This review considers firstly why we undertake invasive autopsies before considering present alternatives. It illustrates that with the exception of the so-called view and grant system, all present alternatives to a full necropsy have in some form or other an invasive component. It then considers the range of radiological techniques available to the modern forensic practitioner before considering whether computed tomography could have a role not only as an adjunct but as a complete replacement to an invasive autopsy. This truly non-invasive investigative technique may at last be a realistic alternative to invasive autopsy when undertaken in conjunction with an external examination of the body but at present only for certain types of death. However, is the forensic community ready for the adoption of this technology and what could be the consequences for future forensic pathologists?