Erschienen in:
12.11.2018 | ASO Author Reflections
ASO Author Reflections: Outcomes of Gastroesophageal Neuroendocrine Tumors
verfasst von:
Katherine D. Gray, MD, Rasa Zarnegar, MD
Erschienen in:
Annals of Surgical Oncology
|
Sonderheft 3/2018
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Excerpt
Gastroesophageal neuroendocrine tumors (GE-NETs) are rare tumors with a variable clinical course, and with the exception of indolent, gastrin-dependent type I and II NETs, epidemiologic patterns within these sites are largely undescribed. Poorly differentiated GE-NETs, in particular, are highly aggressive with known median survival of less than 1 year.
1 However, treatment algorithms rely on those for small cell lung cancer,
2 with only limited, mostly retrospective data evaluating treatment regimens specific for these patients.
3,4 Additionally, little is known regarding optimal surgical management of these often invasive and metastatic tumors. This study utilized the National Cancer Database, a combined endeavor of the American College of Surgeons and the American Cancer Society which provides a large cohort of these rare patients, to define risk factors for aggressive behavior and evaluate treatment strategies.
5 …
