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Erschienen in: Critical Care 3/2011

01.06.2011 | Commentary

Are we sedating more than just the brain?

verfasst von: Nathan E Brummel, Timothy D Girard

Erschienen in: Critical Care | Ausgabe 3/2011

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Abstract

Heavy sedation in the ICU is associated with coma, delirium, and prolonged stays, but links between sedatives and non-brain organ failure have rarely been described. In a post hoc analysis, Strøm and colleagues explored associations between sedation and acute kidney injury among ICU patients randomly assigned to one of two sedation strategies. The 'no sedation' protocol was associated with less kidney injury, but methodologic limitations preclude firm conclusions regarding mechanisms underlying this association. This hypothesis-generating study warns that sedation may harm organs other than the brain during critical illness, a possibility that warrants careful study in the future.
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Metadaten
Titel
Are we sedating more than just the brain?
verfasst von
Nathan E Brummel
Timothy D Girard
Publikationsdatum
01.06.2011
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 3/2011
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc10233