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Erschienen in: Sport Sciences for Health 2/2016

05.05.2016 | Original Article

Association between angiotensin-converting enzyme gene polymorphism and competitive anxiety in Tunisian athlete

verfasst von: Hela Znazen, Mokhtar Chtara, Marina Butovskaya, Hajer Siala, Taieb Messaoud, Nizar Souissi

Erschienen in: Sport Sciences for Health | Ausgabe 2/2016

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Abstract

Objectives

The present study attempted to test whether the angiotensin-converting enzyme (ACE) genotypes can be associated with precompetitive anxiety that can be potentially used as predictors of athletic performance.

Methods

Eighty-seven track and field athletes (47 males, 40 females; age 20.55 ± 2.22 years; body mass = 77.5 ± 7.1 kg, height = 170.7 ± 5.4 cm) competing at an international level voluntarily participated in this study. The athletes were prospectively classified into two groups according to their genetic polymorphism to physical efforts: endurance group (allele I, n = 48) and power group (allele D, n = 39). Suggested, this genetic predisposition was specifically associated with athlete’s success in sports. Precompetitive anxiety was assessed before competition, and the ACE gene polymorphism was examined by polymerase chain reaction.

Results

It was found that the score performances were associated with psychological factors. In carriers of allele I (related to the endurance), the self-confidence explained 18 % of the variance of score performance (R = 0.46, R 2 = 0.21, adjusted R 2 = 0.15; F = 3.83, p < 0.02). In carriers of allele D (related to the power) (R = 0.30, R 2 = 0.09, adjusted R 2 = 0.01; F = 1.19, p < 0.33), any factors of anxiety can explain the variance of performance.

