Ausgabe 6/2023
Inhalt (25 Artikel)
ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis
- Review Article
Bingqing Wang, Yue Wang, Jing Zhang, Chang Hu, Jun Jiang, Yiming Li, ZhiYong Peng
Systematic review of genotoxicity induced by occupational exposure to antineoplastic drugs
- Review Article
Dorian Vanneste, Eline Verscheure, Adhithya Narayanan Srinivasan, Lode Godderis, Manosij Ghosh
Substance abuse and neurodegenerative diseases: focus on ferroptosis
- Review Article
Cheng Guo, Lei Chen, Yun Wang
Understanding the molecular mechanisms of statin pleiotropic effects
- Review Article
Charles A. German, James K. Liao
Next generation risk assessment of human exposure to estrogens using safe comparator compound values based on in vitro bioactivity assays
- Open Access
- Regulatory Toxicology
Tessa C. A. van Tongeren, Si Wang, Paul L. Carmichael, Ivonne M. C. M. Rietjens, Hequn Li
A comparison of the chemo- and radiotoxicity of thorium and uranium at different enrichment grades
- Open Access
- Inorganic Compounds
A. Rump, C. Hermann, A. Lamkowski, T. Popp, M. Port
Genetic variants of SOS2, MAP2K1 and RASGRF2 in the RAS pathway genes predict survival of HBV-related hepatocellular carcinoma patients
- Toxicogenomics and Omics Technologies
Qiuling Lin, Moqin Qiu, Xueyan Wei, Zhouyun xiang, Zihan Zhou, Iiangyan Ji, Xiumei Liang, Xianguo Zhou, Qiuping Wen, Yingchun Liu, Hongping Yu
Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes
- Molecular Toxicology
Kennedy M. Walls, Kyung U. Hong, David W. Hein
Dimeric oxyberberine CT4-1 targets LINC02331 to induce cytotoxicity and inhibit chemoresistance via suppressing Wnt/β-catenin signaling in hepatocellular carcinoma
- Molecular Toxicology
Xian Lin, Jian Chen, Xin Li, Dong Chen, Kaixuan Luo, Yongxing Deng, Dinghua Yang, Zunnan Huang, Cheng Tao
Organotin mixtures reveal interactions that modulate adipogenic differentiation in 3T3-L1 preadipocytes
- Molecular Toxicology
Elvis Ticiani, Yong Pu, Madison White, Victoria Adomshick, Almudena Veiga-Lopez
Exposure to dietary fatty acids oleic and palmitic acid alters structure and mechanotransduction of intestinal cells in vitro
- Open Access
- In vitro systems
Janice Bergen, Martina Karasova, Andrea Bileck, Marc Pignitter, Doris Marko, Christopher Gerner, Giorgia Del Favero
A new cell line based coculture system for skin sensitisation testing in one single assay using T cells, aryl hydrocarbon receptor knockout, and co-inhibitory blockage
- Open Access
- In vitro systems
Anna Sonnenburg, Ralf Stahlmann, Reinhold Kreutz, Matthias Peiser
Application of toxicology in silico methods for prediction of acute toxicity (LD50) for Novichoks
- Open Access
- In silico
Maciej Noga, Agata Michalska, Kamil Jurowski
In vitro to in vivo extrapolation and high-content imaging for simultaneous characterization of chemically induced liver steatosis and markers of hepatotoxicity
- Open Access
- Organ Toxicity and Mechanisms
Fabrice A. Müller, Marianna Stamou, Felix H. Englert, Ole Frenzel, Sabine Diedrich, Laura Suter-Dick, John F. Wambaugh, Shana J. Sturla
Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved
- Open Access
- Organ Toxicity and Mechanisms
Teresa Martínez-Sena, Erika Moro, Marta Moreno-Torres, Guillermo Quintás, Jan Hengstler, José V. Castell
Evaluation of functional candidate biomarkers of non-genotoxic hepatocarcinogenicity in human liver spheroid co-cultures
- Genotoxicity and Carcinogenicity
Bruna dos Santos Rodrigues, Kaat Leroy, Milos Mihajlovic, Sybren De Boever, Sarah Vanbellingen, Bruno Cogliati, Joeri L. Aerts, Mathieu Vinken
Induction of clastogenesis and gene mutations by carbamazepine (at its therapeutically effective serum levels) in mammalian cells and the dependence on human CYP2B6 enzyme activity
- Genotoxicity and Carcinogenicity
Yujian Wang, Yuting Chen, Yijing Chen, Wenwen Luo, Yungang Liu
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity
- Genotoxicity and Carcinogenicity
Mariam R. Habil, David W. Hein
Effect of N-acetyltransferase 2 genetic polymorphism on 4,4′-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress
- Genotoxicity and Carcinogenicity
Mariam R. Habil, Raúl A. Salazar-González, Mark A. Doll, David W. Hein
The tick saliva peptide HIDfsin2 promotes the tick-borne virus SFTSV replication in vitro by enhancing p38 signal pathway
- Biologics
Luyao Wang, Fang Sun, Jing Hu, Weimin Zuo, Yi Zheng, Yingliang Wu, Hang Fai Kwok, Zhijian Cao
Maternal exposure to multiple mycotoxins and adverse pregnancy outcomes: a prospective cohort study in rural Bangladesh
- Open Access
- Biologics
Nicholas N. A. Kyei, Jillian L. Waid, Nurshad Ali, Benedikt Cramer, Hans-Ulrich Humpf, Sabine Gabrysch
US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations
- Open Access
- Letter to the Editor, News and Views
Gio B. Gori, Michael Aschner, Christopher J. Borgert, Samuel M. Cohen, Daniel R. Dietrich, Corrado L. Galli, Helmut Greim, John S. Heslop-Harrison, Sam Kacew, Norbert E. Kaminski, James E. Klaunig, Hans W.J. Marquardt, Olavi Pelkonen, Ruth Roberts, Kai M. Savolainen, Aristidis Tsatsakis, Hiroshi Yamazaki
Health risks associated with dietary cadmium exposure
- Letter to the Editor, News and Views
Tomoyuki Kawada
Pharmacogenetics in early drug development for non-alcoholic steatohepatitis: missed chances and future opportunities
- Editorial
Joost Boeckmans, Alexandra Gatzios, Jörn M. Schattenberg, Robim M. Rodrigues, Vera Rogiers, Tamara Vanhaecke
Correction: In memoriam Thomas Gebel
- Open Access
- Correction
Jan G. Hengstler, Hermann Bolt, Uwe Heinrich, Andrea Hartwig, Robert Landsiedel
