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The International Journal of Cardiovascular Imaging

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16.06.2017 | Original Paper

Association between flow skewness and aortic dilatation in patients with aortic stenosis

verfasst von: Hojin Ha, Hyun Jung Koo, June Goo Lee, Guk Bae Kim, Jihoon Kweon, Sang Joon Lee, Joon Won Kang, Tae Hwan Lim, Dae Hee Kim, Jong Min Song, Duk Hyun Kang, Jae Kwan Song, Young Hak Kim, Namkug Kim, Dong Hyun Yang

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 12/2017

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Abstract

We investigated association between hemodynamic characteristics and aortic dilatation in patients with severe aortic stenosis (AS). Eighty patients with severe AS (mean age, 67.2 ± 12.5 years) who underwent multi-detector computed tomography and phase-contrast magnetic resonance imaging at the ascending aorta were retrospectively analyzed. Patients with an ascending aorta diameter >4 cm had a significantly higher forward flow rate at systole (28.5 ± 6.0 vs. 36.2 ± 8.6 L min, P < 0.001), and retrograde flow rate at systole (11.3 ± 4.2 vs. 18.8 ± 5.8 L min, P < 0.001), fractional reverse ratio (a ratio of retrograde flow rate to forward flow rate; 34.1 ± 11.9% vs. 43.5 ± 18.0%, P = 0.014), flow skewness R_skewness (a ratio of sum of forward and retrograde systole flow to net systole flow rate; 2.4 ± 0.7 vs. 3.2 ± 1.0, P < 0.001). The presence of bicuspid aortic valve (BAV; odds ratio [OR] 72.01, 95% confidence interval [CI] 10.57–490.46, P < 0.001), Left ventricular mass index (LVMI; OR 1.02 /g/m²; CI 1.00–1.04, P = 0.043) and R_skewness (OR 5.6 per 1, 95% CI 1.8–17.1, P = 0.001) were associated with aortic dilatation. BAV, LVMI, and increased R_skewness in the ascending aorta are associated with aortic dilatation in patients with AS.

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Titel: Association between flow skewness and aortic dilatation in patients with aortic stenosis
verfasst von: Hojin Ha
Hyun Jung Koo
June Goo Lee
Guk Bae Kim
Jihoon Kweon
Sang Joon Lee
Joon Won Kang
Tae Hwan Lim
Dae Hee Kim
Jong Min Song
Duk Hyun Kang
Jae Kwan Song
Young Hak Kim
Namkug Kim
Dong Hyun Yang
Publikationsdatum: 16.06.2017
Verlag: Springer Netherlands
Erschienen in: The International Journal of Cardiovascular Imaging / Ausgabe 12/2017
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI: https://doi.org/10.1007/s10554-017-1196-x

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