Skip to main content
Erschienen in:

26.11.2021 | Maternal-Fetal Medicine

Assessment of normal fetal cortical sulcus development

verfasst von: Berna Aslan Çetin, Rıza Madazlı

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 3/2022

Einloggen, um Zugang zu erhalten

Abstract

Objective

The aim of our study was to investigate the normal cortical sulcus development in fetuses without central nervous system abnormality with transabdominal ultrasonography.

Methods

Our study was planned as a cross-sectional study in our clinic between November 2011 and October 2012. The study group was selected among pregnant women who applied to our hospital for routine antenatal follow-up. Singleton pregnancies, between 15th and 32nd gestational weeks, were included in the study. During the routine fetal ultrasonographic examination of these pregnant women, sylvian sulcus, parietooccipital sulcus, calcarine sulcus, and cingulate sulcus length measurements were taken and the correlation of these values with gestational week was evaluated.

Results

Three hundred and thirty-two patients were included in the study. Sylvian sulcus length, parietooccipital sulcus length, calcarine sulcus length, and cingulate sulcus length could be first measured respectively, at 15th, 17th, 17th and 25th gestational week. We found a positive correlation between gestational age and sylvian sulcus, parietooccipital sulcus, calcarine sulcus, and cingulate sulcus length measurements (p < 0.001).