Conclusion

The current study is the first to interpret the relationship between the ACE gene and somatic anxiety, cognitive anxiety and self-confidence in sportsmen and has provided evidence of association between ACE I/D polymorphism predisposition and success in distance runners. Taking into account the effects of multiple comparisons, this result should be interpreted with caution and needs confirmation in a larger sample.
Literatur
1.
Zurück zum Zitat Keikha BM, Yusof SM, Jourkesh M (2015) The relationship between pre-competition state anxiety components and mood state sub-scales scores and the result of among college athletes through temporal patterning. Int J Sports Sci 5(1):8–15 Keikha BM, Yusof SM, Jourkesh M (2015) The relationship between pre-competition state anxiety components and mood state sub-scales scores and the result of among college athletes through temporal patterning. Int J Sports Sci 5(1):8–15
2.
Zurück zum Zitat Golby J, Sheard M, Lavallee D (2003) A cognitive-behavioral analysis of mental toughness in national rugby league football teams. Percept Mot Skills 2003(96):455–462 Golby J, Sheard M, Lavallee D (2003) A cognitive-behavioral analysis of mental toughness in national rugby league football teams. Percept Mot Skills 2003(96):455–462
3.
Zurück zum Zitat Jones G, Hardy L (1990) Stress in sport: experiences of some elite performers. In: Jones G, Hardy L (eds) Stress and performance in sport. Wiley, Chichester, pp 247–277 Jones G, Hardy L (1990) Stress in sport: experiences of some elite performers. In: Jones G, Hardy L (eds) Stress and performance in sport. Wiley, Chichester, pp 247–277
4.
Zurück zum Zitat Martens R, Burton D, Vealey RS, Bump LA, Smith DE (1990) Development and validation of the Competitive State Anxiety Inventory-2. In: Martens R, Vealey RS, Burton D (eds) Competitive anxiety in sport. Human Kinetics, Champaign, IL, pp 117–190 Martens R, Burton D, Vealey RS, Bump LA, Smith DE (1990) Development and validation of the Competitive State Anxiety Inventory-2. In: Martens R, Vealey RS, Burton D (eds) Competitive anxiety in sport. Human Kinetics, Champaign, IL, pp 117–190
5.
Zurück zum Zitat Neil R, Mellalieu SD, Hanton S (2006) Psychological skills usage and the competitive anxiety response as a function of skill level in rugby union. J Sports Sci Med 5(3):415–423PubMedPubMedCentral Neil R, Mellalieu SD, Hanton S (2006) Psychological skills usage and the competitive anxiety response as a function of skill level in rugby union. J Sports Sci Med 5(3):415–423PubMedPubMedCentral
7.
Zurück zum Zitat Giuseppe L, Umile GL, Nicola M (2010) Genetics and sports. Br Med Bull 93:27–47CrossRef Giuseppe L, Umile GL, Nicola M (2010) Genetics and sports. Br Med Bull 93:27–47CrossRef
8.
Zurück zum Zitat Montgomery HE, Marshall R, Hemingway H, Myerson S, Clarkson P, Dollery C (1998) Human gene for physical performance. Nature 393:221–222CrossRefPubMed Montgomery HE, Marshall R, Hemingway H, Myerson S, Clarkson P, Dollery C (1998) Human gene for physical performance. Nature 393:221–222CrossRefPubMed
9.
Zurück zum Zitat Myerson S, Hemingway H, Budget R, Martin J, Humphries S, Montgomery H (1999) Human angiotensin I-converting enzyme gene and endurance performance. J Appl Physiol 87:1313–1316PubMed Myerson S, Hemingway H, Budget R, Martin J, Humphries S, Montgomery H (1999) Human angiotensin I-converting enzyme gene and endurance performance. J Appl Physiol 87:1313–1316PubMed
10.
Zurück zum Zitat Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F (1990) An insertion/deletion polymorphism in the angiotensin-1-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86:1343–1346CrossRefPubMedPubMedCentral Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F (1990) An insertion/deletion polymorphism in the angiotensin-1-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86:1343–1346CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Woods D, Hickman M, Jamshidi Y, Brull D, Vassiliou Jones A, Humphries S, Montgomery H (2001) Elite swimmers and the D allele of the ACE I/D polymorphism. Hum Genet 108:230–232CrossRefPubMed Woods D, Hickman M, Jamshidi Y, Brull D, Vassiliou Jones A, Humphries S, Montgomery H (2001) Elite swimmers and the D allele of the ACE I/D polymorphism. Hum Genet 108:230–232CrossRefPubMed
12.
Zurück zum Zitat Okuyama S, Sakagawa T, Chaki S, Imagawa Y, Ichiki T, Inagami T (1999) Anxiety-like behavior in mice lacking the angiotensin II type-2 receptor. Brain Res 821:150–159CrossRefPubMed Okuyama S, Sakagawa T, Chaki S, Imagawa Y, Ichiki T, Inagami T (1999) Anxiety-like behavior in mice lacking the angiotensin II type-2 receptor. Brain Res 821:150–159CrossRefPubMed
13.
