17.06.2022 | ASO Author Reflections
ASO Author Reflections: Better Long-Term Survival in Esophageal Cancer After Minimally Invasive Versus Open Transthoracic Esophagectomy in Sweden: A Population-Based Cohort Study
verfasst von:
Masaru Hayami, MD, PhD, Nelson Ndegwa, MSc, Mats Lindblad, MD, PhD, Gustav Linder, MD, PhD, Jakob Hedberg, MD, PhD, David Edholm, MD, PhD, Jan Johansson, MD, PhD, Jesper Lagergren, MD, PhD, Lars Lundell, MD, PhD, Magnus Nilsson, MD, PhD, Ioannis Rouvelas, MD, PhD
Erschienen in:
Annals of Surgical Oncology
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Ausgabe 9/2022
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Excerpt
Minimally invasive esophagectomy (MIE) with a thoracoscopic and/or laparoscopic approach aimed at reducing the surgical trauma versus conventional open esophagectomy (OE) has recently gained popularity as a curatively intended treatment of esophageal cancer. According to randomized controlled trials (RCTs), totally minimally invasive esophagectomy (TMIE), a procedure combining thoracosopic and laparoscopic access, and hybrid MIE (HMIE), a procedure usually combining laparoscopic abdominal access with open thoracic access, both are associated with improved postoperative outcomes, especially a lower rate of pulmonary complications and better postoperative health-related quality of life (HRQOL) than OE.
1 In contrast, population-based cohort studies, reflecting clinical practice, report ambiguous short-term outcomes after MIE.
2,3 A recent meta-analysis of the existing literature indicated lower 5-year mortality after MIE than after OE (pooled hazard ratio, 0.82; 95 % confidence interval, 0.76–0.88), but highlighted a need for more population-based cohort studies.
4 …
