Ausgabe 2/2012
Inhalt (68 Artikel)
Plasma proteins take their toll on the joint in osteoarthritis
Steven R Goldring, Carla R Scanzello
Implication of new atherosclerotic carotid plaques in the cardiovascular outcome of patients with rheumatoid arthritis
Miguel A González-Gay, Carlos González-Juanatey
The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis
Raquel López-Mejías, Carlos González-Juanatey, Mercedes García-Bermúdez, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Javier Llorca, Javier Martín, Miguel A González-Gay
Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes
Chiyoko Sekine, Akemi Koyanagi, Noriko Koyama, Katsuto Hozumi, Shigeru Chiba, Hideo Yagita
Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis
Marie Hudson, Janet Pope, Michael Mahler, Solène Tatibouet, Russell Steele, Murray Baron, Marvin J Fritzler
Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage
Girish Ramaswamy, Philip Sohn, Alan Eberhardt, Rosa Serra
Is IL-6 an appropriate target to treat spondyloarthritis patients refractory to anti-TNF therapy? a multicentre retrospective observational study
Fernando Kemta Lekpa, Cécile Poulain, Daniel Wendling, Martin Soubrier, Michel De Bandt, Jean Marie Berthelot, Philippe Gaudin, Eric Toussirot, Philippe Goupille, Thao Pham, Jérémie Sellam, Rémy Bruckert, Muriel Paul, Valérie Farrenq, Pascal Claudepierre
The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression
Daniela Frölich, Daniela Blaβfeld, Karin Reiter, Claudia Giesecke, Capucine Daridon, Henrik E Mei, Gerd R Burmester, David M Goldenberg, Abdulagabar Salama, Thomas Dörner
TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome
Seung-Ki Kwok, Mi-La Cho, Yang-Mi Her, Hye-Joa Oh, Mi-Kyung Park, Seon-Yeong Lee, Yun Ju Woo, Ji Hyeon Ju, Kyung-Su Park, Ho-Youn Kim, Sung-Hwan Park
Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study
Evangelia Zampeli, Athanase Protogerou, Kimon Stamatelopoulos, Kalliopi Fragiadaki, Christina G Katsiari, Katerina Kyrkou, Christos M Papamichael, Myron Mavrikakis, Peter Nightingale, George D Kitas, Petros P Sfikakis
Moving instead of asking? Performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis
Salima FE van Weely, J Christiaan van Denderen, Martijn PM Steultjens, Marike van der Leeden, Michael T Nurmohamed, Joost Dekker, Ben AC Dijkmans, Irene E van der Horst-Bruinsma
Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis
Kirsten Braem, Christophe M Deroose, Frank P Luyten, Rik J Lories
Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators?
Joseph Paquet, Jean-Christophe Goebel, Camille Delaunay, Astrid Pinzano, Laurent Grossin, Christel Cournil-Henrionnet, Pierre Gillet, Patrick Netter, Jean-Yves Jouzeau, David Moulin
What is the future of CCR5 antagonists in rheumatoid arthritis?
