Erschienen in:
04.04.2020 | ASO Author Reflections
ASO Author Reflections: Primary Site Should Be Regarded as One Important Factor for Risk Stratification in Acral Melanoma
Erschienen in:
Annals of Surgical Oncology
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Ausgabe 9/2020
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Excerpt
Acral melanoma is the least common subtype in Caucasian patients but constitutes up to 50–75% in population of color.
1 Compared with melanoma from other cutaneous lesions, acral melanoma is associated with worse survival outcome due to late diagnosis and negative clinical characteristics, including deeper Breslow thickness, more frequent ulceration, and higher clinical stage at diagnosis.
2,
3 Although acral melanoma is a distinctive subtype, notable variations exist within this population. Only limited studies with small sample size have focused on the differences of primary sites: soles, palms, and nail beds. On the whole, no agreement has been reached and results in present research are conflicting. …