springer Medizin

Abstract

Introduction and hypothesis

Objectives

Methods

Results

Conclusions

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