Anzeige
Erschienen in:
14.04.2021 | Short Report
Association between perihematomal perfusion and intracerebral hemorrhage shape
Erschienen in: Neuroradiology | Ausgabe 9/2021
Einloggen, um Zugang zu erhaltenAbstract
Purpose
The pathophysiological determinants of irregular intracerebral hemorrhage (ICH) shape are unclear. We aimed at characterizing the relationship between perihematomal perfusion and ICH shape.
Methods
A single-center cohort of patients with primary ICH was analyzed. Patients underwent computed tomography perfusion within 6 h from onset. Cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT) were calculated in the manually outlined perihematomal low-density region. ICH shape was rated on baseline non-contrast CT following international consensus criteria, and predictors of irregular shape were explored with logistic regression.
Results
A total of 150 patients were included, of whom 66 (44%) had irregular shape. Perihematomal CBF was lower in irregular ICH (median 23 vs 35 mL/100 g/min, p<0.001). CBF<20 mL/100 g/min was independently associated with irregular shape (odds ratio 9.67, 95% CI 2.42–38.69, p=0.001).
Conclusion
Our findings suggest that perihematomal hypoperfusion may contribute to the CT appearance of acute ICH.