Tsutomu Takeuchi, Hideto Kameda
Clinical features of symptomatic patellofemoral joint osteoarthritis
George Peat, Rachel C Duncan, Laurence RJ Wood, Elaine Thomas, Sara Muller
A systematic critical review on MRI in spondyloarthritis
Bodil Arnbak, Charlotte Leboeuf-Yde, Tue Secher Jensen
Characterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate
Cécile Lambert, Marianne Mathy-Hartert, Jean-Emile Dubuc, Eulàlia Montell, Josep Vergés, Carine Munaut, Agnès Noël, Yves Henrotin
Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis
Altan Ercan, Jing Cui, Melissa M Hazen, Franak Batliwalla, Louise Royle, Pauline M Rudd, Jonathan S Coblyn, Nancy Shadick, Michael E Weinblatt, Peter Gregersen, David M Lee, Peter A Nigrovic
Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration
Takashi Yurube, Toru Takada, Teppei Suzuki, Kenichiro Kakutani, Koichiro Maeno, Minoru Doita, Masahiro Kurosaka, Kotaro Nishida
Effect of pregnancy on serum cytokines in SLE patients
Andrea Doria, Maurizio Cutolo, Anna Ghirardello, Margherita Zen, Danilo Villalta, Angela Tincani, Leonardo Punzi, Luca Iaccarino, Michelle Petri
Sustained rheumatoid arthritis remission is uncommon in clinical practice
Femke HM Prince, Vivian P Bykerk, Nancy A Shadick, Bing Lu, Jing Cui, Michelle Frits, Christine K Iannaccone, Michael E Weinblatt, Daniel H Solomon
Dutch translation and cross-cultural adaptation of the PROMIS® physical function item bank and cognitive pre-test in Dutch arthritis patients
Martijn AH Oude Voshaar, Peter M ten Klooster, Erik Taal, Eswar Krishnan, Mart AFJ van de Laar
Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity
Fumihito Suzuki, Tetsuo Kubota, Yasunari Miyazaki, Kinya Ishikawa, Masashi Ebisawa, Shunsei Hirohata, Takashi Ogura, Hidehiro Mizusawa, Toshio Imai, Nobuyuki Miyasaka, Toshihiro Nanki
Knotting the NETs: Analyzing histone modifications in neutrophil extracellular traps
Indira Neeli, Marko Radic
Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes
Sarah-Salwa Nebbaki, Fatima Ezzahra El Mansouri, Hassan Afif, Mohit Kapoor, Mohamed Benderdour, Nicolas Duval, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Hassan Fahmi
Erratum to: FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development
Rizwanul Haque, Fengyang Lei, Xiaofang Xiong, Yuzhang Wu, Jianxun Song
The independent association between parathyroid hormone levels and hyperuricemia: a national population study
Janet Y Hui, Jee Woong J Choi, David B Mount, Yanyan Zhu, Yuqing Zhang, Hyon K Choi
Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity
YK Onno Teng, Gillian Wheater, Vanessa E Hogan, Philip Stocks, EW Nivine Levarht, Tom WJ Huizinga, Rene EM Toes, Jacob M van Laar
MRI and X-ray in axial spondyloarthritis: the relationship between inflammatory and structural changes
Walter P Maksymowych
Congenital heart block: evidence for a pathogenic role of maternal autoantibodies
Aurélie Ambrosi, Marie Wahren-Herlenius
Role of non-immune mechanisms of muscle damage in idiopathic inflammatory myopathies
William Coley, Sree Rayavarapu, Kanneboyina Nagaraju
TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts
Alison M Connor, Nizar Mahomed, Rajiv Gandhi, Edward C Keystone, Stuart A Berger
Induction of superficial zone protein (SZP)/lubricin/PRG 4 in muscle-derived mesenchymal stem/progenitor cells by transforming growth factor-β1 and bone morphogenetic protein-7
José A Andrades, Shirley C Motaung, Pedro Jiménez-Palomo, Silvia Claros, José M López-Puerta, José Becerra, Thomas M Schmid, A Hari Reddi
Replication study confirms the association between UBAC2 and Behçet's disease in two independent Chinese sets of patients and controls
