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Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 6/2014

01.06.2014 | Ankle

Arthroscopic autologous chondrocyte implantation in the ankle joint

verfasst von: Sandro Giannini, Roberto Buda, Alberto Ruffilli, Marco Cavallo, Gherardo Pagliazzi, Maria Chiara Bulzamini, Giovanna Desando, Deianira Luciani, Francesca Vannini

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 6/2014

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Abstract

Purpose

Autologous chondrocyte implantation (ACI) is an established procedure in the ankle providing satisfactory results. The development of a completely arthroscopic ACI procedure in the ankle joint made the technique easier and reduced the morbidity. The purpose of this investigation was to report the clinical results of a series of patients who underwent arthroscopic ACI of the talus at a mean of 7 ± 1.2-year follow-up.

Methods

Forty-six patients (mean age 31.4 ± 7.6) affected by osteochondral lesions of the talar dome (OLT) received arthroscopic ACI between 2001 and 2006. Patients were clinically evaluated using AOFAS score pre-operatively and at 12, 36 months and at final follow-up of 87.2 ± 14.5 months.

Results

The mean pre-operative AOFAS score was 57.2 ± 14.3. At the 12-month follow-up, the mean AOFAS score was 86.8 ± 13.4 (p = 0.0005); at 36 months after surgery, the mean score was 89.5 ± 13.4 (p = 0.0005); whereas at final follow-up of 87.2 ± 14.5 months it was 92.0 ± 11.2 (p = 0.0005). There were three failures. Histological and immunohistochemical evaluations of specimens harvested from failed implants generally showed several aspects of a fibro-cartilaginous tissue associated with some aspects of cartilage tissue remodelling as indicated by the presence of type II collagen expression.

Conclusion

This study confirmed the ability of arthroscopic ACI to repair osteochondral lesions in the ankle joint with satisfactory clinical results after mid-term follow-up.

Level of evidence

IV, retrospective case series.
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Metadaten
Titel
Arthroscopic autologous chondrocyte implantation in the ankle joint
verfasst von
Sandro Giannini
Roberto Buda
Alberto Ruffilli
Marco Cavallo
Gherardo Pagliazzi
Maria Chiara Bulzamini
Giovanna Desando
Deianira Luciani
Francesca Vannini
Publikationsdatum
01.06.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 6/2014
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-013-2640-7

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