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Erschienen in:

2016 | OriginalPaper | Buchkapitel

5. Antigen- bzw. Allergenpräsentation

verfasst von : M. M. Epstein, Dr. med., G. Stingl, Prof. Dr. med., M.-C. Brüggen, Dr. med.

Erschienen in: Allergologie

Verlag: Springer Berlin Heidelberg

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Zusammenfassung

Die Aufnahme und Präsentation von Antigenen bzw. Allergenen durch antigenpräsentierende Zellen und insbesondere dendritische Zellen (DC) stellt eine Schlüsseletappe in der Pathogenese allergischer Erkrankungen dar. T-Zellen erkennen jedoch nicht Antigene per se sondern Komplexe, die aus Histokompatibilitätsantigenen (MHC-I oder MHC-II) und vom Proteinantigen herstammenden Peptiden zusammengesetzt sind und an der Oberfläche antigenpräsentierender Zellen zu finden sind. In diesem Kapitel werden als erstes die verschiedenen Mechanismen der Antigenpräsentation, d. h. MHC-I-, MHC-II-, und CD1-Präsentationswege, dargelegt. Darauf folgt eine Beschreibung der in der Haut sowie im Respirationstrakt residierenden Subpopulationen dendritischer Zellen. Die Bedeutung und die unterschiedlichen Rollen der DC-Subpopulationen werden anhand der Pathogenese des Kontaktekzems, der atopischen Dermatitis sowie des allergischen Asthmas illustriert.

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Titel: Antigen- bzw. Allergenpräsentation
verfasst von: M. M. Epstein, Dr. med.
G. Stingl, Prof. Dr. med.
M.-C. Brüggen, Dr. med.
Verlag: Springer Berlin Heidelberg
Buch: Allergologie
Print ISBN: 978-3-642-37202-5

Electronic ISBN: 978-3-642-37203-2

Copyright-Jahr: 2016
DOI: https://doi.org/10.1007/978-3-642-37203-2_5

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5. Antigen- bzw. Allergenpräsentation

Zusammenfassung

Neu im Fachgebiet HNO

HNO-Op. auch mit über 90?

Intrakapsuläre Tonsillektomie gewinnt an Boden

Bilateraler Hörsturz hat eine schlechte Prognose

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Zusammenfassung

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Neu im Fachgebiet HNO

HNO-Op. auch mit über 90?

Intrakapsuläre Tonsillektomie gewinnt an Boden

Bilateraler Hörsturz hat eine schlechte Prognose

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

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