Shengping Hou, Qinmeng Shu, Zhengxuan Jiang, Yuanyuan Chen, Fuzhen Li, Feilan Chen, Aize Kijlstra, Peizeng Yang
Increased frequency of CCR4+ and CCR6+ memory T-cells including CCR7+CD45RAmed very early memory cells in granulomatosis with polyangiitis (Wegener's)
Ursula Fagin, Silke Pitann, Wolfgang L Gross, Peter Lamprecht
Progress in treatment of ANCA-associated vasculitis
Rona M Smith, Rachel B Jones, David RW Jayne
Bone formation rather than inflammation reflects Ankylosing Spondylitis activity on PET-CT: a pilot study
Stefan TG Bruijnen, Mignon AC van der Weijden, Joannes P Klein, Otto S Hoekstra, Ronald Boellaard, J Christiaan van Denderen, Ben AC Dijkmans, Alexandre E Voskuyl, Irene E van der Horst-Bruinsma, Conny J van der Laken
Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis
Carmen A Ambarus, Troy Noordenbos, Maria JH de Hair, Paul P Tak, Dominique LP Baeten
miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4
Jing Li, Jingang Huang, Liming Dai, Degang Yu, Qian Chen, Xiaoling Zhang, Kerong Dai
Estradiol ameliorates arthritis and protects against systemic bone loss in Staphylococcus aureus infection in mice
Inger Gjertsson, Marie K Lagerquist, Erik Kristiansson, Hans Carlsten, Catharina Lindholm
Circulating and synovial antibody profiling of juvenile arthritis patients by nucleic acid programmable protein arrays
David S Gibson, Ji Qiu, Eliseo A Mendoza, Kristi Barker, Madeleine E Rooney, Joshua LaBaer
Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study
Ying Chen, Peter T Dawes, Jon C Packham, Derek L Mattey
Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance
Kazuhiro Kiyama, Daisuke Kawabata, Yuji Hosono, Koji Kitagori, Naoichiro Yukawa, Hajime Yoshifuji, Koichiro Omura, Takao Fujii, Tsuneyo Mimori
Functional role of IL-22 in psoriatic arthritis
Anupam Mitra, Smriti K Raychaudhuri, Siba P Raychaudhuri
Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis
Kyle D Allen, Brian A Mata, Mostafa A Gabr, Janet L Huebner, Samuel B Adams Jr, Virginia B Kraus, Daniel O Schmitt, Lori A Setton
Risk of end-stage renal disease associated with gout: a nationwide population study
Kuang-Hui Yu, Chang-Fu Kuo, Shue-Fen Luo, Lai-Chu See, I-Jun Chou, Hsiao-Chun Chang, Meng-Jiun Chiou
Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization
Beate Böhm, Harald Burkhardt, Steffen Uebe, Maria Apel, Frank Behrens, André Reis, Ulrike Hüffmeier
Autoantibodies to transcription intermediary factor (TIF)1β associated with dermatomyositis
Minoru Satoh, Jason YF Chan, Steven J Ross, Yi Li, Yoshioki Yamasaki, Hidehiro Yamada, Monica Vazquez-del Mercado, Marcelo H Petri, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Reyes, Eric S Sobel, Westley H Reeves, Angela Ceribelli, Edward KL Chan
Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus
Shui-Lian Yu, Paul KS Chan, Chun-Kwok Wong, Cheuk-Chun Szeto, Suzanne C Ho, Karine So, May MY Yu, So-Fan Yim, Tak-Hong Cheung, Martin CS Wong, Jo LK Cheung, Apple CM Yeung, Edmund K Li, Lai-Shan Tam
A multicenter study confirms CD226gene association with systemic sclerosis-related pulmonary fibrosis
Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper C Broen, Madelon C Vonk, Raquel Ríos-Fernández, Gerard Espinosa, Patricia Carreira, María T Camps, Maria J Castillo, Miguel A González-Gay, Emma Beltrán, María del Carmen Freire, Javier Narváez, Carlos Tolosa, Torsten Witte, Alexander Kreuter, Annemie J Schuerwegh, Anna-Maria Hoffmann-Vold, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Meng May Chee, Ariane Herrick, Bobby PC Koeleman, Christopher P Denton, Carmen Fonseca, Timothy RDJ Radstake, Javier Martin
Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: a cross-sectional study
Ahmed Solomon, Gavin R Norton, Angela J Woodiwiss, Patrick H Dessein
The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes
Kenji Ikuta, Yuko Waguri-Nagaya, Kae Kikuchi, Takaya Yamagami, Masahiro Nozaki, Mineyoshi Aoyama, Kiyofumi Asai, Takanobu Otsuka
Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA)
Chun Lai Too, Abqariyah Yahya, Shahnaz Murad, Jasbir Singh Dhaliwal, Per Tobias Larsson, Nor Asiah Muhamad, Nor Aini Abdullah, Amal Nasir Mustafa, Lars Klareskog, Lars Alfredsson, Leonid Padyukov, Camilla Bengtsson
Statins accelerate the onset of collagen type II-induced arthritis in mice
Rob J Vandebriel, Hilda JI De Jong, Eric R Gremmer, Olaf H Klungel, Jan-Willem Cohen Tervaert, Wout Slob, Jan Willem Van Der Laan, Henk Van Loveren
Thrombin induces heme oxygenase-1 expression in human synovial fibroblasts through protease-activated receptor signaling pathways
Ju-Fang Liu, Sheng-Mou Hou, Chun-Hao Tsai, Chun-Yin Huang, Wei-Hung Yang, Chih-Hsin Tang
The renal urate transporter SLC17A1 locus: confirmation of association with gout
Jade E Hollis-Moffatt, Amanda J Phipps-Green, Brett Chapman, Gregory T Jones, Andre van Rij, Peter J Gow, Andrew A Harrison, John Highton, Peter B Jones, Grant W Montgomery, Lisa K Stamp, Nicola Dalbeth, Tony R Merriman
Synovial cytokine expression in psoriatic arthritis and associations with lymphoid neogenesis and clinical features
Raquel Celis, Núria Planell, José L Fernández-Sueiro, Raimon Sanmartí, Julio Ramírez, Isidoro González-Álvaro, José L Pablos, Juan D Cañete
Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study
Elisa Alonso-Perez, Marian Suarez-Gestal, Manuel Calaza, Gian Domenico Sebastiani, Rudolf Pullmann, Chryssa Papasteriades, Attila Kovacs, Fotini N Skopouli, Marc Bijl, Ana Suarez, Maurizio Marchini, Sergio Migliaresi, Patricia Carreira, Josep Ordi-Ros, Torsten Witte, Sarka Ruzickova, Maria Jose Santos, Nadia Barizzone, Francisco J Blanco, Bernard R Lauwerys, Juan J Gomez-Reino, Antonio Gonzalez
Interleukin-6 regulates anti-arthritic effect of methotrexate via reduction of SLC19A1 expression in a mouse arthritis model
Misato Hashizume, Hiroto Yoshida, Keisuke Tanaka, Miho Suzuki, Isao Matsumoto, Takayuki Sumida, Masahiko Mihara
Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes
Ioanna Papathanasiou, Konstantinos N Malizos, Aspasia Tsezou
The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study
Suzanne Arends, Anneke Spoorenberg, Pieternella M Houtman, Martha K Leijsma, Reinhard Bos, Cees GM Kallenberg, Henk Groen, Elisabeth Brouwer, Eveline van der Veer
Anti-MJ/NXP-2 autoantibody specificity in a cohort of adult Italian patients with polymyositis/dermatomyositis
Angela Ceribelli, Micaela Fredi, Mara Taraborelli, Ilaria Cavazzana, Franco Franceschini, Marzia Quinzanini, Angela Tincani, Steven J Ross, Jason YF Chan, Brad A Pauley, Edward KL Chan, Minoru Satoh
Suppression of endothelial cell activity by inhibition of TNFα
Qiang Shu, Mohammad A Amin, Jeffrey H Ruth, Phillip L Campbell, Alisa E Koch
The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients
Hennie G Raterman, Saskia Vosslamber, Sander de Ridder, Michael T Nurmohamed, Willem F Lems, Maarten Boers, Mark van de Wiel, Ben AC Dijkmans, Cornelis L Verweij, Alexandre E Voskuyl
Value of self-performed joint counts in rheumatoid arthritis patients near remission
Helga Radner, Johannes Grisar, Josef S Smolen, Tanja Stamm, Daniel Aletaha
Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study
Johanna T Gustafsson, Julia F Simard, Iva Gunnarsson, Kerstin Elvin, Ingrid E Lundberg, Lars-Olof Hansson, Anders Larsson, Elisabet Svenungsson