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Arthritis Research & Therapy

Ausgabe Sonderheft 2/2001

21st European Workshop for Rheumatology Research

Inhalt (138 Artikel)

Meeting abstract

Protein microarray characterization of the autoantibody response in systemic lupus erythematosus and related diseases

W Robinson, C DiGennaro, W Hueber, D Fong, B Haab, D Hirshberg, S Muller, GJ Pruijn, WJ van Venrooij, JS Smolen, PO Brown, Lawrence Steinman, Paul J Utz

Meeting abstract

Genetic analysis of the pentraxin genes in SLE

AI Russell, CA Roberton, S Chadha, DS Cunninghame Graham, TJ Vyse

Meeting abstract

The role of DNA in the pathogenesis of SLE

DS Pisetsky

Meeting abstract

The place of mitochondria in apoptosis

G Kroemer

Meeting abstract

The pathogenesis of vasculitis

CGM Kallenberg

Meeting abstract

The molecular mechanism of osteoclastogenesis: ODF/RANKL-dependent and independent pathways

T Suda, N Takahashi, N Udagawa, C Miyaura

Meeting abstract

Anti-keratin antibodies in juvenile idiopathic arthritis

I Hromadnikova, P Vavrincova, K Stechova, D Hridelova, J Vavrinec

Meeting abstract

Clinical sensitivity of antibodies against cyclic citrulinated peptide in patients with rheumatoid arthritis

B Bozic, S Cucnik, A Ambrozic, B Lestan, M Kos-Golja, B Rozman B, T Kveder T

Meeting abstract

Expression of citrullin-containing antigens in RA synovium

TJ Smeets, ER Vossenaar, MC Kraan, WAM van Mansum, JM Raats, WJ van Venrooij, PP Tak

Meeting abstract

Autoreactivity patterns in rheumatoid arthritis

S Behrens, F Schumann, S Adelt, H Hofseß, R Bergholz, GR Burmester, JM Engel, S Bläß

Meeting abstract

Detection of rheumatoid arthritis-specific anti-filaggrin antibodies by line immunoassay shows complementarity to RF and corresponds to the AFA-blot using natural antigen

A Union, R Humbel, K Conrad, G Steiner, P Schmit, A Vos, K De Bosschere, S Dincq, H Pottel, L Meheus, L Nogueira, G Serre, F De Keyser

Meeting abstract

Investigation of the epitopes of human profilaggrin derived peptide targeted by antibodies of patient with rheumatoid arthritis

M Brozik, J Szakonyi, A Magyar, R Tóbi, B Rojkovich, F Hudecz, P Gergely

Meeting abstract

Anti-skin anti-intercellular antibodies in juvenile idiopathic arthritis

I Hromadnikova, P Vavrincova, K Stechova, D Hridelova, J Vavrinec

Meeting abstract

Aberrant expression of the autoantigen hnRNP-A2/RA33 in the joints of patients with rheumatoid arthritis and TNF-alpha transgenic mice: a clue to autoimmunity?

S Hayer, M Tohidast-Akrad, G Schett, K Skriner, D Plows, S Haralambos, G Kollias, J Smolen, G Steiner

Meeting abstract

Autoantibodies to the mRNA destabilizing protein hnRNP-D/AUF1 in patients with systemic autoimmune diseases

K Skriner, W Hueber, E Süleymanoglu, E Höfler, JS Smolen, G Steiner

Meeting abstract

The stress protein BiP is a major autoantigen in rheumatoid arthritis

U Neuhaus-Steinmetz, A Union, J Raymackers, F Schumann, S Behrens, W Schmid, JM Engel, GR Burmester, S Bläß

Meeting abstract

Lysozyme and its biological value in rheumatoid arthritis (RA)

J Smirnow, M Wislowska

Meeting abstract

Functional and biologic evaluation of immunoregulatory cytokines in the immunopathologic lesion of Sjogren's syndrome

DI Mitsias, AG Tzioufas, CI Veiopoulou, HM Moutsopoulos, G Thyphronitis

Meeting abstract

High spontaneous CD40 expression by salivary gland epithelial cells in Sjogren's syndrome: possible evidence for intrinsic activation of epithelial cells

ID Dimitriou, G Xanthou, EK Kapsogeorgou, RF Abu-Helu, HM Moutsopoulos, MN Manoussakis

Meeting abstract

Human neutrophil production and cleavage of IL-18: potentiating inflammatory arthritis?

SE Robertson, J Young, FY Liew, IB McInnes, JA Gracie

Meeting abstract

Intracellular expression of CXCR3 on rheumatoid arthritis synovial tissue cells

O Krystufkova, J Vencovsky, S Ruzickova, J Sinkora, J Niederlova, CA Power, C Plater-Zyberk

Meeting abstract

Interleukin-13 (IL-13)in autoimmune rheumatic diseases: relationship with autoantibody profile

T Rinaldi, A Spadaro, V Riccieri, E Taccari, G Valesini

Meeting abstract

Temporal expression of cytokines and chemokines in rat adjuvant-induced arthritis

Z Szekanecz, MM Halloran, JM Woods, MV Volin, GK Haines, AE Koch

Meeting abstract

Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis: a therapeutic study

K Palmblad, H Erlandsson Harris, KJ Tracey, U Andersson

Meeting abstract

Comparison of arthritogenic and nonarthritogenic Eubacterium aerofaciens cell walls

X Zhang, M Rimpiläinen, E Simelyte, P Toivanen

Meeting abstract

Inflammatory arthritis, hypoxia and vascularity

PC Taylor, A Steuer, P Etherington, D Cosgrove, RN Maini

Meeting abstract

Effects of cartilage-derived morphogenetic proteins and osteogenic protein-1 on osteochondrogenic differentiation of periosteum-derived cells

R Gruber, C Mayer, K Bobacz, M-T Krauth, W Graninger, FP Luyten, L Erlacher

Meeting abstract

Association between TNF -308A and systemic lupus erythematosus in relation to HLA-DR3 and six microsatellite markers on the short arm of chromosome VI

MW van der Linden, A van der Slik, E Pieterman, E Zanelli, MJ Giphart, FC Breedveld, RGJ Westendorp, TWJ Huizinga

Meeting abstract

A single nucleotide polymorphism on the IL-10 locus defines an expression polymorphism and a possible risk factor to develop RA

LR Lard, JJM Schonkeren, E Pieterman, R Westendorp, FC Breedveld, TWJ Huizinga

Meeting abstract

Elevated levels of soluble intercellular adhesion molecule -1 in systemic lupus erythematosus

N Kljukvina, S Shekshina, E Alexandrova, A Novicov, E Nassonov

Meeting abstract

T lymphocytes of patients with SLE lack Stat4

M Aringer, GH Stummvoll, G Steiner, CW Steiner, I Radda, JS Smolen, WB Graninger

Meeting abstract

Redox-sensitive changes in conformation and cellular localization of LAT and downstream TCR signaling lead to hyporesponsiveness of synovial fluid T cells in rheumatoid arthritis

SI Gringhuis, PHJ Remans, EAM Papendrecht-van der Voort, A Leow, EWN Levarht, FC Breedveld, CL Verweij

Meeting abstract

Defective Rap1 activation in synovial fluid T cells from patients with rheumatoid arthritis

PHJ Remans, SI Gringhuis, K Reedquist, FC Breedveld, JM van Laar, CL Verweij

Meeting abstract

The RIIbeta-subunit of protein kinase A (PKA) inhibits c-fos synthesis in T cells

N Mishra, M Tolnay, MR Elliott, DR Brown, GC Tsokos, GM Kammer

Meeting abstract

Invasion of synoviocytes is inhibited by gene transfer of TNF-BP or IL10 in an in vitro invasion model

E Pieterman, PH Goossens, WH van der Laan, AL Huidekoper, MJM Rabelink, RC Hoeben, JH Verheijen, FC Breedveld, TWJ Huizinga

Meeting abstract

Specific suppression of the transcription factor AP-1 by mepacrine

KM Stuhlmeier, C Linnert, H Bröll

Meeting abstract

Patterns of differentially expressed genes in synovial tissue from RA and OA patients and from normal joints

U Ungethüm, T Häupl, J Zacher, A Gursche, Förster, P Reutermann, A Pruβ, V Krenn, G-R Burmester

Meeting abstract

MMP-1, MMP-3 and MMP-10 are involved in the degradation of cartilage

TCA Tolboom, E Pieterman, WH van der Laan, AL Huidekoper, RGHH Nelissen, FC Breedveld, TWJ Huizinga

