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Current Oncology Reports

Erschienen in:

01.05.2020 | Breast Cancer (B Overmoyer, Section Editor)

Applying the New Guidelines of HER2 Testing in Breast Cancer

verfasst von: Huina Zhang, Ioana Moisini, Rana M. Ajabnoor, Bradley M. Turner, David G. Hicks

Erschienen in: Current Oncology Reports | Ausgabe 5/2020

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Abstract

Purpose of Review

The human epidermal growth factor receptor 2 (HER2) is an important prognostic and predictive biomarker in the breast cancer. The American Society of Clinical Oncology/College of American Pathology (ASCO/CAP) has published HER2 testing guidelines in breast cancer. We herein reviewed the HER2 testing guidelines in breast cancer with a focus on the application of the current guidelines.

Recent Findings

The continual investigation of HER2 testing in breast cancer has resulted in updates in the HER2 testing guidelines. The current guidelines focus on the uncommon clinical scenarios and emphasize the coordination between immunohistochemistry and in situ hybridization results, in an effort to improve clarity and accuracy.

Summary

The ASCO/CAP guidelines provide valuable recommendations to ensure the accurate evaluation of HER2 status in breast cancer patients through standardization. Additional studies, particularly those with long-term outcome data are still needed to validate the guideline recommendations, especially the uncommon cases.

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Titel: Applying the New Guidelines of HER2 Testing in Breast Cancer
verfasst von: Huina Zhang
Ioana Moisini
Rana M. Ajabnoor
Bradley M. Turner
David G. Hicks
Publikationsdatum: 01.05.2020
Verlag: Springer US
Erschienen in: Current Oncology Reports / Ausgabe 5/2020
Print ISSN: 1523-3790
Elektronische ISSN: 1534-6269
DOI: https://doi.org/10.1007/s11912-020-0901-4

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Applying the New Guidelines of HER2 Testing in Breast Cancer

Abstract

Purpose of Review

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Recent Findings

Summary

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Weitere Artikel der Ausgabe 5/2020

Updates on Imaging of Liver Tumors

COVID-19 und Krebs: ein umfassender Überblick

Therapy of Peripheral T Cell Lymphoma: Focus on Nodal Subtypes

Percutaneous Management of Cancer Pain

New Targets in Lung Cancer (Excluding EGFR, ALK, ROS1)

Hyperprogressive Disease upon Immune Checkpoint Blockade: Focus on Non–small Cell Lung Cancer

Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie