Ausgabe Sonderheft 1/2001
Innovative Rheumatology: Gene and Cell Therapies of Arthritis and Related Autoimmune Disorders. Second International Meeting
Inhalt (42 Artikel)
Adeno-associated virus preferentially transduces human compared to mouse synovium
K Jennings, S Katakura, H Burstein, G Gao, JM Wilson, R Hirsch
Engineering T cells and molecules for targeting joints and inflammation
Y Chernajovsky, A Annenkov, H Dreja, G Adams
Elimination of rheumatoid synovium in situ by Fas ligand 'gene scalpel™'
H Zhang, G Gao, G Clayburne, JM Wilson, HR Schumacher
Double and triple gene transfer in arthritis
U Müller-Ladner, E Neumann, M Fleck, T Pap, RE Gay, PD Robbins, JD Mountz, CH Evans, J Schölmerich, S Gay
Enhanced chondrocyte apoptosis leads to abnormal cartilage in rats and cats with glycosaminoglycan storage diseases
CM Simonaro, ME Haskins, EH Schuchman
Transfer of protease inhibitors to inhibit cartilage destruction
WH van der Laan, T Pap, PHA Quax, JM TeKoppele, FC Breedveld, S Gay, RE Gay, JH Verheijen, TWJ Huizinga
Local interleukin-12 gene transfer promotes conversion of an acute to a chronic destructive murine streptococcal cell wall arthritis
LAB Joosten, M Heuvelmans-Jacobs, E Lubberts, FAJ van de Loo, MMA Helsen, WB van den Berg
inflammation-inducible intra-articular production of human IL-1 receptor antagonist results in a more efficient inhibition of collagen-induced arthritis than does constitutive expression of the same transgene
AC Bakker, FAJ van de Loo, MB Bennink, LAB Joosten, AW Varley, RS Munford, WB van den Berg
Using a tropism-modified adenoviral vector for the intra-articular production of IL-1 receptor antagonist results in a more efficient inhibition of collagen-induced arthritis than does a conventional Ad5 vector
AC Bakker, FAJ van de Loo, OJ Arntz, LAB Joosten, I Dmitriev, V Krasnykh, DT Curiel, WB van den Berg
Delivery of antisense constructs and ribozymes to inhibit cartilage destruction in the SCID mouse model of RA
T Pap, J Schedel, U Müller-Ladner, RE Gay, W Zacharias, S Gay
Local IL-17 gene therapy accelerates collagen arthritis with severe bone erosion and rank ligand and rank expression in synovial infiltrate and at bone erosion sites
E Lubberts, LAB Joosten, P Schwarzenberger, B Oppers, L van de Bersselaar, JK Kolls, WB van den Berg
Update on the contralateral effect in rabbit and mouse models
PD Robbins, ER Lechman, S-H Kim, A Gambotto, J Whalen, SC Ghivizanni, CH Evans, Z Mi, TJ Oligino
Viral, nonviral and peptide-mediated intra-articular transfer of genes and proteins
PD Robbins, Z Mi, X Lu, J Mai, SC Ghivizanni, CH Evans, TJ Oligino
In vitro and in vivo differentiation of mesenchymal stem cells into chondrocytes
D Noël, F Apparailly, V Millet, J Sany, C Jorgensen
Inhibition of collagen-induced arthritis in mice by inducible AAV-mediated transfer of viral IL-10 gene
F Apparailly, V Millet, C Jacquet, J Sany, C Noël, C Jorgensen
Development of lentiviral vectors for gene therapy of arthritis
M Militello, F Apparailly, Y-L Lin, C Mettling, C Jorgensen, P Corbeau
Factors influencing adenoviral gene transfer
TWJ Huizinga, P Goossens, E Pieterman, R Vogels, M Havenga
Induction of synovial apoptosis by gene transfer and peptide mediated protein transduction
TJ Oligino, Q Yao, S Wang, JC Glorioso, CH Evans, SC Ghivizzani, R Takate, R Barton, PD Robbins
Targeted adenoviral vectors
E Vigne, A Brie, K Martin, A Gillardeaux, P Opolon, M Perricaudet, M Latta-Mahieu, JF Dedieu, P Yeh
A member of the T-box family of transcription factors mediates cartilage formation in mesenchymal progenitors C3H10T1/2
A Hoffmann, S Czichos, C Kaps, D Bächner, H Mayer, BG Kurkalli, Y Zilberman, D Gazit, G Gross
Clinical evaluation of autologous chondrocytes for joint repair
M Brittberg, E Sjögren-Jansson, L Peterson, A Lindahl
Adenoviral-based overexpression of TIMP-1 reduces tissue damage in the joints of TNF-alpha transgenic mice
G Schett, S Hayer, M Tohidast-Akrad, B Jahn-Schmid, S Lang, F Kainberger, G Kollias, AC Newby, Q Xu, G Steiner, JS Smolen
Therapeutic targeting of osteoclasts by osteoprotegerin and bisphosphonates leads to a reduction of TNFalpha-mediated bone resorption
K Redlich, S Hayer, CR Dunstan, M Tohidast-Akrad, S Lang, G Kollias, G Steiner, JS Smolen, G Schett
Gene therapy for cartilage healing
SC Ghivizzani, TJ Oligino, E Gouze-Decaris, G Palmer, PD Robbins, CH Evans
Transfer and intra-articular expression of the IL-1Ra cDNA in human rheumatoid joints
CH Evans, PD Robbins, SC Ghivizzani, JH Herndon, MC Wasko, M Tomaino, R Kang, TA Muzzonigro, EM Elder, TL Whiteside, SC Watkins
In vitro and in vivo gene delivery using a lentiviral vector
E Gouze-Decaris, R Pawliuk, C Pilapil, P Leboulch, CH Evans, SC Ghivizzani
Engineered cells and cartilage healing
T Häupl, C Kaps, G Gross, GR Burmester, M Sittinger
Autologous bone marrow grafting of avascular osteonecrosis before collapse
P Hernigou
Retrovirally-engineered antigen-specific T cells home to the inflamed joints and suppress collagen-induced arthrtis
A Nakajima, CM Seroogy, MR Sandora, IH Tarner, GL Costa, C Taylor-Edwards, MH Bachman, CH Contag, C Garrison-Fathman
Retroviral gene therapy of collagen-induced arthritis by local delivery of IL-4
IH Tarner, A Nakajima, CM Seroogy, J Ermann, MR Sandora, CH Contag, CG Fathman
Identification and expression of novel genes in osteoarthritis
D Bar, A Faerman, A Grossman, O Segev
Time-course of gene expression after electroporation in rat patellar chondrocytes
L Grossin, C Cournil, B Liagre, L Mir, S Etienne, C Guingamp, P Pottie, P Netter, P Gillet
Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivofrom mono-iodoacetate (MIA)-induced chondrocytes death
C Cournil, B Liagre, L Grossin, C Vol, A Abid, JY Jouzeau, B Terlain, P Netter, P Gillet
High efficiency intramuscular plasmid electrotransfer: application for sustained plasmatic secretion of cytokines
D Scherman, M Bettan, V Deleuze, P Kreiss, M Bureau
Osteoprotegerin (OPG) gene therapy in animal models of osteoarticular disease
B Bolon, C Carter, M Daris, S Morony, G Campagnuolo, U Feige, J Sheng
In vivoselection of synovial specific targets using phage display technology
C Pitzalis
Evidence for re-differentiation of human chondrocytes seeded on a hyaluronan derivative scaffold
B Grigolo, G Lisignoli, A Piacentini, M Fiorini, L Roseti, EO Major, M Duca, A Pavesio, A Facchini
AKT regulates TNF-alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts
JD Mountz, H-G Zhang, Y Wang, JF Xie, X Liang, H-C Hsu, DT Curiel
AAV mediated delivery of IL-4 prevents collagen-induced arthritis
N Bessis, M-C Boissier