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Erschienen in: Archives of Gynecology and Obstetrics 1/2011

01.07.2011 | Materno-fetal Medicine

Assessment of placental blood flow between 22 and 34 weeks of gestation by 3D-sonography power Doppler vascular indices

verfasst von: Rômulo Negrini, Luiz Cláudio de Silva Bussamra, Leonardo da Silva Valladão de Freitas, Edward Araujo Júnior, Sebastião Piato, Luciano Marcondes Machado Nardozza, Antonio Fernandes Moron, Tsutomu Aoki

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 1/2011

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Abstract

Purpose

To analyze and compare the vascular flow in different parts of the placenta of normal pregnant women between 22 and 34 weeks of gestation through three-dimensional power Doppler ultrasonography (3D power Doppler) vascular indices.

Methods

This is a cross-sectional study involving 55 normal pregnant women with gestational ages between 22 and 34 weeks. The vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were obtained using the virtual organ computer-aided analysis (VOCAL) method both in the region of placental cord insertion and the peripheral region of the placenta. The Wilcoxon test was applied, adopting a significance level of 5% to evaluate possible differences in these indices between study areas.

Results

For the three indices examined (VI, FI and VFI), a statistically significant difference was obtained between the insertion of the umbilical cord, designated as the center, and the placental periphery on both the right (p < 0.001 for VI, p = 0.001 for FI and p < 0.001 for VFI) and the left (p < 0.001 for VI, p < 0.001 for FI and p = 0.001 for VFI), taken as the average of the rates obtained in the two peripheries (p < 0.001 for VI, p < 0.001 for FI and p = 0.003 for VFI). Differences were not found when the two peripheral areas were compared or if placenta was anterior or posterior (p > 0.05).