Meeting abstract

Enrichment of CD8+ CD28- cytotoxic T cells in circulating lymphocytes of patients with ankylosing spondylitis

M Schirmer, C Goldberger, C Duftner, J Clausen, A Falkenbach

Meeting abstract

Differences in B cell regulation in DRB1 shared epitope positive and negative rheumatoid arthritis

U Wagner, M Pierer, S Kaltenhäuser, B Wilke, S Arnold, H Häntzschel

Meeting abstract

p205 induces the production of rheumatoid factors

F Schumann, U Ungethüm, S Adelt, H Hofseß, A Gursche, J Zacher, JB Natvig, J-M Engel, G-R Burmester, S Bläß

Meeting abstract

Responses of the rat immune system to arthritogenic adjuvant-oil

L Svelander, BC Holm, A Bucht, JC Lorentzen

Meeting abstract

Characterization of autoreactive T cells to the autoantigens hnRNP-A2/RA33 and filaggrin in patients with rheumatoid arthritis and controls

R Fritsch, D Eselböck, B Jahn-Schmid, C Scheinecker, B Bohle, K Skriner, J Neumüller, J Smolen, G Steiner

Meeting abstract

Leflunomide leads to inhibition of transendothelial migration

J Grisar, GH Stummvoll, JS Smolen

Meeting abstract

Persistence of plasma cells in the kidneys of autoimmune NZB/W mice

G Cassese, S Lindenau, B de Boer, S Arce, A Hauser, G Riemekasten, C Berek, F Hiepe, A Radbruch, RA Manz

Meeting abstract

In vivo preactivated autoreactive Th cells in healthy individuals

A Radbruch, S Nitsch, B Holzknecht, E Gromnica-Ihle, S Schneider, F Hiepe, A Thiel

Meeting abstract

Characterization of RA33 (hnRNP-A2/B1)-autoreactive T cells in SLE-patients

R Fritsch, D Eselböck, B Jahn-Schmid, J Neumueller, B Bohle, K Skriner, J Smolen, G Steiner

Meeting abstract

Signalling via T cell receptor (TCR) in patients with SLE

M Cebecauer, L Cebecauer, D Kozáková, J Rovenský, J Lukáè, J Bartùòková

Meeting abstract

Impaired T-cell rsponse to subsequent TCR-stimulation after anti-CD3 induced proliferation

MD Köller, HP Kiener, M Aringer, W Graninger, Y Samstag, S Meuer, JS Smolen

Meeting abstract

Enhanced transendothelial in vitro migration of scleroderma lymphocytes

GH Stummvoll, M Aringer, J Grisar, CW Steiner, JS Smolen, R Knobler, WB Graninger

Meeting abstract

Autologous dendritic cells stimulate human HSP60 responsive T cells, in the absence of additional exogenous antigen

MS Lillicrap, MK Matyszak, JC Goodall, JL Young, JSH Gaston

Meeting abstract

Macrophages expressing the scavenger receptor CD163: a link between immune alterations of the gut and synovial inflammation in spondyloarthropathy

D Baeten, P Demetter, C Cuvelier, E Kruithof, N Van Damme, M De Vos, EM Veys, F De Keyser

Meeting abstract

Fully competent dendritic cells as inducers of T cell anergy in autoimmunity

S Quaratino, LP Duddy, M Londei

Meeting abstract

Dendritic cell subsets in rheumatoid arthritis

K Summers, J O'Donnell, A Rothwell

Meeting abstract

Detection of anti-B/B' UsnRNP antibodies in connective tissue disease sera by Western immunoblot

A Ghirardello, A Doria, S Zampieri, D Villalta, F Vescovi, PF Gambari

Meeting abstract

Comparison of different methods for the detection of the fine specificity of anti-Ro/SSA response

I Cavazzana, F Franceschini, M Quinzanini, P Airò, A Brucato, R Cattaneo

Meeting abstract

Study of the anti-idiotypic resonse to anti-LA/SSB autoantibodies using complementary peptides to B- and T-cell epitopes of La/SSB

JG Routsias, E Touloupi, A Moulia, M Sakarellos-Daitsiotis, H Dotsika, C Sakarellos, HM Moutsopoulos, AG Tzioufas

Meeting abstract

Induction of immune responses in inbreed mice by immunizations with the complementary 289-308 La/SSB epitope