Conclusion

Sulcal development and cortical maturation can be evaluated prenatally with transabdominal ultrasonography of the central nervous system.
Literatur
1.
Zurück zum Zitat Levine D, Barnes PD (1999) Cortical maturation in normal and abnormal fetuses as assessed with prenatal MR imaging. Radiology 210(3):751–758CrossRef Levine D, Barnes PD (1999) Cortical maturation in normal and abnormal fetuses as assessed with prenatal MR imaging. Radiology 210(3):751–758CrossRef
2.
Zurück zum Zitat Afif A, Trouillas J, Mertens P (2015) Development of the sensorimotor cortex in the human fetus: a morphological description. Surg Radiol Anat 37(2):153–160CrossRef Afif A, Trouillas J, Mertens P (2015) Development of the sensorimotor cortex in the human fetus: a morphological description. Surg Radiol Anat 37(2):153–160CrossRef
3.
Zurück zum Zitat Alves CM, Araujo Júnior E, Nardozza LM et al (2013) Reference ranges for fetal brain fissure development on 3-dimensional sonography in the multiplanar mode. J Ultrasound Med 32(2):269–277CrossRef Alves CM, Araujo Júnior E, Nardozza LM et al (2013) Reference ranges for fetal brain fissure development on 3-dimensional sonography in the multiplanar mode. J Ultrasound Med 32(2):269–277CrossRef
4.
Zurück zum Zitat Rolo LC, Araujo Júnior E, Nardozza LM et al (2011) Development of fetal brain sulci and gyri: assessment through two and three-dimensional ultrasound and magnetic resonance imaging. Arch Gynecol Obstet 283(2):149–158CrossRef Rolo LC, Araujo Júnior E, Nardozza LM et al (2011) Development of fetal brain sulci and gyri: assessment through two and three-dimensional ultrasound and magnetic resonance imaging. Arch Gynecol Obstet 283(2):149–158CrossRef
5.
Zurück zum Zitat Pistorius LR, Stoutenbeek P, Groenendaal F et al (2010) Grade and symmetry of normal fetal cortical development: a longitudinal two- and three-dimensional ultrasound study. Ultrasound Obstet Gynecol 36(6):700–708CrossRef Pistorius LR, Stoutenbeek P, Groenendaal F et al (2010) Grade and symmetry of normal fetal cortical development: a longitudinal two- and three-dimensional ultrasound study. Ultrasound Obstet Gynecol 36(6):700–708CrossRef
6.
Zurück zum Zitat Alonso I, Borenstein M, Grant G et al (2010) Depth of brain fissures in normal fetuses by prenatal ultrasound between 19 and 30 weeks of gestation. Ultrasound Obstet Gynecol 36(6):693–699CrossRef Alonso I, Borenstein M, Grant G et al (2010) Depth of brain fissures in normal fetuses by prenatal ultrasound between 19 and 30 weeks of gestation. Ultrasound Obstet Gynecol 36(6):693–699CrossRef
7.
Zurück zum Zitat Barkovich AJ, Guerrini R, Kuzniecky RI et al (2012) A developmental and genetic classification for malformations of cortical development: update 2012. Brain 135(5):1348–1369CrossRef Barkovich AJ, Guerrini R, Kuzniecky RI et al (2012) A developmental and genetic classification for malformations of cortical development: update 2012. Brain 135(5):1348–1369CrossRef
8.
Zurück zum Zitat Dorovini-Zis K, Dolman CL (1977) Gestational development of brain. Arch Pathol Lab Med 101(4):192–195PubMed Dorovini-Zis K, Dolman CL (1977) Gestational development of brain. Arch Pathol Lab Med 101(4):192–195PubMed
9.
Zurück zum Zitat Kostović I, Judas M, Rados M et al (2002) Laminar organization of the human fetal cerebrum revealed by histochemical markers and magnetic resonance imaging. Cereb Cortex 12(5):536–544CrossRef Kostović I, Judas M, Rados M et al (2002) Laminar organization of the human fetal cerebrum revealed by histochemical markers and magnetic resonance imaging. Cereb Cortex 12(5):536–544CrossRef
10.
Zurück zum Zitat Garel C, Chantrel E, Brisse H et al (2001) Fetal cerebral cortex: normal gestational landmarks identified using prenatal MR imaging. AJNR Am J Neuroradiol 22(1):184–189PubMedPubMedCentral Garel C, Chantrel E, Brisse H et al (2001) Fetal cerebral cortex: normal gestational landmarks identified using prenatal MR imaging. AJNR Am J Neuroradiol 22(1):184–189PubMedPubMedCentral
11.
Zurück zum Zitat Cohen-Sacher B, Lerman-Sagie T, Lev D et al (2006) Sonographic developmental milestones of the fetal cerebral cortex: a longitudinal study. Ultrasound Obstet Gynecol 27(5):494–502CrossRef Cohen-Sacher B, Lerman-Sagie T, Lev D et al (2006) Sonographic developmental milestones of the fetal cerebral cortex: a longitudinal study. Ultrasound Obstet Gynecol 27(5):494–502CrossRef
12.
Zurück zum Zitat Toi A, Lister WS, Fong KW (2004) How early are fetal cerebral sulci visible at prenatal ultrasound and what is the normal pattern of early fetal sulcal development? Ultrasound Obstet Gynecol 24(7):706–715CrossRef Toi A, Lister WS, Fong KW (2004) How early are fetal cerebral sulci visible at prenatal ultrasound and what is the normal pattern of early fetal sulcal development? Ultrasound Obstet Gynecol 24(7):706–715CrossRef
13.
Zurück zum Zitat Droullé P, Gaillet J, Schweitzer M (1984) Maturation of the fetal brain. Echoanatomy: normal development, limits and value of pathology. J Gynecol Obstet Biol Reprod (Paris) 13(3):228–36 Droullé P, Gaillet J, Schweitzer M (1984) Maturation of the fetal brain. Echoanatomy: normal development, limits and value of pathology. J Gynecol Obstet Biol Reprod (Paris) 13(3):228–36
14.
Zurück zum Zitat Chi JG, Dooling EC, Gilles FH (1977) Gyral development of the human brain. Ann Neurol 1(1):86–93CrossRef Chi JG, Dooling EC, Gilles FH (1977) Gyral development of the human brain. Ann Neurol 1(1):86–93CrossRef
15.
Zurück zum Zitat Chen X, Li SL, Luo GY et al (2017) Ultrasonographic characteristics of cortical sulcus development in the human fetus between 18 and 41 weeks of gestation. Chin Med J 130:920–928CrossRef Chen X, Li SL, Luo GY et al (2017) Ultrasonographic characteristics of cortical sulcus development in the human fetus between 18 and 41 weeks of gestation. Chin Med J 130:920–928CrossRef
16.
Zurück zum Zitat Mittal P, Gonçalves LF, Kusanovic JP et al (2007) Objective evaluation of sylvian fissure development by multiplanar 3-dimensional ultrasonography. J Ultrasound Med 26(3):347–353CrossRef Mittal P, Gonçalves LF, Kusanovic JP et al (2007) Objective evaluation of sylvian fissure development by multiplanar 3-dimensional ultrasonography. J Ultrasound Med 26(3):347–353CrossRef
17.
Zurück zum Zitat Monteagudo A, Timor-Tritsch IE (1997) Development of fetal gyri, sulci and fissures: a transvaginal sonographic study. Ultrasound Obstet Gynecol 9(4):222–228CrossRef Monteagudo A, Timor-Tritsch IE (1997) Development of fetal gyri, sulci and fissures: a transvaginal sonographic study. Ultrasound Obstet Gynecol 9(4):222–228CrossRef
18.
Zurück zum Zitat Garel C, Chantrel E, Brisse H et al (2001) Fetal cerebral cortex: normal gestational landmarks identified using prenatal MR imaging. Am J Neuroradiol 22(1):184–189PubMedPubMedCentral Garel C, Chantrel E, Brisse H et al (2001) Fetal cerebral cortex: normal gestational landmarks identified using prenatal MR imaging. Am J Neuroradiol 22(1):184–189PubMedPubMedCentral
19.
Zurück zum Zitat Lan LM, Yamashita Y, Tang Y et al (2000) Normal fetal brain development: MR imaging with a half-Fourier rapid acquisition with relaxation enhancement sequence. Radiology 215(1):205–210CrossRef Lan LM, Yamashita Y, Tang Y et al (2000) Normal fetal brain development: MR imaging with a half-Fourier rapid acquisition with relaxation enhancement sequence. Radiology 215(1):205–210CrossRef
20.
Zurück zum Zitat Abe S, Takagi K, Yamamoto T et al (2003) Assessment of cortical gyrus and sulcus formation using MR images in normal fetuses. Prenat Diagn 23(3):225–231CrossRef Abe S, Takagi K, Yamamoto T et al (2003) Assessment of cortical gyrus and sulcus formation using MR images in normal fetuses. Prenat Diagn 23(3):225–231CrossRef
Metadaten
Titel
Assessment of normal fetal cortical sulcus development
verfasst von
Berna Aslan Çetin
Rıza Madazlı
Publikationsdatum
26.11.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 3/2022
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-021-06334-x