Conclusion

There is a statistically significant difference between the vascular indices obtained with a 3D power Doppler at different points of the placenta.
Literatur
1.
Zurück zum Zitat Simpson JA, Valdez-Cruz LM, Sonn DJ, Murilo A, Tamora T, Chung K (1989) Doppler color flow mapping of simulated in vitro regurgitant jets: evaluation of the effects of orifice sizes and hemodynamic variables. Am Coll Cardiol 13:1195–1207CrossRef Simpson JA, Valdez-Cruz LM, Sonn DJ, Murilo A, Tamora T, Chung K (1989) Doppler color flow mapping of simulated in vitro regurgitant jets: evaluation of the effects of orifice sizes and hemodynamic variables. Am Coll Cardiol 13:1195–1207CrossRef
2.
Zurück zum Zitat Jain SP, Fan PH, Phipot EF (1991) Influence of various instrument settings on the flow information derived from the power mode. Ultrasound Med Biol 17:49–54PubMedCrossRef Jain SP, Fan PH, Phipot EF (1991) Influence of various instrument settings on the flow information derived from the power mode. Ultrasound Med Biol 17:49–54PubMedCrossRef
3.
Zurück zum Zitat Rubin JM, Bude RO, Carson PL, Bree RL, Adler RS (1994) Power Doppler US: a potentially useful alternative to mean frequency-based color Doppler US. Radiology 190:853–856PubMed Rubin JM, Bude RO, Carson PL, Bree RL, Adler RS (1994) Power Doppler US: a potentially useful alternative to mean frequency-based color Doppler US. Radiology 190:853–856PubMed
4.
Zurück zum Zitat Welsh AW, Humphires K, Cosgrove DO, Taylor MJ, Fisk NM (2001) Development of three-dimensional power Doppler ultrasound imaging of fetoplacental vasculature. Ultrasound Med Biol, pp 1161–1170 Welsh AW, Humphires K, Cosgrove DO, Taylor MJ, Fisk NM (2001) Development of three-dimensional power Doppler ultrasound imaging of fetoplacental vasculature. Ultrasound Med Biol, pp 1161–1170
5.
Zurück zum Zitat Stegeman JH (1974) Placental development in the sheep and its relation to fetal development. Bijdragen Tot De Dierkunde (Contib Zool) 44:3 Stegeman JH (1974) Placental development in the sheep and its relation to fetal development. Bijdragen Tot De Dierkunde (Contib Zool) 44:3
6.
Zurück zum Zitat Chang CH, Yu CH, Ko HC, Chang FM, Chen HY (2003) Assessment of normal fetal liver blood flow using quantitative three-dimensional power Doppler ultrasound. Ultrasound Med Biol 29:943–949PubMedCrossRef Chang CH, Yu CH, Ko HC, Chang FM, Chen HY (2003) Assessment of normal fetal liver blood flow using quantitative three-dimensional power Doppler ultrasound. Ultrasound Med Biol 29:943–949PubMedCrossRef
7.
Zurück zum Zitat Cohen LS, Escobar PF, Scharm C, Glimco B, Fishman DA (2001) Three-dimensional power Doppler ultrasound improves the diagnostic accuracy for ovarian cancer prediction. Gynecol Oncol 82:40–48PubMedCrossRef Cohen LS, Escobar PF, Scharm C, Glimco B, Fishman DA (2001) Three-dimensional power Doppler ultrasound improves the diagnostic accuracy for ovarian cancer prediction. Gynecol Oncol 82:40–48PubMedCrossRef
8.
Zurück zum Zitat Pairleitner H, Steiner H, Hosenoeherl G, Staudach A (1999) Threee-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization. Ultrasound Obstet Gynecol 14:139–143PubMedCrossRef Pairleitner H, Steiner H, Hosenoeherl G, Staudach A (1999) Threee-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization. Ultrasound Obstet Gynecol 14:139–143PubMedCrossRef
9.
Zurück zum Zitat Guimarães Filho HA, Dias da Costa LL, Araujo Júnior E, Nardozza LM, Novak PM, Moron AF, Mattar R, Pires CR (2008) Placenta: angiogenesis and vascular assessment through three-dimensional power Doppler ultrasonography. Arch Gynecol Obstet 277:195–200PubMedCrossRef Guimarães Filho HA, Dias da Costa LL, Araujo Júnior E, Nardozza LM, Novak PM, Moron AF, Mattar R, Pires CR (2008) Placenta: angiogenesis and vascular assessment through three-dimensional power Doppler ultrasonography. Arch Gynecol Obstet 277:195–200PubMedCrossRef
10.
Zurück zum Zitat Guimarães Filho HA, Araujo Júnior E, Mattar R, Da Costa LL, de Mello Júnior CF, Nardozza LM, Moron AF (2010) Placental blood flow measured by three-dimensional power Doppler ultrasound at 26 to 35 weeks gestation in normal pregnancies. J Matern Fetal Neonatal Med 23:69–75PubMedCrossRef Guimarães Filho HA, Araujo Júnior E, Mattar R, Da Costa LL, de Mello Júnior CF, Nardozza LM, Moron AF (2010) Placental blood flow measured by three-dimensional power Doppler ultrasound at 26 to 35 weeks gestation in normal pregnancies. J Matern Fetal Neonatal Med 23:69–75PubMedCrossRef
11.
Zurück zum Zitat Mercé LT, Barco MJ, Bau S, Kupesic S, Kurjak A (2005) Assessment of placental vascularization by three-dimensional power Doppler “vascular biopsy” in normal pregnancies. Croat Med J 46:765–771PubMed Mercé LT, Barco MJ, Bau S, Kupesic S, Kurjak A (2005) Assessment of placental vascularization by three-dimensional power Doppler “vascular biopsy” in normal pregnancies. Croat Med J 46:765–771PubMed