Zurück zum Zitat Ichiki T, Labosky PA, Shiota C, Okuyama S, Imagawa Y, Fogo A, Niimura F, Ichikawa I, Hogan BL, Inagami T (1995) Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature 377:748–750CrossRefPubMed Ichiki T, Labosky PA, Shiota C, Okuyama S, Imagawa Y, Fogo A, Niimura F, Ichikawa I, Hogan BL, Inagami T (1995) Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature 377:748–750CrossRefPubMed
14.
Zurück zum Zitat Gard PR, Mandy A, Sutcliffe MA (1999) Evidence of a possible role of altered angiotensin function in the treatment, but not etiology, of depression. Biol Psychiatry 45:1030–1034CrossRefPubMed Gard PR, Mandy A, Sutcliffe MA (1999) Evidence of a possible role of altered angiotensin function in the treatment, but not etiology, of depression. Biol Psychiatry 45:1030–1034CrossRefPubMed
15.
Zurück zum Zitat Vuckovic A, Cohen BM, Zubenko GS (1991) The use of captopril in treatment-resistant depression: an open trial. J Clin Psychopharmacol 11:395–396CrossRefPubMed Vuckovic A, Cohen BM, Zubenko GS (1991) The use of captopril in treatment-resistant depression: an open trial. J Clin Psychopharmacol 11:395–396CrossRefPubMed
16.
Zurück zum Zitat Arinami T, Li L, Mitsushio H, Itokawa M, Hamaguchi H, Toru M (1996) An insertion/deletion polymorphism in the angiotensin converting enzyme gene is associated with both brain substance P contents and affective disorders. Biol Psychiatry 40:1122–1127CrossRefPubMed Arinami T, Li L, Mitsushio H, Itokawa M, Hamaguchi H, Toru M (1996) An insertion/deletion polymorphism in the angiotensin converting enzyme gene is associated with both brain substance P contents and affective disorders. Biol Psychiatry 40:1122–1127CrossRefPubMed
17.
Zurück zum Zitat Pauls J, Bandelow B, Ruther E, Kornhuber J (2000) Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder. J Neural Transm 107:1361–1366CrossRefPubMed Pauls J, Bandelow B, Ruther E, Kornhuber J (2000) Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder. J Neural Transm 107:1361–1366CrossRefPubMed
18.
Zurück zum Zitat Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Muller CR, Hamer DH, Murphy DL (1996) Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274:1527–1531CrossRefPubMed Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Muller CR, Hamer DH, Murphy DL (1996) Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274:1527–1531CrossRefPubMed
19.
Zurück zum Zitat Znazen H, Chatara M, Hammoudi S, Briki W, Butovskaya M, Lazebny O, Souissi N (2016) The relative contributions of genetic predispositions on the determination of personality trait related to optimal performance medicina dello sport (in press) Znazen H, Chatara M, Hammoudi S, Briki W, Butovskaya M, Lazebny O, Souissi N (2016) The relative contributions of genetic predispositions on the determination of personality trait related to optimal performance medicina dello sport (in press)
20.
Zurück zum Zitat Wiggins MS (1998) Anxiety intensity and direction: preperformance temporal patterns and expectations in athletes. J Appl Sport Psychol 10(2):201–211CrossRef Wiggins MS (1998) Anxiety intensity and direction: preperformance temporal patterns and expectations in athletes. J Appl Sport Psychol 10(2):201–211CrossRef
21.
Zurück zum Zitat Kais K, Raudsepp L (2005) Intensity and direction of competitive state anxiety, self-confidence and athletic performance. Kinesiology 37(1):13–20 Kais K, Raudsepp L (2005) Intensity and direction of competitive state anxiety, self-confidence and athletic performance. Kinesiology 37(1):13–20
22.
Zurück zum Zitat Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning. Cold Spring Harbor. Sci Sports Exerc 45:892–900 Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning. Cold Spring Harbor. Sci Sports Exerc 45:892–900
23.
Zurück zum Zitat Eysenck HJ, Eysenck SBG (1968) Manual for the Eysenck Personality Inventory. Educational and Industrial Testing Service, San Diego Eysenck HJ, Eysenck SBG (1968) Manual for the Eysenck Personality Inventory. Educational and Industrial Testing Service, San Diego
24.
Zurück zum Zitat Zeqing W, Jun Y, Hongwu Z (2003) Correlation between servicemen personalities and the polymorphism of ace gene. Med J Chin People Lib Army 7:16 Zeqing W, Jun Y, Hongwu Z (2003) Correlation between servicemen personalities and the polymorphism of ace gene. Med J Chin People Lib Army 7:16
25.
Zurück zum Zitat McCann SC, Murphy SM, Raedeke TD (1992) The effect of performance setting and individual differences on the anxiety-performance relationship for elite cyclists. Anx Stress Int J 5(2):177–187CrossRef McCann SC, Murphy SM, Raedeke TD (1992) The effect of performance setting and individual differences on the anxiety-performance relationship for elite cyclists. Anx Stress Int J 5(2):177–187CrossRef
26.
Zurück zum Zitat Woodman T, Hardy L (2003) The relative impact of cognitive anxiety and self-confidence upon sport performance: a meta-analysis. J Sports Sci 21:443–457CrossRefPubMed Woodman T, Hardy L (2003) The relative impact of cognitive anxiety and self-confidence upon sport performance: a meta-analysis. J Sports Sci 21:443–457CrossRefPubMed
