Erschienen in:
17.08.2020 | ASO Author Reflections
ASO Author Reflections: Multiple Ipsilateral Breast Cancer: Where Have We Been, Where are We Going
verfasst von:
Kari M. Rosenkranz, MD, Judy C. Boughey, MD
Erschienen in:
Annals of Surgical Oncology
|
Sonderheft 3/2020
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Excerpt
Surgeons have long demonstrated a bias toward mastectomy over breast-conservation treatment (BCT) for the surgical management of patients with multiple ipsilateral breast cancer (MIBC). This practice evolved from retrospective data reported in the 1970s and 1980s documenting a prohibitively high risk of local recurrence in women with MIBC treated with BCT. At the time these data were collected, tumors were largely more advanced (pre-screening mammography), margins were assessed poorly or not at all, and patients did not receive targeted therapies. As these practices improved, retrospective studies from the 1990s and 2000s began reporting lower local recurrence rates with BCT in patients with MIBC, more similar to those of women with unifocal disease.
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