Erschienen in:
04.08.2017 | Research Letter
Association of fetuin-A to adiponectin ratio with metabolic syndrome: a cross-sectional study
verfasst von:
Huixiang Ju, Zhongwei Zhou, Mingzhong Sun, Hongmei Chen
Erschienen in:
Endocrine
|
Ausgabe 1/2017
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Excerpt
Fetuin-A is a protein which is an endogenous inhibitor inhibiting insulin receptor tyrosine kinase causing insulin resistance [
1]. Increased fetuin-A expression has also been shown to be involved in excessive fat accumulation, impaired glucose tolerance and inflammatory processes [
2,
3]. In the past years, a large body of research has demonstrated a strong positive correlation between increased fetuin-A levels and metabolic syndrome (MS) and its components [
4,
5]. In contrast to fetuin-A, adiponectin is a protein with protective features against MS which is recognized as a critical regulator of insulin resistance, systemic inflammation, and glucose and lipid metabolism [
6,
7]. A recent study revealed reduced circulating adiponectin levels are associated with the MS independently of obesity, lipid indices and serum insulin levels [
8]. …
