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Erschienen in: Journal of Artificial Organs 1/2018

21.09.2017 | Review

Artificial sensory organs: latest progress

verfasst von: Tatsuo Nakamura, Yuji Inada, Keiji Shigeno

Erschienen in: Journal of Artificial Organs | Ausgabe 1/2018

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Abstract

This study introduces the latest progress on the study of artificial sensory organs, with a special emphasis on the clinical results of artificial nerves and the concept of in situ tissue engineering. Peripheral nerves have a strong potential for regeneration. An artificial nerve uses this potential to recover a damaged peripheral nerve. The polyglycolic acid collagen tube (PGA-C tube) is a bio-absorbable tube stuffed with collagen of multi-chamber structure that consists of thin collagen films. The clinical application of the PGA-C tube began in 2002 in Japan. The number of PGA-C tubes used is now beyond 300, and satisfactory results have been reported on peripheral nerve repairs. This PGA-C tube is also effective for patients suffering from neuropathic pain.
Literatur
1.
Zurück zum Zitat Nishimura Y. Restoring voluntary limb control via an artificial neural connection to spinal circuits. J Clin Exp Med (Igaku no Ayumi). 2013;246:582–7. Nishimura Y. Restoring voluntary limb control via an artificial neural connection to spinal circuits. J Clin Exp Med (Igaku no Ayumi). 2013;246:582–7.
2.
Zurück zum Zitat Kanda H, Fujikado T. Artificial organs on sensory system-artificial retina. Jinko Zoki (Jpn Soc Artif Organs). 2012;41:202–6. Kanda H, Fujikado T. Artificial organs on sensory system-artificial retina. Jinko Zoki (Jpn Soc Artif Organs). 2012;41:202–6.
3.
Zurück zum Zitat Kumakawa K. Artificial sensory organ for severe hearing loss. Jinko Zoki (Jpn Soc Artif Organs). 2011;40:189–93. Kumakawa K. Artificial sensory organ for severe hearing loss. Jinko Zoki (Jpn Soc Artif Organs). 2011;40:189–93.
4.
Zurück zum Zitat Matsumoto N. Conditions and outlook for cochlear. Jinko Zoki (Jpn Soc Artif Organs). 2013;42:10–3. Matsumoto N. Conditions and outlook for cochlear. Jinko Zoki (Jpn Soc Artif Organs). 2013;42:10–3.
5.
Zurück zum Zitat Kojima K, Ignotz RA, Kushibiki T, Tinsley KW, Tabata Y, Vacanti CA. Tissue-engineered trachea from sheep marrow stromal cells with transforming growth factor β2 released from biodegradable microspheres in a nude rat recipient. J Thorac Cardiovasc Surg. 2004;128:147–53.CrossRefPubMed Kojima K, Ignotz RA, Kushibiki T, Tinsley KW, Tabata Y, Vacanti CA. Tissue-engineered trachea from sheep marrow stromal cells with transforming growth factor β2 released from biodegradable microspheres in a nude rat recipient. J Thorac Cardiovasc Surg. 2004;128:147–53.CrossRefPubMed
6.
Zurück zum Zitat Hori Y, Nakamura T, Matsumoto K, Kurokawa Y, Satomi S, Shimizu Y. Experimental study on in situ tissue engineering of the stomach by an acellular collagen sponge scaffold graft. ASAIO J. 2001;47:206–10.CrossRefPubMed Hori Y, Nakamura T, Matsumoto K, Kurokawa Y, Satomi S, Shimizu Y. Experimental study on in situ tissue engineering of the stomach by an acellular collagen sponge scaffold graft. ASAIO J. 2001;47:206–10.CrossRefPubMed
7.
Zurück zum Zitat Allen Frances. Chapter 6: fads of the future. Saving normal. William Morrow, New York, 2013, p. p174. Allen Frances. Chapter 6: fads of the future. Saving normal. William Morrow, New York, 2013, p. p174.