27.
Zurück zum Zitat Parfitt G, Pates J (1999) The effects of cognitive and somatic anxiety and self-confidence on components of performance during competition. J Sports Sci 17:351–356CrossRefPubMed Parfitt G, Pates J (1999) The effects of cognitive and somatic anxiety and self-confidence on components of performance during competition. J Sports Sci 17:351–356CrossRefPubMed
28.
Zurück zum Zitat Borwin B, Kristina S, Jutta P, Katharina D, Dirk W, Peter F (2010) Insertion/deletion polymorphism in the gene for angiotensin converting enzyme (ACE) in panic disorder: a gender-specific effect? World J Biol Psychiatry 11:66–70CrossRef Borwin B, Kristina S, Jutta P, Katharina D, Dirk W, Peter F (2010) Insertion/deletion polymorphism in the gene for angiotensin converting enzyme (ACE) in panic disorder: a gender-specific effect? World J Biol Psychiatry 11:66–70CrossRef
29.
Zurück zum Zitat Ouyang WC, Wang YC, Hong CJ, Cheng CY, Tsai SJ (2001) Association study of angiotensin-converting enzyme gene polymorphism with schizophrenia and polydipsia. Neuropsychobiology 44:31–35CrossRefPubMed Ouyang WC, Wang YC, Hong CJ, Cheng CY, Tsai SJ (2001) Association study of angiotensin-converting enzyme gene polymorphism with schizophrenia and polydipsia. Neuropsychobiology 44:31–35CrossRefPubMed
30.
Zurück zum Zitat Alvarez R, Alvarez V, Lahoz CH et al (1999) Angiotensin converting enzyme and endothelial nitric oxide synthase DNA polymorphisms and late onset Alzheimer’s disease. J Neurol Neurosurg Psychiatry 67(6):733–736CrossRefPubMedPubMedCentral Alvarez R, Alvarez V, Lahoz CH et al (1999) Angiotensin converting enzyme and endothelial nitric oxide synthase DNA polymorphisms and late onset Alzheimer’s disease. J Neurol Neurosurg Psychiatry 67(6):733–736CrossRefPubMedPubMedCentral
31.
Zurück zum Zitat Alvarez R, Terrado SN, Ortolano R et al (2000) Genetic variation in the renin-angiotensin system and athletic performance. Eur J Appl Physiol 82:117–120CrossRefPubMed Alvarez R, Terrado SN, Ortolano R et al (2000) Genetic variation in the renin-angiotensin system and athletic performance. Eur J Appl Physiol 82:117–120CrossRefPubMed
32.
Zurück zum Zitat Weinberg RS, Gould D (2007) Foundations of sport and exercise psychology. Human Kinetics, Champaign, IL Weinberg RS, Gould D (2007) Foundations of sport and exercise psychology. Human Kinetics, Champaign, IL
33.
Zurück zum Zitat Paquet Y, Groslambert A, Tougne J (2008) Caractéristiques Psychologiques des coureurs qui négocient avec succès le passage des catégories Junior-Espoirs Homme en cyclisme sur route. Actes de seminaires de la FFC, Bourges Paquet Y, Groslambert A, Tougne J (2008) Caractéristiques Psychologiques des coureurs qui négocient avec succès le passage des catégories Junior-Espoirs Homme en cyclisme sur route. Actes de seminaires de la FFC, Bourges
34.
Zurück zum Zitat Lane M, Sewell DF, Terry PC, Bartram D, Nesti MS (1999) Confirmatory factor analysis of the Competitive State Anxiety Inventory-2. J Sports Sci 17:505–512CrossRefPubMed Lane M, Sewell DF, Terry PC, Bartram D, Nesti MS (1999) Confirmatory factor analysis of the Competitive State Anxiety Inventory-2. J Sports Sci 17:505–512CrossRefPubMed
35.
Zurück zum Zitat Powell K, (2009). The impact of event group and gender on the relationship between sport anxiety and performance in track and field athletes. Thesis (M.A.) abstract, The American University, 48-02, p 1261 Powell K, (2009). The impact of event group and gender on the relationship between sport anxiety and performance in track and field athletes. Thesis (M.A.) abstract, The American University, 48-02, p 1261
36.
Zurück zum Zitat Edwards T, Hardy L (1996) The interactive effects of intensity and direction of cognitive and somatic anxiety and self-confidence upon performance. J Sport Exerc Psychol 18:296–312 Edwards T, Hardy L (1996) The interactive effects of intensity and direction of cognitive and somatic anxiety and self-confidence upon performance. J Sport Exerc Psychol 18:296–312
37.
Zurück zum Zitat Jones G (1991) Recent developments and current issues in competitive anxiety in sport. Sport Psychol 4:152–155 Jones G (1991) Recent developments and current issues in competitive anxiety in sport. Sport Psychol 4:152–155
Metadaten
Titel
Association between angiotensin-converting enzyme gene polymorphism and competitive anxiety in Tunisian athlete
verfasst von
Hela Znazen
Mokhtar Chtara
Marina Butovskaya
Hajer Siala
Taieb Messaoud
Nizar Souissi
Publikationsdatum
05.05.2016
Verlag
Springer Milan
Erschienen in
Sport Sciences for Health / Ausgabe 2/2016
Print ISSN: 1824-7490
Elektronische ISSN: 1825-1234
DOI
https://doi.org/10.1007/s11332-016-0280-2

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