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International Urogynecology Journal

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13.01.2017 | Original Article

Anticholinergic prescription: are healthcare professionals the real burden?

verfasst von: George Araklitis, Ganesh Thiagamoorthy, Jo Hunter, Angie Rantell, Dudley Robinson, Linda Cardozo

Erschienen in: International Urogynecology Journal | Ausgabe 8/2017

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Abstract

Introduction and hypothesis

Anticholinergic medication is the medical treatment for overactive bladder (OAB). These drugs can act on the central nervous system and can lead to cognitive decline, dementia, and potentially death. Patients taking drugs with anticholinergic effects increase their anticholinergic burden—defined as the cumulative effect of taking one or more drugs that can have adverse effects. When prescribing anticholinergic medication for the elderly, we must choose the right drug. We aimed to discover the level of understanding on this subject and its application to real clinical practice amongst our healthcare professionals (HCPs).

Methods

An 18-point questionnaire was distributed to urogynaecologists, general gynaecologists, urologists, geriatricians, general practitioners (GPs), and nurse specialists to assess knowledge on the subject.

Results

A total of 96 HCPs completed the questionnaire. The nurse specialists had the highest score in identifying that oxybutynin was the drug most likely to cross the blood–brain barrier (BBB). The urogynaecologists had the highest score in identifying that trospium chloride was least likely to cross the BBB, whereas the GPs had the lowest score. Solifenacin was the most popular anticholinergic drug prescribed in the elderly without dementia. Trospium chloride was the most popular drug prescribed in the elderly with dementia.

Conclusions

We have found that knowledge is lacking amongst all our HCPs, but especially amongst our first-line doctors, our GPs. Education is key in developing knowledge and safe prescribing, to improve the care we give to our patients.

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Titel: Anticholinergic prescription: are healthcare professionals the real burden?
verfasst von: George Araklitis
Ganesh Thiagamoorthy
Jo Hunter
Angie Rantell
Dudley Robinson
Linda Cardozo
Publikationsdatum: 13.01.2017
Verlag: Springer London
Erschienen in: International Urogynecology Journal / Ausgabe 8/2017
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-016-3258-3

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Anticholinergic prescription: are healthcare professionals the real burden?

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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