8.
Zurück zum Zitat Dahlin LB, Lundborg G. Nerve repair: experimental and clinical update. In: Tubiana R, Gilbert A, editors. Tendon, nerve and other disorders (surgery of disorders of the hand and upper extremity). London: Taylor & Francis; 2005. p. 95–104. Dahlin LB, Lundborg G. Nerve repair: experimental and clinical update. In: Tubiana R, Gilbert A, editors. Tendon, nerve and other disorders (surgery of disorders of the hand and upper extremity). London: Taylor & Francis; 2005. p. 95–104.
9.
Zurück zum Zitat Weber RA, Breidenbach WC, Brown RE, Jabaley ME, Mass DP. A randomized prospective study of polyglycolic acid conduits for digital nerve reconstruction in humans. Plast Reconstr Surg. 2000;106:1036–45.CrossRefPubMed Weber RA, Breidenbach WC, Brown RE, Jabaley ME, Mass DP. A randomized prospective study of polyglycolic acid conduits for digital nerve reconstruction in humans. Plast Reconstr Surg. 2000;106:1036–45.CrossRefPubMed
10.
Zurück zum Zitat Kehoe S, Zhang XF, Boyd D. FDA approved guidance conduits and wraps for peripheral nerve injury: a review of materials and efficacy. Injury. 2012;43:553–72.CrossRefPubMed Kehoe S, Zhang XF, Boyd D. FDA approved guidance conduits and wraps for peripheral nerve injury: a review of materials and efficacy. Injury. 2012;43:553–72.CrossRefPubMed
11.
Zurück zum Zitat Uemura T, Takamatsu K, et al. The combination of iPS cell technology and bioabsorbable nerve conduit for the treatment of peripheral nerve defects. Pharma Medica. 2013;31:37–42. Uemura T, Takamatsu K, et al. The combination of iPS cell technology and bioabsorbable nerve conduit for the treatment of peripheral nerve defects. Pharma Medica. 2013;31:37–42.
12.
Zurück zum Zitat Toba T, Nakamura T, Shimizu Y, Matsumoto K, Ohnishi K, Fukuda S, Endo K. Regeneration of canine peroneal nerve with the use of a polyglycolic acid-collagen tube filled with laminin-soaked collagen sponge: a comparative study of collagen sponge and collagen fibers as filling materials for nerve conduits. J Biomed Mater Res. 2001;58:622–30.CrossRefPubMed Toba T, Nakamura T, Shimizu Y, Matsumoto K, Ohnishi K, Fukuda S, Endo K. Regeneration of canine peroneal nerve with the use of a polyglycolic acid-collagen tube filled with laminin-soaked collagen sponge: a comparative study of collagen sponge and collagen fibers as filling materials for nerve conduits. J Biomed Mater Res. 2001;58:622–30.CrossRefPubMed
13.
Zurück zum Zitat Matsumoto K, Ohnishi K, Kiyotani T, Sekine T, Ueda H, Nakamura T, Shimizu Y. Peripheral nerve regeneration across an 80-mm gap bridged by a polyglycolic acid (PGA)-collagen tube filled with laminin-coated collagen fibers: a histological and electrophysiological evaluation of regenerated nerves. Brain Res. 2000;868:315–28.CrossRefPubMed Matsumoto K, Ohnishi K, Kiyotani T, Sekine T, Ueda H, Nakamura T, Shimizu Y. Peripheral nerve regeneration across an 80-mm gap bridged by a polyglycolic acid (PGA)-collagen tube filled with laminin-coated collagen fibers: a histological and electrophysiological evaluation of regenerated nerves. Brain Res. 2000;868:315–28.CrossRefPubMed
14.
Zurück zum Zitat Nakamura T, Inada Y, Fukuda S, Yoshitani M, Nakada A, Itoi SI, Shimizu Y. Experimental study on the regeneration of peripheral nerve gaps through a polyglycolic acid-collagen (PGA-collagen) tube. Brain Res. 2004;1027:18–29.CrossRefPubMed Nakamura T, Inada Y, Fukuda S, Yoshitani M, Nakada A, Itoi SI, Shimizu Y. Experimental study on the regeneration of peripheral nerve gaps through a polyglycolic acid-collagen (PGA-collagen) tube. Brain Res. 2004;1027:18–29.CrossRefPubMed
15.
Zurück zum Zitat Hagiwara A, Yamagishi H, et al. Novel functional reconstruction of the resected nerve by surgery for a recurrent colon cancer. J Ther. 2002;84:158–9. Hagiwara A, Yamagishi H, et al. Novel functional reconstruction of the resected nerve by surgery for a recurrent colon cancer. J Ther. 2002;84:158–9.
16.
Zurück zum Zitat Seo K, Inada Y, Terumitsu M, Nakamura T, Horiuchi K, Inada I, Someya G. One year outcome of damaged lingual nerve repair using a PGA-collagen tube: a case report. J Oral Maxillofac Surg. 2008;66:1481–4.CrossRefPubMed Seo K, Inada Y, Terumitsu M, Nakamura T, Horiuchi K, Inada I, Someya G. One year outcome of damaged lingual nerve repair using a PGA-collagen tube: a case report. J Oral Maxillofac Surg. 2008;66:1481–4.CrossRefPubMed
17.
Zurück zum Zitat Seo K, Inada Y, Terumitsu M, Nakamura T, Shigeno K, Tanaka Y, Matsuzawa H. Protracted delay in taste sensation recovery after surgical lingual nerve repair: a case report. J Med Case Rep. 2013;7:77.CrossRefPubMedPubMedCentral Seo K, Inada Y, Terumitsu M, Nakamura T, Shigeno K, Tanaka Y, Matsuzawa H. Protracted delay in taste sensation recovery after surgical lingual nerve repair: a case report. J Med Case Rep. 2013;7:77.CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Kanemaru SI, Omori K, Hiratsuka Y, Kojima H, Ito J, Nakamura T, Shimizu Y. Recurrent laryngeal nerve regeneration by tissue engineering. Ann Otol Rhinol Laryngol. 2003;112:492–8.CrossRefPubMed Kanemaru SI, Omori K, Hiratsuka Y, Kojima H, Ito J, Nakamura T, Shimizu Y. Recurrent laryngeal nerve regeneration by tissue engineering. Ann Otol Rhinol Laryngol. 2003;112:492–8.CrossRefPubMed
21.
Zurück zum Zitat Inada Y, Morimoto S, Takakura Y, Nakamura T. Regeneration of peripheral nerve gaps with a polyglycolic acid-collagen tube. Neurosurgery. 2004;55:640–8.CrossRefPubMed Inada Y, Morimoto S, Takakura Y, Nakamura T. Regeneration of peripheral nerve gaps with a polyglycolic acid-collagen tube. Neurosurgery. 2004;55:640–8.CrossRefPubMed
22.
Zurück zum Zitat Inada Y, Morimoto S, Moroi K, Endo K, Nakamura T. Surgical relief of causalgia with an artificial nerve guide tube: successful surgical treatment of causalgia (complex regional pain syndrome type II) by in situ tissue engineering with a polyglycolic acid-collagen tube. Pain. 2005;117:251–8.CrossRefPubMed Inada Y, Morimoto S, Moroi K, Endo K, Nakamura T. Surgical relief of causalgia with an artificial nerve guide tube: successful surgical treatment of causalgia (complex regional pain syndrome type II) by in situ tissue engineering with a polyglycolic acid-collagen tube. Pain. 2005;117:251–8.CrossRefPubMed
Metadaten
Titel
Artificial sensory organs: latest progress
verfasst von
Tatsuo Nakamura
Yuji Inada
Keiji Shigeno
Publikationsdatum
21.09.2017
Verlag
Springer Japan
Erschienen in
Journal of Artificial Organs / Ausgabe 1/2018
Print ISSN: 1434-7229
Elektronische ISSN: 1619-0904
DOI
https://doi.org/10.1007/s10047-017-0990-5

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