Å Dotsika, Ì Papamattheou, P Tsagozis, Å Êaragouni, C Sakarellos, Ì Sakarellos-Daitsiotis, J Routsias, HM Ìoutsopoulos, ÁG Ôzioufas

Meeting abstract

Structure and function of an autoantigen, alpha-enloase

S Moscato, F Bongiorni, F Pratesi, M Scavuzzo, S Bombardieri, P Migliorini

Meeting abstract

Dominance of hydrophobic reading frames in complementarity determining region 3 of variable heavy chain genes from a patient with untreated SLE

B Yazdani-Biuki, R Brezinschek, T Dörner, J Hermann, H Mitterhammer, G Tilz, U Demel, T Müller, S Eder, J Gretler, HP Brezinschek

Meeting abstract

Immuno-serological profile of Systemic Erythemic Lupus (SLE) patients with neuropsychiatric manifestations (NP)

L Stojanovich, V Mircetic, R Stojanovich, V Kostich, D Popovich

Meeting abstract

Impaired in vitro thrombin generation in β2-glycoprotein I null mice

Y Sheng, SW Reddel, H Herzog, YX Wang, T Brighton, MP France, SA Krilis

Meeting abstract

Improving an anti-beta2 GPI ELISA by reducing the influence of a blocking agent

A Ambrozic, B Bozic, M Hojnik, T Kveder

Meeting abstract

Heterogeneous behaviour of anti-beta2-glycoprotein I antibodies on different "high binding" microtiter plates

A Ambrozic, T Kveder, K Ichikawa, T Avcin, M Hojnik, B Bozic, T Koike

Meeting abstract

Antibodies to β2-glycoprotein I, prothrombin and antithrombin III as markers of the antiphospholipid syndrome severity

J Zabek, S Luft, T Reshetniak, Z Alekberowa, B Wojciechowska, W Karlik, V Nasonowa

Meeting abstract

Differences between active immunoinflammatory and postinfectious fibromyalgia (FM)

I Wittrup, M Christiansen, B Jensen, H Bliddal, B Danneskiold-Samsøe, A Wiik

Meeting abstract

Disorders of the system of hemostasis and biochemical parameters of NZB/NZW F1 mice

AV Arshinov, OA Nazarova, GN Pleskovskaya, VV Redko

Meeting abstract

Adenoviral gene transfer of tissue inhibitors of metalloproteinases (TIMPs) reduces the invasive behaviour of rheumatoid fibroblast-like synovicytes

WH Van der Laan, L Huisman, E Pieterman, PHA Quax, JM TeKoppele, FC Breedveld, JH Verheijen, TWJ Huizinga

Meeting abstract

Adenoviral-based overexpression of TIMP-1 reduces tissue damage in the joints TNF-transgenic mice

G Schett, S Hayer, Q Xu, M Tohidast-Akrad, G Kollias, G Steiner, J Smolen

Meeting abstract

Altered migratory capacity of polymorphonuclear leucocytes as an effect of TNF-alpha blockade in patients with rheumatoid arthritis

H Mitterhammer, J Hermann, G Tilz, R Brezinschek, U Demel, B Yazdani-Biuki, T Müller, J Gretler, S Eder, HP Brezinschek

Meeting abstract

Development of a doxycycline inducible AAV vector for long term in vivo viral IL-10 gene transfer in rheumatoid arthritis

F Apparailly, D Noël, V Millet, C Jacquet, J Sany, C Jorgensen

Meeting abstract

IL-18 blockade is a potential disease-modifying therapy for rheumatoid arthritis

C Plater-Zyberk, LAB Joosten, MMA Helsen, P Sattonnet-Roche, C Siegfried, S Alouani, FAJ van de Loo, P Graber, S Aloni, CA Dinarello, WB van den Berg, Y Chvatchko

Meeting abstract

Digital vasculitis in a patient with rheumatoid arthritis: good response on anti-TNF blockade

F van den Hoogen, A den Broeder, M Zandbelt, L van de Putte

Meeting abstract

Effect of osteoprotegerin and pamidronate treatment in transgenic mice overexpressing human TNF

K Redlich, A Maier, S Hayer, G Kollias, CR Dunstan, M Tohidast-Akrad, S Lang, W Woloszczuk, G Steiner, JS Smolen, G Schett