Neu im Fachgebiet Gynäkologie und Geburtshilfe

Keine eingeschränkten Kassenleistungen bei Schwangerschaft nach IVF

Nach privat bezahlter In-vitro-Fertilisation muss die gesetzliche Krankenkasse ein Arzneimittel zum Erhalt der Schwangerschaft bezahlen, so ein Urteil des Sozialgerichts in München.

Medikamente verändern wohl Nährstoffzusammensetzung der Muttermilch

Einige Medikamente wie selektive Serotonin-Wiederaufnahmehemmer können offenbar die Makronährstoffzusammensetzung der Muttermilch verändern. Das birgt möglicherweise gesundheitliche Risiken für manche gestillte Kinder.

CDK4/6-Inhibitoren bei Brustkrebs in die Zweitlinie aufschieben?

Ergebnisse einer Phase-III-Studie sprechen dafür, dass die Behandlung mit CDK4/6-Inhibitoren bei fortgeschrittenem HR-positivem, HER2-negativem Brustkrebs auch auf die Zweitlinie verschoben werden könnte, ohne die onkologischen Ergebnisse zu kompromittieren.

Cannabisextrakt verbessert Antiemese bei Chemotherapie

Sprechen Krebskranke auf die übliche Antiemese während einer Chemotherapie nicht ausreichend an, lohnt sich möglicherweise eine Behandlung mit Cannabisextrakt. In einer Phase-2/3-Studie ließ sich die antiemetische Response mit einem solchen Extrakt erheblich verbessern.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.