Skip to main content
Erschienen in:

16.08.2024 | ASO Author Reflections

ASO Author Reflections: Prognostic Impact of Postoperative Oral Nutritional Supplements in Gastric Cancer

verfasst von: Takeshi Omori, MD, PhD, Kazuyoshi Yamamoto, MD, PhD, Yukinori Kurokawa, MD, PhD, Yasuhiro Miyazaki, MD, PhD, Kazumasa Fujitani, MD, PhD, Ryohei Kawabata, MD, PhD, Hiroshi Imamura, MD, PhD, Atsushi Takeno, MD, PhD, Yoshitomo Yanagimoto, MD, PhD, Tsuyoshi Takahashi, MD, PhD, Takuro Saito, MD, PhD, Hidetoshi Eguchi, MD, PhD, Yuichiro Doki, MD, PhD

Erschienen in: Annals of Surgical Oncology | Ausgabe 12/2024

Einloggen, um Zugang zu erhalten

Auszug

Weight loss (WL) after gastrectomy for gastric cancer has been reported to be associated with decreased compliance with adjuvant chemotherapy and worse prognosis.1 Although several surgical approaches have been tried to reduce WL, including procedures that avoid total gastrectomy as much as possible, as well as minimally invasive surgery, the issue of WL has not been resolved. Many gastrointestinal surgeons recognize the importance of preventing WL after gastrectomy, and several clinical trials have been conducted using oral nutritional supplements (ONSs) to reduce WL, but the efficacy has not been fully demonstrated. Furthermore, it is unclear how many calories or how much protein should be administered by ONS, how long the nutritional intervention should be continued, and how much nutritional improvement is required to improve clinical outcomes, especially long-term oncologic outcomes. …
Literatur
1.
Zurück zum Zitat Aoyama T, Kawabe T, Fujikawa H, et al. Loss of lean body mass as an independent risk factor for continuation of S-1 adjuvant chemotherapy for gastric cancer. Ann Surg Oncol. 2015;22(8):2560–6.CrossRefPubMed Aoyama T, Kawabe T, Fujikawa H, et al. Loss of lean body mass as an independent risk factor for continuation of S-1 adjuvant chemotherapy for gastric cancer. Ann Surg Oncol. 2015;22(8):2560–6.CrossRefPubMed
2.
Zurück zum Zitat Miyazaki Y, Omori T, Fujitani K, et al. Oral nutritional supplements versus a regular diet alone for body weight loss after gastrectomy: a phase 3, multicenter, open-label randomized controlled trial. Gastric Cancer. 2021;24(5):1150–9.CrossRefPubMed Miyazaki Y, Omori T, Fujitani K, et al. Oral nutritional supplements versus a regular diet alone for body weight loss after gastrectomy: a phase 3, multicenter, open-label randomized controlled trial. Gastric Cancer. 2021;24(5):1150–9.CrossRefPubMed
4.
Zurück zum Zitat Yamamoto K, Takiguchi S, Miyata H, et al. Randomized phase II study of clinical effects of ghrelin after esophagectomy with gastric tube reconstruction. Surgery. 2010;148(1):31–8.CrossRefPubMed Yamamoto K, Takiguchi S, Miyata H, et al. Randomized phase II study of clinical effects of ghrelin after esophagectomy with gastric tube reconstruction. Surgery. 2010;148(1):31–8.CrossRefPubMed
5.
Zurück zum Zitat Yamamoto K, Nagatsuma Y, Fukuda Y, et al. Effectiveness of a preoperative exercise and nutritional support program for elderly sarcopenic patients with gastric cancer. Gastric Cancer. 2017;20(5):913–8.CrossRefPubMed Yamamoto K, Nagatsuma Y, Fukuda Y, et al. Effectiveness of a preoperative exercise and nutritional support program for elderly sarcopenic patients with gastric cancer. Gastric Cancer. 2017;20(5):913–8.CrossRefPubMed
6.
Zurück zum Zitat Komatsu S, Konishi T, Matsubara D, et al. Night home enteral nutrition as a novel enforced and physiologically effective nutrition therapy following total gastrectomy for gastric cancer. Sci Rep. 2022;12(1):14922.CrossRefPubMedPubMedCentral Komatsu S, Konishi T, Matsubara D, et al. Night home enteral nutrition as a novel enforced and physiologically effective nutrition therapy following total gastrectomy for gastric cancer. Sci Rep. 2022;12(1):14922.CrossRefPubMedPubMedCentral
Metadaten
Titel
ASO Author Reflections: Prognostic Impact of Postoperative Oral Nutritional Supplements in Gastric Cancer
verfasst von
Takeshi Omori, MD, PhD
Kazuyoshi Yamamoto, MD, PhD
Yukinori Kurokawa, MD, PhD
Yasuhiro Miyazaki, MD, PhD
Kazumasa Fujitani, MD, PhD
Ryohei Kawabata, MD, PhD
Hiroshi Imamura, MD, PhD
Atsushi Takeno, MD, PhD
Yoshitomo Yanagimoto, MD, PhD
Tsuyoshi Takahashi, MD, PhD
Takuro Saito, MD, PhD
Hidetoshi Eguchi, MD, PhD
Yuichiro Doki, MD, PhD
Publikationsdatum
16.08.2024
Verlag
Springer International Publishing
Erschienen in
Annals of Surgical Oncology / Ausgabe 12/2024
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-024-15774-z

Neu im Fachgebiet Chirurgie

Lohnt sich die Karotis-Revaskularisation?

Die medikamentöse Therapie für Menschen mit Karotisstenosen hat sich in den vergangenen Dekaden verbessert. Braucht es also noch einen invasiven Eingriff zur Revaskularisation der Halsschlagader bei geringem bis moderatem Risiko für einen ipsilateralen Schlaganfall?

Höhere Dosis von Dexamethason senkt Überlebenschancen

Personen mit Hirnmetastasen, die perioperativ höhere kumulative Dosen von Dexamethason erhalten, haben eine schlechtere Prognose. Um die Ergebnisse zu verbessern, bedarf es strengerer Dosierungsschemata.

Appendektomie erhält Remission bei Colitis ulcerosa

Wird der Wurmfortsatz bei Personen mit Colitis ulcerosa entfernt, ist die Rückfallrate um ein Drittel geringer als unter konservativer Behandlung. Auch die Lebensqualität verbessert sich und der Bedarf an Medikamenten nimmt ab.

Op.-Entscheidung bei Divertikulitis: Lebensqualität zählt!

Soll man Menschen, die schon mehrfach schmerzhafte Divertikulitisepisoden durchgemacht haben, eine Op. anbieten? Ein Team aus Helsinki rät, dies von der Lebensqualität abhängig zu machen.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.