12.
Zurück zum Zitat Matijevic R, Kurjak A (2002) The assessment of placental blood vessels by three-dimensional power Doppler ultrasound. J Perinat Med 30:26–32PubMedCrossRef Matijevic R, Kurjak A (2002) The assessment of placental blood vessels by three-dimensional power Doppler ultrasound. J Perinat Med 30:26–32PubMedCrossRef
13.
Zurück zum Zitat Pretorius DH, Nelson TR, Baergen RN, Pai E, Cantrell C (1998) Imaging of placental vasculature using three-dimensional ultrasound and color power Doppler: a preliminary study. Ultrasound Obstet Gynecol 12:45–49PubMedCrossRef Pretorius DH, Nelson TR, Baergen RN, Pai E, Cantrell C (1998) Imaging of placental vasculature using three-dimensional ultrasound and color power Doppler: a preliminary study. Ultrasound Obstet Gynecol 12:45–49PubMedCrossRef
14.
Zurück zum Zitat Yu CH, Chang CH, Ko HC, Chen HC, Chang FM (2003) Assessment of placental fractional moving blood volume using quantitative three-dimensional power Doppler ultrasound. Ultrasound Med Biol 29:19–23PubMedCrossRef Yu CH, Chang CH, Ko HC, Chen HC, Chang FM (2003) Assessment of placental fractional moving blood volume using quantitative three-dimensional power Doppler ultrasound. Ultrasound Med Biol 29:19–23PubMedCrossRef
15.
Zurück zum Zitat Zalud I, Shaha S (2007) Evaluation of utero-placental circulation by three-dimensional Doppler ultrasound in the second trimester of normal pregnancy. J Matern Fetal Neonatal Med, pp 20299–20305 Zalud I, Shaha S (2007) Evaluation of utero-placental circulation by three-dimensional Doppler ultrasound in the second trimester of normal pregnancy. J Matern Fetal Neonatal Med, pp 20299–20305
16.
Zurück zum Zitat Guiot C, Gaglioti P, Oberto M, Piccoli E, Rosato R, Todros T (2008) Is three-dimensional power Doppler ultrasound useful in the assessment of placental perfusion in normal and growth-restricted pregnancy? Ultrasound Obstet Gynecol 31:171–176PubMedCrossRef Guiot C, Gaglioti P, Oberto M, Piccoli E, Rosato R, Todros T (2008) Is three-dimensional power Doppler ultrasound useful in the assessment of placental perfusion in normal and growth-restricted pregnancy? Ultrasound Obstet Gynecol 31:171–176PubMedCrossRef
17.
Zurück zum Zitat Moore TR, Cayle JE (1990) The amniotic fluid index in normal human pregnancy. Am J Obst Gynecol 162:1168–1173 Moore TR, Cayle JE (1990) The amniotic fluid index in normal human pregnancy. Am J Obst Gynecol 162:1168–1173
18.
Zurück zum Zitat Lubchenco LO, Hansman C, Dressler M, Boyd E (1963) Intra-uterine growth as estimated from liveborn birth-weight data at 24 to 42 weeks of gestation. Pediatrics 32:793–800PubMed Lubchenco LO, Hansman C, Dressler M, Boyd E (1963) Intra-uterine growth as estimated from liveborn birth-weight data at 24 to 42 weeks of gestation. Pediatrics 32:793–800PubMed
19.
Zurück zum Zitat Tuuli MG, Houser M, Odibo L, Huster K, Macones GA, Odibo AO (2010) Validation of placental vascular sonobiopsy for obtaining representative placental vascular índices by three-dimensional power Doppler ultrasonography. Placenta 31:192–196PubMedCrossRef Tuuli MG, Houser M, Odibo L, Huster K, Macones GA, Odibo AO (2010) Validation of placental vascular sonobiopsy for obtaining representative placental vascular índices by three-dimensional power Doppler ultrasonography. Placenta 31:192–196PubMedCrossRef
20.
Zurück zum Zitat Raine-Fenning NJ, Welsh W, Jones NW, Bugg G (2008) Methodological considerations for the correct application of quantitative three-dimensional power Doppler angiography. Ultrasound Obstet Gynecol 32:115–117PubMedCrossRef Raine-Fenning NJ, Welsh W, Jones NW, Bugg G (2008) Methodological considerations for the correct application of quantitative three-dimensional power Doppler angiography. Ultrasound Obstet Gynecol 32:115–117PubMedCrossRef
21.
Zurück zum Zitat Chernyavsky IL, Jensen OE, Leach L (2010) A mathematical model of intervillous blood flow in the human placentone. Placenta 31:44–52PubMedCrossRef Chernyavsky IL, Jensen OE, Leach L (2010) A mathematical model of intervillous blood flow in the human placentone. Placenta 31:44–52PubMedCrossRef
Metadaten
Titel
Assessment of placental blood flow between 22 and 34 weeks of gestation by 3D-sonography power Doppler vascular indices
verfasst von
Rômulo Negrini
Luiz Cláudio de Silva Bussamra
Leonardo da Silva Valladão de Freitas
Edward Araujo Júnior
Sebastião Piato
Luciano Marcondes Machado Nardozza
Antonio Fernandes Moron
Tsutomu Aoki
Publikationsdatum
01.07.2011
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 1/2011
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1595-x

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