Meeting abstract

Induction of a rapid progessive cartilage destruction in SCID mice by intraarticular application of a murine fibroblast like cell line

U Sack, A Hirth, B Funke, K Wiedemeyer, S Konrad, J Lehmann, F Emmrich

Meeting abstract

Infiltrate analysis of rheumatoid synovial tissue before and after high does chemotherapy and autologous stem cell transplantation

RJ Verburg, R Flierman, EWN Levahrt, F van den Hoogen, FC Breedveld, JM van Laar

Meeting abstract

Newer immunmodulating drugs in rheumatoid arthritis may precipitate glomerulonephritis

H Nielsen, E Kemp, LJ Petersen, AN Gam, J Dahlager, T Horn, S Larsen, S Olsen

Meeting abstract

Thymosin beta4 sylphoxide: potential role in resolution of inflammation?

JD Young, JA Gracie, RD Stevenson, AJ Lawrence, FY Liew, IB McInnes

Meeting abstract

New antirheumatic effects of biphosphonate treatment

L Konenkova, E Zonova, A Sizikov, M Korolev, S Tsareva, V Kozlov

Meeting abstract

Follow-up study of the effect of a three-month course of ciprofloxacin on the late prognosis of reactive arthritis

T Yli-Kerttula, R Luukkainen, U Yli-Kerttula, T Möttönen, M Hakola, M Korpela, M Sanila, A Toivanen

Meeting abstract

Early treatment of recent-onset rheumatoid arthritis patients impairs the effect of HLA class II antigents on the progression of joint destruction

LR Lard, JMW Hazes, FC Breedveld, GMTh Schreuder, RRP de Vries, E Zanelli, TWJ Huizinga

Meeting abstract

The shared epitope revisited: shared epitope negative HLA-DR alleles influence susceptibility to rheumatoid arthritis

D Reviron, A Perdriger, E Toussirot, D Wendling, N Balandraud, S Guis, G Semana, P Tiberghien, P Mercier, J Roudier

Meeting abstract

Positivity of HLA-DRB1 rheumatoid epitope does not predict the course of juvenile idiopathic arthritis in Czech children

O Cinek, P Vavrincová, P Drevínek, M Suková, S Rádová, J Vavrinec

Meeting abstract

In Marseille, Southern France, HLA-B2702 carries higher risk than HLA-B2705 to develop ankylosing spondylitis (AS)

S Guis, W Nielsen, G Boetsch, O Dutour, P Mercier, D Reviron, J Roudier

Meeting abstract

Juvenile idiopathic arthritis is associated to a functionally active polymorphism in the SH2D2A gene

A Smerdel, K-Z Dai, B Flato, R Ploski, O Forre, A Spurkland

Meeting abstract

Analysis of VH and VL mRNA in single synovial and peripheral B/plasma cells of patients with rheumatoid arthritis

S Ruzickova, J Vencovsky, O Krystufkova, Z Cimburek, J Sinkora, O Horvath, T Doerner

Meeting abstract

Disparate associations of the FcgammaRIIIa 158/V variant with RA in two diverse populations

A Milicic, R Misra, MA Brown, BP Wordsworth

Meeting abstract

Time to lupus nephritis: impact of gender and ethnicity

VA Seligman, H Li, JL Olson, LA Criswell

Meeting abstract

Increased apoptosis level in late stages of rheumatoid arthritis correlates with macrophage number

AI Catrina, A-K Ulfgren, L Gröndal, S Lindblad, L Klareskog

Meeting abstract

Nucleosome binding by serum amyloid P component from SLE patients

NHH Heegaard, L Rahbek, C Recke

Meeting abstract

Diagnostic value of synovial fluid analysis in pigmented villonodular synovitis (PVS)- a proposal of diagnostic criteria

I Zimmermann-Górska, M Puszczewicz, G Bialkowska-Puszczewicz

Meeting abstract

Analysis of anti-Ro52 antibodies in sera of healthy subjects

C Zimmermann, G Fabini, E Höfler, JS Smolen, G Steiner

Meeting abstract

Interphase fluorescence in situ hybridization analysis of fibroblast-like synoviocytes of patients with rheumatoid arthritis and osteoarthritis

HP Kiener, J Ackermann, K Redlich, I Radda, CW Steiner, P Bitzan, JS Smolen, J Drach

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